Heme-mediated SPI-C induction promotes monocyte differentiation into iron-recycling macrophages

Haldar, Malay, Kohyama, Masako, So, Alex Yick-Lun, KC, Wumesh, Wu, Xiaodi, Briseño, Carlos G., Satpathy, Ansuman T., Kretzer, Nicole M. +8 more·2014·Cell

DOI 10.1016/j.cell.2014.01.069

Cited by (431)

Items 101–200 of 431

A pairwise cytokine code explains the organism-wide response to sepsis
Michihiro Takahama, Ashwini Patil, Katherine Johnson, Denis Cipurko, Yoshimi Miki, Yoshitaka Taketomi, Peter S. Carbonetto, Madison Plaster, Gabriella Richey, Surya Pandey et al. · 2024 · Nature Immunology
Chronic TLR7 and TLR9 signaling drives anemia via differentiation of specialized hemophagocytes
Holly M. Akilesh, Matthew B. Buechler, Jeffrey M. Duggan, William O. Hahn, Bharati Matta, Xizhang Sun, Griffin M. Gessay, Elizabeth Whalen, Mike J. Mason, Scott Presnell et al. · 2019 · Science
Origins and diversity of macrophages in health and disease
Gopalkrishna Sreejit, Andrew J. Fleetwood, Andrew James Murphy, Prabhakara R. Nagareddy · 2020 · Clinical & Translational Immunology
Human Blood CD1c+ Dendritic Cells Promote Th1 and Th17 Effector Function in Memory CD4+ T Cells
Ingrid Leal Rojas, Wai Hong Mok, Frances Elizabeth Pearson, Yoshihito Minoda, Tony Kenna, Ross Thomas Barnard, Kristen J. Radford · 2017 · Frontiers in Immunology
Macrophage iron homeostasis and polarization in the context of cancer
Michaela Jung, Christina Mertens, Bernhard Brüne · 2014 · Immunobiology
Resident tissue macrophages: Key coordinators of tissue homeostasis beyond immunity
Jia Zhao, Ilya Andreev, Hernandez Moura Silva · 2024 · Science Immunology
Ironing Out the Details: How Iron Orchestrates Macrophage Polarization
Yaoyao Xia, Yikun Li, Xiaoyan Wu, Qingzhuo Zhang, Siyuan Chen, Xianyong Ma, Miao Yu · 2021 · Frontiers in Immunology
Molecular features of macrophage activation
Joachim Ludwig Schultze, Susanne V. Schmidt · 2015 · Seminars in Immunology
‘Ride on the ferrous wheel’ – The cycle of iron in macrophages in health and disease
Nairz, Manfred, Schroll, Andrea, Demetz, Egon, Tancevski, Ivan, Theurl, Igor, Weiss, Günter · 2015 · Immunobiology
Haptoglobin Therapeutics and Compartmentalization of Cell-Free Hemoglobin Toxicity
Paul W. Buehler, Rok Humar, Dominik J. Schaer · 2020 · Trends in Molecular Medicine
Mechanism of colorectal carcinogenesis triggered by heme iron from red meat
Nina Seiwert, Daniel Heylmann, Solveig Hasselwander, Jörg Fahrer · 2019 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
The impact of metal availability on immune function during infection
Monteith, Andrew J., Skaar, Eric P. · 2021 · Trends in Endocrinology & Metabolism
The Mononuclear Phagocytic System. Generation of Diversity
Siamon Gordon, Annette Plüddemann · 2019 · Frontiers in Immunology
Inflammation induces stress erythropoiesis through heme-dependent activation of SPI-C
Laura F. Bennett, Chang Liao, Michael D. Quickel, Beng San Yeoh, Matam Vijay–Kumar, Pamela Hankey‐Giblin, K. Sandeep Prabhu, Robert F. Paulson · 2019 · Science Signaling
Fetal liver endothelium regulates the seeding of tissue-resident macrophages
Pia Rantakari, Norma Jäppinen, Emmi Lokka, Elias Mokkala, Heidi Gerke, Emilia Peuhu, Johanna Ivaska, Kati Elima, Kaisa Auvinen, Marko Salmi · 2016 · Nature
Distinct microenvironmental cues stimulate divergent TLR4-mediated signaling pathways in macrophages
Anna Maria Piccinini, Lorena Zuliani‐Alvarez, Jenny M. P. Lim, Kim S. Midwood · 2016 · Science Signaling
Iron and zinc exploitation during bacterial pathogenesis
Li Maria Ma, Austen Lee Terwilliger, Anthony William Maresso · 2015 · Metallomics
Origin and specialization of splenic macrophages
Noelia A-González, Antonio Castrillo · 2018 · Cellular Immunology
Reprogramming of macrophages — new opportunities for therapeutic targeting
Joachim Ludwig Schultze · 2015 · Current Opinion in Pharmacology
Hemolysis transforms liver macrophages into antiinflammatory erythrophagocytes
Marc Pfefferlé, Giada Ingoglia, Christian A. Schaer, Ayla Yalamanoglu, Raphael M. Buzzi, Irina L. Dubach, Ge Tan, Emilio Yangüez López-Cano, Nadja Schulthess-Lutz, Kerstin Hansen et al. · 2020 · Journal of Clinical Investigation
Tissue Iron Promotes Wound Repair via M2 Macrophage Polarization and the Chemokine (C-C Motif) Ligands 17 and 22
Holly Nicola Wilkinson, Elizabeth Rose Roberts, Amber R. Stafford, Kayleigh L. Banyard, Paolo Luciano Matteucci, Kimberly A. Mace, Matthew J. Hardman · 2019 · American Journal Of Pathology
Monocytes, Macrophages, and Their Potential Niches in Synovial Joints – Therapeutic Targets in Post-Traumatic Osteoarthritis?
Patrick Haubruck, Marlène Magalhaes Pinto, Babak Moradi, Christopher B. Little, Rebecca Gentek · 2021 · Frontiers in Immunology
Spatiotemporal Adaptations of Macrophage and Dendritic Cell Development and Function
Antoine Roquilly, Justine D. Mintern, Jóse A. Villadangos · 2022 · Annual Review of Immunology
Monocyte-derived macrophages expand the murine stress erythropoietic niche during the recovery from anemia
Chang Liao, K. Sandeep Prabhu, Robert F. Paulson · 2018 · Blood
Specific sequences of infectious challenge lead to secondary hemophagocytic lymphohistiocytosis-like disease in mice
Wang, Andrew, Pope, Scott D., Weinstein, Jason S., Yu, Shuang, Zhang, Cuiling, Booth, Carmen J., Medzhitov, Ruslan · 2019 · Proceedings of the National Academy of Sciences
Fibroblasts and macrophages: Collaborators in tissue homeostasis
Ruth A. Franklin · 2021 · Immunological Reviews
Basic Mechanisms of Hemolysis-Associated Thrombo-Inflammation and Immune Dysregulation
Jordan D. Dimitrov, Lubka T. Roumenina, Gina Perrella, Julie Rayes · 2023 · Arteriosclerosis Thrombosis and Vascular Biology
Transcriptional control of monocyte and macrophage development
Daisuke Kurotaki, Haruka Sasaki, Tomohiko Tamura · 2017 · International Immunology
The estrogen–macrophage interplay in the homeostasis of the female reproductive tract
Giovanna Pepe, Massimo Locati, Sara Della Torre, Federica Mornata, Andrea Cignarella, Adriana C. Maggi, Elisabetta Vegeto · 2018 · Human Reproduction Update
Immune Mechanisms in Inflammatory Anemia
Canny, Susan P., Orozco, Susana L., Thulin, Natalie K., Hamerman, Jessica A. · 2023 · Annual Review of Immunology
Heme Gazing: Illuminating Eukaryotic Heme Trafficking, Dynamics, and Signaling with Fluorescent Heme Sensors
David A. Hanna, Osiris Martinez-Guzman, Amit R. Reddi · 2017 · Biochemistry
Microenvironmental signals govern the cellular identity of testicular macrophages
Andreas Meinhardt, Ming Wang, Christian Schulz, Sudhanshu Bhushan · 2018 · Journal of Leukocyte Biology
The Repair of Skeletal Muscle Requires Iron Recycling through Macrophage Ferroportin
Corna, Gianfranca, Caserta, Imma, Monno, Antonella, Apostoli, Pietro, Manfredi, Angelo A, Camaschella, Clara, Rovere-Querini, Patrizia · 2016 · The Journal of Immunology
The Heme Connection: Linking Erythrocytes and Macrophage Biology
Md. Zahidul Alam, Samir Devalaraja, Malay Haldar · 2017 · Frontiers in Immunology
Heme ameliorates dextran sodium sulfate-induced colitis through providing intestinal macrophages with noninflammatory profiles
Kayama, Hisako, Kohyama, Masako, Okuzaki, Daisuke, Motooka, Daisuke, Barman, Soumik, Okumura, Ryu, Muneta, Masato, Hoshino, Katsuaki, Sasaki, Izumi, Ise, Wataru et al. · 2018 · Proceedings of the National Academy of Sciences
Heme and hemolysis in innate immunity: adding insult to injury
Rui Martins, Sylvia Knapp · 2017 · Current Opinion in Immunology
Counter Regulation of Spic by NF-κB and STAT Signaling Controls Inflammation and Iron Metabolism in Macrophages
Zahidul Alam, Samir Devalaraja, Minghong Li, Tsun Ki Jerrick To, Ian Wesley Folkert, Erick Mitchell-Velasquez, Mai T. Dang, Patricia Ann Young, Christopher J. Wilbur, Michael A. Silverman et al. · 2020 · Cell Reports
Plasticity of monocyte development and monocyte fates
Sébastien Trzebanski, Steffen Jung · 2020 · Immunology Letters
ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection
Dianyuan Zhao, Fengjiao Yang, Yang Wang, Site Li, Yang Li, Fei Hou, Wenting Yang, Di Liu, Yuandong Tao, Qian Li et al. · 2021 · Journal of Clinical Investigation
Inducible mechanisms of disease tolerance provide an alternative strategy of acquired immunity to malaria
Wiebke Nahrendorf, Alasdair C. Ivens, Philip J. Spence · 2021 · eLife
LYVE-1 + Macrophages Form a Collaborative CCR5-Dependent Perivascular Niche That Influences Chemotherapy Responses in Cancer
Joanne E. Anstee, Karen T. Feehan, James W. Opzoomer, Isaac Dean, Henrike P. Muller, M. Bahri, Tik Shing Cheung, Kifayathullah Liakath‐Ali, Ziyan Liu, Desmond Choy et al. · 2022 · Developmental Cell
The Multiple Facets of Iron Recycling
Patryk Slusarczyk, Katarzyna Mleczko‐Sanecka · 2021 · Genes
Erythroblastic Island Macrophages Shape Normal Erythropoiesis and Drive Associated Disorders in Erythroid Hematopoietic Diseases
Wei Li, Rongqun Guo, Yongping Song, Zhongxing Jiang · 2021 · Frontiers in Cell and Developmental Biology
Redox-signals and macrophage biology
Andreas Weigert, Andreas von Knethen, Dominik Christian Fuhrmann, Nathalie Dehne, Bernhard Brüne · 2018 · Molecular Aspects of Medicine
Macrophages Orchestrate Hematopoietic Programs and Regulate HSC Function During Inflammatory Stress
Allison N. Seyfried, Jackson Maloney, K. MacNamara · 2020 · Frontiers in Immunology
Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages
Yuning Lu, Gemma Basatemur, Ian Christopher Scott, Davide Chiarugi, Marc Clément, James E. Harrison, Ravin Jugdaohsingh, Xianjun Yu, Stephen A. Newland, Helen E. Jolin et al. · 2020 · Immunity
Macrophage barrier in the tumor microenvironment and potential clinical applications
Shuai Ji, Yuqing Shi, Bo Yin · 2024 · Cell Communication and Signaling
Hemolysis and immune regulation
Hui Zhong, Karina Yazdanbakhsh · 2018 · Current Opinion in Hematology
Growth Factors as Immunotherapeutic Targets in Cardiovascular Disease
John E. Mindur, Filip K. Świrski · 2019 · Arteriosclerosis Thrombosis and Vascular Biology
Tissue-Resident Macrophages in Fungal Infections
Xu, Shengjie, Shinohara, Mari L. · 2017 · Frontiers in Immunology
Global landscape of mouse and human cytokine transcriptional regulation
Sebastian Carrasco Pro, Alvaro Dafonte Imedio, Clarissa Stephanie Santoso, Kok Ann Gan, Jared Allan Sewell, Melissa Martinez, Rebecca Sereda, Shivani M Mehta, Juan I. Fuxman Bass · 2018 · Nucleic Acids Research
Macrophage Subsets in Obesity, Aligning the Liver and Adipose Tissue
Anneleen Remmerie, Liesbet Martens, Charlotte L. Scott · 2020 · Frontiers in Endocrinology
Epigenetic Regulation of Kupffer Cell Function in Health and Disease
Bennett, Hunter, Troutman, Ty D., Sakai, Mashito, Glass, Christopher K. · 2021 · Frontiers in Immunology
Cell‐type‐specific insights into iron regulatory processes
Katarzyna Mleczko‐Sanecka, Laura Silvestri · 2020 · American Journal of Hematology
Prolonged fasting drives a program of metabolic inflammation in human adipose tissue
Pouneh K. Fazeli, Yang Zhang, John O’Keefe, Tristan Pesaresi, Mingyue Lun, Brian P. Lawney, Matthew L. Steinhauser · 2020 · Molecular Metabolism
Iron Handling in Tumor-Associated Macrophages—Is There a New Role for Lipocalin-2?
Michaela Jung, Andreas Weigert, Christina Mertens, Claudia Rehwald, Bernhard Brüne · 2017 · Frontiers in Immunology
EP3 enhances adhesion and cytotoxicity of NK cells toward hepatic stellate cells in a murine liver fibrosis model
Xixi Tao, Rui Zhang, Ronglu Du, Tingting Yu, Hui Yang, Jiwen Li, Yuhong Wang, Qian Liu, Shengkai Zuo, Xi Wang et al. · 2022 · The Journal of Experimental Medicine
CSF1R regulates the dendritic cell pool size in adult mice via embryo-derived tissue-resident macrophages
Gülce Itır Perçin, Jiří Eitler, Andrea Kranz, Jun Fu, Jeffrey W. Pollard, Ronald Naumann, Claudia Waskow · 2018 · Nature Communications
Understanding macrophage diversity at the ontogenic and transcriptomic levels
Emmanuel L. Gautier, Laurent Yvan‐Charvet · 2014 · Immunological Reviews
Type I interferon is induced by hemolysis and drives antibody-mediated erythrophagocytosis in sickle cell disease
Yunfeng Liu, Mouli Pal, Weili Bao, Patricia Ann Shi, Cheryl A. Lobo, Xiuli An, Deepa G. Manwani, Hui Zhong, Karina Yazdanbakhsh · 2021 · Blood
Selenoproteins regulate stress erythroid progenitors and spleen microenvironment during stress erythropoiesis
Chang Liao, Ross C. Hardison, Mary J. Kennett, Bradley Allen Carlson, Robert F. Paulson, K. Sandeep Prabhu · 2018 · Blood
Nature and nurture of tissue-specific macrophage phenotypes
Marten A. Hoeksema, Christopher K. Glass · 2018 · Atherosclerosis
Thymic macrophages consist of two populations with distinct localization and origin
Tyng-An Zhou, Hsuan-Po Hsu, Yueh-Hua Tu, Hui-Kuei Cheng, Chih‐Yu Lin, Nien‐Jung Chen, Jin‐Wu Tsai, Ellen A. Robey, Hsuan‐Cheng Huang, Chia‐Lin Hsu et al. · 2022 · eLife
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours
Samarth Hegde, B. Giotti, Brian Y. Soong, Laszlo Halasz, Jessica Le Berichel, Maximilian M. Schaefer, Benoît Kloeckner, R. Mattiuz, Matthew D. Park, A. Magen et al. · 2025 · Nature
Biology of Heme in Mammalian Erythroid Cells and Related Disorders
Tohru Fujiwara, Hideo Harigae · 2015 · BioMed Research International
Gdf15 regulates murine stress erythroid progenitor proliferation and the development of the stress erythropoiesis niche
Siyang Hao, Jie Xiang, Dai-Chen Wu, James W. Fraser, Baiye Ruan, Jingwei Cai, Andrew D. Patterson, Zhi-Chun Lai, Robert F. Paulson · 2019 · Blood Advances
Hemozoin produced by mammals confers heme tolerance
Rini H Pek, Xiaojing Yuan, Nicole Rietzschel, Jianbing Zhang, Laurie K. Jackson, Eiji Nishibori, Ana Cristina Ribeiro, William R. Simmons, Jaya Jagadeesh, Hiroshi Sugimoto et al. · 2019 · eLife
Network Approaches for Dissecting the Immune System
Hao Shi, Koon‐Kiu Yan, Liang Ding, Chenxi Qian, Hongbo Chi, Jiyang Yu · 2020 · iScience
RAG-mediated DNA double-strand breaks activate a cell type–specific checkpoint to inhibit pre–B cell receptor signals
Jeffrey J. Bednarski, Ruchi Pandey, Emily Schulte, Lynn S. White, Bo-Ruei Chen, Gabriel J. Sandoval, Masako Kohyama, Malay Haldar, Andrew Nickless, Amanda Trott et al. · 2016 · The Journal of Experimental Medicine
Essential Role of mTORC1 in Self-Renewal of Murine Alveolar Macrophages
Wenhai Deng, Jialong Yang, Xingguang Lin, Jinwook Shin, Jimin Gao, Xiao‐Ping Zhong · 2016 · The Journal of Immunology
Infection perturbs Bach2- and Bach1-dependent erythroid lineage ‘choice’ to cause anemia
Hiroki Kato, Ari Itoh‐Nakadai, Mitsuyo Matsumoto, Yusho Ishii, Miki Watanabe‐Matsui, Masatoshi Ikeda, Risa Ebina‐Shibuya, Yuki Sato, Masahiro Kobayashi, Hironari Nishizawa et al. · 2018 · Nature Immunology
Reduced Iron in Diabetic Wounds: An Oxidative Stress-Dependent Role for STEAP3 in Extracellular Matrix Deposition and Remodeling
Holly Nicola Wilkinson, Sophie E. Upson, Kayleigh L. Banyard, R. Knight, Kimberly A. Mace, Matthew James Hardman · 2019 · Journal of Investigative Dermatology
PPARγ is essential for the development of bone marrow erythroblastic island macrophages and splenic red pulp macrophages
Katarzyna Maria Okreglicka, Irina Iten, Lea Maria Pohlmeier, Lucas Onder, Qian Feng, Michael Odo Kurrer, Burkhard Ludewig, Peter Nielsen, Christoph Schneider, Manfred Köpf · 2021 · The Journal of Experimental Medicine
Heart failure promotes multimorbidity through innate immune memory
Yukiteru Nakayama, Katsuhito Fujiu, Tsukasa Oshima, Jun Matsuda, Junichi Sugita, Takumi James Matsubara, Yuxiang Liu, Kohsaku Goto, Kunihiro Kani, Ryoko Uchida et al. · 2024 · Science Immunology
Transcriptional Regulation of Mononuclear Phagocyte Development
Roxane Tussiwand, Emmanuel L. Gautier · 2015 · Frontiers in Immunology
Bone marrow infiltration by multiple myeloma causes anemia by reversible disruption of erythropoiesis
Anass Bouchnita, Nathalie Eymard, Tamara Kay Moyo, Mark J. Koury, Vitaly A Volpert · 2016 · American Journal of Hematology
Killing Is Not Enough: How Apoptosis Hijacks Tumor-Associated Macrophages to Promote Cancer Progression
Andreas Weigert, Javier Mora, Divya Sekar, Shahzad Nawaz Syed, Bernhard Brüne · 2016 · Advances in experimental medicine and biology
Development and Functional Differentiation of Tissue-Resident Versus Monocyte-Derived Macrophages in Inflammatory Reactions
Paola Italiani, Diana Boraschi · 2017 · Results and problems in cell differentiation
Modulation of Iron Metabolism in Response to Infection: Twists for All Tastes
Ana Cordeiro Gomes, Ana C. Moreira, Gonçalo Mesquita, Maria Salomé Gomes · 2018 · Pharmaceuticals
TLR4 activation alters labile heme levels to regulate BACH1 and heme oxygenase-1 expression in macrophages
Kritika Sudan, Vijith Vijayan, Kukuh Madyaningrana, Faikah Gueler, Kazuhiko Igarashi, Roberta Foresti, Roberto Motterlini, Stephan Immenschuh · 2019 · Free Radical Biology and Medicine
Digesting the role of bone marrow macrophages on hematopoiesis
Esther Heideveld, Emile van den Akker · 2016 · Immunobiology
Human and murine splenic neutrophils are potent phagocytes of IgG-opsonized red blood cells
Sanne M. Meinderts, Per‐Arne Oldenborg, Boukje M. Beuger, Thomas R. L. Klei, Johanna Johansson, Taco Willem Kuijpers, Takashi Matozaki, Elise J. Huisman, Masja de Haas, Timo K. van den Berg et al. · 2017 · Blood Advances
Interplay of Heme with Macrophages in Homeostasis and Inflammation
Pooja Pradhan, Vijith Vijayan, Faikah Gueler, Stephan Immenschuh · 2020 · International Journal of Molecular Sciences
Macrophage‐fibroblast circuits in the spleen
Alicia Bellomo, Rebecca Gentek, Rachel Golub, Marc Bajénoff · 2021 · Immunological Reviews
ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection
Dianyuan Zhao, Fengjiao Yang, Yang Wang, Site Li, Yang Li, Fei Hou, Wenting Yang, Di Liu, Yuandong Tao, Qian Li et al. · 2022 · DOAJ (DOAJ: Directory of Open Access Journals)
MFehi adipose tissue macrophages compensate for tissue iron perturbations in mice
Merla J. Hubler, Keith M. Erikson, Arion J. Kennedy, Alyssa H. Hasty · 2018 · American Journal of Physiology-Cell Physiology
Erythrophagocytes in hemolytic anemia, wound healing, and cancer
Rok Humar, Dominik J. Schaer, Florence Vallelian · 2022 · Trends in Molecular Medicine
Macrophage Regulation of Granulopoiesis and Neutrophil Functions
Christian Schulz, Tobias Petzold, Hellen Cristina Ishikawa-Ankerhold · 2020 · Antioxidants and Redox Signaling
Impaired iron recycling from erythrocytes is an early hallmark of aging
Patryk Slusarczyk, Pratik Kumar Mandal, Gabriela Zurawska, Marta Niklewicz, Komal Chouhan, Raghunandan Mahadeva, Aneta Jończy, Matylda Macias, Aleksandra Szybińska, Magdalena Cybulska et al. · 2023 · eLife
Transcription factor BACH1 in cancer: roles, mechanisms, and prospects for targeted therapy
Dian Xing Hu, Zerui Zhang, Xiangyuan Luo, Siwen Li, Junqing Jiang, Jiaqian Zhang, Zhangfan Wu, Yijun Wang, Mengyu Sun, Xiaoping Chen et al. · 2024 · Biomarker Research
The Macrophage Iron Signature in Health and Disease
Christina Mertens, Oriana Marques, Natalie K. Horvat, Manuela Simonetti, Martina Ulrike Muckenthaler, Michaela Jung · 2021 · International Journal of Molecular Sciences
Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibitors and Iron Metabolism
Chie Ogawa, Ken Tsuchiya, Kunimi Maeda · 2023 · International Journal of Molecular Sciences
Gadolinium toxicity: Iron and ferroportin as central targets
Sundararaman Swaminathan · 2016 · Magnetic Resonance Imaging
Origin and function of synovial macrophage subsets during inflammatory joint disease
Stephan Culemann, Anika Grüneboom, Gerhard Krönke · 2019 · Advances in immunology
Heme protects intestinal mucosal barrier in DSS‐induced colitis through regulating macrophage polarization in both HO‐1‐dependent and HO‐1‐independent way
Yanwei Wu, Bing Wu, Zongwang Zhang, Huimin Lu, Chen Fan, Qing Qi, Yuanzhuo Gao, Heng Li, Chunlan Feng, Jianping Zuo et al. · 2020 · The FASEB Journal
Comprehensive mapping of the human cytokine gene regulatory network
Clarissa Stephanie Santoso, Zhaorong Li, Sneha Lal, Samson Yuan, Kok Ann Gan, Luis M. Agosto, Xing Liu, Sebastian Carrasco Pro, Jared Allan Sewell, Andrew J. Henderson et al. · 2020 · Nucleic Acids Research
Multiarm-Assisted Design of Dendron-like Degradable Ionizable Lipids Facilitates Systemic mRNA Delivery to the Spleen
Lulu Xue, Xinhong Xiong, Gan Zhao, William A. Molina Arocho, Rohan Palanki, Zebin Xiao, Xuexiang Han, Il‐Chul Yoon, Christian G. Figueroa‐Espada, Junchao Xu et al. · 2025 · Journal of the American Chemical Society
Iron and the immune system
Joe N. Frost, Hal Drakesmith · 2025 · Nature reviews. Immunology
Desynchronization of the molecular clock contributes to the heterogeneity of the inflammatory response
Nancy C. Allen, Naomi H. Philip, Lucy Hui, Xu Zhou, Ruth A. Franklin, Yong Kong, Ruslan M. Medzhitov · 2019 · Science Signaling
Vitamin D3-vitamin D receptor axis suppresses pulmonary emphysema by maintaining alveolar macrophage homeostasis and function
Guangan Hu, Ting Dong, Sisi Wang, Hongyu Jing, Jianzhu Chen · 2019 · EBioMedicine