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Cited by 16Smoking Behavior and CessationHealth Policy Implementation ScienceSubstance Abuse Treatment and Outcomes

Nicotine replacement therapy sampling via primary care: Methods from a pragmatic cluster randomized clinical trial

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Dahne, Jennifer, Wahlquist, Amy E., Boatright, Amy S., Garrett-Mayer, Elizabeth, Fleming, Douglas O., Davis, Robert, Egan, Brent, Carpenter, Matthew J.·2018·Contemporary Clinical Trials
DOI 10.1016/j.cct.2018.07.008PMC PMC6133738
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Abstract

Background Primary care is the most important point of healthcare contact for smokers. Brief physician advice to quit, based on the 5As/AAR model, offers some efficacy but is inconsistently administered and has limited population impact. Nicotine replacement therapy (NRT) sampling, defined as provision of a brief NRT starter kit, when added to the 5As/AAR, is well-suited to primary care because it is simple, brief, and can be provided to all smokers. This article describes the design and methods of an ongoing comparative effectiveness trial testing standard care vs. standard care + NRT sampling within primary care.Methods Smokers were recruited directly from primary care practices between July 2014 and December 2017 within an established network of South Carolina clinics. Interventions were delivered randomly by clinic personnel, and phone-based follow-ups were centrally coordinated by research staff to track outcomes through six months post-intervention. Primary study aims are to examine the impact of NRT sampling on smoking, inclusive of cessation, quit attempts, and uptake of evidence-based treatment.Results Twenty-two clinics were recruited. Across clinics, patient census ranged from 985 to 10,957 and number of providers ranged from 1 to 63. Average patient age across clinics was 52.9 years and smoking prevalence across ranged from 10.6% to 28.5%.Conclusion Improving the effectiveness and reach of brief interventions within primary care could have a considerable impact on population quit rates. We consider the advantages and disadvantages of key methodological decisions relevant to the design of future primary care-based cessation trials.

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  1. [10]Blumenthal DS, Barriers to the provision of smoking cessation services reported by clinicians in underserved communities, J. Am. Board Fam. Med 20 (2007) 272– 279. 17478660
  2. [35]Hall SM, Humfleet GL, Munoz RF, Reus VI, Prochaska JJ, Robbins JA, Using extended cogntive behavioral treatment and medication to treat dependent smokers, Am. J. Public Health 101 (2011) 2349– 2356. 21653904 PMC3222443

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Authors
Dahne, J., Wahlquist, A. E., Boatright, A. S., Garrett-Mayer, E., Fleming, D. O., Davis, R., Egan, B., & Carpenter, M. J.
Affiliations
  • Medical University of South Carolina (US)
  • University of Southern California (US)
  • University of South Carolina (US)
Corresponding author
  • Dahne, Jennifer
  • Carpenter, Matthew J.
ORCID
Venue
Contemporary Clinical Trials
Publisher
Elsevier BV
Published
2018-09
Volume
72
Pages
1-7
ISSN
1551-7144 (ISSN-L)
DOI
10.1016/j.cct.2018.07.008
PMC
PMC6133738
OpenAlex
W2883503269
Cited by
16
References
47
Citations by year
2025: 2 · 2024: 1 · 2023: 2 · 2022: 2 · 2021: 2 · 2020: 6 · 2017: 1
FWCI
1.38
Type
journal article
Language
en
Open access
Licence
Locations
  • Contemporary Clinical Trials (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
National Institute on Drug Abuse (K23DA045766, T32DA007288, R01DA021619)
Topics
  • Health Sciences › Medicine › Physiology › Smoking Behavior and Cessation
  • Health Sciences › Health Professions › General Health Professions › Health Policy Implementation Science
  • Health Sciences › Medicine › Epidemiology › Substance Abuse Treatment and Outcomes
Keywords
nicotine replacement therapy, smoking cessation, primary care, comparative effectiveness, quit attempts, smoking prevalence
MeSH terms
Humans, Primary Health Care, Smoking, Multicenter Studies as Topic, Smoking Cessation, Tobacco Use Cessation Devices, Pragmatic Clinical Trials as Topic

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