Bcl-xL Retrotranslocates Bax from the Mitochondria into the Cytosol
Edlich, Frank, Banerjee, Soojay, Suzuki, Motoshi, Cleland, Megan M., Arnoult, Damien, Wang, Chunxin, Neutzner, Albert, Tjandra, Nico +1 more·2011·Cell
Cited by (634)
Items 101–200 of 634
- CHCHD2 inhibits apoptosis by interacting with Bcl-x L to regulate Bax activationYuTing Liu, Hilary V. Clegg, Patrick L. Leslie, Jiehui Di, Laura A. Tollini, Yizhou Joseph He, T-H Kim, A Jin, Lee M. Graves, Junnian Zheng et al. · 2014 · Cell Death and Differentiation
- Small-molecule allosteric inhibitors of BAXThomas P. Garner, Dulguun Amgalan, Denis E. Reyna, Sheng Li, Richard N. Kitsis, Evripidis Gavathiotis · 2019 · Nature Chemical Biology
- Molecular and topological reorganizations in mitochondrial architecture interplay during Bax-mediated steps of apoptosisNicholas R. Ader, Patrick C. Hoffmann, Iva Ganeva, Alicia C. Borgeaud, Chunxin Wang, Richard J. Youle, Wanda Kukulski · 2019 · eLife
- Mitochondrial regulation of cell death: a phylogenetically conserved controlLorenzo Galluzzi, Oliver Kepp, Guido Kroemer · 2016 · Microbial Cell
- Mechanistic clues to the protective effect of chrysin against doxorubicin-induced cardiomyopathy: Plausible roles of p53, MAPK and AKT pathwaysEman M. Mantawy, Ahmed Esmat, Wesam M. El‐Bakly, Rania A. Salah El Din, Ebtehal El‐Demerdash · 2017 · Scientific Reports
- Inhibition of Bax protects neuronal cells from oligomeric Aβ neurotoxicityWataru Kudo, Lee Hp, Mark A. Smith, Xiongwei Zhu, S Matsuyama, H-g Lee · 2012 · Cell Death and Disease
- Where Killers Meet--Permeabilization of the Outer Mitochondrial Membrane during ApoptosisTom Bender, Jean‐Claude Martinou · 2013 · Cold Spring Harbor Perspectives in Biology
- Apoptosis, necroptosis, and pyroptosis as alternative cell death pathways induced by chemotherapeutic agents?Adrianna Gielecińska, Mateusz Kciuk, Esam Bashir Yahya, Tarik Ainane, Somdutt Mujwar, Renata Kontek · 2023 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- Natural Borneol, a Monoterpenoid Compound, Potentiates Selenocystine-Induced Apoptosis in Human Hepatocellular Carcinoma Cells by Enhancement of Cellular Uptake and Activation of ROS-Mediated DNA DamageJianyu Su, Haoqiang Lai, Jianping Chen, Lin Li, Yum‐Shing Wong, Tianfeng Chen, Xiaoling Li · 2013 · PLoS ONE
- Targeting BAX to drug death directlyLoren D. Walensky · 2019 · Nature Chemical Biology
- Bax transmembrane domain interacts with prosurvival Bcl-2 proteins in biological membranesVicente Andreu-Férnández, Mónica Sancho, Ainhoa Genovés, Estefanía Lucendo, Franziska Todt, Joachim Lauterwasser, Kathrin Funk, Günther Jahreis, Enríque Pérez‐Payá, Ismael Mingarro et al. · 2016 · Proceedings of the National Academy of Sciences
- Mitochondria and apoptosis: emerging conceptsXiang Li, Grant Dewson · 2015 · F1000Prime Reports
- The porin VDAC2 is the mitochondrial platform for Bax retrotranslocationJoachim Lauterwasser, Franziska Todt, Ralf M. Zerbes, Thanh Ngoc Nguyen, William James Craigen, Michael Lazarou, Martin van der Laan, Frank Edlich · 2016 · Scientific Reports
- Mechanistic perspective of mitochondrial fusion: Tubulation vs. fragmentationMafalda Escobar‐Henriques, Fabian den Brave · 2012 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- BH3‐in‐groove dimerization initiates and helix 9 dimerization expands Bax pore assembly in membranesZhang, Zhi, Subramaniam, Sabareesh, Kale, Justin, Liao, Chenyi, Huang, Bo, Brahmbhatt, Hetal, Condon, Samson GF, Lapolla, Suzanne M, Hays, Franklin A, Ding, Jingzhen et al. · 2016 · The EMBO Journal
- IF1 limits the apoptotic-signalling cascade by preventing mitochondrial remodellingDanilo Faccenda, C H Tan, Andreas Seraphim, Michael R. Duchen, Michelangelo Campanella · 2013 · Cell Death and Differentiation
- Exploiting MCL1 Dependency with Combination MEK + MCL1 Inhibitors Leads to Induction of Apoptosis and Tumor Regression in
<i>KRAS</i>
-Mutant Non–Small Cell Lung CancerNangia, Varuna, Siddiqui, Faria M., Caenepeel, Sean, Timonina, Daria, Bilton, Samantha J., Phan, Nicole, Gomez-Caraballo, Maria, Archibald, Hannah L., Li, Chendi, Fraser, Cameron et al. · 2018 · Cancer Discovery
- Bax Activation Initiates the Assembly of a Multimeric Catalyst that Facilitates Bax Pore Formation in Mitochondrial Outer MembranesYulia Kushnareva, Alexander Y. Andreyev, Tomomi Kuwana, Donald D. Newmeyer · 2012 · PLoS Biology
- Synergistic Anticancer Activity of Combined Use of Caffeic Acid with Paclitaxel Enhances Apoptosis of Non-Small-Cell Lung Cancer H1299 Cells in Vivo and in VitroJie Min, Hua Min Shen, Xi Wang, Qing Wang, Liang Yin, Yufeng Zhang, Yue Yu, Qian Yang, Zhinong Wang · 2018 · Cellular Physiology and Biochemistry
- BH3-dependent and independent activation of BAX and BAK in mitochondrial apoptosisPaul Jeng, Akane Inoue‐Yamauchi, James J.-D. Hsieh, Emily H. Y. Cheng · 2018 · Current Opinion in Physiology
- Mechanisms of mitochondrial cell deathShashank Dadsena, Cristiana Zollo, Ana J. García-Sáez · 2021 · Biochemical Society Transactions
- BAX channel activity mediates lysosomal disruption linked to Parkinson diseaseBové, Jordi, Martínez-Vicente, Marta, Dehay, Benjamin, Perier, Celine, Recasens, Ariadna, Bombrun, Agnes, Antonsson, Bruno, Vila, Miquel · 2014 · Autophagy
- Kill one or kill the many: interplay between mitophagy and apoptosisSimone Wanderoy, J. Tabitha Hees, Ramona Klesse, Frank Edlich, Angelika Bettina Harbauer · 2020 · Biological Chemistry
- Ancient and conserved functional interplay between Bcl-2 family proteins in the mitochondrial pathway of apoptosisNikolay Popgeorgiev, Jaison D Sa, Lea Jabbour, Suresh Banjara, Trang Thi Minh Nguyen, Aida Akhavan-E-Sabet, Rudy Gadet, Nikola Ralchev, Stéphen Manon, Mark G. Hinds et al. · 2020 · Science Advances
- SIRT3 Deacetylates Ceramide SynthasesSergei A. Novgorodov, Christopher L. Riley, Jarryd A. Keffler, Jin Yu, Mark S. Kindy, Wendy B. Macklin, David B. Lombard, Tatyana I. Gudz · 2015 · Journal of Biological Chemistry
- Targeting anti‐apoptotic BCL 2 family proteins in haematological malignancies – from pathogenesis to treatmentMeike Vogler, Harriet S. Walter, Martin J.S. Dyer · 2017 · British Journal of Haematology
- Epigenetic Deregulation of Apoptosis in CancersEzgi Ozyerli‐Goknar, Tugba Bagci Onder · 2021 · Cancers
- Artesunate induces apoptosis via a Bak‐mediated caspase‐independent intrinsic pathway in human lung adenocarcinoma cellsChen-juan Zhou, Wenliang Pan, Xiaoping Wang, Tong Sheng Chen · 2012 · Journal of Cellular Physiology
- Bimetallic Organic Frameworks of High Piezovoltage for Sono‐Piezo Dynamic TherapyQiqi Wang, Yue Tian, Meng Yao, Jingke Fu, Lianzhou Wang, Yingchun Zhu · 2023 · Advanced Materials
- The Cell and Molecular Biology of Glaucoma: Mechanisms of Retinal Ganglion Cell DeathRobert W. Nickells · 2012 · Investigative Ophthalmology & Visual Science
- T-cell death following immune activation is mediated by mitochondria-localized SARMPorkodi Panneerselvam, Laishram Pradeepkumar Singh, Viknesvaran Selvarajan, Wee Joo Chng, Siok‐Bian Ng, Nguan Soon Tan, Bow Ho, Jianzhu Chen, Jeak Ling Ding · 2012 · Cell Death and Differentiation
- Bcl-xL mediates RIPK3-dependent necrosis in M. tuberculosis-infected macrophagesXuanyin Zhao, Nargis Khan, Hua Tian Gan, Fanny Tzelepis, Tomoyasu Nishimura, S-Y Park, Maziar Divangahi, Heinz G. Remold · 2017 · Mucosal Immunology
- Platelets induce apoptosis via membrane-bound FasLRebecca Schleicher, Frank Reichenbach, Peter Kraft, Anil Kumar, Mario Lescan, Franziska Todt, Kerstin Göbel, Ingo Hilgendorf, Tobias Geisler, Axel Bauer et al. · 2015 · Blood
- Death upon a Kiss: Mitochondrial Outer Membrane Composition and Organelle Communication Govern Sensitivity to BAK/BAX-Dependent ApoptosisThibaud T. Renault, Jerry E. Chipuk · 2013 · Chemistry & Biology
- IIIDB: a database for isoform-isoform interactions and isoform network modulesYu‐Ting Tseng, Wenyuan Li, Ching‐Hsien Chen, Shihua Zhang, Jeremy J.W. Chen, Xianghong Jasmine Zhou, Chun-Chi Liu · 2015 · BMC Genomics
- Three-dimensional structure of Bax-mediated pores in membrane bilayersX-P Xu, Dayong Zhai, Eugene Kim, M Swift, John C. Reed, Niels Volkmann, Dorit Hanein · 2013 · Cell Death and Disease
- The third model of Bax/Bak activation: a Bcl-2 family feud finally resolved?Xu Luo, Katelyn L. O’Neill, Kai Huang · 2020 · F1000Research
- Lipid unsaturation promotes BAX and BAK pore activity during apoptosisShashank Dadsena, Rodrigo Cuevas Arenas, Gonçalo Vieira, Susanne Brodesser, Manuel N. Melo, Ana J. García‐Sáez · 2024 · Nature Communications
- After Embedding in Membranes Antiapoptotic Bcl-XL Protein Binds Both Bcl-2 Homology Region 3 and Helix 1 of Proapoptotic Bax Protein to Inhibit Apoptotic Mitochondrial PermeabilizationJingzhen Ding, Blaine H. M. Mooers, Zhi Zhang, Justin Kale, Domina Falcone, Jamie Mcnichol, Bo Huang, Xuejun C. Zhang, Chengguo Xing, David William Andrews et al. · 2014 · Journal of Biological Chemistry
- The regulation of the mitochondrial apoptotic pathway by glucocorticoid receptor in collaboration with Bcl-2 family proteins in developing T cellsLilla Prenek, Ferenc Boldizsár, Réka Kugyelka, Emese Ugor, Gergely Berta, Pèter Németh, Tímea Berki · 2016 · APOPTOSIS
- The chemo-prophylactic efficacy of an ethanol Moringa oleifera leaf extract against hepatocellular carcinoma in ratsKadry M. Sadek, Tarek Kamal Abouzed, Reham Abouelkhair, Sherif M. Nasr · 2017 · Pharmaceutical Biology
- Interrogating the relevance of mitochondrial apoptosis for vertebrate development and postnatal tissue homeostasisSelma Tuzlak, Thomas Kaufmann, Andreas Villunger · 2016 · Genes & Development
- Quantitative interactome of a membrane Bcl-2 network identifies a hierarchy of complexes for apoptosis regulationBleicken, Stephanie, Hantusch, Annika, Das, Kushal Kumar, Frickey, Tancred, Garcia-Saez, Ana J. · 2017 · Nature Communications
- Shedding Light on Apoptosis at Subcellular MembranesJustin Kale, Qian Liu, Brian F. Leber, David William Andrews · 2012 · Cell
- Eltrombopag directly inhibits BAX and prevents cell deathAdam Z. Spitz, Emmanouil Zacharioudakis, Denis E. Reyna, Thomas P. Garner, Evripidis Gavathiotis · 2021 · Nature Communications
- VDAC2 and the BCL-2 family of proteinsZheng Yuan, Grant Dewson, Peter E. Czabotar, Richard W. Birkinshaw · 2021 · Biochemical Society Transactions
- Crystal structure of Bax bound to the BH3 peptide of Bim identifies important contacts for interactionAdeline Y. Robin, Kaavya Krishna Kumar, Dana Westphal, Ahmad Z. Wardak, Geoff V. Thompson, Grant Dewson, Peter M. Colman, Peter E. Czabotar · 2015 · Cell Death and Disease
- Role of Bcl-2 in tumour cell survival and implications for pharmacotherapyMary Tomek, T. Akiyama, Crispin R. Dass · 2012 · Journal of Pharmacy and Pharmacology
- Conformational Rearrangements in the Pro-apoptotic Protein, Bax, as It Inserts into MitochondriaRobert F. Gahl, Yi He, Shiqin Judy Yu, Nico Tjandra · 2014 · Journal of Biological Chemistry
- Vaccinia virus evasion of regulated cell deathDavid L. Veyer, Guia Carrara, Carlos Maluquer de Motes, Geoffrey L. Smith · 2017 · Immunology Letters
- Regulating cell death at, on, and in membranesXiaoke Chi, Justin Kale, Brian F. Leber, David William Andrews · 2014 · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research
- Bax/Bak activation in the absence of Bid, Bim, Puma, and p53J Zhang, Kai Huang, Katelyn L. O’Neill, X Pang, Xu Luo · 2016 · Cell Death and Disease
- A New View of the Lethal Apoptotic PoreGorka Basáñez, Lucian Soane, J. Marie Hardwick · 2012 · PLoS Biology
- How do viruses control mitochondria-mediated apoptosis?Simon Neumann, Souhayla El Maadidi, Laura Eva Faletti, Florian Haun, Shirin Labib, Andrea Schejtman, Ulrich Maurer, Christoph Borner · 2015 · Virus Research
- Phosphorylation of p38 MAPK mediates hypoxic preconditioning-induced neuroprotection against cerebral ischemic injury via mitochondria translocation of Bcl-xL in miceLi Zhao, Xu Liu, Jing Liang, Song Han, Yue Wang, Yanling Yin, Yanlin Luo, Junfa Li · 2013 · Brain Research
- BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-XLGeorgia Greaves, Mateus Milani, Michael Butterworth, Rachel J. Carter, Dominic P. Byrne, Patrick A. Eyers, Xu Luo, Gerald M. Cohen, Shankar Varadarajan · 2018 · Cell Death and Differentiation
- Programming cancer cells for high expression levels of Mcl1Franziska Ertel, Mai Nguyen, Anne Roulston, Gordon C. Shore · 2013 · EMBO Reports
- Asiatic Acid Alleviates Myocardial Ischemia‐Reperfusion Injury by Inhibiting the ROS‐Mediated Mitochondria‐Dependent Apoptosis PathwayChenlong Yi, Meijuan Song, Lifu Sun, Linjie Si, Dongmin Yu, Ben Li, Peng Lü, Wei Wang, Xiaowei Wang · 2022 · Oxidative Medicine and Cellular Longevity
- Bcl-2 proteins bid and bax form a network to permeabilize the mitochondria at the onset of apoptosisRobert F. Gahl, Pallavi Dwivedi, Nico Tjandra · 2016 · Cell Death and Disease
- Bcl-2 family in inter-organelle modulation of calcium signaling; roles in bioenergetics and cell survivalLewis, Abasha, Hayashi, Teruo, Su, Tsung-Ping, Betenbaugh, Michael J. · 2014 · Journal of Bioenergetics and Biomembranes
- The function of alternative splicing in the proteome: rewiring protein interactomes to put old functions into new contextsPeter Kjer-Hansen, Robert J. Weatheritt · 2023 · Nature Structural & Molecular Biology
- Structural mechanism of Bax inhibition by cytomegalovirus protein vMIAJunhe Ma, Frank Edlich, Guillermo A. Bermejo, Kristi L. Norris, Richard J. Youle, Nico Tjandra · 2012 · Proceedings of the National Academy of Sciences
- Conformation of BCL-XL upon Membrane IntegrationYong Yao, Lynn Miya Fujimoto, Nathan A. Hirshman, Andrey A. Bobkov, Antonella Antignani, Richard J. Youle, Francesca M. Marassi · 2015 · Journal of Molecular Biology
- S-palmitoylation represents a novel mechanism regulating the mitochondrial targeting of BAX and initiation of apoptosisMichael Fröhlich, Borislav Dejanovic, Hamid Kashkar, Günter Schwarz, Stephan Nußberger · 2014 · Cell Death and Disease
- Bak apoptotic pores involve a flexible C-terminal region and juxtaposition of the C-terminal transmembrane domainsSweta Iyer, F Bell, Dana Westphal, Khatira Anwari, Jacqueline M. Gulbis, Brian James Smith, Grant Dewson, Ruth M. Kluck · 2015 · Cell Death and Differentiation
- Thymol Isolated from Thymus vulgaris L. Inhibits Colorectal Cancer Cell Growth and Metastasis by Suppressing the Wnt/β-Catenin PathwayQiongyao Zeng, Yuncheng Che, Yu Zhang, Mei Chen, Qiang Guo, Wenjing Zhang · 2020 · Drug Design Development and Therapy
- Bcl-2 Family Members and the Mitochondrial Import Machineries: The Roads to DeathLisenn Lalier-Bretaudeau, François M. Vallette, Stéphen Manon · 2022 · Biomolecules
- Expanding roles of BCL-2 proteins in apoptosis execution and beyondLouise King, Lisa Hohorst, Ana J. García‐Sáez · 2023 · Journal of Cell Science
- BCL-XL expression is essential for human erythropoiesis and engraftment of hematopoietic stem cellsAfreen, Sehar, Bohler, Sheila, Müller, Alexandra, Demmerath, Eva-Maria, Weiss, Julia Miriam, Jutzi, Jonas Samuel, Schachtrup, Kristina, Kunze, Mirjam, Erlacher, Miriam · 2020 · Cell Death & Disease
- Upregulation of miR-18a-5p contributes to epidermal necrolysis in severe drug eruptionsAsako Ichihara, Zhongzhi Wang, Masatoshi Jinnin, Yuki Izuno, Naoki Shimozono, Keitaro Yamane, Akihiko Fujisawa, Chikako Moriya, Satoshi Fukushima, Yuji Inoue et al. · 2013 · Journal of Allergy and Clinical Immunology
- TOM20-mediated transfer of Bcl2 from ER to MAM and mitochondria upon induction of apoptosisLisenn Lalier-Bretaudeau, Vincent Mignard, Marie‐Pierre Joalland, Didier Lanoé, Pierre‐François Cartron, Stéphen Manon, François M. Vallette · 2021 · Cell Death and Disease
- Critical role of anti-apoptotic Bcl-2 protein phosphorylation in mitotic deathJoshua M. Eichhorn, Nandini Sakurikar, Sarah E. Alford, Rong Chu, Timothy C. Chambers · 2013 · Cell Death and Disease
- Bcl-xL controls a switch between cell death modes during mitotic arrestNourdine Kabirou Bah, Laurent Maillet, Jeremy A. Ryan, S Dubreil, Fabien Gautier, Anthony G. Letai, Philippe Paul Juin, Sophie Barillé‐Nion · 2014 · Cell Death and Disease
- Prevention of apoptosis averts glomerular tubular disconnection and podocyte loss in proteinuric kidney diseaseIevgeniia A. Burlaka, Linnéa M. Nilsson, Lena Scott, Ulla Holtbäck, Ann‐Christine Eklöf, Agnes B. Fogo, Hjalmar Brismar, Anita C. Aperia · 2016 · Kidney International
- Tight Sequestration of BH3 Proteins by BCL-xL at Subcellular Membranes Contributes to Apoptotic ResistanceJessie Pécot, Laurent Maillet, Janic Le Pen, Céline Vuillier, Sophie de Carné Trécesson, Aurélie Fétiveau, Kristopher A. Sarosiek, Florian J. Bock, Frédérique Braun, Anthony G. Letai et al. · 2016 · Cell Reports
- Mitochondrial residence of the apoptosis inducer BAX is more important than BAX oligomerization in promoting membrane permeabilizationTomomi Kuwana, Louise E. King, Katia Cosentino, Julian Suess, Ana J. García‐Sáez, Andrew P. Gilmore, Donald D. Newmeyer · 2020 · Journal of Biological Chemistry
- The Role of Mitochondria in PyroptosisQian Li, Nengxian Shi, Chen Cai, Mingming Zhang, Jing He, Ying Tan, Weijun Fu · 2021 · Frontiers in Cell and Developmental Biology
- Overcoming Cancer Resistance: Strategies and Modalities for Effective TreatmentMahesh Koirala, Mario DiPaola · 2024 · Biomedicines
- Paraquat Induces Cell Death Through Impairing Mitochondrial Membrane PermeabilityChuen‐Lin Huang, Chih-Chang Chao, Yi‐Chao Lee, Mei‐Kuang Lu, Jing‐Jy Cheng, Ying-Chen Yang, Vin-Chi Wang, Wen‐Chang Chang, Nai‐Kuei Huang · 2015 · Molecular Neurobiology
- Apoptotic foci at mitochondria: in and around Bax poresBegoña Ugarte‐Uribe, Ana J. García‐Sáez · 2017 · Philosophical Transactions of the Royal Society B Biological Sciences
- BK Polyomavirus Evades Innate Immune Sensing by Disrupting the Mitochondrial Network and Promotes MitophagyJulia Manzetti, Fabian H. Weissbach, Fabrice E. Graf, Gunhild Unterstab, Marion Wernli, Helmut Hopfer, Cinthia Beskow Drachenberg, Christine Hanssen Rinaldo, Hans Hellmuth Hirsch · 2020 · iScience
- SIRT1 activation by SRT1720 attenuates bone cancer pain via preventing Drp1-mediated mitochondrial fissionMingyue Li, Jieqiong Ding, Qiong Tang, Miaomiao Hao, Banghua Wang, Ji Wu, Liangzhu Yu, Ming Jiao, Binhua Luo, Min Xie et al. · 2018 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
- BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial AssociationMichael A. Dengler, Adeline Y. Robin, Leonie Gibson, Xiang Li, Jarrod John Sandow, Sweta Iyer, Andrew Ian Webb, Dana Westphal, Grant Dewson, Jerry M. Adams · 2019 · Cell Reports
- Regulating the BCL2 Family to Improve Sensitivity to Microtubule Targeting AgentsRobert H. Whitaker, William J. Placzek · 2019 · Cells
- Seneca Valley Virus 2C and 3Cpro Induce Apoptosis via Mitochondrion-Mediated Intrinsic PathwayTingting Liu, Xiangmin Li, Mengge Wu, Liuxing Qin, Huanchun Chen, Ping Qian · 2019 · Frontiers in Microbiology
- Regulation of Bax/mitochondria interaction by AKTLilit Simonyan, Thibaud T. Renault, Maria João Novais, Maria João Sousa, Manuela Côrte‐Real, Nadine M. Camougrand, Cécile Dahout-Gonzalez, Stéphen Manon · 2015 · FEBS Letters
- Resveratrol protects PC12 cells against OGD/R-induced apoptosis via the mitochondrial-mediated signaling pathwayXuan Liu, Xiangyang Zhu, Miao Chen, Qinmin Ge, Yong Shen, Shuming Pan · 2016 · Acta Biochimica et Biophysica Sinica
- Triclosan-induced liver injury in zebrafish (Danio rerio) via regulating MAPK/p53 signaling pathwayMi Liu, Weiming Ai, Limei Sun, Fang Fang, Xuedong Wang, Shaobo Chen, Huili Wang · 2019 · Comparative Biochemistry and Physiology Part C Toxicology & Pharmacology
- Granzyme B–Activated p53 Interacts with Bcl-2 To Promote Cytotoxic Lymphocyte–Mediated ApoptosisThouraya Ben Safta, Linda Ziani, Loëtitia Favre, Lucille Lamendour, Gwendoline Gros, Fathia Mami‐Chouaib, Denis Martinvalet, Salem Chouaı̈b, Jérôme Thiery · 2014 · The Journal of Immunology
- Traveling Bax and Forth from Mitochondria to Control ApoptosisMaría Eugenia Soriano, Luca Scorrano · 2011 · Cell
- Mitochondrial outer membrane permeabilization at the single molecule levelShashank Dadsena, Andreas Jenner, Ana J. García‐Sáez · 2021 · Cellular and Molecular Life Sciences
- Review of cancer cell resistance mechanisms to apoptosis and actual targeted therapiesMerve Kulbay, Adeline Paimboeuf, Derman Ozdemir, Jacques Bernier · 2021 · Journal of Cellular Biochemistry
- Membrane damage and repair: a thin line between life and deathCaroline Barisch, Joost C. M. Holthuis, Katia Cosentino · 2023 · Biological Chemistry
- Translocation of a Bak C-Terminus Mutant from Cytosol to Mitochondria to Mediate Cytochrome c Release: Implications for Bak and Bax Apoptotic FunctionPedro Eitz Ferrer, Paul Frederick, Jacqueline M. Gulbis, Grant Dewson, Ruth M. Kluck · 2012 · PLoS ONE
- Wip1 promotes RUNX2-dependent apoptosis in p53-negative tumors and protects normal tissues during treatment with anticancer agentsAnastasia R. Goloudina, Kan Tanoue, Arlette Hammann, Eric Fourmaux, Xavier Le Guezennec, Dmitry V. Bulavin, Sharlyn J. Mazur, Ettore Appella, Carmen Garrido, Oleg N. Demidov · 2011 · Proceedings of the National Academy of Sciences
- BCLXL gene therapy moderates neuropathology in the DBA/2J mouse model of inherited glaucomaRyan Donahue, Rachel L. Fehrman, Jenna R. Gustafson, Robert W. Nickells · 2021 · Cell Death and Disease
- Hexokinases inhibit death receptor–dependent apoptosis on the mitochondriaJoachim Lauterwasser, Franziska Todt, Aline Oelgeklaus, Annabell Schreiner, Kathrin Funk, Hugo Falquez-Medina, Ramona Klesse, Günther Jahreis, Ralf M. Zerbes, Katelyn L. O’Neill et al. · 2021 · Proceedings of the National Academy of Sciences
- Chemical modulation of cytosolic BAX homodimer potentiates BAX activation and apoptosisNadege Gitego, Bogos Agianian, Oi Wei Mak, Vasantha Kumar MV, Emily H. Y. Cheng, Evripidis Gavathiotis · 2023 · Nature Communications
- Completion of BAX recruitment correlates with mitochondrial fission during apoptosisMargaret E. Maes, Joshua A. Grosser, Rachel L. Fehrman, Cassandra L. Schlamp, Robert W. Nickells · 2019 · Scientific Reports
- Aberrant Bcl-x splicing in cancer: from molecular mechanism to therapeutic modulationZhihui Dou, Dapeng Zhao, Xiaohua Chen, Caipeng Xu, Xiaodong Jin, Xuetian Zhang, Yupei Wang, Xiaodong Xie, Qiang Li, Cuixia Di et al. · 2021 · Journal of Experimental & Clinical Cancer Research