The ENCODE (ENCyclopedia Of DNA Elements) Project
Abstract
The ENCyclopedia Of DNA Elements (ENCODE) Project aims to identify all functional elements in the human genome sequence. The pilot phase of the Project is focused on a specified 30 megabases (approximately 1%) of the human genome sequence and is organized as an international consortium of computational and laboratory-based scientists working to develop and apply high-throughput approaches for detecting all sequence elements that confer biological function. The results of this pilot phase will guide future efforts to analyze the entire human genome.
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ENCODE found that about 80% of the human genome is transcribed, which suggests that it is functional.
“ENCODE found that about 80% of the human genome is transcribed, which suggests that it is functional.”
From Opinion: The Key Steps in the Origin of Life to the Formation of the Eukaryotic Cell (2024) · cites this paper as [149]
ATG9A is among SREBF1 target genes.
“ATG9A was found among the SREBF1 target genes in ChIP-seq experiments [64]”
From miRNA family miR-29 inhibits PINK1-PRKN signaling via ATG9A (2026) · cites this paper as [64]
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miRNA family miR-29 inhibits PINK1-PRKN signaling via ATG9A
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- Venue
- Science
- Published
- 2004-10-22
- Volume
- 306
- Issue
- 5696
- Pages
- 636-640
- ISSN
- 0036-8075 (ISSN-L)
- 1095-9203
- OpenAlex
- W2247766769
- Cited by
- 2,390
- References
- 4
- Citations by year
- 2026: 54 · 2025: 82 · 2024: 108 · 2023: 123 · 2022: 114 · 2021: 169 · 2020: 165 · 2019: 140 · 2018: 118 · 2017: 113 · 2016: 139 · 2015: 147 · 2014: 110 · 2013: 108 · 2012: 80
- FWCI
- 39.87
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Science (publishedVersion)
- PubMed (publishedVersion)
- Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory) (acceptedVersion)
- ENLIGHTEN (Jurnal Bimbingan dan Konseling Islam) (acceptedVersion)
- CaltechAUTHORS (California Institute of Technology) (submittedVersion)
- IRIS (submittedVersion)
- Research Portal (King's College London) (submittedVersion)
- SERVAL (Université de Lausanne) (submittedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Chromatin Dynamics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Genomics and Phylogenetic Studies
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioinformatics and Genomic Networks
- Keywords
- ENCODE, human genome, functional elements, non-coding DNA, high-throughput genomics, genome annotation, pilot phase, international research consortium
- MeSH terms
- Animals, Humans, National Institutes of Health (U.S.), Pilot Projects, Proteins, Publishing, Regulatory Sequences, Nucleic Acid, United States, Genome, Human, Conserved Sequence, Sequence Analysis, DNA, Evolution, Molecular, Computational Biology, Internet, Access to Information, Genomics, Databases, Nucleic Acid, Information Dissemination
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