A CXCL1 Paracrine Network Links Cancer Chemoresistance and Metastasis

Acharyya, Swarnali, Oskarsson, Thordur, Vanharanta, Sakari, Malladi, Srinivas, Kim, Juliet, Morris, Patrick G., Manova-Todorova, Katia, Leversha, Margaret +5 more·2012·Cell

DOI 10.1016/j.cell.2012.04.042

Cited by (1,000)

Items 301–400 of 1,000

Macrophages and fibroblasts as regulators of the immune response in pancreatic cancer
Mojdeh Shakiba, David Arthur Tuveson · 2025 · Nature Immunology
The epigenetic/noncoding origin of tumor dormancy
Francesco Crea, Nur Ridzwan Nur Saidy, Colin C. Collins, Yuzhuo Z. Wang · 2015 · Trends in Molecular Medicine
Tumor promoters: from chemicals to inflammatory proteins
Hirota Fujiki, Eisaburo Sueoka, Masami Suganuma · 2013 · Journal of Cancer Research and Clinical Oncology
Three-dimensional bio-printing: A new frontier in oncology research
Nitin B. Charbe, Paul A. McCarron, Murtaza M. Tambuwala · 2017 · World Journal of Clinical Oncology
Drug screening in Drosophila; why, when, and when not?
Tin Tin Su · 2019 · Wiley Interdisciplinary Reviews Developmental Biology
Determinants of renal cell carcinoma invasion and metastatic competence
Kangsan Kim, Qin-Bo Zhou, A. Christie, C. Stevens, Yuanqing Ma, Oreoluwa Onabolu, Suneetha Chintalapati, Tiffani McKenzie, V. Tcheuyap, Layton Woolford et al. · 2021 · Nature Communications
Tumor-Associated Mast Cells in Thyroid Cancer
Carla Visciano, Nella Prevete, Federica Liotti, Gianni Marone · 2015 · International Journal of Endocrinology
Targeting chemotherapy-induced PTX3 in tumor stroma to prevent the progression of drug-resistant cancers
Jhih-Ying Chi, Yu‐Wei Hsiao, Chien‐Feng Li, Yu-Chih Lo, Zu‐Yau Lin, Jhen‐Yi Hong, Yang-Ming Liu, Xiu Han, Shao‐Ming Wang, Ben‐Kuen Chen et al. · 2015 · Oncotarget
Immunological consequences of chemotherapy: Single drugs, combination therapies and nanoparticle-based treatments
Anusha Pusuluri, Debra Wu, Samir Mitragotri · 2019 · Journal of Controlled Release
Effects of microenvironment in osteosarcoma on chemoresistance and the promise of immunotherapy as an osteosarcoma therapeutic modality
Lei Yu, Jian Zhang, Yunfeng Li · 2022 · Frontiers in Immunology
Development and characterization of a reliable mouse model of colorectal cancer metastasis to the liver
Yu Zhang, Celestia Davis, James C. Ryan, Cory Janney, Maria Marjorette O. Peña · 2013 · Clinical & Experimental Metastasis
Omentum and bone marrow: how adipocyte-rich organs create tumour microenvironments conducive for metastatic progression
H. C. Gusky, Jonathan D Diedrich, O. MacDougald, Izabela Podgorski · 2016 · Obesity Reviews
Neutrophils and Granulocytic MDSC: The Janus God of Cancer Immunotherapy
Serena Zilio, Paolo Serafini · 2016 · Vaccines
Immune profiling of pre- and post-treatment breast cancer tissues from the SWOG S0800 neoadjuvant trial
Xiaotong Li, Sarah E. Warren, Vasiliki Pelekanou, Vikram B. Wali, Alessandra Cesano, Mingdong Liu, Patrick J. Danaher, Nathane Elliott, Zeina A. Nahleh, Daniel F. Hayes et al. · 2019 · Journal for ImmunoTherapy of Cancer
Elevation of CXCL1 indicates poor prognosis and radioresistance by inducing mesenchymal transition in glioblastoma
Alafate Wahafu, Xiaodong Li, Jie Zuo, Hua Zhang, Jianyang Xiang, Wei Wu, Wanfu Xie, Xiaobin Bai, Maode Wang, Jia Wang · 2020 · CNS Neuroscience & Therapeutics
Chemokines and NSCLC: Emerging role in prognosis, heterogeneity, and therapeutics
Saumya Srivastava, Atish Ranjan Mohanty, Arin Nam, Sharad S. Singhal, Ravi Salgia · 2022 · Seminars in Cancer Biology
Aurora-A contributes to cisplatin resistance and lymphatic metastasis in non-small cell lung cancer and predicts poor prognosis
Jie Xu, Cai-feng Yue, Wei-hua Zhou, Yuan Qian, Yan Zhang, Shao-wu Wang, An-wen Liu, Quentin Liu · 2014 · Journal of Translational Medicine
Metastatic growth instructed by neutrophil-derived transferrin
Wei Ping Liang, Qin Li, Napoleone Ferrara · 2018 · Proceedings of the National Academy of Sciences
CXCL2/CXCR2 axis induces cancer stem cell characteristics in CPT‐11‐resistant LoVo colon cancer cells via Gαi‐2 and Gαq/11
Ming‐Cheng Chen, Rathinasamy Baskaran, Nien‐Hung Lee, Hsi-Hsien Hsu, Tsung‐Jung Ho, Chuan‐Chou Tu, Yueh‐Min Lin, Vijaya Padma Viswanadha, Wei‐Wen Kuo, Chih‐Yang Huang · 2018 · Journal of Cellular Physiology
Epithelial-mesenchymal transition in human gastric cancer cell lines induced by TNF-α-inducing protein ofHelicobacter pylori
Tatsuro Watanabe, Atsushi Takahashi, Kaori Suzuki, Miki Kurusu, Kensei Yamaguchi, Hirota Fujiki, Masami Suganuma · 2013 · International Journal of Cancer
AKIP1 promotes angiogenesis and tumor growth by upregulating CXC-chemokines in cervical cancer cells
Wenying Zhang, Qiongwei Wu, Chao Wang, Longtao Yang, Ping Liu, Chengbin Ma · 2018 · Molecular and Cellular Biochemistry
USP12 downregulation orchestrates a protumourigenic microenvironment and enhances lung tumour resistance to PD-1 blockade
Zhaojuan Yang, Guiqin Xu, Boshi Wang, Yun Liu, Li Zhang, Tiantian Jing, Ming Tang, Xiaoli Xu, Kun Jiao, Lvzhu Xiang et al. · 2021 · Nature Communications
Wild-Type N-Ras, Overexpressed in Basal-like Breast Cancer, Promotes Tumor Formation by Inducing IL-8 Secretion via JAK2 Activation
Ze-Yi Zheng, Lin Hai Tian, Wen Bu, Cheng Fan, Xia Gao, Hai Wang, Yi‐Hua Liao, Yi Li, Michael T. Lewis, Dean P. Edwards et al. · 2015 · Cell Reports
Molecular Pathways: Tumor-Derived Microvesicles and Their Interactions with Immune CellsIn Vivo
Ferdinando Pucci, Mikaël J. Pittet · 2013 · Clinical Cancer Research
Roles of DNA repair enzyme OGG1 in innate immunity and its significance for lung cancer
Spiros Vlahopoulos, Maria Adamaki, Nikolas Khoury, Vassilis C. Zoumpourlis, Istvan R. Boldogh · 2018 · Pharmacology & Therapeutics
Current perspectives of cancer-associated fibroblast in therapeutic resistance: potential mechanism and future strategy
Dhruba Kadel, Yu Zhang, Haoran Sun, Yue Zhao, Qiongzhu Dong, Lun‐Xiu Qin · 2019 · Cell Biology and Toxicology
Macrophages-aPKCɩ-CCL5 Feedback Loop Modulates the Progression and Chemoresistance in Cholangiocarcinoma
Tao Yang, Zhengdong Deng, Lei Xu, Xiangyu Li, Yang Tan, Yawei Qian, Yun Lü, Li Tian, Wei Yao, Jianming Wang · 2022 · Journal of Experimental & Clinical Cancer Research
Pushing tumor cells towards a malignant phenotype: Stimuli from the microenvironment, intercellular communications and alternative roads
Fabrizio Marcucci, Matteo Bellone, Carmelo Antonio Caserta, Angelo Corti · 2013 · International Journal of Cancer
Overexpression of GAB2 in ovarian cancer cells promotes tumor growth and angiogenesis by upregulating chemokine expression
Carrie A. Duckworth, Linxue Zhang, Steven Lewis Carroll, Stephen P. Ethier, Hiu Wing Cheung · 2015 · Oncogene
XIAOPI formula inhibits the pre-metastatic niche formation in breast cancer via suppressing TAMs/CXCL1 signaling
Yifeng Zheng, Neng Wang, Shengqi Wang, Bowen Yang, Honglin Situ, Linda L. D. Zhong, Yi Heng Lin, Zhiyu Wang · 2020 · Cell Communication and Signaling
Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response
Ruhul Amin, Anjali Shukla, Jacqueline Jufen Zhu, Sohyoung Kim, Ping Wang, Simon Zhongyuan Tian, Andy D. Tran, Debasish Paul, Steven D. Cappell, Sandra Sczerba Burkett et al. · 2021 · Nature Communications
Chemoproteomic mapping of the glycolytic targetome in cancer cells
Yang Tian, Ning Wan, Hanqing Zhang, Chang Shao, Ming Ding, Qiuyu Bao, Hai Hu, Huiyong Sun, Chenguang Liu, Kun Zhou et al. · 2023 · Nature Chemical Biology
CXCR2-Driven Ovarian Cancer Progression Involves Upregulation of Proinflammatory Chemokines by Potentiating NF-κB Activation via EGFR-Transactivated Akt Signaling
Yuan-Lin Dong, Syeda M. Kabir, Eun-Sook Lee, Deok‐Soo Son · 2013 · PLoS ONE
S100A9 and EGFR gene signatures predict disease progression in muscle invasive bladder cancer patients after chemotherapy
W.T. Kim, John Kim, Chunri Yan, Pildu Jeong, Song‐Yi Choi, O. J. Lee, Y.B. Chae, Seok Joong Yun, S.C. Lee, W.J. Kim · 2014 · Annals of Oncology
Roles of S100 family members in drug resistance in tumors: Status and prospects
Xin Hua, Hongming Zhang, Jinfang Jia, Shanshan Chen, Yue Sun, Xiaoli Zhu · 2020 · Biomedicine & Pharmacotherapy
Cancer-Derived VEGF-C Increases Chemokine Production in Lymphatic Endothelial Cells to Promote CXCR2-Dependent Cancer Invasion and MDSC Recruitment
Jingyi Chen, You-Syuan Lai, Pei‐Yi Chu, Shih‐Hsuan Chan, Lu‐Hai Wang, Wen‐Chun Hung · 2019 · Cancers
Single-cell transcriptome analysis reveals cellular heterogeneity in the ascending aortas of normal and high-fat diet-fed mice
Hao Kan, Ka Zhang, Aiqin Mao, Li Geng, Mengru Gao, Lei Feng, Qingjun You, Xin Ma · 2021 · Experimental & Molecular Medicine
Therapeutic potential of chemokine signal inhibition for metastatic breast cancer
Takanori Kitamura, Jeffrey W. Pollard · 2015 · Pharmacological Research
Myeloid-derived suppressor cells are essential partners for immune checkpoint inhibitors in the treatment of cisplatin-resistant bladder cancer
Yuji Takeyama, Minoru Kato, Satoshi Tamada, Yukari Azuma, Yasuomi Shimizu, Taro Iguchi, Takeshi Yamasaki, Min Gi, Hideki Wanibuchi, Tatsuya Nakatani · 2020 · Cancer Letters
Stromal oncostatin M cytokine promotes breast cancer progression by reprogramming the tumor microenvironment
Angela M. Araujo, Andrea Abaurrea, Peio Azcoaga, Joanna I. López-Velazco, Sara Manzano, Javier Rodríguez, Ricardo Rezola, Leire Egia‐Mendikute, Fátima Valdés‐Mora, Juana María Flores et al. · 2022 · Journal of Clinical Investigation
SOCS3 Deficiency in Myeloid Cells Promotes Tumor Development: Involvement of STAT3 Activation and Myeloid-Derived Suppressor Cells
Hao Yu, Yudong Liu, Braden C. McFarland, Jessy S. Deshane, Douglas R. Hurst, Selvarangan Ponnazhagan, Etty N. Benveniste, Hongwei Qin · 2015 · Cancer Immunology Research
Network-pharmacology-based validation of TAMS/CXCL-1 as key mediator of XIAOPI formula preventing breast cancer development and metastasis
Neng Wang, Yifeng Zheng, Jiangyong Gu, Youli Cai, Shengqi Wang, Fengxue Zhang, Jianping Chen, Honglin Situ, Yi Heng Lin, Zhiyu Wang · 2017 · Scientific Reports
Tumor-infiltrating neutrophils predict benefit from adjuvant chemotherapy in patients with muscle invasive bladder cancer
Lin Zhou, Le Xu, Lingli Chen, Qiang Fu, Zheng Liu, Yuan Chang, Zongming Lin, Jiejie Xu · 2017 · OncoImmunology
Cancer-Associated Fibroblasts in Breast Cancer Treatment Response and Metastasis
Patricia Fernández‐Nogueira, Gemma Fuster, Álvaro Gutiérrez-Uzquiza, Pere Gascón, Neus Carbó, Paloma Bragado · 2021 · Cancers
HPV associated tumor cells control tumor microenvironment and leukocytosis in experimental models
Simone C. Stone, R. A. M. Rossetti, Aleida Maria Lima, Ana Paula Lepique · 2014 · Immunity Inflammation and Disease
The role of interleukin-8 (CXCL8) and CXCR2 in acquired chemoresistance of human colorectal carcinoma cells HCT116
Daiva Dabkevičienė, Violeta Jonušienė, Vilmantė Žitkutė, Eglė Žalytė, Pranas Grigaitis, Vida Kirvelienė, Aušra Sasnauskienė · 2015 · Medical Oncology
Somatic mutations in leukocytes infiltrating primary breast cancers
Maria Kleppe, Elizabeth Anne Comen, Hannah Yong Wen, Lennart Bastian, Brian Blum, Franck T Rapaport, Matthew Keller, Zvika Granot, Nicolas Socci, Agnes J. Viale et al. · 2015 · npj Breast Cancer
Energy metabolism in cancer stem cells
Xuan Zhu, Huihui Chen, Chenyi Gao, Xinxin Zhang, Jingxin Jiang, Yi Zhang, Jun Fang, Feng Zhao, Zhigang Chen · 2020 · World Journal of Stem Cells
NF-κB in Gastric Cancer Development and Therapy
Supattra Chaithongyot, Phatcharida Jantaree, Olga V. Sokolova, Michael Naumann · 2021 · Biomedicines
Immunological nanomaterials to combat cancer metastasis
Yuanbo Pan, Junjie Cheng, Yang Zhu, Jianmin Zhang, Wenpei Fan, Xiaoyuan Shawn Chen · 2024 · Chemical Society Reviews
The mutant p53 mouse as a pre-clinical model
James G. Jackson, Guillermina Lozano · 2013 · Oncogene
Galectin-1 Mediates Chronic STING Activation in Tumors to Promote Metastasis through MDSC Recruitment
Dhanya K. Nambiar, Vignesh Viswanathan, Hongbin Cao, Weiruo Zhang, Li Guan, Manish Chamoli, Brittany Holmes, Christina S. Kong, Rachel Hildebrand, Amanda Jeanette Koong et al. · 2023 · Cancer Research
Neutrophils in cancer: from biology to therapy
Leo Koenderman, Nienke Vrisekoop · 2024 · Cellular and Molecular Immunology
Inflammation‐induced S100A8 activates I d3 and promotes colorectal tumorigenesis
Xuemei Zhang, Feiyan Ai, Xiayu Li, Xiaoling She, Nan Li, Anliu Tang, Zailong Qin, Qiurong Ye, Li Tian, Guiyuan Li et al. · 2015 · International Journal of Cancer
Microenvironment in metastasis: roadblocks and supportive niches
Maren Pein, Thórdur Óskarsson · 2015 · American Journal of Physiology-Cell Physiology
Downregulation of miR-101 contributes to epithelial-mesenchymal transition in cisplatin resistance of NSCLC cells by targeting ROCK2
Zhiqiang Ye, Shengli Yin, Zhongzhen Su, Mingjun Bai, Haibo Zhang, Ziqing Hei, Songwang Cai · 2016 · Oncotarget
Tumor-derived cytokines impair myogenesis and alter the skeletal muscle immune microenvironment
Kelly A. Hogan, Dong Seong Cho, Paige C. Arneson‐Wissink, Adrienne Samani, Patrick A. Palines, Yanan Yang, Jason D. Doles · 2017 · Cytokine
Overexpression of CXCL2 inhibits cell proliferation and promotes apoptosis in hepatocellular carcinoma
Jun Ding, Kangdi Xu, Jie Zhang, Bingyi Lin, Yubo Wang, Shengyong Yin, Haiyang Xie, Lin Zhou, Shusen Zheng · 2018 · BMB Reports
Inflammation-Driven Breast Tumor Cell Plasticity: Stemness/EMT, Therapy Resistance and Dormancy
Tamir Baram, Linor Rubinstein-Achiasaf, Hagar Ben-Yaakov, Adit Ben‐Baruch · 2021 · Frontiers in Oncology
Role of Cytokines and Chemokines in NSCLC Immune Navigation and Proliferation
Sowmya Ramachandran, Amit Kumar Verma, Kapil Dev, Yamini Goyal, Deepti Bhatt, Mohammed A. Alsahli, Arshad Husain Rahmani, Ahmad Almatroudi, Saleh A. Almatroodi, Faris Alrumaihi et al. · 2021 · Oxidative Medicine and Cellular Longevity
WNT5A Inhibits Metastasis and Alters Splicing of Cd44 in Breast Cancer Cells
Wen G. Jiang, David K. Crossman, Elizabeth Mitchell, Philip Sohn, Michael R. Crowley, Rosa A. Serra · 2013 · PLoS ONE
Plasminogen activator inhibitor-1 enhances radioresistance and aggressiveness of non-small cell lung cancer cells
JiHoon Kang, Wanyeon Kim, TaeWoo Kwon, HyeSook Youn, Joong‐Sun Kim, BuHyun Youn · 2016 · Oncotarget
The impact of human adipose tissue-derived stem cells on breast cancer cells: implications for cell-assisted lipotransfers in breast reconstruction
Eva Koellensperger, Lilly-Claire Bonnert, Inka Zoernig, Frederik Marmé, Stefanie Sandmann, Günter Germann, Felix Gramley, Uwe Leimer · 2017 · Stem Cell Research & Therapy
Analysis of the Prognosis and Therapeutic Value of the CXC Chemokine Family in Head and Neck Squamous Cell Carcinoma
Yongchao Li, Tinghui Wu, Shujuan Gong, Hangzheng Zhou, Lufei Yu, Meiyan Liang, Ruijun Shi, Zhen-Hui Wu, Jinpei Zhang, Shuwei Li · 2021 · Frontiers in Oncology
Organ-specific adaptive signaling pathway activation in metastatic breast cancer cells
Riesa M. Burnett, Kelly E. Craven, Purna Krishnamurthy, Chirayu Pankaj Goswami, Sunil Badve, Peter Anthony Crooks, William P. Mathews, Poornima Bhat‐Nakshatri, Harikrishna Nakshatri · 2015 · Oncotarget
Prognostic Significance of MYH9 Expression in Resected Non-Small Cell Lung Cancer
Ken Katono, Yuichi Sato, Shi‐Xu Jiang, Makoto Kobayashi, Ryo Nagashio, Shinichiro Ryuge, Eriko Fukuda, Naoki Goshima, Yukitoshi Satoh, Makoto Saegusa et al. · 2015 · PLoS ONE
Cancer-Associated Oxidoreductase ERO1-α Drives the Production of Tumor-Promoting Myeloid-Derived Suppressor Cells via Oxidative Protein Folding
Tsutomu Tanaka, Toshimitsu Kajiwara, Toshihiko Torigoe, Yoshiharu Okamoto, Noriyuki Sato, Yasuaki Tamura · 2015 · The Journal of Immunology
Cancer-Associated Fibroblasts in the Breast Tumor Microenvironment
María Belén Giorello, Francisco Raúl Borzone, Vivian Labovsky, Flavia Piccioni, Norma Alejandra Chasseing · 2021 · Journal of Mammary Gland Biology and Neoplasia
IRF7 regulates the development of granulocytic myeloid-derived suppressor cells through S100A9 transrepression in cancer
Qi Yang, Xing Li, Han Chen, Yingjiao Cao, Qiang Xiao, Yun He, Jianyang Wei, Jie Zhou · 2017 · Oncogene
Cytokine-mediated therapeutic resistance in breast cancer
Chunli Tan, Weizi Hu, Yunjie He, Yanyan Zhang, Guangqin Zhang, Yong Xu, Jinhai Tang · 2018 · Cytokine
An updated review on the role of the CXCL8-CXCR1/2 axis in the progression and metastasis of breast cancer
Amaresh Mishra, Kamrul Hassan Suman, Nisha Nair, Jaseela Majeed, Vishwas Tripathi · 2021 · Molecular Biology Reports
Cytokine profiling of docetaxel-resistant castration-resistant prostate cancer
Kate Lynette Mahon, H-M Lin, Lesley E. Castillo, B Y Lee, Michelle Lee-Ng, Mark D. Chatfield, Karen Chiam, Samuel N. Breit, David Alexander Brown, Mark P. Molloy et al. · 2015 · British Journal of Cancer
An inflammatory vicious cycle: Fibroblasts and immune cell recruitment in cancer
Yael Raz, Neta Erez · 2013 · Experimental Cell Research
CXCR2: a target for pancreatic cancer treatment?
Kathleen M. Hertzer, Graham W. Donald, Oscar Joe Hines · 2013 · Expert Opinion on Therapeutic Targets
CXCR2 Macromolecular Complex in Pancreatic Cancer: A Potential Therapeutic Target in Tumor Growth
Shuo Wang, Yanning Wu, Yuning Hou, Xiaoqing Guan, Marcello P. Castelvetere, Jacob J. Oblak, Sanjeev Banerjee, Theresa Marie Filtz, Fazlul H. Sarkar, Xuequn Chen et al. · 2013 · Translational Oncology
Cancer-Associated Muscle Wasting—Candidate Mechanisms and Molecular Pathways
Victoria Armstrong, Liam W. Fitzgerald, Oliver F. Bathe · 2020 · International Journal of Molecular Sciences
Chemokines orchestrate tumor cells and the microenvironment to achieve metastatic heterogeneity
Sugandha Saxena, Rakesh K. Singh · 2021 · Cancer and Metastasis Reviews
Cancer-associated fibroblasts: tumor defenders in radiation therapy
Yalin Zhang, Na Lv, Manshi Li, Ming Liu, Chunli Wu · 2023 · Cell Death and Disease
Metastasis-associated protein S100A4 induces a network of inflammatory cytokines that activate stromal cells to acquire pro-tumorigenic properties
Ingrid J. Bettum, Kotryna Vasiliauskaite, Vigdis Nygaard, Trevor Clancy, Solveig Pettersen, Ellen M. Tenstad, Gunhild Mari Mælandsmo, Lina Prasmickaite · 2013 · Cancer Letters
Pleiotropic effects of cancer cells’ secreted factors on human stromal (mesenchymal) stem cells
Mashael Al-Toub, Abdulaziz Almusa, Mohammed Almajed, May Salem Al-Nbaheen, Moustapha S Kassem, Abdullah M. Aldahmash, Nehad M. Alajez · 2013 · Stem Cell Research & Therapy
Lymphocyte-Monocyte Ratio Significantly Predicts Recurrence in Papillary Thyroid Cancer
Mitsuo Yokota, Hiroshi Katoh, Hiroshi Nishimiya, Mariko Kikuchi, Yoshimasa Kosaka, Norihiko Sengoku, Masahiko Watanabe, Keishi Yamashita · 2019 · Journal of Surgical Research
Chronic Pancreatitis and the Development of Pancreatic Cancer
Hemanth Kumar Kandikattu, Sathisha Upparahalli Venkateshaiah, Anil Mishra · 2020 · Endocrine Metabolic & Immune Disorders - Drug Targets
Neutrophils’ dual role in cancer: from tumor progression to immunotherapeutic potential
Gujie Wu, Binyang Pan, Haochun Shi, Yanjun Yi, Xiaobin Zheng, Huiyun Ma, Mengnan Zhao, Zhenshan Zhang, Lin Cheng, Yiwei Huang et al. · 2024 · International Immunopharmacology
Tumor microenvironment: Nurturing cancer cells for immunoevasion and druggable vulnerabilities for cancer immunotherapy
Hongyang Yu, Jinyang Li, Shiyin Peng, Qin Liu, Dongfeng Chen, Zongsheng He, Junyu Xiang, Bin Wang · 2024 · Cancer Letters
Myeloid-derived cells are key targets of tumor immunotherapy
José Medina‐Echeverz, Fernando Aranda, Pedro Berraondo · 2014 · OncoImmunology
Progression of EGFR-Mutant Lung Adenocarcinoma is Driven By Alveolar Macrophages
Don-Hong Wang, Hyun‐Sung Lee, David K. Yoon, Gerald J. Berry, Thomas M. Wheeler, David J. Sugarbaker, Farrah Kheradmand, Edgar G. Engleman, Bryan M. Burt · 2016 · Clinical Cancer Research
Neutrophils: Homing in on the myeloid mechanisms of metastasis
Joshua D.G. Leach, Jennifer P. Morton, Owen James Sansom · 2017 · Molecular Immunology
The chemokine CXCL1 and its receptor CXCR2 contribute to chronic stress‐induced depression in mice
Huihui Chai, Xiao‐Chun Fu, Liang Ma, Haitao Sun, G Chen, Min‐Ying Song, Weixuan Chen, Yong‐Sheng Chen, Min‐Xuan Tan, Yan‐Wu Guo et al. · 2019 · The FASEB Journal
Adaptation and selection shape clonal evolution of tumors during residual disease and recurrence
Andrea Walens, Jiaxing Lin, Jeffrey S. Damrauer, Brock J. McKinney, Ryan Lupo, Rachel Newcomb, Douglas B. Fox, Nathaniel W. Mabe, Jeremy S. Gresham, Zhecheng Sheng et al. · 2020 · Nature Communications
Glycogen Synthase Kinase 3β Sustains Invasion of Glioblastoma via the Focal Adhesion Kinase, Rac1, and c-Jun N-Terminal Kinase-Mediated Pathway
Yuri Chikano, Takahiro Domoto, Takuya Furuta, Hemragul Sabit, Ayako Kitano-Tamura, Ilya V. Pyko, Takahisa Takino, Yoshimichi Sai, Yutaka Hayashi, Hiroshi Sato et al. · 2014 · Molecular Cancer Therapeutics
Immunosuppressive cell death in cancer
Jiajie Hou, Tim F. Greten, Qiang Xia · 2017 · Nature reviews. Immunology
S100A8/A9 Induced by Interaction with Macrophages in Esophageal Squamous Cell Carcinoma Promotes the Migration and Invasion of Cancer Cells via Akt and p38 MAPK Pathways
Kohei Tanigawa, Shuichi Tsukamoto, Yu‐ichiro Koma, Yu Kitamura, Satoshi Urakami, Masaki Shimizu, Masataka Fujikawa, Takayuki Kodama, Mari Nishio, Manabu Shigeoka et al. · 2021 · American Journal Of Pathology
The loss of epithelial Smad4 drives immune evasion via CXCL1 while displaying vulnerability to combinatorial immunotherapy in gastric cancer.
Hyeok-Won An, Sang Hyeok Seok, Jong-Wan Kwon, A. Choudhury, Jeong-Seop Oh, D. Voon, Dae-Yong Kim, Jun Won Park · 2022 · Cell Reports
Involvement in Tumorigenesis and Clinical Significance of CXCL1 in Reproductive Cancers: Breast Cancer, Cervical Cancer, Endometrial Cancer, Ovarian Cancer and Prostate Cancer
Jan Korbecki, Mateusz Bosiacki, Katarzyna Barczak, Ryta Łagocka, Agnieszka Brodowska, Dariusz Chlubek, Irena Baranowska‐Bosiacka · 2023 · International Journal of Molecular Sciences
Tamoxifen Directly Inhibits Platelet Angiogenic Potential and Platelet-Mediated Metastasis
Kelly Elizabeth Johnson, Jodi A. Forward, Mason D. Tippy, Julia R. Ceglowski, Saleh H. El-Husayni, Rajesh Kulenthirarajan, Kellie R. Machlus, Erica L. Mayer, Joseph E. Italiano, Elisabeth M. Battinelli · 2017 · Arteriosclerosis Thrombosis and Vascular Biology
The distinct role of strand-specific miR-514b-3p and miR-514b-5p in colorectal cancer metastasis
Linlin Ren, Tingting Yan, Chaoqin Shen, Jia‐Yin Tang, Xuan Kong, Yingchao Wang, Jinxian Chen, Qiang Liu, Jie He, Ming Zhong et al. · 2018 · Cell Death and Disease
Conditioning solid tumor microenvironment through inflammatory chemokines and S100 family proteins
Mohd Wasim Nasser, Mohamad Elbaz, Dinesh Kumar Ahirwar, Ramesh Kumar Ganju · 2015 · Cancer Letters
Optimal cutoff of pretreatment neutrophil-to-lymphocyte ratio in head and neck cancer patients: a meta-analysis and validation study
Jae‐Keun Cho, Myoung Woo Kim, Ick Soo Choi, Uk Yeol Moon, Min‐Ji Kim, Insuk Sohn, Seonwoo Kim, Han‐Sin Jeong · 2018 · BMC Cancer
Andrographolide potentiates PD-1 blockade immunotherapy by inhibiting COX2-mediated PGE2 release
Wen Liu, Ting Fan, Manru Li, Guohui Zhang, Wenjie Guo, Xiaoling Yang, Chunhong Jiang, Xiang Li, Xiangyu Xu, Tang Anshu et al. · 2020 · International Immunopharmacology
The MNK1/2–eIF4E Axis Supports Immune Suppression and Metastasis in Postpartum Breast Cancer
Qianyu Guo, Margarita Bartish, Christophe Gonçalves, Fan Huang, Julian Smith-Voudouris, Sai Sakktee Krisna, Samuel E.J. Preston, Audrey Émond, Vivian Z. Li, Claudia U. Duerr et al. · 2021 · Cancer Research