Hematopoietic Stem Cells Reversibly Switch from Dormancy to Self-Renewal during Homeostasis and Repair

Wilson, Anne, Laurenti, Elisa, Oser, Gabriela, van der Wath, Richard C., Blanco-Bose, William, Jaworski, Maike, Offner, Sandra, Dunant, Cyrille F., Eshkind, Leonid, Bockamp, Ernesto, Lió, Pietro, MacDonald, H. Robson, Trumpp, Andreas·2008·Cell

DOI 10.1016/j.cell.2008.10.048

Cited by (1,004)

Items 301–400 of 1,004

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Carsten Riether, Christian M. Schürch, Christoph Flury, Magdalena Hinterbrandner, Linda Drück, Anne-Laure Huguenin, Gabriela Maria Baerlocher, Ramin Radpour, Adrian F. Ochsenbein · 2015 · Science Translational Medicine
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Ingmar Glauche, Kateri Ann Moore, Lars Thielecke, Katrin Horn, Markus Loeffler, Ingo Roeder · 2009 · PLoS Computational Biology
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Bilal N. Sheikh, Yuqing Yang, Jaring Schreuder, Susan K. Nilsson, Rebecca A. Bilardi, Sebastian Carotta, Helen M. McRae, Donald Metcalf, Anne Kathrin Voss, Tim Thomas · 2016 · Blood
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Keunhee Oh, Sae Rom Kim, Dae‐Kyum Kim, Myung Won Seo, Changjin Lee, Hak Mo Lee, Ju-Eun Oh, Eun Young Choi, Dong‐Sup Lee, Yong Song Gho et al. · 2015 · ACS Nano
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Katharina Schönberger, Nadine Obier, Mari Carmen Romero-Mulero, Pierre Cauchy, Julian Mess, Polina V. Pavlovich, Yu Wei Zhang, Michael Mitterer, Jasmin Rettkowski, Maria‐Eleni Lalioti et al. · 2021 · Cell stem cell
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Julie Lacombe, Sabine Herblot, Shanti Rojas‐Sutterlin, André Haman, Stéphane Barakat, Norman N. Iscove, Guy Sauvageau, T Hoang · 2009 · Blood
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Erin Nevius, Ana Cordeiro Gomes, João P. Pereira · 2015 · Clinical Reviews in Allergy & Immunology
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Reinhard Obst · 2015 · Frontiers in Immunology
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Oleg F. Kandarakov, Alexander V. Belyavsky, Ekaterina Semenova · 2022 · International Journal of Molecular Sciences
Adult blood stem cell localization reflects the abundance of reported bone marrow niche cell types and their combinations
Konstantinos D. Kokkaliaris, Leo Kunz, Nina Cabezas‐Wallscheid, Constantina Christodoulou, Simon Renders, Fernando D. Camargo, Andreas Trumpp, David T. Scadden, Timm Schroeder · 2020 · Blood
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Stephen B. Ting, Éric Deneault, Kristin J. Hope, Sonia Cellot, Jalila Chagraoui, Nadine Mayotte, Jonas F. Dorn, Jean‐Philippe Laverdure, Michael Harvey, Edwin D. Hawkins et al. · 2011 · Blood
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Peter J. Quesenberry, Mark S. Dooner, Jason M. Aliotta · 2010 · Experimental Hematology
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Warr, Matthew R., Pietras, Eric M., Passegué, Emmanuelle · 2011 · WIREs Systems Biology and Medicine
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Amélie Rezza, Rachel Sennett, Michael Rendl · 2014 · Current topics in developmental biology/Current Topics in Developmental Biology
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Anastasia Lomova, Danielle N. Clark, Beatriz Campo-Fernández, Carmen Flores, Michael L. Kaufman, Sorel T. Fitz‐Gibbon, Xiaoyan Wang, Eric Miyahira, Devin Brown, Mark A. DeWitt et al. · 2018 · Stem Cells
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E.L. Davies, Erin L. Davies · 2008 · Cold Spring Harbor Symposia on Quantitative Biology
Slow-cycling/quiescence balance of hematopoietic stem cells is related to physiological gradient of oxygen
Amélie Valérie Guitart, Mohammad Hammoud, Persio Dello Sbarba, Zoran Ivanović, Vincent Praloran · 2010 · Experimental Hematology
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Thomas Höfer, Hans-Reimer Rodewald · 2018 · Blood
BMP signaling mediates glioma stem cell quiescence and confers treatment resistance in glioblastoma
Rohit Sachdeva, Megan Wu, Kevin C. Johnson, Hyunsoo Kim, Angela Celebre, Uswa Shahzad, Maya Srikanth Graham, John A. Kessler, Jeffrey H. Chuang, Jason Karamchandani et al. · 2019 · Scientific Reports
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Scaramozza, Annarita, Park, Dongsu, Kollu, Swapna, Beerman, Isabel, Sun, Xuefeng, Rossi, Derrick J., Lin, Charles P., Scadden, David T., Crist, Colin, Brack, Andrew S. · 2019 · Cell Stem Cell
Hematopoietic stem cell fate through metabolic control
Kyoko Ito, Keisuke Ito · 2018 · Experimental Hematology
Ex Vivo Expansion of Hematopoietic Stem Cells for Therapeutic Purposes: Lessons from Development and the Niche
Parisa Tajer, Karin Pike‐Overzet, Sagrario Arias, Menzo J E Havenga, Frank J. T. Staal · 2019 · Cells
Do haematopoietic stem cells age?
Kenneth A Dorshkind, Thomas Höfer, Encarnacion Montecino‐Rodriguez, Peter D. Pioli, Hans-Reimer Rodewald · 2019 · Nature reviews. Immunology
Autophagy in acute leukemias: A double-edged sword with important therapeutic implications
Cecilia Evangelisti, Camilla Evangelisti, Francesca Chiarini, Annalisa Lonetti, Francesca Buontempo, Luca Maria Neri, James Andrew McCubrey, Alberto Maria Martelli · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
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Barbara Gayraud-Morel, Fabrice C Chrétien, Aurélie Jory, Ramkumar Sambasivan, Elisa Négroni, Patricia Flamant, Guillaume Soubigou, Jean‐Yves Coppée, James P. Di Santo, Ana Cumano et al. · 2012 · Journal of Cell Science
Diet‐induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow
Susan M. van den Berg, Tom T. P. Seijkens, Pascal J. H. Kusters, Linda Beckers, Myrthe den Toom, Esther Smeets, Johannes H.M. Levels, Menno P.J. de Winther, Esther Lutgens · 2016 · The FASEB Journal
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Chavez, James S., Rabe, Jennifer L., Loeffler, Dirk, Higa, Kelly C., Hernandez, Giovanny, Mills, Taylor S., Ahmed, Nouraiz, Gessner, Rachel L., Ke, Zhonghe, Idler, Beau M. et al. · 2021 · Journal of Experimental Medicine
Lineage tracing of murine adult hematopoietic stem cells reveals active contribution to steady-state hematopoiesis
Chapple, Richard H., Tseng, Yu-Jung, Hu, Tianyuan, Kitano, Ayumi, Takeichi, Makiko, Hoegenauer, Kevin A., Nakada, Daisuke · 2018 · Blood Advances
Metastatic cancer stem cells: from the concept to therapeutics.
Wenting Liao, Yaping Ye, Yong‐Jian Deng, Xiu‐Wu Bian, Yan-qing Ding · 2014 · Europe PMC (PubMed Central)
FLT3-ITD Knockin Impairs Hematopoietic Stem Cell Quiescence/Homeostasis, Leading to Myeloproliferative Neoplasm
S. Haihua Chu, Diane Heiser, Li Li, Ian M. Kaplan, Michael I. Collector, David L. Huso, Saul J. Sharkis, Curt I. Civin, Don Small · 2012 · Cell stem cell
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Tatyana Grinenko, Anne Eugster, Lars Thielecke, Beáta Ramasz, Anja Krüger, Sevina Dietz, Ingmar Glauche, Alexander Gerbaulet, Malte v. Bonin, Onur Başak et al. · 2018 · Nature Communications
Hallmarks of stemness in mammalian tissues
Joep Beumer, Hans C. Clevers · 2024 · Cell stem cell
Mobilization and Homing of Hematopoietic Stem Cells
Beatriz Suárez-Álvarez, Antonio López‐Vázquez, Carlos López‐Larrea · 2012 · Advances in experimental medicine and biology
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Papia Chakraborty, F. William Buaas, Manju Sharma, Elizabeth M. Snyder, Dirk G. de Rooij, Robert E. Braun · 2013 · Stem Cells
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Jaclyn Andricovich, Kai Yan, Weiqun Peng, Adlen Foudi, Alexandros Tzatsos · 2016 · Journal of Clinical Investigation
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Mihaela Crisan, Elaine Anne Dzierzak · 2016 · Development
Hematopoiesis in numbers
Jason Cosgrove, Lucie Hustin, Rob J. de Boer, Leïla Perié · 2021 · Trends in Immunology
The role of novel and known extracellular matrix and adhesion molecules in the homeostatic and regenerative bone marrow microenvironment
Sofieke Klamer, Carlijn Voermans · 2014 · Cell Adhesion & Migration
Kit-Shp2-Kit signaling acts to maintain a functional hematopoietic stem and progenitor cell pool
Helen He Zhu, Kaihong Ji, Nazilla B. Alderson, Zhao He, Shuangwei Li, Wen Liu, Dong‐Er Zhang, Linheng Li, Gen‐Sheng Feng · 2011 · Blood
Immunomodulating and Immunoresistance Properties of Cancer-Initiating Cells: Implications for the Clinical Success of Immunotherapy
Cristina Maccalli, Giorgio Parmiani, Soldano Ferrone · 2017 · Immunological Investigations
Niche derived netrin-1 regulates hematopoietic stem cell dormancy via its receptor neogenin-1
Simon Renders, Arthur Flohr Svendsen, Jasper Panten, Nicolas Rama, Maria Maryanovich, Pia Sommerkamp, Luisa Ladel, Anna Rita Redavid, Benjamin Gibert, Seka Lazare et al. · 2021 · Nature Communications
HectD1 controls hematopoietic stem cell regeneration by coordinating ribosome assembly and protein synthesis
Kaosheng Lv, Chujie Gong, Charles Antony A, Xu Han, Jian‐Gang Ren, Ryan Donaghy, Ying Cheng, Simone Pellegrino, Alan John Warren, Vikram R. Paralkar et al. · 2021 · Cell stem cell