Diverse Cellular Functions of the Hsp90 Molecular Chaperone Uncovered Using Systems Approaches

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Items 101–200 of 476

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2. Structural characterization of the Get4/Get5 complex and its interaction with Get3
   Justin William Chartron, Christian J. M. Suloway, Ma’ayan Zaslaver, William Clemons · 2010 · Proceedings of the National Academy of Sciences
3. Functional principles and regulation of molecular chaperones
   Vinay Dahiya, Johannes Büchner · 2018 · Advances in protein chemistry and structural biology
4. Heat shock proteins and exosomes in cancer theranostics
   Mathilde Regimbeau, Jimena Abrey, Valentin Vautrot, Sébastien Causse, Jessica Gobbo, Carmen Garrido · 2021 · Seminars in Cancer Biology
5. Protective Role of Heat Shock Proteins in Parkinson’s Disease
   Paolo Aridon, Fabiana Geraci, Giuseppina Turturici, Marco D’Amelio, Giovanni Savettieri, Gabriella Sconzo · 2011 · Neurodegenerative Diseases
6. Regulatory role of the 90-kDa-heat-shock protein (Hsp90) and associated factors on gene expression
   Alejandra G. Erlejman, Mariana Lagadari, Judith Toneatto, Graciela Piwien‐Pilipuk, Mario D. Galigniana · 2014 · Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms
7. Soluble guanylyl cyclase requires heat shock protein 90 for heme insertion during maturation of the NO-active enzyme
   Arnab Ghosh, Dennis J. Stuehr · 2012 · Proceedings of the National Academy of Sciences
8. Allosteric Modulation of Human Hsp90α Conformational Dynamics
   David L. Penkler, Canan Atılgan, Özlem Taştan Bishop · 2018 · Journal of Chemical Information and Modeling
9. Sti1 Regulation of Hsp70 and Hsp90 Is Critical for Curing of Saccharomyces cerevisiae [ PSI + ] Prions by Hsp104
   Michael J. Reidy, Daniel C. Masison · 2010 · Molecular and Cellular Biology
10. Involvement of molecular chaperone in protein-misfolding brain diseases.
    N. Wankhede, Mayur B. Kale, A. Upaganlawar, B. Taksande, M. Umekar, T. Behl, A. Abdellatif, Prasanna Mohana Bhaskaran, Sudarshan Reddy Dachani, Aayush Sehgal et al. · 2022 · Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie
11. Chaperoning stem cells: a role for heat shock proteins in the modulation of stem cell self‐renewal and differentiation?
    Earl Prinsloo, Mokgadi M. Setati, Victoria M. Longshaw, Gregory L. Blatch · 2009 · BioEssays
12. HSP 90 and co‐chaperones: a multitaskers’ view on plant hormone biology
    Martin Di Donato, Markus M. Geisler · 2019 · FEBS Letters
13. Cdc28 provides a molecular link between Hsp90, morphogenesis, and cell cycle progression in<i>Candida albicans</i>
    Senn, Heather, Shapiro, Rebecca S., Cowen, Leah E. · 2012 · Molecular Biology of the Cell
14. Hsp90 Inhibitors Are Efficacious against Kaposi Sarcoma by Enhancing the Degradation of the Essential Viral Gene LANA, of the Viral Co-Receptor EphA2 as well as Other Client Proteins
    Wuguo Chen, Sang‐Hoon Sin, Kwun Wah Wen, Blossom Damania, Dirk P. Dittmer · 2012 · PLoS Pathogens
15. HSP90/70 chaperones are required for rapid nucleosome removal upon induction of the GAL genes of yeast
    Monique Floer, Gene O. Bryant, Mark Ptashne · 2008 · Proceedings of the National Academy of Sciences
16. The conserved arginine 380 of Hsp90 is not a catalytic residue, but stabilizes the closed conformation required for ATP hydrolysis
    Christian N. Cunningham, Daniel R. Southworth, Kristin A. Krukenberg, David A. Agard · 2012 · Protein Science
17. A relationship between mRNA expression levels and protein solubility in E. coli
    Tartaglia, Gian Gaetano, Pechmann, Sebastian, Dobson, Christopher M., Vendruscolo, Michele · 2009 · Journal of Molecular Biology
18. Downregulation of the Hsp90 System Causes Defects in Muscle Cells of Caenorhabditis Elegans
    Andreas M. Gaiser, Christoph J. O. Kaiser, Veronika Haslbeck, Klaus Richter · 2011 · PLoS ONE
19. The crossroads between cancer stem cells and aging
    Sara Santos Franco, Hadas Raveh-Amit, Julianna Kobolák, Mohammed H Al-Qahtani, Ali Mobasheri, András Dinnyés · 2015 · BMC Cancer
20. The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range
    Hannah Girstmair, Franziska Tippel, Abraham López, Katarzyna M. Tych, Frank Stein, Per Haberkant, Philipp W. N. Schmid, Dominic Helm, Matthias Rief, Michael Sattler et al. · 2019 · Nature Communications
21. The burden of trisomy 21 disrupts the proteostasis network in Down syndrome
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22. Client binding shifts the populations of dynamic Hsp90 conformations through an allosteric network
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23. Cascade-responsive nano-assembly for efficient photothermal-chemo synergistic inhibition of tumor metastasis by targeting cancer stem cells
    Xianqi Zhu, Lin Li, Jin Tang, Chunyu Yang, Hao Yu, Kunpeng Liu, Ziyan Zheng, Xinggui Gu, Qingsong Yu, Fu‐Jian Xu et al. · 2021 · Biomaterials
24. HSP90 Supports Tumor Growth and Angiogenesis through PRKD2 Protein Stabilization
    Ninel Azoitei, Kristina Diepold, Cornelia Brunner, A. MAUREEN ROUHI, Felicitas Genze, Alexander Becher, Hans Armin Kestler, Johan Van Lint, Gabriela Chiosis, John Koren et al. · 2014 · Cancer Research
25. Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones
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26. Stress response in tardigrades: differential gene expression of molecular chaperones
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27. Heat Shock Proteins In Cancer: Targeting the ‘Chaperones’
    Zeina A. Nahleh, Arafat Tfayli, Ali Abd Ali Mohammed Najm, A El Sayed, Zaher A. Nahle · 2012 · Future Medicinal Chemistry
28. Hsp90@chromatin.nucleus: an emerging hub of a networker
    Ritwick Sawarkar, Renato Paro · 2013 · Trends in Cell Biology
29. Rewiring of Signaling Networks Modulating Thermotolerance in the Human Pathogen Cryptococcus neoformans
    Dong‐Hoon Yang, Kwang‐Woo Jung, Soohyun Bang, Jang-Won Lee, Min-Hee Song, Anna Floyd Averette, Richard A. Festa, Giuseppe Ianiri, Alexander Idnurm, Dennis J. Thiele et al. · 2016 · Genetics
30. The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions
    Janhavi A. Kolhe, Neethu L. Babu, Brian Freeman · 2023 · Molecular Cell
31. Canonical and Kinase Activity-Independent Mechanisms for Extracellular Signal-Regulated Kinase 5 (ERK5) Nuclear Translocation Require Dissociation of Hsp90 from the ERK5-Cdc37 Complex
    Tatiana Erazo, Ana Moreno, Gerard Ruiz‐Babot, Arantza Rodríguez-Asiain, Nicholas A. Morrice, Josep Espadamala, José Ramón Bayascas, Néstor Gómez, José Miguel Lizcano · 2013 · Molecular and Cellular Biology
32. Control of Hsp90 chaperone and its clients by N-terminal acetylation and the N-end rule pathway
    Jang‐Hyun Oh, Ju-Yeon Hyun, Alexander J. Varshavsky · 2017 · Proceedings of the National Academy of Sciences
33. Ciliary dynein motor preassembly is regulated by Wdr92 in association with HSP90 co-chaperone, R2TP
    Petra zur Lage, Panagiota Stefanopoulou, Katarzyna Styczynska‐Soczka, Niall Quinn, Girish R. Mali, Alex von Kriegsheim, Pleasantine Mill, Andrew P. Jarman · 2018 · The Journal of Cell Biology
34. Approaches for defining the Hsp90-dependent proteome
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35. HSP90 manages the ends
    Diane C. DeZwaan, Brian Freeman · 2010 · Trends in Biochemical Sciences
36. Extracellular vesicle mediated molecular signaling in ovarian follicle: Implication for oocyte developmental competence
    Dawit Tesfaye, Tsige Hailay, Dessie Salilew‐Wondim, Michael Hoelker, Simret Bitseha, Samuel Gebremedhn · 2020 · Theriogenology
37. Probing Molecular Mechanisms of the Hsp90 Chaperone: Biophysical Modeling Identifies Key Regulators of Functional Dynamics
    Anshuman Dixit, Gennady M. Verkhivker · 2012 · PLoS ONE
38. Mechanisms of protein homeostasis (proteostasis) maintain stem cell identity in mammalian pluripotent stem cells
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39. The Non-canonical Hop Protein from Caenorhabditis elegans Exerts Essential Functions and Forms Binary Complexes with Either Hsc70 or Hsp90
    Andreas M. Gaiser, Florian Brandt, Klaus Richter · 2009 · Journal of Molecular Biology
40. Understanding the mechanism of β‐sheet folding from a chemical and biological perspective
    Markus Jäger, Songpon Deechongkit, Edward K. Koepf, Houbi Nguyen, Jianmin Gao, Evan T. Powers, Martin Gruebele, Jeffery W. Kelly · 2008 · Biopolymers
41. Hsp90: From Cellular to Organismal Proteostasis
    Milán Somogyvári, Saba Khatatneh, Csaba Sőti · 2022 · Cells
42. Proteomic analysis of protein homeostasis and aggregation
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43. Squaring the EMC – how promoting membrane protein biogenesis impacts cellular functions and organismal homeostasis
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44. Global proteomic analyses define an environmentally contingent Hsp90 interactome and reveal chaperone-dependent regulation of stress granule proteins and the R2TP complex in a fungal pathogen
    O’Meara, Teresa R., O’Meara, Matthew J., Polvi, Elizabeth J., Pourhaghighi, M. Reza, Liston, Sean D., Lin, Zhen-Yuan, Veri, Amanda O., Emili, Andrew, Gingras, Anne-Claude, Cowen, Leah E. · 2019 · PLoS Biology
45. Molecular response of Saccharomyces cerevisiae wine and laboratory strains to high sugar stress conditions
    Elena Jiménez-Martí, Aurora Zuzuarregui, Mercè Gomar‐Alba, Dolores Gutiérrez, Concha Gil, Marcel·lí del Olmo · 2011 · International Journal of Food Microbiology
46. The Hsp90 mosaic: a picture emerges
    Matthias P. Mayer, Chrisostomos Prodromou, Judith Frydman · 2009 · Nature Structural & Molecular Biology
47. Tumor-Intrinsic and Tumor-Extrinsic Factors Impacting Hsp90-Targeted Therapy
    S. Alarcon, M. Mollapour, Min-Jung Lee, Shinji Tsutsumi, Sunmin Lee, Y. Kim, T. Prince, A. Apolo, G. Giaccone, Wan-Ping Xu et al. · 2012 · Current molecular medicine
48. Hsp70s and J proteins of Plasmodium parasites infecting rodents and primates: structure, function, clinical relevance, and drug targets.
    J. Njunge, M. Ludewig, A. Boshoff, E. Pesce, G. Blatch · 2012 · Current pharmaceutical design
49. Ydj1 governs fungal morphogenesis and stress response, and facilitates mitochondrial protein import via Mas1 and Mas2
    Jinglin Lucy Xie, Iryna Bohovych, Erin O. Y. Wong, Jean‐Philippe Lambert, Anne‐Claude Gingras, Oleh Khalimonchuk, Leah E. Cowen, Michelle D. Leach · 2017 · Microbial Cell
50. Roles of Hsp90 in Candida albicans morphogenesis and virulence
    Nicole Robbins, Leah E. Cowen · 2023 · Current Opinion in Microbiology
51. Applying chaperones to protein-misfolding disorders: Molecular chaperones against α-synuclein in Parkinson's disease
    Ali Châari, Jessica Hoarau-Véchot, Moncef M. Ladjimi · 2013 · International Journal of Biological Macromolecules
52. Protective effect of gedunin on TLR-mediated inflammation by modulation of inflammasome activation and cytokine production: Evidence of a multitarget compound
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53. Physical plasma-triggered ROS induces tumor cell death upon cleavage of HSP90 chaperone
    Sander Bekeschus, Maxi Lippert, Kristina Diepold, Gabriela Chiosis, Thomas Theodor Werner Seufferlein, Ninel Azoitei · 2019 · Scientific Reports
54. Probing Allosteric Inhibition Mechanisms of the Hsp70 Chaperone Proteins Using Molecular Dynamics Simulations and Analysis of the Residue Interaction Networks
    Gabrielle Stetz, Gennady M. Verkhivker · 2016 · Journal of Chemical Information and Modeling
55. Hsp90 and p23 Molecular Chaperones Control Chromatin Architecture by Maintaining the Functional Pool of the RSC Chromatin Remodeler
    Frank Echtenkamp, Zlata Gvozdenov, Nicholas L. Adkins, Yang Zhang, Melinda A. Lynch-Day, Shinya Watanabe, Craig L. Peterson, Brian Freeman · 2016 · Molecular Cell
56. The Co-chaperone Cns1 and the Recruiter Protein Hgh1 Link Hsp90 to Translation Elongation via Chaperoning Elongation Factor 2
    Florian H. Schopf, Eva Maria Huber, Christopher Dodt, Abraham López, Maximilian M. Biebl, Daniel Andreas Rutz, Moritz Mühlhofer, Gesa Richter, Tobias Madl, Michael Sattler et al. · 2019 · Molecular Cell
57. Hsp90 S-nitrosylation at Cys521, as a conformational switch, modulates cycling of Hsp90-AHA1-CDC37 chaperone machine to aggravate atherosclerosis
    Shuang Zhao, Xin Tang, Zian Miao, Yurong Chen, Jiawei Cao, Tianyu Song, Daiting You, Yanqing Zhong, Zhe Lin, Dan Wang et al. · 2022 · Redox Biology
58. Novel Hsp90 partners discovered using complementary proteomic approaches
    Tsaytler, Pavel A., Krijgsveld, Jeroen, Goerdayal, Soenita S., Rüdiger, Stefan, Egmond, Maarten R. · 2009 · Cell Stress and Chaperones
59. Heat shock protein 90 regulates phosphatidylinositol 3‐kinase‐related protein kinase family proteins together with the RUVBL1/2 and Tel2‐containing co‐factor complex
    Natsuko Izumi, Akio Yamashita, Hisashi Hirano, Shigeo Ohno · 2011 · Cancer Science
60. The complementation of yeast with human or Plasmodium falciparum Hsp90 confers differential inhibitor sensitivities
    Diana Wider, Marie‐Pierre Gulli, Pierre-André Briand, Utpal Shashikant Tatu, Didier Picard · 2009 · Molecular and Biochemical Parasitology
61. Hsp90 inhibition differentially destabilises MAP kinase and TGF-beta signalling components in cancer cells revealed by kinase-targeted chemoproteomics
    Armin Haupt, Gérard Joberty, Marcus Bantscheff, Holger Fröhlich, Henning Stehr, Michal R. Schweiger, Axel Fischer, Martin Kerick, Stefan T. Boerno, Andreas Dahl et al. · 2012 · BMC Cancer
62. Progress and prospects for targeting Hsp90 to treat fungal infections
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63. Nprl3 is required for normal development of the cardiovascular system
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64. Chaperones and chaperone–substrate complexes: Dynamic playgrounds for NMR spectroscopists
    Björn M. Burmann, Sebastian Hiller · 2015 · Progress in Nuclear Magnetic Resonance Spectroscopy
65. Quantitative proteomics of the yeast Hsp70/Hsp90 interactomes during DNA damage reveal chaperone-dependent regulation of ribonucleotide reductase
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66. Hsp90
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67. Mapping the Hsp90 Genetic Network Reveals Ergosterol Biosynthesis and Phosphatidylinositol-4-Kinase Signaling as Core Circuitry Governing Cellular Stress
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68. Discovery and Optimization of Small Molecules Targeting the Protein–Protein Interaction of Heat Shock Protein 90 (Hsp90) and Cell Division Cycle 37 as Orally Active Inhibitors for the Treatment of Colorectal Cancer
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69. FK506 Binding Protein 8 Peptidylprolyl Isomerase Activity Manages a Late Stage of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Folding and Stability
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70. Homoserine Toxicity in Saccharomyces cerevisiae and Candida albicans Homoserine Kinase ( thr1 Δ) Mutants
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71. Inhibition of FLT3 Expression by Green Tea Catechins in FLT3 Mutated-AML Cells
    Bùi Thị Kim Lý, Hoàng Thanh, Makoto Yamagishi, Yasuhiko Kano, Yukihiko Hara, Kazumi Nakano, Yuko Sato, Toshiki Watanabe · 2013 · PLoS ONE
72. Hsp90 Regulates Nongenetic Variation in Response to Environmental Stress
    Yu-Ying Phoebe Hsieh, Po-Hsiang Hung, Jun‐Yi Leu · 2013 · Molecular Cell
73. Chaperone Function of Hgh1 in the Biogenesis of Eukaryotic Elongation Factor 2
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74. An Hsp90 co-chaperone protein in yeast is functionally replaced by site-specific posttranslational modification in humans
    Abbey D. Zuehlke, Michael J. Reidy, Coney P. C. Lin, Paul LaPointe, Sarah Alsomairy, D. Joshua Lee, Génesis M. Rivera-Márquez, Kristin E. Beebe, Thomas L. Prince, Sunmin Lee et al. · 2017 · Nature Communications
75. A genomic approach highlights common and diverse effects and determinants of susceptibility on the yeast Saccharomyces cerevisiae exposed to distinct antimicrobial peptides
    Belén López‐García, Mónica Gandía, Alberto Muñoz, Lourdes Carmona, José F. Marcos · 2010 · BMC Microbiology
76. Hsp90 can accommodate the simultaneous binding of the FKBP52 and HOP proteins
    Hildenbrand, Zacariah L., Molugu, Sudheer K., Herrera, Nadia, Ramirez, Citlally, Xiao, Chuan, Bernal, Ricardo A. · 2011 · Oncotarget
77. A methylated lysine is a switch point for conformational communication in the chaperone Hsp90
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78. Differential Modulation of Functional Dynamics and Allosteric Interactions in the Hsp90-Cochaperone Complexes with p23 and Aha1: A Computational Study
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79. Allosteric Regulation of the Hsp90 Dynamics and Stability by Client Recruiter Cochaperones: Protein Structure Network Modeling
    Kristin M. Blacklock, Gennady M. Verkhivker · 2014 · PLoS ONE
80. Chaperoning STAT3/5 by Heat Shock Proteins: Interest of Their Targeting in Cancer Therapy
    Gaëtan Jégo, François Hermetet, François Girodon, Carmen Garrido · 2019 · Cancers
81. Aspergillus fumigatus Hsp90 interacts with the main components of the cell wall integrity pathway and cooperates in heat shock and cell wall stress adaptation
    Marina Campos Rocha, Karine Minari, João Henrique Tadini Marilhano Fabri, Joshua D. Kerkaert, Lisandra M. Gava, Anderson Ferreira da Cunha, Robert A. Cramer, Júlio C. Borges, Iran Malavazi · 2020 · Cellular Microbiology
82. Expanding the cellular molecular chaperone network through the ubiquitous cochaperones
    Frank Echtenkamp, Brian Freeman · 2011 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
83. Complementary α-arrestin-ubiquitin ligase complexes control nutrient transporter endocytosis in response to amino acids
    Vasyl A. Ivashov, Johannes Zimmer, Sinead Schwabl, Jennifer Kahlhofer, Sabine Weys, Ronald Gstir, Thomas A. E. Jakschitz, Leopold Kremser, Günther K. Bonn, Herbert H. Lindner et al. · 2020 · eLife
84. Drosophila Glycoprotein 93 Is an Ortholog of Mammalian Heat Shock Protein gp96 (grp94, HSP90b1, HSPC4) and Retains Disulfide Bond-Independent Chaperone Function for TLRs and Integrins
    Crystal Morales, Shuang Wu, Yi Yang, Bing Hao, Zihai Li · 2009 · The Journal of Immunology
85. Hsp90 Co-chaperones Form Plastic Genetic Networks Adapted to Client Maturation
    Maximilian M. Biebl, Maximilian Riedl, Johannes Büchner · 2020 · Cell Reports
86. Interplay between Chaperones and Protein Disorder Promotes the Evolution of Protein Networks
    Sebastian Pechmann, Judith Frydman · 2014 · PLoS Computational Biology
87. Molecular mechanism of cytotoxicity induced by Hsp90-targeted Antp-TPR hybrid peptide in glioblastoma cells
    Tomohisa Horibe, Aya Torisawa, Masayuki Kohno, Koji Kawakami · 2012 · Molecular Cancer
88. Chaperoning the Chaperone: A Role for the Co-chaperone Cpr7 in Modulating Hsp90 Function in Saccharomyces cerevisiae
    Abbey D. Zuehlke, Jill L. Johnson · 2012 · Genetics
89. Incapacitating the evolutionary capacitor: Hsp90 modulation of disease
    Patricia L. Yeyati, Veronica van Heyningen · 2008 · Current Opinion in Genetics & Development
90. TRAP1: a viable therapeutic target for future cancer treatments?
    Giacomo Lettini, Francesca Maddalena, Lorenza Sisinni, Valentina Condelli, Danilo Swann Matassa, Maria Paola Costi, Daniele Simoni, Franca Esposito, Matteo Landriscina · 2017 · Expert Opinion on Therapeutic Targets
91. Identification of Novel Response and Predictive Biomarkers to Hsp90 Inhibitors Through Proteomic Profiling of Patient-derived Prostate Tumor Explants
    Elizabeth V. Nguyen, Margaret M. Centenera, Max V. Moldovan, Rajdeep Das, Swati Irani, Andrew D. Vincent, Howard Chan, Lisa Glen Horvath, David John Lynn, Roger J. Daly et al. · 2018 · Molecular & Cellular Proteomics
92. Heterologous Hsp90 promotes phenotypic diversity through network evolution
    Tracy Chih-Ting Koubková-Yu, Jung-Chi Chao, Jun‐Yi Leu · 2018 · PLoS Biology
93. HSP90 and Its Novel Co-Chaperones, SGT1 and CHP-1, in Brain of Patients with Parkinson’s Disease and Dementia with Lewy Bodies
    Anastasiia Bohush, Grażyna Niewiadomska, Serge Weis, Anna Filipek · 2019 · Journal of Parkinson s Disease
94. Cdc37 (Cell Division Cycle 37) Restricts Hsp90 (Heat Shock Protein 90) Motility by Interaction with N-terminal and Middle Domain Binding Sites
    Julia M. Eckl, Daniel Andreas Rutz, Veronika Haslbeck, Bettina K. Zierer, Jochen Reinstein, Klaus Richter · 2013 · Journal of Biological Chemistry
95. Modulation of Human Hsp90α Conformational Dynamics by Allosteric Ligand Interaction at the C-Terminal Domain
    David L. Penkler, Özlem Taştan Bishop · 2019 · Scientific Reports
96. PIH1D1, a subunit of R2TP complex, inhibits doxorubicin-induced apoptosis
    Mika Inoue, Makio Saeki, Hiroshi Egusa, Hitoshi Niwa, Yoshinori Kamisaki · 2010 · Biochemical and Biophysical Research Communications
97. Targeting protein-protein interactions in drug discovery: Modulators approved or in clinical trials for cancer treatment
    Cristina Camps-Fajol, Debora Cavero, Jordi Minguillón, Jordi Surrallés · 2024 · Pharmacological Research
98. Atomistic simulations and network-based modeling of the Hsp90-Cdc37 chaperone binding with Cdk4 client protein: A mechanism of chaperoning kinase clients by exploiting weak spots of intrinsically dynamic kinase domains
    Josh Czemeres, Kurt Buse, Gennady M. Verkhivker · 2017 · PLoS ONE
99. Heterozygous Yeast Deletion Collection Screens Reveal Essential Targets of Hsp90
    Eric A. Franzosa, Véronique Albanèse, Judith Frydman, Yu Xia, Amie Jo McClellan · 2011 · PLoS ONE
100. Geraniin selectively promotes cytostasis and apoptosis in human colorectal cancer cells by inducing catastrophic chromosomal instability
     Xihan Guo, Han Wang, Juan Ni, Ziqing Liang, Xiayu Wu, Jinglun Xue, Xu Wang · 2018 · Mutagenesis