The DOI matches its Crossref record; 43 of the 43 references it cites were found in a registry or an index.
Ezrin, Radixin and Moesin: key regulators of membrane–cortex interactions and signaling
Open accessAbstract
Summary The cell cortex serves as a critical nexus between the extracellular environment/cell membrane and the underlying cytoskeleton and cytoplasm. In many cells, the cell cortex is organized and maintained by the Ezrin, Radixin and Moesin (ERM) proteins, which have the ability to interact with both the plasma membrane and filamentous actin. Although this membrane-cytoskeletal linkage function is critical to stability of the cell cortex, recent studies indicate that this is only a part of what ERMs do in many cells. In addition to their role in binding filamentous actin, ERMs regulate signaling pathways through their ability to bind transmembrane receptors and link them to downstream signaling components. In this review we discuss recent evidence in a variety of cells indicating that ERMs serve as scaffolds to facilitate efficient signal transduction on the cytoplasmic face of the plasma membrane.
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Cites
ERM proteins and merlin: integrators at the cell cortex
Bretscher, A., Edwards, K., & Fehon, R. G. (2002) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm882 · Cited by 1,306
Self-citationOrganizing the cell cortex: the role of ERM proteins
Fehon, R. G., McClatchey, A. I., & Bretscher, A. (2010) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2866 · Cited by 1,044
Self-citationThe many roles of FAS receptor signaling in the immune system
Strasser, A., Jost, P. J., & Nagata, S. (2009) · Immunity · doi:10.1016/j.immuni.2009.01.001 · Cited by 968
Hall, R. A., Premont, R. T., Chow, C.-W., Blitzer, J. T., Pitcher, J. A., Claing, A., Stoffel, R. H., Barak, L. S., Shenolikar, S., Weinman, E. J., et al. (1998) · Nature · doi:10.1038/33458 · Cited by 585
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Phosphoinositide binding and phosphorylation act sequentially in the activation mechanism of ezrin
Fievet, B. T., Gautreau, A., Roy, C., Del Maestro, L., Mangeat, P., Louvard, D., & Arpin, M. (2004) · The Journal of Cell Biology · doi:10.1083/jcb.200307032 · Cited by 382
The Actin Cytoskeleton in T Cell Activation
Burkhardt, J. K., Carrizosa, E., & Shaffer, M. H. (2008) · Annual Review of Immunology · doi:10.1146/annurev.immunol.26.021607.090347 · Cited by 313
Ezrin is a cyclic AMP-dependent protein kinase anchoring protein
Dransfield, D. T. (1997) · The EMBO Journal · doi:10.1093/emboj/16.1.35 · Cited by 308
ERM-Dependent Movement of CD43 Defines a Novel Protein Complex Distal to the Immunological Synapse
Allenspach, E. J., Cullinan, P., Tong, J., Tang, Q., Tesciuba, A. G., Cannon, J. L., Takahashi, S. M., Morgan, R., Burkhardt, J. K., & Sperling, A. I. (2001) · Immunity · doi:10.1016/s1074-7613(01)00224-2 · Cited by 264
Moesin functions antagonistically to the Rho pathway to maintain epithelial integrity
Speck, O., Hughes, S. C., Noren, N. K., Kulikauskas, R. M., & Fehon, R. G. (2003) · Nature · doi:10.1038/nature01295 · Cited by 248
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Metadata
- Authors
- Neisch, A. L., & Fehon, R. G.
- Venue
- Current Opinion in Cell Biology
- Publisher
- Elsevier BV
- Published
- 2011-08
- Volume
- 23
- Issue
- 4
- Pages
- 377-382
- ISSN
- 0955-0674 (ISSN-L)
- OpenAlex
- W1965831400
- Cited by
- 271
- References
- 43
- FWCI
- 1.46
- Type
- journal article
- Language
- en
- Open access
- green
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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