Iron-Sulfur Protein Biogenesis in Eukaryotes: Components and Mechanisms

Global analysis of protein expression in yeast

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Friedreich's Ataxia: Autosomal Recessive Disease Caused by an Intronic GAA Triplet Repeat Expansion

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Balancing Acts

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Structure, function, and formation of biological iron-sulfur clusters

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The WD repeat: a common architecture for diverse functions

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Regulation of Mitochondrial Iron Accumulation by Yfh1p, a Putative Homolog of Frataxin

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Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits

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The mitochondrial proteins Atm1p and Nfs1p are essential for biogenesis of cytosolic Fe/S proteins

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Assembly of Iron-Sulfur Clusters

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Cysteine desulfurase activity indicates a role for NIFS in metallocluster biosynthesis.

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A Disulfide Relay System in the Intermembrane Space of Mitochondria that Mediates Protein Import

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A Third Bacterial System for the Assembly of Iron-Sulfur Clusters with Homologs in Archaea and Plastids

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Iron–sulphur cluster biogenesis and mitochondrial iron homeostasis

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IscU as a Scaffold for Iron−Sulfur Cluster Biosynthesis: Sequential Assembly of [2Fe-2S] and [4Fe-4S] Clusters in IscU

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Discovery of Two Novel Radical S-Adenosylmethionine Proteins Required for the Assembly of an Active [Fe] Hydrogenase

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Mutation of a Putative Mitochondrial Iron Transporter Gene (ABC7) in X-Linked Sideroblastic Anemia and Ataxia (XLSA/A)

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Mechanism for the Desulfurization of L-Cysteine Catalyzed by the nifS Gene Product

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Components involved in assembly and dislocation of iron–sulfur clusters on the scaffold protein Isu1p

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Coordinated Remodeling of Cellular Metabolism during Iron Deficiency through Targeted mRNA Degradation

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Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria

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Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation

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Deficiency of glutaredoxin 5 reveals Fe-S clusters are required for vertebrate haem synthesis.

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Maturation of cellular Fe–S proteins: an essential function of mitochondria

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Iron−Sulfur Cluster Biosynthesis. Characterization of Frataxin as an Iron Donor for Assembly of [2Fe-2S] Clusters in ISU-Type Proteins

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Respiratory deficiency due to loss of mitochondrial DNA in yeast lacking the frataxin homologue

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Iron‐regulated DNA binding by the AFT1 protein controls the iron regulon in yeast.

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An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1

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Iron–sulfur-protein biogenesis in eukaryotes

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NifS-directed assembly of a transient [2Fe-2S] cluster within the NifU protein

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The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins

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Maturation of cellular Fe-S proteins: an essential function of mitochondria

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The SufE Protein and the SufBCD Complex Enhance SufS Cysteine Desulfurase Activity as Part of a Sulfur Transfer Pathway for Fe-S Cluster Assembly in Escherichia coli

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The cysteine desulfurase, IscS, has a major role in in vivo Fe-S cluster formation in Escherichia coli

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Nitrogenase: standing at the crossroads

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Functions of mitochondrial ISCU and cytosolic ISCU in mammalian iron-sulfur cluster biogenesis and iron homeostasis

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Metal-Responsive Transcription Factors That Regulate Iron, Zinc, and Copper Homeostasis in Eukaryotic Cells

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Complete Characterization of the Human ABC Gene Family

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Evidence for a conserved system for iron metabolism in the mitochondria of Saccharomyces cerevisiae

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Human ABC7 transporter: gene structure and mutation causing X-linked sideroblastic anemia with ataxia with disruption of cytosolic iron-sulfur protein maturation

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Frataxin-mediated Iron Delivery to Ferrochelatase in the Final Step of Heme Biosynthesis

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Transfer of Sulfur from IscS to IscU during Fe/S Cluster Assembly

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The ABC transporter Atm1p is required for mitochondrial iron homeostasis

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A mitochondrial ferredoxin is essential for biogenesis of cellular iron-sulfur proteins

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An essential function of the mitochondrial sulfhydryl oxidase Erv1p/ALR in the maturation of cytosolic Fe/S proteins

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Iron-Sulfur Cluster Biosynthesis

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IscA, an Alternate Scaffold for Fe−S Cluster Biosynthesis

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Functional Assignment of the ORF2-iscS-iscU-iscA-hscB-hscA-fdx-0RF3 Gene Cluster Involved in the Assembly of Fe-S Clusters in Escherichia coli

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Biogenesis of iron–sulfur proteins in plants

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Mitochondrial changes associated with glutathione deficiency

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Activation of the Iron Regulon by the Yeast Aft1/Aft2 Transcription Factors Depends on Mitochondrial but Not Cytosolic Iron-Sulfur Protein Biogenesis

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The Nfs1 interacting protein Isd11 has an essential role in Fe/S cluster biogenesis in mitochondria

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A Mutation of the Mitochondrial ABC Transporter Sta1 Leads to Dwarfism and Chlorosis in the Arabidopsis Mutant starik

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Fe-only hydrogenases: structure, function and evolution

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Maturation of Cytosolic Iron-Sulfur Proteins Requires Glutathione

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Biogenesis of Fe-S Cluster by the Bacterial Suf System

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Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1)

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The Interface Between the Biological and Inorganic Worlds: Iron-Sulfur Metalloclusters

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Essential role of Isd11 in mitochondrial iron–sulfur cluster synthesis on Isu scaffold proteins

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Interaction of the iron–sulfur cluster assembly protein IscU with the Hsc66/Hsc20 molecular chaperone system of Escherichia coli

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Great Metalloclusters in Enzymology

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Role of the ABC Transporter Mdl1 in Peptide Export from Mitochondria

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Iron-Sulfur Cluster Assembly

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The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron–sulfur cluster biogenesis

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Catalytic formation of a nitrogenase iron-sulfur cluster.

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The hydrogenase‐like Nar1p is essential for maturation of cytosolic and nuclear iron–sulphur proteins

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Formation and Insertion of the Nitrogenase Iron−Molybdenum Cofactor

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Transcriptional Remodeling in Response to Iron Deprivation in<i>Saccharomyces cerevisiae</i>

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Transcription of the Yeast Iron Regulon Does Not Respond Directly to Iron but Rather to Iron-Sulfur Cluster Biosynthesis

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Yeast Mitochondrial Protein, Nfs1p, Coordinately Regulates Iron-Sulfur Cluster Proteins, Cellular Iron Uptake, and Iron Distribution

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The iscS Gene in Escherichia coli Is Required for the Biosynthesis of 4-Thiouridine, Thiamin, and NAD

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Hydrogenases: active site puzzles and progress

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Distinct iron-sulfur cluster assembly complexes exist in the cytosol and mitochondria of human cells

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Sulfur Transfer from IscS to IscU: The First Step in Iron−Sulfur Cluster Biosynthesis

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Subcellular compartmentalization of human Nfu, an iron-sulfur cluster scaffold protein, and its ability to assemble a [4Fe-4S] cluster

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Aft2p, a Novel Iron-regulated Transcription Activator That Modulates, with Aft1p, Intracellular Iron Use and Resistance to Oxidative Stress in Yeast

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A Specific Role of the Yeast Mitochondrial Carriers Mrs3/4p in Mitochondrial Iron Acquisition under Iron-limiting Conditions

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Saccharomyces cerevisiae ISU1 and ISU2: members of a well-conserved gene family for iron-sulfur cluster assembly

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Crystal Structure of IscS, a Cysteine Desulfurase from Escherichia coli

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Suppressors of Superoxide Dismutase (SOD1) Deficiency in Saccharomyces cerevisiae

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A flavoprotein oxidase defines a new endoplasmic reticulum pathway for biosynthetic disulphide bond formation

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Mitochondrial Control of Iron Homeostasis

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Iron–sulfur protein maturation in human cells: evidence for a function of frataxin

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Subcellular Localization of Aft1 Transcription Factor Responds to Iron Status in Saccharomyces cerevisiae

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Role of Saccharomyces cerevisiae ISA1 and ISA2 in Iron Homeostasis

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Deletion of the Mitochondrial Carrier Genes MRS3 andMRS4 Suppresses Mitochondrial Iron Accumulation in a Yeast Frataxin-deficient Strain

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Mechanism of Iron Transport to the Site of Heme Synthesis inside Yeast Mitochondria

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Mechanisms of iron–sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes

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MnmA and IscS Are Required for in Vitro 2-Thiouridine Biosynthesis in Escherichia coli

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Molecular aspects of iron-sulfur protein maturation

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