The DOI matches its Crossref record; 25 of the 25 references it cites were found in a registry or an index.
The Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE): Method and design considerations
Open accessAbstract
Background Due to the concentration of individuals at-risk for suicide, an emergency department visit represents an opportune time for suicide risk screening and intervention.Purpose The Emergency Department Safety Assessment and Follow-up Evaluation (ED-SAFE) uses a quasi-experimental, interrupted time series design to evaluate whether (1) a practical approach to universally screening ED patients for suicide risk leads to improved detection of suicide risk and (2) a multi-component intervention delivered during and after the ED visit improves suicide-related outcomes.Methods This paper summarizes the ED-SAFE's study design and methods within the context of considerations relevant to effectiveness research in suicide prevention and pertinent human participants concerns. 1440 suicidal individuals, from 8 general ED's nationally will be enrolled during three sequential phases of data collection (480 individuals/phase): (1) Treatment as Usual; (2) Universal Screening; and (3) Intervention. Data from the three phases will inform two separate evaluations: Screening Outcome (Phases 1 and 2) and Intervention (Phases 2 and 3). Individuals will be followed for 12 months. The primary study outcome is a composite reflecting completed suicide, attempted suicide, aborted or interrupted attempts, and implementation of rescue procedures during an outcome assessment.Conclusions While 'classic' randomized control trials (RCT) are typically selected over quasi-experimental designs, ethical and methodological issues may make an RCT a poor fit for complex interventions in an applied setting, such as the ED. ED-SAFE represents an innovative approach to examining the complex public health issue of suicide prevention through a multi-phase, quasi-experimental design embedded in 'real world' clinical settings.
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“using common continuous quality improvement (CQI) strategies, it was feasible to increase suicide screening to reach, on average, 85% of the adult ED population across eight diverse EDs”
From Emergency department safety assessment and follow-up evaluation 2: an implementation trial to improve suicide prevention. (2020) · cites this paper as [9]
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“) have found that nineteen percent of suicide attempters treated in the ED will re-attempt within the 6 months after the visit [4], and 39% of completed suicides are by people who had been seen in an ED within the year before their death [5].”
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- Boudreaux, 2005, Validation of depression and bipolar disorder screening among emergency department patients, Ann Behav Med, 29
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Items 101–113 of 113
Suicide Prevention in Emergency Department Settings
Yonemoto, N. (2022) · Springer eBooks · doi:10.1007/978-3-030-42003-1_64
A gestão de emergências psiquiátricas em situações de calamidade pública
Baldaçara, L., da Silva, A. G., Pereira, L. A., Malloy‐Diniz, L. F., & Tung, T. C. (2024) · Debates em Psiquiatria · doi:10.25118/2763-9037.2024.v14.1239
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Management of acute psychiatric emergencies
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Özkıyım Davranışlarında Kısa Acil Girişimler ve Acil Psikoterapi Yaklaşımları
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Rabasco, A., Choi, J., Ladis, I., Arias, S. A., Weinstock, L. M., Miller, I., Boudreaux, E. D., Camargo, C. A., & Gaudiano, B. A. (2026) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2026.03.040
Self-citationRabasco, A., Browne, J., Kunicki, Z. J., Benz, M. B., Arias, S. A., Weinstock, L. M., Miller, I. W., Boudreaux, E. D., Camargo, C. A., & Gaudiano, B. A. (2026) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.70093
Self-citationSuicide risk among emergency care patients: Exploring incidental risk detection during routine care
Boudreaux, E. D., Ardelean, A. J., Davis-Martin, R. E., Kelly, L. M., Betz, M. E., Arias, S. A., Boyle, K. L., Camargo, C. A., Caterino, J. M., Eastin, C. D., et al. (2026) · General Hospital Psychiatry · doi:10.1016/j.genhosppsych.2026.05.011
Self-citationRisk Rulers for Rapid Screening and Detection of Suicide Risk in Acute Care
Boudreaux, E. D., Lee, H. S., Larkin, C., Davis-Martin, R. E., Beiser, D. G., & Gibbons, R. D. (2026) · Suicide and Life-Threatening Behavior · doi:10.1111/sltb.70112
Self-citationImplementing psychological care in emergency departments for suicide prevention
Luo, F., Wu, W.-Y., Wang, J., Fang, K.-J., Xing, H.-Y., & Yan, J. (2026) · World Journal of Psychiatry · doi:10.5498/wjp.116382
Marques, V., Boudreaux, E. D., Miller, I. W., Camargo, C. A., & Arias, S. A. (2026) · Archives of Suicide Research · doi:10.1080/13811118.2026.2724122
Self-citationGiustini, M., Pitidis, A., Fazio, C., Alves, T., Fian, T., Valkenberg, H., Nijman, S. T. M., Papadakaki, M., & Carannante, A. (2026) · Frontiers in Digital Health · doi:10.3389/fdgth.2026.1964834
Petrik, M. L. (2014) · e-Publications@Marquette (Marquette University)
Metadata
- Authors
- Boudreaux, E. D., Miller, I., Goldstein, A. B., Sullivan, A. F., Allen, M. H., Manton, A. P., Arias, S. A., & Camargo, C. A.
- Affiliations
- University of Massachusetts Chan Medical School (US)
- Butler Hospital (US)
- National Institutes of Health (US)
- Massachusetts General Hospital (US)
- VA Rocky Mountain Network (US)
- Cape Cod Hospital (US)
- Corresponding author
- Boudreaux, Edwin D.
- Venue
- Contemporary Clinical Trials
- Publisher
- Elsevier BV
- Published
- 2013-09
- Volume
- 36
- Issue
- 1
- Pages
- 14-24
- ISSN
- 1551-7144 (ISSN-L)
- PMC
- PMC3979300
- OpenAlex
- W2024562192
- Cited by
- 113
- References
- 25
- Citations by year
- 2026: 7 · 2025: 12 · 2024: 10 · 2023: 10 · 2022: 5 · 2021: 5 · 2020: 11 · 2019: 9 · 2018: 10 · 2017: 15 · 2016: 8 · 2015: 6 · 2014: 5
- FWCI
- 7.05
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Contemporary Clinical Trials (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- The Journal of the American Medical Association (JAMA) Network (American Medical Association) (submittedVersion)
- Funders
- National Institute of Mental Health (U01MH088278)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Suicide and Self-Harm Studies
- Health Sciences › Medicine › Emergency Medicine › Emergency and Acute Care Studies
- Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
- Keywords
- suicide risk screening, emergency department, universal screening, suicide prevention, complex interventions, interrupted time series design, quasi-experimental design, suicide attempts, suicide mortality, follow-up evaluation
- MeSH terms
- Suicide Prevention, Mental Disorders, Emergency Service, Hospital, Health Services Research, Humans, Mass Screening, Mental Health, Outcome and Process Assessment, Health Care, Research Design, Suicide
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