The DOI matches its Crossref record; 27 of the 27 references it cites were found in a registry or an index.
Individualized Medicine from Prewomb to Tomb
Open accessAbstract
That each of us is truly biologically unique, extending to even monozygotic, “identical” twins, is not fully appreciated. Now that it is possible to perform a comprehensive “omic” assessment of an individual, including one's DNA and RNA sequence, and at least some characterization of one's proteome, metabolome, microbiome, autoantibodies, and epigenome, it has become abundantly clear that each of us has truly one-of-a-kind biological content. Well beyond the allure of the matchless fingerprint or snowflake concept, these singular, individual data and information set up a remarkable and unprecedented opportunity to improve medical treatment and develop preventive strategies to preserve health.
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Cites
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Ginsburg, G. S., & Phillips, K. A. (2018) · Health Affairs · doi:10.1377/hlthaff.2017.1624 · Cited by 759
Health information technology and digital innovation for national learning health and care systems
Sheikh, A., Anderson, M., Albala, S., Casadei, B., Franklin, B. D., Richards, M., Taylor, D., Tibble, H., & Mossialos, E. (2021) · The Lancet Digital Health · doi:10.1016/s2589-7500(21)00005-4 · Cited by 389
Axes of a revolution: challenges and promises of big data in healthcare
Shilo, S., Rossman, H., & Segal, E. (2020) · Nature Medicine · doi:10.1038/s41591-019-0727-5 · Cited by 370
Analysis of 589,306 genomes identifies individuals resilient to severe Mendelian childhood diseases
Chen, R., Shi, L., Hakenberg, J., Naughton, B., Sklar, P., Zhang, J., Zhou, H., Tian, L., Prakash, O., Lemire, M., et al. (2016) · Nature Biotechnology · doi:10.1038/nbt.3514 · Cited by 310
Metadata
- Authors
- Topol, E. J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2014-03
- Volume
- 157
- Issue
- 1
- Pages
- 241-253
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2090657329
- Cited by
- 333
- References
- 27
- FWCI
- 22.19
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
