Regulation of Translation Initiation in Eukaryotes: Mechanisms and Biological Targets

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Items 1,001–1,050 of 1,050

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    Yee-Han Chan, Kong Yen Liew, Kamal Rullah, H. Harith, Ji-Wei Tan, D. Israf, K. Shaari, Mexmollen Marcus, C. Tham · 2025 · Naunyn-Schmiedeberg's Archives of Pharmacology
  2. Cycloheximide resistant ribosomes reveal adaptive translation dynamics in C. elegans
    Qiuxia Zhao, B. Bolton, Reed Rothe, Reiko Tachibana, Can Cenik, Elif Sarinay Cenik · 2025 · Genetics
  3. TOB Proteins Repress Translation via the CCR4–NOT Deadenylase Complex Independent of Deadenylation
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  5. BLF1 Affects ATP Hydrolysis Catalyzed by Native and Mutated eIF4A1 and eIF4A2 Proteins
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  8. Evaluating the Impact of Variants on Translation Initiation Sites for Accurate Identification of Functional Open Reading Frames (ORFs)
    Thanos Lakes, V. Efstathiou, Nikos Perdikopanis · 2024 · IEEE International Conference on Bioinformatics and Biomedicine
  9. Scalable Synthesis of an Acid Stable Analogue of Hippuristanol.
    Ellen MacDonald, Peter Blencowe, Jennifer Baker, Charlotte Bennett, S. Boyd, K. Fowler, Laurent Rigoreau, Emma Stanway, Morag Watson, Hai-Bin Mao et al. · 2024 · Organic Letters
  10. Investigation of COVID-19 virus mutagenicity and the effect of the NSP13, NSP14, and NSP16 on the -1 ribosomal frameshifting
    Ali Khanifar, Azin Najafi, Jaber Hemmati, Fatemeh Nouri, Seyed Ali Hosseini, Mohammad Taheri · 2024 · Frontiers in Virology
  11. Ribosome decision graphs for the representation of eukaryotic RNA translation complexity
    Jack A. S. Tierney, Michał I. Świrski, Håkon Tjeldnes, Jonathan M. Mudge, Joanna Kufel, Nicola Whiffin, Eivind Valen, Pavel V. Baranov · 2024 · Genome Research
  12. RNA Activators of Stress Kinase PKR within Human Genes That Control Splicing or Translation Create Novel Targets for Hereditary Diseases
    Raymond Kaempfer · 2024 · International Journal of Molecular Sciences
  13. Intermolecular base‐pairing interactions, a unique topology and exoribonuclease‐resistant noncoding RNAs drive formation of viral chimeric RNAs in plants
    Katalin Nemes, Jose Fernando Gil, Sebastian Liebe, Mansi Mansi, Efstratia Poimenopoulou, Britt‐Louise Lennefors, Mark Varrelmann, Eugene I. Savenkov · 2023 · New Phytologist
  14. Editorial: RNA machines
    Nikolay E. Shirokikh, Kirk B. Jensen, Nehal Thakor · 2023 · Frontiers in Genetics
  15. Prefrontal cortex proteomic alteration after social instability stress in adolescents rats
    Evelyn C. S. Santos, Ana Filipa Terceiro, Rui Miguel Pinheiro Vitorino, Igor Moreira Lopes, Renata L. Alves, João Bettencourt Relvas, Teresa Summavielle, Ana Magalhães · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  16. Mathematical modelling of non-feedback and feedback modes within eIF2 machinery: Limited data aided with well-studied in-vivo system of yeast
    M. F. Khan, Mohammad Mursaleen · 2023 · 2023 International Conference on Computational Intelligence and Sustainable Engineering Solutions (CISES)
  17. Positive Regulation of Splicing of Cellular and Viral mRNA by Intragenic RNA Elements That Activate the Stress Kinase PKR, an Antiviral Mechanism
    Raymond O.R. Kaempfer · 2023 · Genes
  18. Coronavirus endoribonuclease nsp15 induces host cellular protein synthesis shutoff
    Xiao-Qian Gong, Shan Feng, Bo Gao, Shou-Guo Fang, Wen-Lian Weng, Wen-Xiang Xue, Hong-Yan Chu, Yan-Mei Yuan, Yu-Qiang Cheng, Ying-Jie Sun et al. · 2023 · bioRxiv
  19. The nutrient-sensing GCN2 signaling pathway is essential for circadian clock function by regulating histone acetylation under amino acid starvation
    Xiao-Lan Liu, Yu-Lin Yang, Yue Hu, Jingjing Wu, Chu-Qiao Han, Xihui Gan, Qiaojia Lu, Shaohua Qi, Jin-Hu Guo, Qun He et al. · 2022 · bioRxiv
  20. A retrograde GCN2/eIF2α, but ATF4 independent, mechanism maintains synaptic strength under acute amino acid scarcity at the NMJ
    Grant Kauwe, Megumi Mori, Edward H. Liao, G. Scott, A. Haghighi · 2022 · bioRxiv
  21. Protein expression and purification protein expression and purification, molecular interaction, and X-ray crystallographic analysis of baculovirus protein PK2.
    D. Takeshita · 2022 · Protein Expression and Purification
  22. Genome-wide regulatory effects of STRs stabilized by elevated expression of antioxidant genes in C. elegans
    Gaotian Zhang, Erik C. Andersen · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  23. Head and Neck Cancer-derived small extracellular vesicles sensitize TRPV1+ neurons to mediate cancer pain
    Kufreobong E. Inyang, Christine M. Evans, Matthew Heussner, M. Petroff, M. Reimers, P. Vermeer, Nathan Tykocki, J. Folger, G. Laumet · 2022 · bioRxiv
  24. Initiator tRNA lacking 1-methyladenosine is unexpectedly targeted by the rapid tRNA decay pathway in evolutionarily distant yeast species
    Monika Tasak, E. Phizicky · 2022 · bioRxiv
  25. ZNF598 responds to mitochondrial stress to abort stalled translation on mitochondrial outer membrane and maintain tissue homeostasis
    Jinzhu Geng, Yu Li, Zhi-Hao Wu, Rani Ohja, Shuangxi Li, Bing-Wei Lu · 2022 · bioRxiv
  26. Transcriptome Analysis of the Nematode Caenorhabditis elegans and Litoditis marina in a Chemically Defined Food Environment
    Peiqi Sun, Xuwen Cao, Liusuo Zhang · 2022 · bioRxiv
  27. Ribosome changes elicit non-canonical translation for chemosurvival in G0 leukemic cells
    C. Datta, S. Truesdell, S. Bukhari, H. Ngue, B. Buchanan, Ke Wu, O. Le Tonqueze, S. Lee, M. Granovetter, M. Boukhali et al. · 2021 · bioRxiv
  28. Target of Rapamycin drives unequal responses to essential amino acid depletion in egg laying
    A. N. Alves, C. Sgrò, Matthew W. D. Piper, C. Mirth · 2021
  29. ­ Functional Characterization of 5’ UTR Cis-Acting Sequence Elements That Modulate Translational Efficiency in P. Falciparum and Humans
    Valentina E. Garcia, Rebekah L. Dial, J. Derisi · 2021
  30. A specific eIF4A paralog facilitates LARP1-mediated translation repression during mTORC1 inhibition
    Yuichi Shichino, Mari Mito, Kazuhiro Kashiwagi, Mari Takahashi, Takuhiro Ito, Nicholas T. Ingolia, Shintaro Iwasaki · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  31. Functional characterization of 5’ UTR cis-acting sequence elements that modulate translational efficiency in P. falciparum and humans
    Valentina E. Garcia, Rebekah L. Dial, J. Derisi · 2021 · bioRxiv
  32. Tandem repeats ubiquitously flank and select translation initiation sites.
    Ali M. A. Maddi, Kaveh Kavousi, Masoud Arabfard, Hamid Ohadi, Mina Ohadi · 2021 · Research Square
  33. Inhibition of Mul1-mediated ubiquitination promotes mitochondria-associated translation
    Yuan Gao, M. Cardamone, Julian Kwan, Joseph Orofino, R. Hekman, Shawn M. Lyons, A. Emili, Valentina Perissi · 2021 · bioRxiv
  34. Дофаминовый нейротрофический фактор мозга (CDNF): структура, функции и терапевтический потенциал
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  35. A protein-trap allele reveals roles for Drosophila ATF4 in photoreceptor degeneration, oocyte maturation and wing development
    Deepika Vasudevan, Hidetaka Katow, Grace Tang, H. Ryoo · 2021 · bioRxiv
  36. Decreased HECTD1 mRNA expression is associated with poor prognosis and enhanced mitochondrial cellular respiratory function in breast cancer
    Yasuaki Uemoto, E. Katsuta, Naoto Kondo, Y. Wanifuchi-Endo, T. Fujita, Tomoko Asano, T. Hisada, M. Terada, Akiko Kato, K. Okuda et al. · 2021
  37. The CTEXT complex in Saccharomyces cerevisiae plays a crucial role in degrading distinct sets of aberrant mRNAs by the nuclear exosome
    Upasana Saha, Rajlaxmi Gaine, Sunirmal Paira, Satarupa Das, Biswadip Das · 2021 · bioRxiv
  38. A novel type of IRES having variable numbers of eIF4E-binding site and synergistic effect in RNA2 of WYMV isolates
    Guo-Wei Geng, Cheng-Ming Yu, Xiang-Dong Li, Ke-Rong Shi, Xue-Feng Yuan · 2021 · bioRxiv
  39. Pharmacological inhibition of LSD1 triggers myeloid differentiation by targeting GSE1, a novel oncogene in AML
    L. Nicosia, F. Boffo, E. Ceccacci, I. Pallavicini, Fabio Bedin, Enrico Massignani, R. Ravasio, S. Minucci, T. Bonaldi · 2021 · bioRxiv
  40. Paip2 associates with PABPC1 on mRNA, and may facilitate PABPC1 dissociation from mRNA upon deadenylation
    Jing-Wei Xie, Xiaoyu Wei, G. Kozlov, Y. Chen, Marie Ménade · 2021 · bioRxiv
  41. Upregulation of eIF4E, but not other translation initiation factors, in dendritic spines during memory consolidation
    S. Gindina, Benjamin Botsford, K. Cowansage, Joseph E LeDoux, E. Klann, Charles A. Hoeffer, Linnaea E. Ostroff · 2021 · bioRxiv
  42. Roles Of HIF and 2-Oxoglutarate Dependent Enzymes in Controlling Gene Expression In Hypoxia
    Julianty Frost, M. Frost, Michael Batie, Hao Jiang, S. Rocha · 2020
  43. Lifespan Regulation by Insulin Signaling Through Phosphorylation of Proteins Beyond FOXO
    Wen-Jun Li, Li Tao, Chen-Wei Wang, Yong-Hong Yan, Mei-Jun Zhang, Ze-Xian Liu, Yu-Xin Li, Hanqing Zhao, Xue-Mei Li, Xian-Dong He et al. · 2020
  44. Obestatin signaling controls Schwann cells and axonal transport to counteract neuromuscular synaptic loss in skeletal muscle
    J. Camiña, A. Sánchez-Temprano, S. Leal-Lopez, Jessica González-Sánchez, C. S. Mosteiro, R. Gallego, J. Relova, Y. Pazos · 2020
  45. Multivalent interactions between eIF4G1, Pub1 and Pab1 drive the formation of protein condensates
    B. Chaves-Arquero, S. Martínez-Lumbreras, N. Sibille, S. Camero, P. Bernadó, M. Jiménez, S. Zorrilla, J. Pérez-Cañadillas · 2020
  46. A prion accelerates proliferation at the expense of lifespan
    David M. Garcia, E. Campbell, Christopher M. Jakobson, Mitsuhiro Tsuchiya, Acadia L. DiNardo, M. Kaeberlein, Dan Jarosz · 2020 · bioRxiv
  47. Mitochondria Controlled mTORC1 Activation Compartmentalizes Translation Initiation Factor eIF4E to Augment Intracellular Trafficking and Extracellular Export of miRNA in Mammalian Cells
    Susanta Chatterjee, Yogaditya Chakrabarty, Saikat Banerjee, Souvik Ghosh, S. Bhattacharyya · 2020 · bioRxiv
  48. Investigation of mTOR-independent regulation of macroautophagy
    Richard I. Odle · 2020
  49. Role of CDK1 in Translational Regulation in the M-Phase
    J. Kalous, Denisa Jansová, A. Šušor · 2020
  50. Defining the molecular determinants required for RNA binding functions of the Bicaudal‐C (Bicc1) translational repressor protein
    Sonam Dolma, Tomasso Tonelli, Megan E. Dowdle, M. Sheets · 2020 · The FASEB Journal