Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol

Edlich, Frank, Banerjee, Soojay, Suzuki, Motoshi, Cleland, Megan M., Arnoult, Damien, Wang, Chunxin, Neutzner, Albert, Tjandra, Nico +1 more·2011·Cell

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  2. miR‐125b lowers sensitivity to apoptosis following mitotic arrest: Implications for breast cancer therapy
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  3. γ-Rays-generated ROS induce apoptosis via mitochondrial and cell cycle alteration in smooth muscle cells
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  8. Bax mitochondrial relocation is linked to its phosphorylation and its interaction with Bcl-xL
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  10. Tiron and trolox potentiate the autophagic cell death induced by magnolol analog Ery5 by activation of Bax in HL-60 cells
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  12. How Do Hexokinases Inhibit Receptor-Mediated Apoptosis?
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  13. Understanding sensitivity to BH3 mimetics: ABT-737 as a case study to foresee the complexities of personalized medicine
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  14. Aplysin Protects Against Alcohol‐Induced Liver Injury Via Alleviating Oxidative Damage and Modulating Endogenous Apoptosis‐Related Genes Expression in Rats
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  15. Lipid-modulation of membrane insertion and refolding of the apoptotic inhibitor Bcl-xL
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  16. Mitochondria and Chloroplasts Shared in Animal and Plant Tissues: Significance of Communication
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  17. Norcantharidin triggers apoptotic cell death in non-small cell lung cancer via a mitophagy-mediated autophagy pathway
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  18. β-elemene acts as an antitumor factor and downregulates the expression of survivin, Bcl-xL and Mta-1
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  19. Transient apoptosis inhibition in donor stem cells improves hematopoietic stem cell transplantation
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  20. N-terminal acetylation modulates Bax targeting to mitochondria
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  21. Prompt apoptotic response to high glucose in SGLT-expressing renal cells
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  22. Yeast as a tool for studying proteins of the Bcl-2 family
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  23. Senolysis by ABT-263 is associated with inherent apoptotic dependence of cancer cells derived from the non-senescent state
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  25. Organophosphates Induced Alzheimer's Disease: An Epigenetic Aspect
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  26. BFL1 modulates apoptosis at the membrane level through a bifunctional and multimodal mechanism showing key differences with BCLXL
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  27. Intrinsically Connected: Therapeutically Targeting the Cathepsin Proteases and the Bcl-2 Family of Protein Substrates as Co-regulators of Apoptosis
    Surinder M. Soond, Maria V. Kozhevnikova, Lyudmila V. Savvateeva, Paul A. Townsend, Andrey A. Zamyatnin · 2021 · International Journal of Molecular Sciences
  28. The substitution of Proline 168 favors Bax oligomerization and stimulates its interaction with LUVs and mitochondria
    Lilit Simonyan, Alexandre Légiot, Ioan Lascu, Grégory Durand, Marie‐France Giraud, Cécile Dahout-Gonzalez, Stéphen Manon · 2017 · Biochimica et Biophysica Acta (BBA) - Biomembranes
  29. A switchable ceramide transfer protein for dissecting the mechanism of ceramide‐induced mitochondrial apoptosis
    Amrita Jain, Shashank Dadsena, Joost C. M. Holthuis · 2020 · FEBS Letters
  30. Analysis of the Binding Sites on BAX and the Mechanism of BAX Activators through Extensive Molecular Dynamics Simulations
    Guoqin Feng, Xiangying Zhang, Yan Li, Renxiao Wang · 2021 · Journal of Chemical Information and Modeling
  31. Synergism of a novel MCL‑1 downregulator, acriflavine, with navitoclax (ABT‑263) in triple‑negative breast cancer, lung adenocarcinoma and glioblastoma multiforme
    Anbok Lee, Hyeon‐Ok Jin, Md. Masudul Haque, Hee Yeon Kim, Hana Jung, Jin G. Park, Ilwhan Kim, Joo Young Song, Hye Kyoung Yoon, Hyoung Kim et al. · 2021 · International Journal of Oncology
  32. The effect of lipocalin-2 (LCN2) on apoptosis: a proteomics analysis study in an LCN2 deficient mouse model
    Dongming Wu, Xiaopeng Wang, Ye Han, Yayun Wang · 2021 · BMC Genomics
  33. Identification of PANoptosis-related signature reveals immune infiltration characteristics and immunotherapy responses for renal cell carcinoma
    Yan Xu, Jingqi Hua, Hongliang Que, Tengyue Zeng, Quan Li, Junpeng Deng, Jian‐Jun Xie · 2024 · BMC Cancer
  34. Gasdermins in Apoptosis: New players in an Old Game.
    Corey Rogers, Emad S. Alnemri · 2019 · Europe PMC (PubMed Central)
  35. Key residues in the VDAC2-BAK complex can be targeted to modulate apoptosis
    Zhengwei Yuan, Mark F. van Delft, Xiang Li, Fransisca Sumardy, Brian James Smith, David C.S. Huang, Guillaume Lessène, Yelena Khakam, Ruitao Jin, Sitong He et al. · 2024 · PLoS Biology
  36. The C-terminal sequences of Bcl-2 family proteins mediate interactions that regulate cell death
    Dang Quan Nguyen, Elizabeth J. Osterlund, Justin Kale, David William Andrews · 2024 · Biochemical Journal
  37. Further lead optimization on Bax activators: Design, synthesis and pharmacological evaluation of 2-fluoro-fluorene derivatives for the treatment of breast cancer
    Gang Liu, Hyejin Kim, Pingyuan Wang, Doerte R. Fricke, Haiying Chen, Tianzhi Wang, Qiang Shen, Jia Zhou · 2021 · European Journal of Medicinal Chemistry
  38. Pyrazine Moiety: Recent Developments in Cancer Treatment
    Rakesh Sahu, Kamal Shah, Yash Gautam, Kaushilya Sahu · 2023 · Current Organic Chemistry
  39. BAX activation in mouse retinal ganglion cells occurs in two temporally and mechanistically distinct steps
    Margaret E. Maes, Ryan Donahue, Cassandra L. Schlamp, Olivia J. Marola, Richard T. Libby, Robert W. Nickells · 2023 · Molecular Neurodegeneration
  40. The endoplasmic reticulum pool of Bcl-xL prevents cell death through IP3R-dependent calcium release
    Rudy Gadet, Lea Jabbour, Trang Thi Minh Nguyen, Olivier D. Lohez, Ivan Mikaélian, Philippe Gonzalo, Tomas Luyten, Mounira Chalabi‐Dchar, Anne Wierinckx, Olivier Marcillat et al. · 2024 · Cell Death Discovery
  41. BCL ‐2 Family of Proteins and Mammary Cellular Fate
    Monica Colitti · 2012 · Anatomia Histologia Embryologia
  42. Overexpression of DCF1 inhibits glioma through destruction of mitochondria and activation of apoptosis pathway
    Yuqiong Xie, Qiang Li, Qingbo Yang, Mei Yang, Zhifeng Zhang, Liucun Zhu, Yan Xin Huang, Ruili Feng, Shiqing Zhang, Chen Yu Huang et al. · 2014 · Scientific Reports
  43. 2-Bromopalmitate attenuates bone cancer pain via reversing mitochondrial fusion and fission imbalance in spinal astrocytes
    Wei Meng, Miaomiao Hao, Na Hee Yu, Mingyue Li, Jieqiong Ding, Banghua Wang, Haili Zhu, Min Xie · 2019 · Molecular Pain
  44. Huangqi decoction inhibits hyperglycemia-induced podocyte apoptosis by down-regulated Nox4/p53/Bax signaling in vitro and in vivo.
    Zezheng Li, Wenjuan Deng, Aili Cao, Yingjun Zang, Yunman Wang, Hao Wang, Li Wang, Wen Peng · 2019 · PubMed Central
  45. Ethanol extract of Ophiorrhiza pumila suppresses liver cancer cell proliferation and migration
    Hui Liu, Wanqin Liao, Lixia Fan, Zhaoguang Zheng, Dahai Liu, Qingwen Zhang, Anping Yang, Fang Liu · 2020 · Chinese Medicine
  46. Poxvirus antagonism of innate immunity by Bcl-2 fold proteins
    Edward Franklin, Amir Rafiq Khan · 2012 · Journal of Structural Biology
  47. PHLPP1 deficiency ameliorates cardiomyocyte death and cardiac dysfunction through inhibiting Mcl-1 degradation.
    Y. Tan, Tongxing Li, Mei-Ling Hu, Bo Wang, Qing-Qing Zhou, Yuyu Jiang, Shengqi Zhang, Xuewen Duan, Jun-Qi Yang, Xing-Guang Liu et al. · 2022 · Cellular Signalling
  48. Cell death classification: A new insight based on molecular mechanisms
    Sepehr Dehghan, Nasim Kheshtchin, Shaghayegh Hassannezhad, Maryam Soleimani · 2023 · Experimental Cell Research
  49. Targeting kinases that regulate programmed cell death: a new therapeutic strategy for breast cancer
    Yun Chul Hong, Jun He, Dan Deng, Qinyue Liu, Xuyu Zu, Yingying Shen · 2025 · Journal of Translational Medicine
  50. Integration and Oligomerization of Bax Protein in Lipid Bilayers Characterized by Single Molecule Fluorescence Study
    Luo, Lu, Yang, Jun, Liu, Dongxiang · 2014 · Journal of Biological Chemistry
  51. Differential regulation of BAX and BAK apoptotic activity revealed by small molecules
    Kaiming Li, Yu Q. Yap, Donia M. Moujalled, Fransisca Sumardy, Yelena Khakham, Angela Georgiou, Michelle Jahja, Thomas Eliot Lew, Melanie De Silva, Meng-Xiao Luo et al. · 2025 · Science Advances
  52. Protein Kinase-Mediated Decision Between the Life and Death
    Atilla Engin · 2021 · Advances in experimental medicine and biology
  53. Salmonella Infantis Delays the Death of Infected Epithelial Cells to Aggravate Bacterial Load by Intermittent Phosphorylation of Akt With SopB
    Bingxin Chu, Yanan Li, Ning Liu, Lanxin Yuan, Shiyan Chen, Yaohong Zhu, Jiufeng Wang · 2021 · Frontiers in Immunology
  54. Acetic acid triggers cytochrome c release in yeast heterologously expressing human Bax
    Joana P. Guedes, Vitória Baptista, Cátia Santos‐Pereira, Maria João Sousa, Stéphen Manon, Susana Rodrigues Chaves, Manuela Côrte‐Real · 2022 · APOPTOSIS
  55. Apoptotic mitochondrial poration by a growing list of pore‐forming BCL‐2 family proteins
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  56. Icariin prevents depression-like behaviors in chronic unpredictable mild stress-induced rats through Bax/cytoplasm C/caspase-3 axis to alleviate neuronal apoptosis
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  57. Aureusidin ameliorates 6-OHDA-induced neurotoxicity via activating Nrf2/HO-1 signaling pathway and preventing mitochondria-dependent apoptosis pathway in SH-SY5Y cells and Caenorhabditis elegans
    Kun Hu, Susu Zhu, Fanyu Wu, Yongzhen Zhang, Minyue Li, Ling Yuan, Wenjing Huang, Yichi Zhang, Jie Wang, Jie Ren et al. · 2023 · Chemico-Biological Interactions
  58. Counting on Death – Quantitative aspects of Bcl‐2 family regulation
    Annika Hantusch, Markus Rehm, Thomas Brunner · 2018 · FEBS Journal
  59. BCL-XL directly retrotranslocates the monomeric BAK
    Bin Wang, Zihao Mai, Mengyan Du, Lu Wang, Fangfang Yang, Yunyun Ma, Xiaoping Wang, Tongsheng Chen · 2019 · Cellular Signalling
  60. BAX and BAK become killers without a BH3 trigger
    Jerry M. Adams · 2019 · Cell Research
  61. Structure-based modeling of turnover of Bcl-2 family proteins bound to voltage-dependent anion channel 2 (VDAC2): Implications for the mechanisms of proapoptotic activation of Bak and Bax in vivo
    Hanna V. Dudko, V. A. Urban, Alexander I. Davidovskii, Valery G. Veresov · 2020 · Computational Biology and Chemistry
  62. Delivery of a Monomeric p53 Subdomain with Mitochondrial Targeting Signals from Pro-Apoptotic Bak or Bax
    Karina J. Matissek, Abood Okal, Mohanad Mossalam, Carol S. Lim · 2014 · Pharmaceutical Research
  63. Peptides Derived from the Transmembrane Domain of Bcl-2 Proteins as Potential Mitochondrial Priming Tools
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  64. Conformational States of the Cytoprotective Protein Bcl-xL
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  65. Modeling the function of BAX and BAK in early human brain development using iPSC-derived systems
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  66. Cell cycle progression and transmitotic apoptosis resistance promote escape from extrinsic apoptosis
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  67. Endoplasmic reticulum protein BIK binds to and inhibits mitochondria-localized antiapoptotic proteins
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  68. Mechanisms of cytotoxicity in six classes of ionic liquids: Evaluating cell cycle impact and genotoxic and apoptotic effects
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  69. The great migration of Bax and Bak
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  70. Hydroxycamptothecin mediates antiproliferative effects through apoptosis and autophagy in A549 cells
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  71. Role of Mitochondrial damage-associated molecular patterns in osteoarthritis: from pathogenesis, diagnosis, and prognosis to therapeutics
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  72. Bcl-xL inhibits tBid and Bax via distinct mechanisms
    Fabronia Murad, Ana J. García‐Sáez · 2020 · Faraday Discussions
  73. BCL-XL Overexpression Protects Pancreatic β-Cells against Cytokine- and Palmitate-Induced Apoptosis
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  74. Synergistic efficacy of a novel combination therapy controls growth of Bcl-xLbountiful neuroblastoma cells by increasing differentiation and apoptosis
    Nishant Mohan, Naren Lal Banik, Swapan K. Ray · 2011 · Cancer Biology & Therapy
  75. Mitochondrial E3 ubiquitin ligase MARCHF5 controls BAK apoptotic activity independently of BH3-only proteins
    Allan Shuai Huang, Hui San Chin, Boris Reljić, Tirta Mario Djajawi, Iris K. L. Tan, Jianan Gong, David A. Stroud, David C.S. Huang, Mark F. van Delft, Grant Dewson · 2022 · Cell Death and Differentiation
  76. Rejuvenating Bi(d)ology
    Sandra S. Zinkel, Xiao‐Ming Yin, Atan Gross · 2012 · Oncogene
  77. Bufalin induces apoptosis in the U-2OS human osteosarcoma cell line via triggering the mitochondrial pathway
    Ya Chen, MENG LI, ZHONGJI LI, Peng Gao, XIAO ZHOU, Jianxin Zhang · 2015 · Molecular Medicine Reports
  78. E2F1 interacts with BCL‐xL and regulates its subcellular localization dynamics to trigger cell death
    Céline Vuillier, Steven Lohard, Aurélie Fétiveau, Jennifer Allègre, Cémile Kayaci, Louise E King, Frédérique Braun, Sophie Barillé‐Nion, Fabien Gautier, Laurence Dubrez et al. · 2017 · EMBO Reports
  79. Imbalance deep multi‐instance learning for predicting isoform–isoform interactions
    Guoxian Yu, Jie Zeng, Jun Wang, Hong Zhang, Xiangliang Zhang, Maozu Guo · 2021 · International Journal of Intelligent Systems
  80. Computational design of BclxL inhibitors that target transmembrane domain interactions
    Gerard Duart, Assaf Elazar, Jonathan J. Weinstein, Laura Gadea‐Salom, Juan Ortiz‐Mateu, Sarel Jacob Fleishman, Ismael Mingarro, Luis Martínez‐Gil · 2023 · Proceedings of the National Academy of Sciences
  81. Disarib, a Specific BCL2 Inhibitor, Induces Apoptosis in Triple-Negative Breast Cancer Cells and Impedes Tumour Progression in Xenografts by Altering Mitochondria-Associated Processes
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  82. Changes in platelet Bax levels contribute to impaired platelet response to thrombin after cardiopulmonary bypass: prospective observational clinical and laboratory investigations
    M. Murase, Yoshinobu Nakayama, Daniel I. Sessler, Nanami Mukai, Satoru Ogawa, Yasufumi Nakajima · 2017 · British Journal of Anaesthesia
  83. Telomerase Reverse Transcriptase Contains a BH3-Like Motif and Interacts with BCL-2 Family Members.
    Young Jin, Long You, Hye Jeong Kim, Han‐Woong Lee · 2018 · Europe PMC (PubMed Central)
  84. Transcript-Level Dysregulation of BCL2 Family Genes in Acute Myeloblastic Leukemia
    Luiza Handschuh, Paweł Wojciechowski, Maciej Kaźmierczak, Krzysztof Lewandowski · 2021 · Cancers
  85. Royal jelly regulates the caspase, Bax and COX-2, TNF-α protein pathways in the fluoride exposed lung damage in rats
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  86. Blockade of the BAK Hydrophobic Groove by Inhibitory Phosphorylation Regulates Commitment to Apoptosis
    Abul Azad, Joanna L. Fox, Sabrina Leverrier, Alan Storey · 2012 · PLoS ONE
  87. Phosphorylation of Rad9 at Serine 328 by Cyclin A-Cdk2 Triggers Apoptosis via Interfering Bcl-xL
    Zhan Zhuo, Kan He, Dan Zhu, Dan Jiang, Yinghui Huang, Li Yang, Chao Sun, Ying‐Hua Jin · 2012 · PLoS ONE
  88. Designing combination therapies with modeling chaperoned machine learning
    Yin Zhang, Julie M. Huynh, Guan‐Sheng Liu, Richard Ballweg, Kayenat S Aryeh, Andrew L. Paek, Tongli Zhang · 2019 · PLoS Computational Biology
  89. Investigating Bax Subcellular Localization and Membrane Integration
    Grant Dewson · 2015 · Cold Spring Harbor Protocols
  90. DJ-1/PARK7 in Parkinson’s disease: mechanisms of pathogenesis and therapeutic potential
    Weicong Bao, Ying Ge, Juan Huang, Yuanyuan Li, Yong Luo, Nanqu Huang · 2025 · Neuroscience
  91. Differential evolution of signal-responsive RNA elements and upstream factors that control alternative splicing
    Jiuyong Xie · 2014 · Cellular and Molecular Life Sciences
  92. UBE2J1 knockdown promotes cell apoptosis in endometrial cancer via regulating PI3K/AKT and MDM2/p53 signaling
    Ping Zhang, Huiping Guo, Fang Zhao, Ke Jia, Fei Yang, Xiaoli Liu · 2023 · Open Medicine
  93. Ubiquitin-proteasome pathway-mediated regulation of the Bcl-2 family: effects and therapeutic approaches
    Galvin Le Qian Tang, Jolin Xiao Hui Lai, Shazib Pervaiz · 2023 · Haematologica
  94. Optimizing combination therapy in prostate cancer: mechanistic insights into the synergistic effects of Paclitaxel and Sulforaphane-induced apoptosis
    Tito N. Habib, Mohammed O. Altonsy, Salah A. Ghanem, Mohamed Salama, Mai Abd El Hafieth Hosny · 2024 · BMC Molecular and Cell Biology
  95. Recent advances in canonical versus non-canonical Ca2+-signaling-related anti-apoptotic Bcl-2 functions and prospects for cancer treatment
    Claire Cauwelier, Ian de Ridder, Geert Bultynck · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
  96. Inhibition of BAK-mediated apoptosis by the BH3-only protein BNIP5
    Sebastian Rühl, Zhenrui Li, Shagun Srivastava, Luigi Mari, Clifford S. Guy, Mao Yang, Tudor Moldoveanu, Douglas R. Green · 2024 · Cell Death and Differentiation
  97. Single-cell RNA-sequencing of BK polyomavirus replication in primary human renal proximal tubular epithelial cells identifies specific transcriptome signatures and a novel mitochondrial stress pattern
    Fabian H. Weissbach, Océane M. Follonier, Svenia Schmid, Karoline Leuzinger, Michael Schmid, Hans Hellmuth Hirsch · 2024 · Journal of Virology
  98. Apoptosis is Induced in Cancer Cells via the Mitochondrial Pathway by the Novel Xylocydine-Derived Compound JRS-15
    Chao Sun, Xiao-Xi Guo, Dan Zhu, Chuan Xiao, Xiao Feng Bai, Yang Li, Zhan Zhuo, Xianglong Li, Zhiguang Song, Ying-Hua Jin · 2013 · International Journal of Molecular Sciences
  99. Licochalcone B Ameliorates Liver Cancer via Targeting of Apoptotic Genes, DNA Repair Systems, and Cell Cycle Control.
    Kadry M. Sadek, Tarek Kamal Abouzed, Sherif M. Nasr, Moustafa Shoukry · 2020 · PubMed Central
  100. BAX mitochondrial integration is regulated allosterically by its α1−α2 loop
    Michael A. Dengler, Leonie Gibson, Jerry M. Adams · 2021 · Cell Death and Differentiation