A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

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Capturing Chromosome Conformation

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A model for p53-induced apoptosis

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The ENCODE (ENCyclopedia Of DNA Elements) Project

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Genome-Wide Location and Function of DNA Binding Proteins

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Thirty biologically interpretable clusters of transcription factors distinguish cancer type

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Rely on Each Other: DNA Binding Cooperativity Shapes p53 Functions in Tumor Suppression and Cancer Therapy

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Arsenic-induced S phase cell cycle lengthening is associated with ROS generation, p53 signaling and CDC25A expression

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Medicina de sistemas: una nueva visión de la práctica clínica

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Induction of TRIM22 by IFN-γ Involves JAK and PC-PLC/PKC, but Not MAPKs and pI3K/Akt/mTOR Pathways

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Checkpoint protein Rad9 plays an important role in nucleotide excision repair

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Carbazole–pyrrolo[2,1-c][1,4]benzodiazepine conjugates: design, synthesis, and biological evaluation

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PARK7 Diminishes Oxidative Stress-Induced Mucosal Damage in Celiac Disease

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Transcription activity is required for p53-dependent tumor suppression

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p53 regulation of podosome formation and cellular invasion in vascular smooth muscle cells

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Circadian transcription in liver

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Systems medicine: A new approach to clinical practice

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Chapter 17 Dissection of Chick Genomic Regulatory Regions

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DNA Sequence Motif

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Inferring functional transcription factor-gene binding pairs by integrating transcription factor binding data with transcription factor knockout data

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p53 as the main traffic controller of the cell signaling network

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Acquisition of taxane resistance by p53 inactivation in ovarian cancer cells

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The E3 Ligases in Cervical Cancer and Endometrial Cancer

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SOMAscan Proteomics Identifies Novel Plasma Proteins in Amyotrophic Lateral Sclerosis Patients

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Global analysis of in vivo EGR1‐binding sites in erythroleukemia cell using chromatin immunoprecipitation and massively parallel sequencing

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p53 functions and cell lines: Have we learned the lessons from the past?

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ChIP'ing the mammalian genome: technical advances and insights into functional elements

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SKA3 Serves as a Biomarker for Poor Prognosis in Kidney Renal Papillary Cell Carcinoma

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A Regulatory Loop Composed of RAP80-HDM2-p53 Provides RAP80-enhanced p53 Degradation by HDM2 in Response to DNA Damage

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MAMOT: hidden Markov modeling tool

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Restriction of human herpesvirus 6B replication by p53

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Mdm2 mediates FMRP- and Gp1 mGluR-dependent protein translation and neural network activity

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Tackling the epigenome in the pluripotent stem cells

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p53 Pre- and Post-Binding Event Theories Revisited: Stresses Reveal Specific and Dynamic p53-Binding Patterns on the p21 Gene Promoter

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Doxorubicin and 5-fluorouracil induced accumulation and transcriptional activity of p53 are independent of the phosphorylation at serine 15 in MCF-7 breast cancer cells

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LncRNA LENGA acts as a tumor suppressor in gastric cancer through BRD7/TP53 signaling

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Cестрины – шлагбаумы на путях от стресса к старению и болезням

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Advances in drug development for targeted therapies for glioblastoma

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P53 long noncoding RNA regulatory network in cancer development

Surendar, A., Younus, L. A., Lafta, M. H., Markov, A. A., Enina, Y. I., Yushchenko, N., Thangavelu, L. P., Mostafavi, S. M., Pokrovskii, M. V., & Ahmadi, M. (2021) · Cell Biology International · doi:10.1002/cbin.11600 · Cited by 15

Role of Cell Division Autoantigen 1 (CDA1) in Cell Proliferation and Fibrosis

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Induced pluripotent stem cells of patients with Tetralogy of Fallot reveal transcriptional alterations in cardiomyocyte differentiation

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The Effect of Neddylation Blockade on Slug-Dependent Cancer Cell Migration Is Regulated by p53 Mutation Status

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Identification of NEEP21, encoding neuron-enriched endosomal protein of 21 kDa, as a transcriptional target of tumor suppressor p53

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The antagonism between MCT-1 and p53 affects the tumorigenic outcomes

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A New Isoquinolinium Derivative, Cadein1, Preferentially Induces Apoptosis in p53-defective Cancer Cells with Functional Mismatch Repair via a p38-dependent Pathway

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Transcriptional induction of protein kinase C delta by p53 tumor suppressor in the apoptotic response to DNA damage

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Cisatracurium Retards Cell Migration and Invasion Upon Upregulation of p53 and Inhibits the Aggressiveness of Colorectal Cancer

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Whole Genome Expression Profiling Shows that BRG1 Transcriptionally Regulates UV Inducible Genes and Other Novel Targets in Human Cells

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The 3′ flanking region of the human ABO histo-blood group gene is involved in negative regulation of gene expression

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Formation of stress-specific p53 binding patterns is influenced by chromatin but not by modulation of p53 binding affinity to response elements †

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Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice

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Identification of a functional p53 responsive element within the promoter of XAF1 gene in gastrointestinal cancer cells

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DNA Damage Response Pathways and Cancer

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RNA−p53 Interactions in Vitro

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Susceptibility to metanephric apoptosis in bradykinin B2 receptor null mice via the p53-Bax pathway

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ER stress-induced modulation of neural activity and seizure susceptibility is impaired in a fragile X syndrome mouse model

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The ASPP proteins complex and cooperate with p300 to modulate the transcriptional activity of p53

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Adenovirus-mediated p53 and ING4 gene co-transfer elicits synergistic antitumor effects through enhancement of p53 acetylation in breast cancer

Wu, J., Zhu, Y., XU, C., Xu, H., Zhou, X., Yang, J., Xie, Y., & Tao, M. (2015) · Oncology Reports · doi:10.3892/or.2015.4385 · Cited by 13

ChIP for Identification of p53 Responsive DNA Promoters

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INKA2, a novel p53 target that interacts with the serine/threonine kinase PAK4

Liu, Y., Tanikawa, C., Ueda, K., & Matsuda, K. (2019) · International Journal of Oncology · doi:10.3892/ijo.2019.4786 · Cited by 13

Encoding and Decoding of p53 Dynamics in Cellular Response to Stresses

Wang, P., Wang, H., Gao, X., Zhu, H.-X., Zhang, X., Liu, F., & Wang, W. (2023) · Cells · doi:10.3390/cells12030490 · Cited by 13

Hypermethylation of potential tumor suppressor miR-34b/c is correlated with late clinical stage in patients with soft tissue sarcomas

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Regulation of collagen-derived antiangiogenic factors by p53

Assadian, S., & Teodoro, J. G. (2008) · Expert Opinion on Biological Therapy · doi:10.1517/14712598.8.7.941 · Cited by 13

Molecular Basis for Modulation of the p53 Target Selectivity by KLF4

Brandt, T., Townsley, F. M., Teufel, D. P., Freund, S. M. V., & Veprintsev, D. B. (2012) · PLoS ONE · doi:10.1371/journal.pone.0048252 · Cited by 14

Genome-wide analysis of p53-regulated transcription in Myc-driven lymphomas

Tonelli, C., Morelli, M. J., Sabò, A., Verrecchia, A., Rotta, L., Capra, T., Bianchi, S., Campaner, S., & Amati, B. B. (2017) · Oncogene · doi:10.1038/onc.2016.443 · Cited by 13

TBP-like Protein (TLP) Disrupts the p53-MDM2 Interaction and Induces Long-lasting p53 Activation

Maeda, R., Tamashiro, H., Takano, K., Takahashi, H., Suzuki, H., Saito, S., Kojima, W., Adachi, N., Ura, K., Endo, T., et al. (2017) · Journal of Biological Chemistry · doi:10.1074/jbc.m116.763318 · Cited by 13

Identifying Differential Histone Modification Sites from ChIP‐seq Data

Han, X., & Sung, W.-K. K. (2011) · Methods in molecular biology · doi:10.1007/978-1-61779-400-1_19 · Cited by 13

Helpers of the cellular gatekeeper—miRNAs dance in P53 network

Shi, M., Liu, D., Shen, B., & Guo, N. (2009) · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer · doi:10.1016/j.bbcan.2009.12.001 · Cited by 13

Focused PCR Screen Reveals p53 Dependence of Nitric Oxide-Induced Apoptosis and Up-Regulation of Maspin and Plasminogen Activator Inhibitor-1 in Tumor Cells

Lim, S., Hung, A. C., & Porter, A. G. (2009) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-08-0331 · Cited by 13

Genome Sequencing Technology and Algorithms

Kim, S., Tang, H., & Mardis, E. R. (2007) · Cited by 13

Wnt/β‐catenin‐mediated transcriptional regulation

Parker, D. S., Blauwkamp, T. A., & Cadigan, K. M. (2007) · Advances in developmental biology · doi:10.1016/s1574-3349(06)17001-5 · Cited by 14

Novel function of PERP-428 variants impacts lung cancer risk through the differential regulation of PTEN/MDM2/p53-mediated antioxidant activity

Liao, C., Yang, S., Wu, T.-J., Han, C. L., Huang, C. F., Liu, Y.-F., Wang, C.-H., Liou, J.-C., Hsu, S., Lee, H., et al. (2021) · Free Radical Biology and Medicine · doi:10.1016/j.freeradbiomed.2021.02.017 · Cited by 12

Synthesizing genome regulation data with vote-counting

Fischer, M., & Hoffmann, S. (2022) · Trends in Genetics · doi:10.1016/j.tig.2022.06.012 · Cited by 12

Dose-dependent and gender-related radiation-induced transcription alterations of Gadd45a and Ier5 inhuman lymphocytes exposed to gamma ray emitted by 60Co

Tavakoli, H., Manoochehri, M., Mosalla, S. M. M., Ghafori, M., & Karimi, A. A. (2012) · Radiation Protection Dosimetry · doi:10.1093/rpd/ncs164 · Cited by 12

Retrotransposon‐derived p53 binding sites enhance telomere maintenance and genome protection

Lieberman, P. M. (2016) · BioEssays · doi:10.1002/bies.201600078 · Cited by 12

Yeast genome analysis identifies chromosomal translocation, gene conversion events and several sites of Ty element insertion

Shibata, Y., Malhotra, A., Bekiranov, S., & Dutta, A. (2009) · Nucleic Acids Research · doi:10.1093/nar/gkp650 · Cited by 11

The kinetics of p53‐binding and histone acetylation at target promoters do not strictly correlate with gene expression after UV damage

Magrini, R., Russo, D., Fronza, G., Inga, A., & Menichini, P. (2006) · Journal of Cellular Biochemistry · doi:10.1002/jcb.21122 · Cited by 12

Pathway aberrations of murine melanoma cells observed in Paired-End diTag transcriptomes

Chiu, K. P., Ariyaratne, P. N., Han, X., Tan, A. K. S., Ng, P., Liu, E. T., Ruan, Y., Wei, C., & Sung, W.-K. K. (2007) · BMC Cancer · doi:10.1186/1471-2407-7-109 · Cited by 12

DISPARE: DIScriminative PAttern REfinement for Position Weight Matrices

da Piedade, I., Tang, M. E., & Elemento, O. (2009) · BMC Bioinformatics · doi:10.1186/1471-2105-10-388 · Cited by 11

Interrogating the genome to understand oestrogen-receptor-mediated transcription

Dietz, S., & Carroll, J. (2008) · Expert Reviews in Molecular Medicine · doi:10.1017/s1462399408000653 · Cited by 14

Modeling of DNA Damage Repair and Cell Response in Relation to p53 System Exposed to Ionizing Radiation

Hu, A., Zhou, W., Wu, Z., Zhang, H., Li, J., & Qiu, R. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911323 · Cited by 11

Integrative biology — a strategy for systems biomedicine

Liu, E. T. (2008) · Nature Reviews Genetics · doi:10.1038/nrg2488 · Cited by 11

fdrMotif: identifyingcis-elements by an EM algorithm coupled with false discovery rate control

Li, L., Bass, R. L., & Liang, Y. (2008) · Bioinformatics · doi:10.1093/bioinformatics/btn009 · Cited by 11

Targeting cyclooxygenase by indomethacin decelerates progression of acute lymphoblastic leukemia in a xenograft model

Richartz, N., Duthil, E., Ford, A. M., Naderi, E. H., Bhagwat, S., Gilljam, K. M., Burman, M. M., Ruud, E., Blomhoff, H. K., & Skah, S. (2019) · Blood Advances · doi:10.1182/bloodadvances.2019000473 · Cited by 11

Analysis of the p53/microRNA Network in Cancer

Kaller, M., Hünten, S., Siemens, H., & Hermeking, H. (2022) · Advances in experimental medicine and biology · doi:10.1007/978-3-031-08356-3_7 · Cited by 12

Novel delivery system with a dual–trigger release of savory essential oil by mesoporous silica nanospheres and its possible targets in leukemia cancer cells: in vitro study

AbouAitah, K., Hassan, H. A., Ammar, N. M., Baker, D. H. A., Higazy, I. M., Shaker, O. G., El-Sayed, A., & Hassan, A. M. E. (2023) · Cancer Nanotechnology · doi:10.1186/s12645-022-00152-9 · Cited by 12

Towards a genome-wide reconstruction of cis-regulatory networks in the human genome

Cecchini, K. R., Banerjee, A. R., & Kim, T. H. (2009) · Seminars in Cell and Developmental Biology · doi:10.1016/j.semcdb.2009.06.005 · Cited by 11

p53 – ein natürlicher Krebskiller: Einsichten in die Struktur und Therapiekonzepte

Römer, L., Klein, C., Dehner, A., Kessler, H., & Büchner, J. (2006) · Angewandte Chemie · doi:10.1002/ange.200600611 · Cited by 12

In silico regulatory analysis for exploring human disease progression

Holloway, D. T., Kon, M., & DeLisi, C. (2008) · Biology Direct · doi:10.1186/1745-6150-3-24 · Cited by 11

Transcriptional Regulation of the Albumin Gene Depends on the Removal of Histone Methylation Marks by the FAD-Dependent Monoamine Oxidase Lysine-Specific Demethylase 1 in HepG2 Human Hepatocarcinoma Cells

Liu, D., & Zempleni, J. (2014) · Journal of Nutrition · doi:10.3945/jn.114.192187 · Cited by 11

Using the Gibbs Motif Sampler for Phylogenetic Footprinting

Thompson, W. A., Conlan, S., McCue, L. A., & Lawrence, C. E. (2007) · Methods in molecular biology · doi:10.1007/978-1-59745-514-5_25 · Cited by 11

Ubiquitin Ligase TRIM22 Inhibits Ovarian Cancer Malignancy via TCF4 Degradation

Tao, T., Zhang, Y., Guan, C., Wang, S., Liu, X., & Wang, M. (2024) · Molecular Cancer Research · doi:10.1158/1541-7786.mcr-23-0962 · Cited by 10

Deciphering the molecular mechanism underlying morphology transition in two-component DNA-protein cophase separation

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Genome-wide studies of the transcriptional regulation by p53

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