The DOI matches its Crossref record; 63 of the 64 references it cites were found in a registry or an index.
Evidence-Based Dentistry Update on Silver Diamine Fluoride
Open accessAbstract
This article reviews current evidence on the effectiveness of silver diamine fluoride (SDF) as a caries arresting and preventive agent. It provides clinical recommendations around SDF's appropriate use as part of a comprehensive caries management program. Systematic reviews confirm that SDF is effective for caries arrest on cavitated lesions in primary teeth and root caries in the elderly. It may also prevent new lesions. Application is easy, noninvasive, affordable, and safe. Although it stains the lesions dark as it arrests them, it provides clinicians with an additional tool for caries management when esthetics are not a primary concern.
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“For instance, SDF a non-invasive, cost-effective topical agent has been shown to arrest caries progression in primary teeth by up to 80%, making it particularly valuable for underserved populations and children with dental anxiety or special healthcare needs [7,8].”
From Minimally Invasive Techniques for Managing Dental Caries in Children: Efficacy, Applications, and Future Directions (2025) · cites this paper as [7]
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“Studies show that applying it twice a year can greatly lower the risk of cavities by keeping a high level of fluoride on teeth for a long time.7,8”
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Cites
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: the PRISMA statement
Moher, D., Liberati, A., Tetzlaff, J., Altman, D. G., & for the PRISMA Group (2009) · BMJ · doi:10.1136/bmj.b2535 · Cited by 83,823
Preferred reporting items for systematic reviews and meta-analyses: the PRISMA Statement.
(2009) · PubMed Central · Cited by 44,859
Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement
Moher, D., Liberati, A., Tetzlaff, J., & Altman, D. G. (2009) · Journal of Clinical Epidemiology · doi:10.1016/j.jclinepi.2009.06.005 · Cited by 19,575
The global increase in dental caries. A pending public health crisis.
Er, B., Garcı́a-Godoy, F., & Volpe, A. R. (2009) · PubMed · Cited by 730
Silver Diamine Fluoride: A Caries “Silver-Fluoride Bullet”
Rosenblatt, A., Stamford, T. C. M., & Niederman, R. (2009) · Journal of Dental Research · doi:10.1177/0022034508329406 · Cited by 546
Self-citationChu, C. H., Lo, E. C. M., & Lin, H. (2002) · Journal of Dental Research · doi:10.1177/0810767 · Cited by 477
UCSF Protocol for Caries Arrest Using Silver Diamine Fluoride: Rationale, Indications and Consent
Horst, J. A., Ellenikiotis, H., & Milgrom, P. L. (2016) · Journal of the California Dental Association · doi:10.1080/19424396.2016.12220962 · Cited by 426
Llodrá, J. C., Rodríguez, A., Ferrer, B., Pejoan, V. M., Ramos, T., & Morato, M. G. D. M. (2005) · Journal of Dental Research · doi:10.1177/154405910508400807 · Cited by 358
Effective use of fluorides for the prevention of dental caries in the 21st century: the WHO approach
Petersen, P. E., & Lennon, M. A. (2004) · Community Dentistry and Oral Epidemiology · doi:10.1111/j.1600-0528.2004.00175.x · Cited by 328
WHO Global Consultation on Public Health Intervention against Early Childhood Caries
Phantumvanit, P., Makino, Y., Ogawa, H., Rugg-Gunn, A. J., Moynihan, P. J., Petersen, P. E., Evans, R. W., Feldens, C. A., Lo, E. C. M., Khoshnevisan, M. H., et al. (2018) · Community Dentistry And Oral Epidemiology · doi:10.1111/cdoe.12362 · Cited by 318
Research works printed but not linked: 2
- ElevateOralCare. The silver bulletin 1. 2017. Available at: http://www.elevateoralcare.com/Landing-Pages/silverbulletinv1. Accessed September 16, 2018.
- Seberol, 2013, Z. Caries arresting effect of silver diamine fluoride on primary teeth, J Dent Res., Vol. 92
Cited by
Sorted by citations
The Evolving Microbiome of Dental Caries
Spatafora, G. A., Li, Y., He, X., Cowan, A. N., & Tanner, A. C. R. (2024) · Microorganisms · doi:10.3390/microorganisms12010121 · Cited by 341
He, J., Yang, J., Li, M., Li, Y., Pang, Y., Deng, J., Zhang, X., & Liu, W. (2022) · ACS Nano · doi:10.1021/acsnano.1c10812 · Cited by 122
Zhou, J., Zhou, L., Chen, Z.-Y., Sun, J., Guo, X., Wang, H., Zhang, X., Liu, Z., Liu, J., Zhang, K., et al. (2024) · Journal of Dentistry · doi:10.1016/j.jdent.2024.105489 · Cited by 107
Minimally Invasive Therapies for the Management of Dental Caries—A Literature Review
Desai, H., Stewart, C. A., & Finer, Y. (2021) · Dentistry Journal · doi:10.3390/dj9120147 · Cited by 99
Radiation-related caries: current diagnostic, prognostic, and management paradigms
Palmier, N. R., Migliorati, C. A., Ribeiro, A. C. P., de Oliveira, M. C. Q., Filho, A. J. V., de Góes, M. F., Brandão, T. B., Lopes, M. A., & Santos‐Silva, A. R. (2020) · Oral Surgery Oral Medicine Oral Pathology and Oral Radiology · doi:10.1016/j.oooo.2020.04.003 · Cited by 93
Metadata
- Authors
- Crystal, Y. O., & Niederman, R.
- Affiliations
- New York University (US)
- Corresponding author
- Crystal, Yasmi O.
- Venue
- Dental Clinics of North America
- Publisher
- Elsevier BV
- Published
- 2019-01
- Volume
- 63
- Issue
- 1
- Pages
- 45-68
- ISSN
- 0011-8532 (ISSN-L)
- PMC
- PMC6500430
- OpenAlex
- W2901262305
- Cited by
- 253
- References
- 64
- Citations by year
- 2026: 28 · 2025: 38 · 2024: 38 · 2023: 47 · 2022: 46 · 2021: 35 · 2020: 17 · 2019: 4
- FWCI
- 2.04
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Dental Clinics of North America (publishedVersion)
- PubMed (publishedVersion)
- Europe PMC (PubMed Central) (acceptedVersion)
- PubMed Central (acceptedVersion)
- Funders
- National Institutes of Health (R01MD011526)
- Patient-Centered Outcomes Research Institute (PCS-1609-36824)
- Topics
- Health Sciences › Dentistry › General Dentistry › Dental Health and Care Utilization
- Health Sciences › Dentistry › General Dentistry › Dental materials and restorations
- Health Sciences › Dentistry › Oral Surgery › Endodontics and Root Canal Treatments
- Keywords
- silver diamine fluoride, caries arrest, dental caries prevention, primary teeth, root caries, cavitated lesions, caries management, dental caries
- MeSH terms
- Aged, Quaternary Ammonium Compounds, Anti-Bacterial Agents, Cariostatic Agents, Child, Dental Caries, Fluorides, Topical, Humans, Pediatric Dentistry, Tooth Remineralization, Tooth, Deciduous, Patient Satisfaction, Root Caries, Silver Compounds, Evidence-Based Dentistry
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