Dragging Ras Back in the Ring
Cited by (801)
Items 201–300 of 801
- Machine Learning-Driven Multiscale Modeling: Bridging the Scales with a Next-Generation Simulation InfrastructureHelgi I. Ingólfsson, Harsh Bhatia, Fikret Aydin, Tomas Oppelstrup, César A. López, Liam G. Stanton, Timothy S. Carpenter, Sergio Wong, Francesco Di Natale, Xiaohua Zhang et al. · 2023 · Journal of Chemical Theory and Computation
- Endometrial Carcinoma: Specific Targeted PathwaysNúria Eritja, Andrée Yeramian, Bo‐Juen Chen, David Llobet‐Navàs, Eugenia Ortega, Eva Colás, Miguel Abal, Xavier Dolcet, Jaume Reventós, Xavier Matías‐Guiu · 2016 · Advances in experimental medicine and biology
- Total Chemical Synthesis and Folding of All- l and All- d Variants of Oncogenic KRas(G12V)Adam M. Levinson, John H. McGee, Andrew G. Roberts, Gardner S. Creech, Ting Wang, Michael T. Peterson, Ronald C. Hendrickson, Gregory L. Verdine, Samuel J. Danishefsky · 2017 · Journal of the American Chemical Society
- Malignant Transformation and Associated Biomarkers of Ovarian Endometriosis: A Narrative ReviewЛ.М. Михалева, A.I. Davydov, Пацап Ольга Игоревна, Михайленко Елизавета Вячеславовна, Vladimir Nikolaevich Nikolenko, Маргарита Е. Неганова, Sergey G. Klochkov, Siva G. Somasundaram, Cecil E. Kirkland, Gjumrakch Aliev · 2020 · Advances in Therapy
- AACR Cancer Progress Report 2015Jose M Baselga, Nina Bhardwaj, Lewis C. Cantley, Ronald P. DeMatteo, Raymond N. DuBois, Margaret Foti, Susan M. Gapstur, William C. Hahn, Lee J. Helman, Roy A. Jensen et al. · 2015 · Clinical Cancer Research
- USP39 Deubiquitinase Is Essential for KRAS Oncogene-driven CancerJulia M. Fraile, Eusebio Manchado, Amaia Lujambio, Vı́ctor Quesada, Diana Campos-Iglesias, Thomas R. Webb, Scott W. Lowe, Carlos López-Otı́n, José M.P. Freije · 2017 · Journal of Biological Chemistry
- Wild-type KRAS is a novel therapeutic target for melanoma contributing to primary and acquired resistance to BRAF inhibitionPeter Dietrich, Silke Kuphal, Thilo Spruß, Claus Hellerbrand, Anja‐Katrin Bosserhoff · 2017 · Oncogene
- A proteomic and phosphoproteomic landscape of KRAS mutant cancers identifies combination therapiesZhiwei Liu, Yingluo Liu, Lili Qian, Shangwen Jiang, Xiameng Gai, Shu Ye, Yuehong Chen, Xiaomin Wang, Linhui Zhai, Jun Qiang Xu et al. · 2021 · Molecular Cell
- Selective targeting of KRAS oncogenic alleles by CRISPR/Cas9 inhibits proliferation of cancer cellsLee, Wookjae, Lee, Joon Ho, Jun, Soyeong, Lee, Ji Hyun, Bang, Duhee · 2018 · Scientific Reports
- Prognosis of Lung Adenocarcinoma Patients With NTRK3 Mutations to Immune Checkpoint InhibitorsYuchun Niu, Anqi Lin, Peng Luo, Weiliang Zhu, Ting Wei, Ruixiang Tang, Linlang Guo, Jian Zhang · 2020 · Frontiers in Pharmacology
- Cellular Mechanism of Gene Mutations and Potential Therapeutic Targets in Ovarian CancerTao Guo, Xue Dong, Shanli Xie, Ling Zhang, Peibin Zeng, Lin Zhang · 2021 · Cancer Management and Research
- Integrated multi-omics characterization of KRAS mutant colorectal cancerWei Chong, Xingyu Zhu, Huicheng Ren, Chunshui Ye, Kang Xu, Zhe Wang, Shengtao Jia, Liang Shang, Leping Li, Hao Chen · 2022 · Theranostics
- RASAL2 down-regulation in ovarian cancer promotes epithelial-mesenchymal transition and metastasisYu-Ting Huang, Meng Zhao, Haixu Xu, Ke Wang, Zheng Fu, Yuan Jiang, Zhi Yao · 2014 · Oncotarget
- T Cell Recognition of Tumor Neoantigens and Insights Into T Cell ImmunotherapyMalcolm J. W. Sim, Peter D. Sun · 2022 · Frontiers in Immunology
- Molecular Pathways: Targeting RAC–p21-Activated Serine–Threonine Kinase Signaling in RAS-Driven CancersNicole M. Baker, Hoi Yee Chow, Jonathan Chernoff, Channing J. Der · 2014 · Clinical Cancer Research
- Molecular Pathways: Targeting the Dependence of Mutant RAS Cancers on the DNA Damage ResponseElda Grabocka, Cosimo Commisso, Dafna Bar‐Sagi · 2014 · Clinical Cancer Research
- KRAS Switch Mutants D33E and A59G Crystallize in the State 1 ConformationJia Lu, Asim K. Bera, Sudershan Reddy Gondi, Kenneth D. Westover · 2017 · Biochemistry
- KRAS mutant lung cancer: progress thus far on an elusive therapeutic targetSaveri Bhattacharya, Mark A. Socinski, Timothy Francis Burns · 2015 · Clinical and Translational Medicine
- Probing the Conformational and Energy Landscapes of KRAS Membrane OrientationPriyanka Prakash, Alemayehu Abebe Gorfe · 2019 · The Journal of Physical Chemistry B
- Toward a More Precise Future for OncologyMurciano-Goroff, Yonina R., Taylor, Barry S., Hyman, David M., Schram, Alison M. · 2020 · Cancer Cell
- The structural basis for cancer treatment decisionsRuth Nussinov, Hyunbum Jang, Chung‐Jung Tsai · 2014 · Oncotarget
- Encorafenib in combination with binimetinib for unresectable or metastatic melanoma with BRAF mutationsClaudia Trojaniello, Lucia Festino, Vito Vanella, Paolo A. Ascierto · 2019 · Expert Review of Clinical Pharmacology
- Dual inhibition of the PI3K and MAPK pathways enhances nab-paclitaxel/gemcitabine chemotherapy response in preclinical models of pancreatic cancerNiranjan Awasthi, David Kronenberger, Alexis Stefaniak, Sazzad Hassan, Urs W. von Holzen, Margaret A. Schwarz, Roderich Egbert Schwarz · 2019 · Cancer Letters
- Conformational transformation of switch domains in GDP/K-Ras induced by G13 mutants: An investigation through Gaussian accelerated molecular dynamics simulations and principal component analysisJianzhong Chen, Lifei Wang, Wei Wang, Haibo Sun, Laixue Pang, Huayin Bao · 2021 · Computers in Biology and Medicine
- Pharmacological restoration of GTP hydrolysis by mutant RASAntonio Cuevas-Navarro, Yasin Pourfarjam, Feng Hu, Diego J. Rodriguez, Alberto Vides, Ben Sang, Shijie Fan, Yehuda Goldgur, Elisa de Stanchina, Piro Lito · 2024 · Nature
- Neuroblastoma RAS Viral Oncogene Homolog (NRAS) Is a Novel Prognostic Marker and Contributes to Sorafenib Resistance in Hepatocellular CarcinomaPeter Dietrich, Anne Gaza, Laura Wormser, VALERIE K. FRITZ, Claus Hellerbrand, Anja‐Katrin Bosserhoff · 2019 · Neoplasia
- Current Treatment of Juvenile Myelomonocytic LeukemiaChristina Mayerhofer, Charlotte Marie Niemeyer, Christian Flotho · 2021 · Journal of Clinical Medicine
- A KRAS GTPase K104Q Mutant Retains Downstream Signaling by Offsetting Defects in RegulationGuowei Yin, Samantha Kistler, Samuel D. George, Nora Kuhlmann, Leslie A. Garvey, Minh V. Huynh, Rachel Bagni, Michael Lammers, Channing J. Der, Sharon L. Campbell · 2017 · Journal of Biological Chemistry
- A Potent Isoprenylcysteine Carboxylmethyltransferase (ICMT) Inhibitor Improves Survival in Ras-Driven Acute Myeloid LeukemiaNagore I. Marín‐Ramos, Moisés Balabasquer, Francisco J. Ortega-Nogales, Iván R. Torrecillas, Ana Gil-Ordóñez, Beatriz Marcos‐Ramiro, Pedro Aguilar-Garrido, Ian Cushman, Antonio Romero, Francisco J. Medrano et al. · 2019 · Journal of Medicinal Chemistry
- Oncoprotein Inhibitor Rigosertib Loaded in ApoE-Targeted Smart Polymersomes Reveals High Safety and Potency against Human Glioblastoma in MiceHuazhen Qin, Yu Jiang, Jian Zhang, Chao Deng, Zhiyuan Zhong · 2019 · Molecular Pharmaceutics
- KRAS-dependent cancer cells promote survival by producing exosomes enriched in SurvivinWen-Hsuan Chang, Thuy‐Tien T. Nguyen, Chia‐Hsin Hsu, Kirsten L. Bryant, Hong Jin Kim, Haoqiang Ying, Jon W. Erickson, Channing J. Der, Richard A. Cerione, Marc A. Antonyak · 2021 · Cancer Letters
- BCL6 confers KRAS-mutant non–small-cell lung cancer resistance to BET inhibitorsJiawei Guo, Yanan Liu, Jing Lv, Bin Zou, Zhi Chen, Kun Li, Juanjuan Feng, Zhenyu Cai, Lai Wei, Mingyao Liu et al. · 2021 · Journal of Clinical Investigation
- Targeting KRAS mutant lung cancer: light at the end of the tunnelMatthias Drosten, Mariano Barbacid · 2021 · Molecular Oncology
- Engineering therapeutic proteins for cell entry: the natural approachSandrine Guillard, Ralph Minter, Ronald H. Jackson · 2015 · Trends in biotechnology
- Molecular Biomarkers of Pancreatic Intraepithelial Neoplasia and Their Implications in Early Diagnosis and Therapeutic Intervention of Pancreatic CancerJunli Guo, Keping Xie, Shaojiang Zheng · 2016 · International Journal of Biological Sciences
- Studying protein–protein interactions: progress, pitfalls and solutionsSheri L. Hayes, Beatrice Malacrida, Maeve Bailey‐Whyte, Patrick A. Kiely · 2016 · Biochemical Society Transactions
- Mutated RAS: Targeting the “Untargetable” with T CellsPraveen D. Chatani, James Chih‐Hsin Yang · 2019 · Clinical Cancer Research
- Deregulation of the Ras-Erk Signaling Axis Modulates the Enhancer LandscapeBehnam Nabet, Pilib Ó Broin, Jaime M. Reyes, Kevin R. Shieh, Charles Y. Lin, Christine Will, Relja Popovic, Teresa Ezponda, James E. Bradner, Aaron A. Golden et al. · 2015 · Cell Reports
- RAC1 and MelanomaRuth Halaban · 2014 · Clinical Therapeutics
- KRAS Engages AGO2 to Enhance Cellular TransformationSunita Shankar, Sethuramasundaram Pitchiaya, Rohit Malik, Vishal Kothari, Yasuyuki Hosono, Anastasia K. Yocum, Harika Gundlapalli, Yasmine N. White, Ari J. Firestone, Xuhong Cao et al. · 2016 · Cell Reports
- Isoprenylcysteine carboxylmethyltransferase is critical for malignant transformation and tumor maintenance by all RAS isoformsH Y Lau, Jingyi Tang, Patrick J. Casey, Mei Wang · 2017 · Oncogene
- Blocking Ras inhibition as an antitumor strategyNagore I. Marín‐Ramos, Silvia Ortega‐Gutiérrez, María Luz López-Rodríguez · 2018 · Seminars in Cancer Biology
- KRAS targeting antibody synergizes anti-cancer activity of gemcitabine against pancreatic cancerYeo Wool Kang, Ji Eun Lee, Kyung Hee Jung, Mi Kwon Son, Seungmin Shin, Soo‐Jeong Kim, Zhenghuan Fang, HONG HUA YAN, Jung Hee Park, Boreum Han et al. · 2018 · Cancer Letters
- RAS genes in colorectal carcinoma: pathogenesis, testing guidelines and treatment implicationsOmer Abdelaziz Mohammed Saeed, Antonio Lopez-beltran B, Kurt W. Fisher, Marina Scarpelli, Rodolfo Montironi, Alessia Cimadamore, Francesco Massari, Matteo Santoni, Liang Cheng C · 2018 · Journal of Clinical Pathology
- Nootkatone, an AMPK activator derived from grapefruit, inhibits KRAS downstream pathway and sensitizes non-small-cell lung cancer A549 cells to adriamycinLe Van Manh Hung, Jeong Yong Moon, Jiyeon Ryu, Somi Kim Cho · 2019 · Phytomedicine
- The Methods Employed in Mass Spectrometric Analysis of Posttranslational Modifications (PTMs) and Protein–Protein Interactions (PPIs)Rama Yakubu, Edward Nieves, Louis M. Weiss · 2019 · Advances in experimental medicine and biology
- An essential role for Argonaute 2 in EGFR-KRAS signaling in pancreatic cancer developmentSunita Shankar, Jean Ching-Yi Tien, Ronald F. Siebenaler, Seema Chugh, Vijaya L. Dommeti, Sylvia Zelenka-Wang, Jessica J. Waninger, Kristin M. Juckette, Alice Xu, Xiao-Ming Wang et al. · 2020 · Nature Communications
- Allelic Ratio of KRAS Mutations in Pancreatic CancerJochen K. Lennerz, Albrecht Stenzinger · 2015 · The Oncologist
- Induction of early growth response gene 1 (EGR1) by endoplasmic reticulum stress is mediated by the extracellular regulated kinase (ERK) arm of the MAPK pathwaysJixiu Shan, Elizabeth E. Dudenhausen, Michael S. Kilberg · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Targeted therapy for pancreatic ductal adenocarcinoma: Mechanisms and clinical studyHeng‐Chung Kung, Jun Yu · 2023 · MedComm
- Non-canonical integrin signaling activates EGFR and RAS-MAPK-ERK signaling in small cell lung cancerKarla Rubio, Addi J. Romero‐Olmedo, Pouya Sarvari, Guruprasadh Swaminathan, Vikas Ranvir, Diana G. Rogel-Ayala, Julio Cordero, Stefan Günther, Aditi Mehta, Birgit Bassaly et al. · 2023 · Theranostics
- Intrinsic K-Ras dynamics: A novel molecular dynamics data analysis method shows causality between residue pair motionsSezen Vatansever, Zeynep Hulya Gumus, Burak Erman · 2016 · Scientific Reports
- The role of KRAS splice variants in cancer biologyCristina Nuevo‐Tapioles, Mark R. Philips · 2022 · Frontiers in Cell and Developmental Biology
- Antitumor Properties of RAF709, a Highly Selective and Potent Inhibitor of RAF Kinase Dimers, in Tumors Driven by Mutant RAS or BRAFWenlin Shao, Yuji M. Mishina, Yunjiang Feng, Giordano Caponigro, Vesselina G. Cooke, Stacy Rivera, Yingyun Wang, Fang Shen, Joshua M. Korn, Lesley A. Mathews Griner et al. · 2018 · Cancer Research
- Combined Proteomic and Genetic Interaction Mapping Reveals New RAS Effector Pathways and SusceptibilitiesMarcus R. Kelly, Kaja Kostyrko, Kyuho Han, Nancie A. Mooney, Edwin E. Jeng, Kaitlyn Spees, Phuong Dinh, Keene L. Abbott, Dana M. Gwinn, Alejandro Sweet-Cordero et al. · 2020 · Cancer Discovery
- Efforts to Develop KRAS InhibitorsHolderfield, Matthew · 2018 · Cold Spring Harbor Perspectives in Medicine
- K-RAS mutations indicating primary resistance to crizotinib in ALK -rearranged adenocarcinomas of the lung: Report of two cases and review of the literatureMaria Cecilia Mengoli, Fausto Barbieri, Federica Bertolini, Marcello Tiseo, Giulio Rossi · 2016 · Lung Cancer
- Structural fingerprints, interactions, and signaling networks of RAS family proteins beyond RAS isoformsSaeideh Nakhaei‐Rad, Fereshteh Haghighi, Parivash Nouri, Soheila Rezaei Adariani, Jana Lissy, Neda S. Kazemein Jasemi, Radovan Dvorský, Mohammad Reza Ahmadian · 2018 · Critical Reviews in Biochemistry and Molecular Biology
- PIP2 Influences the Conformational Dynamics of Membrane-Bound KRAS4bMark A. McLean, Andrew G. Stephen, Stephen G. Sligar · 2019 · Biochemistry
- Aurora A kinase and its activator TPX2 are potential therapeutic targets in KRAS-induced pancreatic cancerSandro Mascena Gomes-Filho, Edmilson Ozorio dos Santos, Ester Risério Matos Bertoldi, Luiza Coimbra Scalabrini, Vitor Heidrich, Bianca Dazzani, Elena Levantini, Eduardo M. R. Reis, Daniela S. Daniela Sanchez Bassères · 2020 · Cellular Oncology
- Targeting mutated GTPase KRAS in tumor therapiesGuangjin Fan, Linlin Lou, Zhendong Song, Xiaolei Zhang, Xiao‐Feng Xiong · 2021 · European Journal of Medicinal Chemistry
- The role of wild-type RAS in oncogenic RAS transformationSheffels, Erin, Kortum, Robert L. · 2021 · Genes
- A MEK/PI3K/HDAC inhibitor combination therapy for KRAS mutant pancreatic cancer cellsIrene Ischenko, Oleksi Petrenko, Michael J. Hayman · 2015 · Oncotarget
- SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation statusHa Yong Song, Marco Biancucci, Hong-Jun Kang, Carol O'Callaghan, Seong‐Hoon Park, Daniel R. Principe, Haiyan Jiang, Yufan Yan, K.J.F. Satchell, Kirtee Raparia et al. · 2016 · Oncotarget
- In-silico design of peptide inhibitors of K-Ras target in cancer diseaseMehreen Ghufran, Ashfaq Ur Rehman, Masaud Shah, Muhammad Ayaz, Ho Leung Ng, Abdul Wadood · 2019 · Journal of Biomolecular Structure and Dynamics
- Small molecular inhibitors for KRAS-mutant cancersXuan Wu, Wenping Song, Cheng Cheng, Ziyang Liu, Xiang Li, Yu Cui, Yao Gao, Li Ding · 2023 · Frontiers in Immunology
- The geroprotectors trametinib and rapamycin combine additively to extend mouse healthspan and lifespanLisonia Gkioni, Tobias Nespital, Maarouf Baghdadi, Carolina Monzó, Jitin Bali, Taim Nassr, Anna Lena Cremer, Andreas Beyer, Joris Deelen, Heiko Backes et al. · 2025 · Nature Aging
- Properties of FDA-approved small molecule protein kinase inhibitors: A 2026 updateRobert Jr. Roskoski · 2026 · Pharmacological Research
- Genomic characterization of patient-derived xenograft models established from fine needle aspirate biopsies of a primary pancreatic ductal adenocarcinoma and from patient-matched metastatic sitesRobert J. Allaway, Dawn A. Fischer, Francine Blumental De Abreu, Timothy B. Gardner, Stuart R. Gordon, Richard J. Barth, Thomas A. Colacchio, Matthew D. Wood, Balint Z Kacsoh, Stephanie J. Bouley et al. · 2016 · Oncotarget
- How to Target Activated Ras Proteins: Direct Inhibition vs. Induced MislocalizationEthan J. Brock, Kyungmin Ji, John J. Reiners, Raymond R. Mattingly · 2015 · Mini-Reviews in Medicinal Chemistry
- Farnesyltransferase-Mediated Delivery of a Covalent Inhibitor Overcomes Alternative Prenylation to Mislocalize K-RasChris J. Novotny, Gregory L. Hamilton, Frank P. McCormick, Kevan M. Shokat · 2017 · ACS Chemical Biology
- IκB Kinase α Is Required for Development and Progression of KRAS -Mutant Lung AdenocarcinomaMalamati Vreka, Ioannis Lilis, Maria Papageorgopoulou, Georgia A. Giotopoulou, Marina Lianou, Ioanna Giopanou, Nikolaos I. Kanellakis, Μάγδα Σπέλλα, Theodora Agalioti, Vasileios Armenis et al. · 2018 · Cancer Research
- Identification of a new inhibitor of KRAS‐PDEδ interaction targeting KRAS mutant nonsmall cell lung cancerLeung, Elaine Lai‐Han, Luo, Lian Xiang, Li, Ying, Liu, Zhong‐Qiu, Li, Lan Lan, Shi, Dan Feng, Xie, Ying, Huang, Min, Lu, Lin Lin, Duan, Fu Gang et al. · 2019 · International Journal of Cancer
- Dimethyl fumarate is highly cytotoxic in KRAS mutated cancer cells but spares non-tumorigenic cellsNathaniel Edward Bennett Saidu, Marie Bretagne, Audrey Mansuet‐Lupo, Pierre‐Alexandre Just, Karen Leroy, Olivier Cerles, Sandrine Chouzenoux, Carole Nicco, Diane Damotte, Marco Alifano et al. · 2018 · Oncotarget
- The Mir181ab1 cluster promotes KRAS-driven oncogenesis and progression in lung and pancreasKarmele Valencia, Oihane Erice, Kaja Kostyrko, Simone Hausmann, Elizabeth Guruceaga, Anuradha Tathireddy, Natasha Mahealani Flores, Leanne C. Sayles, Alex Gia Lee, Rita Fragoso et al. · 2019 · Journal of Clinical Investigation
- Paradoxical effects of statins on endothelial and cancer cells: the impact of concentrationsYasin Ahmadi, Javad Khalili Fard, Dlzar Dlshad Ghafoor, Ali Hussein Eid, Amirhossein Sahebkar · 2023 · Cancer Cell International
- MYC and RAF: Key Effectors in Cellular Signaling and Major Drivers in Human CancerEduard Stefan, Klaus Bister · 2017 · Current topics in microbiology and immunology
- PP6 Disruption Synergizes with Oncogenic Ras to Promote JNK-Dependent Tumor Growth and InvasionXianjue Ma, Jinyu Lu, Yongli Dong, Daming Li, Juan Nicolas Malagón, Tian Xu · 2017 · Cell Reports
- Drug library screen reveals benzimidazole derivatives as selective cytotoxic agents for KRAS-mutant lung cancerIwao Shimomura, Akira Yokoi, Isaku Kohama, Minami Kumazaki, Yuji Tada, Koichiro Tatsumi, Takahiro Ochiya, Yusuke Yamamoto · 2019 · Cancer Letters
- The prevalence and prognostic value of KRAS co‐mutation subtypes in Chinese advanced non‐small cell lung cancer patientsDongjing Cai, Chengping Hu, Li Li, S. Deng, Jing Yang, Han Han‐Zhang, Min Li · 2019 · Cancer Medicine
- Intrinsic GTPase activity of K-RAS monitored by native mass spectrometryMoghadamchargari, Zahra, Huddleston, Jamison, Shirzadeh, Mehdi, Zheng, Xueyun, Clemmer, David E., M. Raushel, Frank, Russell, David H., Laganowsky, Arthur · 2019 · Biochemistry
- Molecular assemblies of the catalytic domain of SOS with KRas and oncogenic mutantsMoghadamchargari, Zahra, Shirzadeh, Mehdi, Liu, Chang, Schrecke, Samantha, Packianathan, Charles, Russell, David H., Zhao, Minglei, Laganowsky, Arthur · 2021 · Proceedings of the National Academy of Sciences
- Parameterization of Palmitoylated Cysteine, Farnesylated Cysteine, Geranylgeranylated Cysteine, and Myristoylated Glycine for the Martini Force FieldYoav Atsmon‐Raz, D. Peter Tieleman · 2017 · The Journal of Physical Chemistry B
- Genomic Characteristics of Invasive Mucinous Adenocarcinomas of the Lung and Potential Therapeutic Targets of B7-H3Takahiro Nakagomi, Taichiro Goto, Yosuke Hirotsu, Daichi Shikata, Yujiro Yokoyama, Rumi Higuchi, Sotaro Otake, Kenji Amemiya, Toshio Oyama, Hitoshi Mochizuki et al. · 2018 · Cancers
- Differential Outcomes in Codon 12/13 and Codon 61 NRAS -Mutated Cancers in the Phase II NCI-MATCH Trial of Binimetinib in Patients with NRAS -Mutated TumorsJames M. Cleary, Victoria Wang, Rebecca Suk Heist, Scott Kopetz, Edith Peterson Mitchell, James A. Zwiebel, Kevin S. Kapner, Helen X. Chen, Shuli Li, Robert J. Gray et al. · 2021 · Clinical Cancer Research
- Blockade of mutant RAS oncogenic signaling with a special emphasis on KRASRobert Jr. Roskoski · 2021 · Pharmacological Research
- ARL2 overexpression inhibits glioma proliferation and tumorigenicity via down-regulating AXLYulin Wang, Gefei Guan, Wen Cheng, Yang Jiang, Fengping Shan, Anhua Wu, Peng Cheng, Zongze Guo · 2018 · BMC Cancer
- Functional link between plasma membrane spatiotemporal dynamics, cancer biology, and dietary membrane-altering agentsAlfredo Erazo‐Oliveras, Natividad Roberto Fuentes, Rachel C. Wright, Robert S. Chapkin · 2018 · Cancer and Metastasis Reviews
- p21-activated kinase signalling in pancreatic cancer: New insights into tumour biology and immune modulationKai Wang, Graham S. Baldwin, Mehrdad Nikfarjam, Hong Zhen He · 2018 · World Journal of Gastroenterology
- Approaches to inhibiting oncogenic K-RasAlemayehu Abebe Gorfe, Kwang‐Jin Cho · 2019 · Small GTPases
- Prognostic and therapeutic impact of the KRAS G12C mutation in colorectal cancerLindor Qunaj, Michael S. May, Alfred I. Neugut, Benjamin O. Herzberg · 2023 · Frontiers in Oncology
- Mutational Analysis of Ionizing Radiation Induced NeoplasmsAmy L. Sherborne, Philip R. Davidson, Katharine Yu, Alice Nakamura, Mamunur Rashid, Jean L. Nakamura · 2015 · Cell Reports
- AMPK Promotes Aberrant PGC1β Expression To Support Human Colon Tumor Cell SurvivalKurt W. Fisher, Binita Das, Hyun Seok Kim, Beth K. Neilsen, Drew Gehring, Deandra R. Smith, Diane L. Costanzo-Garvey, Mario R. Fernandez, Michael G. Brattain, David L. Kelly et al. · 2015 · Molecular and Cellular Biology
- EGFR phosphorylates FAM129B to promote Ras activationHaitao Ji, Jong-Ho Lee, Yugang Wang, Yilin Pang, Tao Zhang, Yan Xia, Lianjin Zhong, Jianxin Lyu, Zhimin Lu · 2015 · Proceedings of the National Academy of Sciences
- NRAS destines tumor cells to the lungsAnastasios D. Giannou, Antonia Marazioti, Nikolaos I. Kanellakis, Ioanna Giopanou, Ioannis Lilis, Dimitra E. Zazara, Giannoula Ntaliarda, Danai Kati, Vasileios Armenis, Georgia A. Giotopoulou et al. · 2017 · EMBO Molecular Medicine
- Myeloid-derived interleukin-1β drives oncogenic KRAS-NF-κΒ addiction in malignant pleural effusionAntonia Marazioti, Ioannis Lilis, Malamati Vreka, Hara Apostolopoulou, Argyro Kalogeropoulou, Ioanna Giopanou, Georgia A. Giotopoulou, Anthi C. Krontira, Marianthi P. Iliopoulou, Nikolaos I. Kanellakis et al. · 2018 · Nature Communications
- Analysis of the miRNA Expression Profiles in the Zearalenone-Exposed TM3 Leydig Cell LineMingyang Wang, Weiwei Wu, Lin Li, Jianbin He, Sheng Huang, Si Chen, Jia Chen, Miao Long, Shuhua Yang, Peng Li · 2019 · International Journal of Molecular Sciences
- Combined effects of PLK1 and RAS in hepatocellular carcinoma reveal rigosertib as promising novel therapeutic “dual-hit” optionPeter Dietrich, K Freese, Abdo Mahli, Wolfgang Erwin Thasler, Claus Hellerbrand, Anja‐Katrin Bosserhoff · 2017 · Oncotarget
- Synthetic Lethality of a Novel Small Molecule Against Mutant KRAS-Expressing Cancer Cells Involves AKT-Dependent ROS ProductionKartini Bte Iskandar, Majidah Rezlan, Sanjiv Kumar Yadav, Chuan Han Jonathan Foo, Gautam Sethi, Qiang Yu, Gregory Lucien Bellot, Shazib Pervaiz · 2015 · Antioxidants and Redox Signaling
- Regulation of large and small G proteins by ubiquitinationHenrik Gunnar Dohlman, Sharon L. Campbell · 2019 · Journal of Biological Chemistry