Dragging Ras Back in the Ring
Cited by (801)
Items 601–700 of 801
- Excavation of FOSL1 in the Ruins of KRAS-Driven Lung CancerVenkateshwar G. Keshamouni · 2018 · American Journal of Respiratory Cell and Molecular Biology
- A dataset describing a suite of novel antibody reagents for the RAS signaling networkRegine M. Schoenherr, Dongqing Huang, Uliana J. Voytovich, Richard G. Ivey, Jacob J. Kennedy, Richard G. Saul, Simona Colantonio, Rhonda R. Roberts, Joseph G. Knotts, Jan A. Kaczmarczyk et al. · 2019 · Scientific Data
- Targeting Monounsaturated Fatty Acid Metabolism for Radiosensitization of KRAS Mutant 3D Lung Cancer ModelsShan Lu, Xiao Pan, Eva Volckova, Anjali Shinde, Schuyler R. Fuller, Regina K. Egan, Jianli Ma, Jong Kung, Christopher J. Ott, Aaron N. Hata et al. · 2025 · Molecular Cancer Therapeutics
- Why isn’t an oncogenic mutation in KRAS enough to induce and sustain transformation?Juan Iovanna, Nelson Dusetti · 2026 · Critical Reviews in Oncology/Hematology
- Argonaute 2 modulates EGFR–RAS signaling to promote mutantHRASandNRAS-driven malignanciesRonald F. Siebenaler, Seema Chugh, Jessica J. Waninger, Vijaya L. Dommeti, Carson Kenum, Malay K. Mody, Anudeeta Gautam, Nidhi Patel, Alec Chu, Pushpinder Bawa et al. · 2022 · PNAS Nexus
- Synergy and anti‐cooperativity in allostery: Molecular dynamics study of WT and oncogenic KRAS‐RGL1Aysima Hacisuleyman, Burak Erman · 2023 · Proteins Structure Function and Bioinformatics
- Gene signatures from pancreatic cancer tumor and stromal cells predict disease outcomeFilippos Kottakis, Nabeel M. Bardeesy · 2015 · Nature Genetics
- RAS oncogenes direct metastasisΜάγδα Σπέλλα, Antonia Marazioti, Kristina A. M. Arendt, Georgios T. Stathopoulos · 2017 · Molecular & Cellular Oncology
- 4′‐C‐Aminoethoxy‐Modified DNAs Exhibit Increased Nuclease Resistance, Sustained RNase H Activity, and Inhibition of KRAS Gene ExpressionYuki Katsuzaki, Ryo Tsukimura, Akash Chandela, Tokuhiro Chano, Yoshihito Ueno · 2022 · Chemistry & Biodiversity
- Cancer Spheroid Proliferation Is Suppressed by a Novel Low-toxicity Compound, Pyra-Metho-Carnil, in a Context-independent MannerKazumasa Yoshida, Kensuke Nishi, Shuhei Ishikura, Kazuhiko Nakabayashi, Ryo Yazaki, TAKASHI OHSHIMA, Masahiko Suenaga, Senji Shirasawa, Toshiyuki Tsunoda · 2022 · Anticancer Research
- Alisertib exerts KRAS allele‑specific anticancer effects on colorectal cancer cell linesBaojun Ren, 高卓维, Kehong Zheng, Yong Yang, Pengfei Su, Qimei Luo, Jing Feng, Luo Zhentao, Yan Geng, Yongle Ju et al. · 2023 · Experimental and Therapeutic Medicine
- In silico design of a lipid-like compound targeting KRAS4B-G12D through non-covalent bondsHuixia Lu, Zheyao Hu, Jordi Faraudo, Jordi Martí · 2023 · Nanoscale
- Adapting recombinant bacterial alkaline phosphatase for nucleotide exchange of small GTPasesPeter H. Frank, Min Hong, Brianna Higgins, Shelley C. Perkins, Troy E. Taylor, Vanessa E. Wall, Matthew R. Drew, Timothy J. Waybright, William Gillette, Dominic Esposito et al. · 2024 · Protein Expression and Purification
- Computational analysis of treatment resistant cancer cellsAlexandre Matov · 2026 · Frontiers in Cell and Developmental Biology
- Optimizing Single Agent Panitumumab Therapy in Pre-Treated Advanced Colorectal CancerGiampietro Gasparini, Fiamma Buttitta, Mario Rosario D'Andrea, Salvatore Tumolo, Angela Buonadonna, Ida Pavese, Stefano Sergio Cordio, Michele De Tursi, Stefania Mosconi, Luciano Stumbo et al. · 2014 · Neoplasia
- Recent Advances in Developing K-Ras Plasma Membrane Localization InhibitorsNa Ye, Qingfeng Xu, Wanwan Li, Pingyuan Wang, Jia Zhou · 2019 · Current Topics in Medicinal Chemistry
- Mechanisms and Markers of Clinical RadioresistanceMichael Sargent Binkley, Maximilian Diehn, Iris Eke, Henning Willers · 2020 · Cancer drug discovery and develogment/Cancer drug discovery and development
- KRAS-specific antibody binds to KRAS protein inside colorectal adenocarcinoma cells and inhibits its localization to the plasma membraneKuen Kuen Lam, Yee Syuen Low, Michelle Lo, Michelle Wong, Choong Leong Tang, Emile Tan, Aik Yong Chok, Isaac Seow‐En, Siew Heng Wong, Peh Yean Cheah · 2023 · Frontiers in Oncology
- RAS mutations – for better or for worse in multiple myeloma?Ellen Leich, Torsten Steinbrunn · 2015 · Leukemia & lymphoma/Leukemia and lymphoma
- Comprehensive Validation of Snapback Primer-Based Melting Curve Analysis to Detect Nucleotide Variation in the Codon 12 and 13 of KRAS GeneQunfeng Zhang, Yiqiao Du, Xinju Zhang, Zhihua Kang, Ming Guan, Zhiyuan Wu · 2018 · BioMed Research International
- Targeting the Architecture of Deregulated Protein Complexes in CancerEduard Stefan, Jakob Troppmair, Klaus Bister · 2017 · Advances in protein chemistry and structural biology
- Towards an Integrated Understanding of Epidermal Growth Factor Receptor Biology for Radiation Therapy: Integrins EnterHenning Willers, Theodore Sunki Hong · 2015 · JNCI Journal of the National Cancer Institute
- Identification of Small-Molecule Inhibitors that Block the GTP-Binding Pocket of K-Ras and Other Members of the Ras Superfamily of Small GTPasesLuca Carta, Rebecca Hutcheson, Carolina L. Bigarella, Sufang Zhang, Simon A. Davis, Michael J. Rudolph, Charles H. Reynolds, Matthias Quick, Theresa M. Williams, Michael Schmertzler et al. · 2025 · Molecular Cancer Therapeutics
- Double trouble: cytosolic and nuclear IKKα in cancerKirsty Tinto, Margaret Cunningham, Robin J. Plevin · 2025 · Open Biology
- Diffusion-based determination of protein homodimerization on reconstituted membrane surfacesTyler A. Jepson, Jean K. Chung · 2021 · BMB Reports
- Combined HASPIN and mTOR inhibition is synergistic against KRAS-driven carcinomasChenyue Xu, Qiongmei Gao, ZhengMing Wu, Weijuan Lou, Xiaoyan Li, Nianhong Wang, Nianhong Wang, Qingquan Li · 2022 · Translational Oncology
- Optimized conditions for GTP loading of RasKimberly J. Vish, Maxum E. Paul, Asha P. Rollins, Titus J. Boggon · 2025 · Journal of Biological Chemistry
- p38 links RAS to GATA2Christian Baumgärtner, Manuela Baccarini · 2014 · EMBO Reports
- Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene FunctionSantiago Nahuel Villegas, Dolors Ferrés-Marcó, María Domínguez · 2019 · Advances in experimental medicine and biology
- Growth Suppression of Cancer Spheroids With Mutated KRAS by Low-toxicity Compounds from Natural ProductsSayuri Hashimoto, Masayoshi Nagai, Kensuke Nishi, Shuhei Ishikura, Kazuhiko Nakabayashi, Ryo Yazaki, TAKASHI OHSHIMA, Masahiko Suenaga, Senji Shirasawa, Toshiyuki Tsunoda · 2021 · Anticancer Research
- ERK2 Mutations Affect Interactions, Localization, and DimerizationClinton A. Taylor, Kevin W. Cormier, Ana Martín-Vega, Svetlana A. Earnest, Steve Stippec, Chonlarat Wichaidit, Melanie H. Cobb · 2023 · Biochemistry
- In vivo KRAS G12D/V degradation mediated by CANDDY using a modified proteasome inhibitorSatoshi Imanishi, Lijuan Huang, Shoko Itakura, Masamichi Ishizaka, Yoichi Iwasaki, Tomohiro Yamaguchi, Etsuko Miyamoto‐Sato · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Elucidating Ras protein as a dual therapeutic target for inflammation and cancer: a reviewParmar Keshri Nandan, Sivaraman Jayanthi · 2025 · Discover Oncology
- Targeting oncogenic K-RAS mutants with small-molecule degrader XMU-MP-9 through NEDD4-1Taoling Zeng, Tingting Jiang, Baoding Zhang, Ting Zhang, Wanjun Dai, Xun Yin, Yunzhan Li, Zhuoran Yu, Caiming Wu, Yaying Wu et al. · 2025 · Acta Pharmaceutica Sinica B
- Evaluation of a Novel Pan-RAS Inhibitor in 3D Bioprinted Tumor ModelsDaniela Farias de Nóbrega, Logan C. Eiler, Parmanand Ahirwar, Sonika Nallapu, Urvi P. Rawal, Chelsea L. Crawford, Donald J. Buchsbaum, Adam B. Keeton, Yulia Y. Maxuitenko, Xi Chen et al. · 2025 · Cancers
- Impact of KRAS-G12 Mutations on the KRAS-GTP Bound Conformational Dynamics: Structure, Free Energy Barriers and Drugging PocketsZheyao Hu, Zigan Sha, Jordi Martı́, Shujuan Guo, Sheng‐ce Tao · 2026 · JACS Au
- Molecular glue degraders: Rational design, specificity engineering, and advanced deliveryLieen Ma, Ning Wang, Jingjing Zhu, Lingjie Wu, Shan He, Bin Zhang · 2026 · Acta Pharmaceutica Sinica B
- Current Strategies and Future Dimensions in the Development of KRAS Inhibitors for Targeted Anticancer TherapyLaura D'Alessio‐Sands, Joshua Gaynier, Victoria Michel‐Milian, Ayodeji A. Agbowuro, Christopher M. Brackett · 2025 · Drug Development Research
- Targeting MDM2, RAS, and PCNA for cancer targeted therapy: pan-cancer approaches vs. cancer-specific strategiesWei Wang, Abigail Alley, Na Sun, Meheret Tadesse, Xinshi Wang, Ruiwen Zhang · 2025 · Frontiers in Pharmacology
- Doubling Down on Mutant RAS Can MEK or Break LeukemiaZuzana Tóthová, Benjamin L. Ebert · 2017 · Cell
- KRAS: Structure, function, and development of anticancer drugsDolly A. Parasrampuria, Alex Yu, Nahor Haddish‐Berhane · 2020 · Elsevier eBooks
- Targeting K-Ras Mutations Show Promise Towards Ending Ras’s “Undruggable” EraPaul D. Adams, Djamali Muhoza · 2022 · Protein and Peptide Letters
- Targeting Oncogenic Driver Mutations in Lung CancerMatthew H. Lee, Fawzi Abu Rous, Alain Borczuk, Stephen V. Liu, Shirish M. Gadgeel, Balázs Halmos · 2023 · Cambridge University Press eBooks
- 143D, a novel selective KRASG12C inhibitor exhibits potent antitumor activity in preclinical modelsLansong Xu, Su-xin Zheng, Lianghe Mei, Kexin Yang, Ya‐Fang Wang, Qiang Zhou, Xiangtai Kong, Ming-yue Zheng, Hualiang Jiang, Chengying Xie · 2023 · Acta Pharmacologica Sinica
- Cytosolic EpCAM cooperates with H-Ras to regulate epithelial to mesenchymal transition through ZEB1Fatma A. Omar, Taylor C. Brown, William E. Gillanders, Timothy P. Fleming, Michael A. Smith, Ross Macrae Bremner, Narendra V. Sankpal · 2023 · PLoS ONE
- Probing the Electrostatic Effects of H-Ras Tyrosine 32 Mutations on Intrinsic GTP Hydrolysis Using Vibrational Stark Effect Spectroscopy of a Thiocyanate ProbeJackson C. Fink, Danielle Landry, Lauren J. Webb · 2024 · Biochemistry
- GradientScanSurv—An exhaustive association test method for gene expression data with censored survival outcomeMing Yi, Ruoqing Zhu, Robert M. Stephens · 2018 · PLoS ONE
- Therapeutic Targeting of RAS Mutant CancersEdward C. Stites, Kendra V. Paskvan, Shumei Kato · 2022 · Cambridge University Press eBooks
- MicroRNA in Breast Cancer — Gene Regulators and Targets for Novel TherapiesYunus A. Luqmani, Maitham Abbas Khajah · 2015 · InTech eBooks
- Interaction of a novel fluorescent GTP analogue with the small G-protein K-RasSeigo Iwata, Kaori Masuhara, Nobuhisa Umeki, Yasushi Sako, Shinsaku Maruta · 2015 · The Journal of Biochemistry
- The Endeavours in RAS Inhibition - the Past, Present, and FutureJaveena Hussain, Sivapriya Kirubakaran, Srimadhavi Ravi · 2020 · Current Topics in Medicinal Chemistry
- Mutant Allele Imbalance in CancerCraig M. Bielski, Barry S. Taylor · 2020 · Annual Review of Cancer Biology
- Somatic mutations in colorectal cancer: regional experienceNikolai A. Ognerubov, Elena N. Ezhova · 2022 · Consilium Medicum
- Ras inhibition by trametinib treatment in Drosophila attenuates gut pathology in females and extends lifespan in both sexesJennifer C. Regan, Yuxuan Lu, Ekin Bolukbasi, Mobina Khericha, Linda Partridge · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
- Targeting Hyperactive Ras Signaling in Pediatric CancerAnya L. Levinson, Kevin Shannon, Benjamin J. Huang · 2024 · Cold Spring Harbor Perspectives in Medicine
- In Vivo Efficacy of ABHD17 Inhibition Validates the Palmitoylation Cycle as a Therapeutic Target in NRAS -Mutant CancerMatthew Decker, Benjamin J. Huang, Timothy B. Ware, Christopher D. Boone, Michelle Tang, Julia Ybarra, Matthew J. Sale, Rony A. Francois, Aishwarya C. Ballapuram, Katrine A. Taran et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Time-Resolved Crystallography Reveals the Mechanisms of GTP hydrolysis for N-RAS and the Oncogenic Mutants G12C, G12V and Q61LGuowu Lin, Paola Zinser Peniche, Xiaohong Zhou, Ulises Santiago, Igor V. Kurnikov, Silvia Russi, Brisa Caroline Alves Chagas, M.E. Sharpe, Dennis P. Stegmann, Shannon A. Heinig et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- RESEARCH CHALLENGES IN STAGE III AND IV RAS-ASSOCIATED CANCERS: A Narrative Review of the Complexities and Functions of the Family of RAS Genes and Ras Proteins in Housekeeping and TumorigenesisRichard A. McDonald, Armando Varela-Ramı́rez, Amanda K. Ashley · 2025 · Biology
- Tumor suppressor genes and KRAS G12C inhibitor resistance in non-small cell lung cancerLinsha Zhu, Xiangbo Jia, Lei Xu, Li Chen, Xiangning Fu, Hua Yan, Bo Ai, Shu Peng · 2025 · iScience
- Development of Scalable Synthesis of RAS Inhibitor’s Indole Building Block via Flow ChemistrySudarshan Debnath, Wencun Wang, Songren Xue, Shovan Mondal, Xingyong Zhu · 2025 · Organic Process Research & Development
- Induction of MAP kinase phosphatase 3 through Erk/MAP kinase activation in three oncogenic Ras (H-, K- and N-Ras)-expressing NIH/3T3 mouse embryonic fibroblast cell linesJaeHyung Koo, Sen Wang, NaNa Kang, Sun Jin Hur, Young Yil Bahk · 2016 · BMB Reports
- Sensitivity of Oncogenic KRAS-Expressing Cells to CDK9 InhibitionLo Lai, Viviane Brel, Kanika Sharma, Julia Frappier, Nadia Le-Henanf, Bertrand Vivet, Nicolas Muzet, Emilie Schell, Renaud Morales, E.K. Rooney et al. · 2021 · SLAS DISCOVERY
- Targeting KRAS and SHP2 signaling pathways for immunomodulation and improving treatment outcomes in solid tumorsPriyanka Sahu, Ankita Mitra, Anirban Ganguly · 2024 · International review of cytology
- The research advances in Kirsten rat sarcoma viral oncogene homolog (KRAS)-related cancer during 2013 to 2022: a scientometric analysisYujie Huang, Daitian Zheng, Zhongming Zhou, Haiting Wang, Yanpo Li, Huihui Zheng, Jianhui Tan, Jingyao Wu, Qiuping Yang, Huiting Tian et al. · 2024 · Frontiers in Oncology
- Cancer research is not correlated with driver gene mutation burdensGaurav Mendiratta, David Liarakos, Melinda M. Tong, Satoko Ito, Eugene Ke, George Goshua, Edward C. Stites · 2024 · Med
- Design, synthesis, and evaluation of dual son of sevenless 1 (SOS1) and epidermal growth factor receptor (EGFR) inhibitors for the treatment of cancersYi Zeng, Chenyang Huang, Qiangqiang Hou, Wenhua Jiang, Jiaqi Cheng, Xiaoxing Wu · 2024 · Bioorganic Chemistry
- The prominent pervasive oncogenic role and tissue specific permissiveness of RAS gene mutationsMing Yi, Daniel R. Soppet, Frank P. McCormick, Dwight V. Nissley · 2024 · Scientific Reports
- Nanoparticles Bounded to Interfering RNAs as a Therapy for Pancreatic Cancer: A Systematic ReviewPatricia Lara, Francisco Quiñonero, Raúl Ortíz, Jose Carlos Prados, Consolación Melguizo · 2024 · Wiley Interdisciplinary Reviews Nanomedicine and Nanobiotechnology
- Unraveling atomic-scale mechanisms of GDP extraction catalyzed by SOS1 in KRAS-G12 and KRAS-D12 oncogenesZheyao Hu, Jordi Martí · 2024 · Computers in Biology and Medicine
- The Effect of Phosphoserine-Containing Membranes on Electrostatic Fields at the Protein–Protein Interface Measured through Vibrational Stark Effect SpectroscopyJackson C. Fink, Lauren J. Webb · 2025 · Biochemistry
- In silico analysis of wild-type and mutant KRASFrengki Frengki, Deddi Prima Putra, Fatma Sriwahyuni, Daan Khambri, Henni Vanda · 2019 · Pharmaciana
- Immediate and Selective Control of Protein Abundance Using the dTAG SystemBehnam Nabet, Nathanael S. Gray · 2020 · Royal Society of Chemistry eBooks
- New Avenue to Inhibit Ras SignalingXosé R. Bustelo · 2014 · Chemistry & Biology
- Divide and conquerMatthew T. Holderfield, Deborah K. Morrison · 2016 · Nature Chemical Biology
- Exploring binding modes of the selected inhibitors to phosphodiesterase delta by all-atom molecular dynamics simulations and free energy calculationsHui Zhong, Yanjun Zhang, Xiaobin Shan · 2018 · Journal of Biomolecular Structure and Dynamics
- Molecular mechanism of the association and dissociation of Deltarasin from the heterodimeric KRas4B‐PDEδ complexMartiniano Bello, José Correa‐Basurto, Miguel Angel Vargas · 2019 · Biopolymers
- Fully Processed Recombinant KRAS4b: Isolating and Characterizing the Farnesylated and Methylated ProteinConstance Agamasu, Peter H. Frank, Shelley C. Perkins, Timothy J. Waybright, Simon A. J. Messing, William Gillette, Andrew G. Stephen · 2020 · Journal of Visualized Experiments
- Regulation of ARL2 in colorectal cancer cell proliferation and tumorigenicity, and its negative association with AXLXunlei Pang, Yanhong Wang, Bei Miao, Sujuan Fei, Weichang Chen · 2021 · Oncology Letters
- The frequency of somatic mutations in cancer predicts the phenotypic relevance of germline mutationsE. Draetta, D. Lazarević, P. Provero, Davide Cittaro · 2023 · Frontiers in Genetics
- Extracellular Signal-Regulated Kinase (ERK1 and ERK2) InhibitorsAhmed A. Samatar · 2016 · Elsevier eBooks
- The Effective Targeting of KRASG12C ElusivenessElena Élez, Josep M. Tabernero · 2020 · Cancer Cell
- Absolute Quantitation of GTPase Protein AbundanceFiona E. Hood, Yasmina M. E. Sahraoui, Rosalind E. Jenkins, Ian A. Prior · 2021 · Methods in molecular biology
- A computational panel of pathological RAS mutants with implications for personalized medicine and genetic medicineChelsey Kenney, Edward C. Stites · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
- Developing Small Molecules that Inhibit K-Ras/GTP Binding Based on New Affinity MeasurementsLuca Carta, Rebecca Hutcheson, Simon A. Davis, Michael J. Rudolph, Charles H. Reynolds, Matthias Quick, Theresa M. Williams, Michael Schmertzler, Yaron R. Hadari · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Exploiting KRAS-Driven Ferroaddiction in Cancer Through Ferrous Iron-Activatable Drug Conjugates (FeADC)Honglin Jiang, Ryan K. Muir, Ryan L. Gonciarz, Adam B. Olshen, Iwei Yeh, Byron C. Hann, Ning Zhao, Yung-Hua Wang, Spencer C. Behr, Michael J. Evans et al. · 2020 · SSRN Electronic Journal
- Multiplexed identification of RAS paralog imbalance as a driver of lung cancer growthRui Tang, Emily G. Shuldiner, Marcus R. Kelly, Christopher W. Murray, Jess D. Hebert, Laura Andrejka, Min K. Tsai, Nicholas W. Hughes, Mitchell I. Parker, Hongchen Cai et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Potency and selectivity of a novel pan-RAS inhibitor in 3D bioprinted organoid tumor modelsDaniela Farias de Nóbrega, Logan C. Eiler, Parmanand Ahirwar, Urvi P. Rawal, Chelsea L. Crawford, Donald J. Buchsbaum, Adam B. Keeton, Yulia Y. Maxuitenko, Xi Chen, Gary Anthony Piazza et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Biophysical and Biochemical Characterization of Structurally Diverse Small Molecule Hits for KRAS InhibitionCynthia V. Pagba, Amit Kumar Gupta, K. M. Dilsha, Parisa Sadrpour, Jacob L. Jakubec, Priyanka Prakash, Dharini van der Hoeven, Kwang‐Jin Cho, Scott R. Gilbertson, Alemayehu Abebe Gorfe · 2024 · ChemBioChem
- Exploring the Role of PROTACs for the Treatment of Breast CancerArzoo Singh Pannu, Ramesh K. Goyal, Shikha Goswami · 2024 · Springer eBooks
- Current Understanding on Impact of Kirsten Rat Sarcoma Viral Oncogene Mutation on Colorectal Cancer: A ReviewShampa Pakhira, Priya Samanta, Rituparna Ghosh, Mrinmoyee Mondal, Souradeep Biswas, Rupali Sarkar, Arijit Bhowmik, Prosenjit Saha, Subhadip Hajra · 2024 · Journal of Current Oncological Trends
- Unimolecular Micelle for MLN8237 Delivery to Target AURKA-RalA Crosstalk for Ras-Driven Tumor Suppression in Mice XenograftsKajal Singh, Shahidkhan Pathan, Mehak Malhotra, M. Jayakannan, Nagaraj Balasubramanian · 2025 · Biomacromolecules
- RAS Pathway Inhibitors Combined with Targeted Agents Are Active in Patient-Derived Spheroids with Oncogenic KRAS Variants from Multiple Cancer TypesZahra Davoudi, Thomas Steven Dexheimer, Nathan P. Coussens, Thomas E. Silvers, Raymond G. Fox, Samantha B. Kemp, Poorva Juneja, Joel Morris, Melinda G. Hollingshead, Naoko Takebe et al. · 2025 · Cancer Research Communications
- Integrated methylome analysis identifies an epigenetically silenced tumor suppressor RASA4 in small cell lung cancerMeng Fu, Qizhi Zhu, Jian Qi, Xiaopeng Zhang, Zhipeng Wang, Jialiang Wang, Xiang Huang, Zongtao Hu, Wei Wang, Bo Hong et al. · 2025 · Communications Biology
- Systems-level consequences of low RAF abundance for EGFR-ERK signalingSung Hyun Lee, Paul J. Myers, Max C. Mendrzycki, Kevin Brown, Leslie M. Loew, Alexander D. Sorkin, Matthew J. Lazzara · 2026 · Biophysical Journal
- KRAS4a and KRAS4b show distinct lipid-dependent regulation of RAS-RAF membrane dynamicsKonstantia Georgouli, Jeremy O. B. Tempkin, Liam G. Stanton, Tomas Oppelstrup, Rebika Shrestha, Timothy S. Carpenter, Fikret Aydin, Xiaohua Zhang, Harsh Bhatia, Yue Yang et al. · 2026 · Journal of Biological Chemistry
- Disulfide tethering reveals cryptic pockets in oncogenic KRASTrent E. Balius, Marcin D. Dyba, Vandana Kumari, J. L. Denson, Ming Yi, Alok Kumar Sharma, Priyanka Prakash, Emily O. Alberico, Simon A. J. Messing, Vanessa E. Wall et al. · 2026 · Communications Chemistry
- A ternary association of KRas, EphA2, and integrins controls PDAC cell behaviorMahak Fatima, Nasir Haider, Stuart A. Cain, Bipul R. Acharya, Megan R. Chastney, Junzhe Zha, Matt Jones, Stacey Warwood, David Knight, Derek A O'Reilly et al. · 2026 · Journal of Biological Chemistry
- Changes in the transcriptome and synthetic lethal dependencies following KRAS mutant expression reveal profound tissue specificityTimothy D. Martin, Mei Yuk Choi, Julia C. McBride, Stephen Joseph Elledge · 2026 · Proceedings of the National Academy of Sciences
- Glutamate E15 and E171 are Hotspots in p60TRP-Related CancerArne Kutzner, Klaus Heese · 2016 · Cancer Investigation
- Mechanisms of l-Arginine-Auxotrophic Response and Their Cancer Therapeutic ImplicationsWen-Bin Tsai, Yan Long, Niramol Savaraj, Lynn G. Feun, Macus Tien Kuo · 2016 · Springer eBooks