Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome

Yan, Yiqing, Jiang, Wei, Liu, Lei, Wang, Xiaqiong, Ding, Chen, Tian, Zhigang, Zhou, Rongbin·2015·Cell

DOI 10.1016/j.cell.2014.11.047

Cited by (1,000)

Items 501–600 of 1,000

Posttreatment of Maresin1 Inhibits NLRP3 inflammasome activation via promotion of NLRP3 ubiquitination
Sisi Zheng, Minqi Ma, Zhong-wang Li, Hao Yu, Hui Li, Panhan Fu, Shengwei Jin · 2020 · The FASEB Journal
Anti-NLRP3 Inflammasome Natural Compounds: An Update
Bao-Long Liu, Jiu-Jiu Yu · 2021 · Biomedicines
Resolvin D2 suppresses NLRP3 inflammasome by promoting autophagy in macrophages
Lijun Cao, Yiya Wang, Yina Wang, Feijuan Lv, Lixiu Liu, Zhen Li · 2021 · Experimental and Therapeutic Medicine
The mechanism behind activation of the Nod-like receptor family protein 3 inflammasome in Parkinson’s disease
Anmu Xie, Jing Wang, Xiaona Zhang, Jin-Ni Fang, Fei-Fei Hua, Jing-Yang Han, Zengqiang Yuan · 2021 · Neural Regeneration Research
Circulating Inflammation Proteins Associated With Lung Cancer in African Americans
Claire L. Meaney, Khadijah A. Mitchell, Adriana Zingone, Derek W. Brown, Elise D. Bowman, Yunkai Yu, Angela S. Wenzlaff, Christine M Neslund-Dudas, Sharon R. Pine, Liang Cao et al. · 2019 · Journal of Thoracic Oncology
Recent advances of nanomaterials for intervention in Parkinson’s disease in the context of anti-inflammation
Ruoyu Zhang, Xiaotong Chen, Yuanyuan Cheng, Zixuan Chen, Xiaoqiong Li, Yulin Deng · 2023 · Coordination Chemistry Reviews
Emodin attenuates adenosine triphosphate‑induced pancreatic ductal cell injury in vitro via the inhibition of the P2X7/NLRP3 signaling pathway
Qingkai Zhang, Fenglin Hu, Fangyue Guo, Qi Zhou, Hong Xiang, Dong Shang · 2019 · Oncology Reports
Dopaminergic impact of cART and anti-depressants on HIV neuropathogenesis in older adults
Stephanie M. Matt, Peter J. Gaskill · 2019 · Brain Research
Sex-specific effects of developmental exposure to polychlorinated biphenyls on neuroimmune and dopaminergic endpoints in adolescent rats
Deborah A. Liberman, Katherine A. Walker, Andrea C. Gore, Margaret R. Bell · 2020 · Neurotoxicology and Teratology
Modulating the immune response with the wake-promoting drug modafinil: A potential therapeutic approach for inflammatory disorders
Adriano Zager · 2020 · Brain Behavior and Immunity
Role of interleukin-1 and inflammasomes in oral disease
Tomohiko Murakami, Yoshifumi Takahata, Kenji Hata, Riko Nishimura · 2020 · Journal of Oral Biosciences
PARK2 attenuates house dust mite-induced inflammatory reaction, pyroptosis and barrier dysfunction in BEAS-2B cells by ubiquitinating NLRP3.
Xiahui Ge, Feng Cai, Yan Shang, Feng Chi, Hua Xiao, Jing Xu, Youhui Fu, Chong Bai · 2021 · Europe PMC (PubMed Central)
The Heteromeric Complex Formed by Dopamine Receptor D5 and CCR9 Leads the Gut Homing of CD4+ T Cells Upon Inflammation
Francisco Osorio‐Barrios, Gemma Navarro, Javier Campos, Valentina Ugalde, Carolina E. Prado, Iu Raïch, Francisco Contreras, Ernesto López, Alexandra Espinoza, Álvaro Lladser et al. · 2021 · Cellular and Molecular Gastroenterology and Hepatology
Endogenous Regulation and Pharmacological Modulation of Sepsis-Induced HMGB1 Release and Action: An Updated Review
Shu Zhu, Wei Wang, Xiaoling Qiang, Weiqiang Chen, Xiqian Lan, Jianhua Li, Haichao Wang · 2021 · Cells
The wake-promoting drug Modafinil prevents motor impairment in sickness behavior induced by LPS in mice: Role for dopaminergic D1 receptor
Adriano Zager, Wesley Nogueira Brandão, Rafael Oliveira Margatho, Jean Pierre Schatzmann Peron, Sérgio Tufik, Mônica L. Andersen, Birgitte Rahbek Kornum, João Palermo‐Neto · 2017 · Progress in Neuro-Psychopharmacology and Biological Psychiatry
Inhibition of NLRP3 inflammasome: a new protective mechanism of cinnamaldehyde in endotoxin poisoning of mice
Feng Xu, Feng Wang, Taoqun Wen, Wentao Sang, Dejian Wang, Nan Zeng · 2017 · Immunopharmacology and Immunotoxicology
Salmeterol, agonist of β2-aderenergic receptor, prevents systemic inflammation via inhibiting NLRP3 inflammasome
Nanshan Song, Yinquan Fang, Xiyang Sun, Qingling Jiang, Chenghuan Song, Miaomiao Chen, Jianhua Ding, Ming Lu, Gang Hu · 2018 · Biochemical Pharmacology
A potential mechanistic role for neuroinflammation in reward processing impairments in autism spectrum disorder
Rachel K. Greene, Erin C. Walsh, Maya G. Mosner, Gabriel S. Dichter · 2018 · Biological Psychology
Dopamine D1 receptor alleviates doxorubicin-induced cardiac injury by inhibiting NLRP3 inflammasome
Jiao Liu, Yuxuan Jin, Bei Wang, Yiran Wang, Shengkai Zuo, Jinying Zhang · 2021 · Biochemical and Biophysical Research Communications
Brain nuclei and neural circuits in neuropathic pain and brain modulation mechanisms of acupuncture: a review on animal-based experimental research
Na Su, Pingping Cai, Zhiqiang Dou, Xiaoxue Yin, Hongmin Xu, Jing He, Zhaofeng Li, Changzhong Li · 2023 · Frontiers in Neuroscience
Echinacoside exerts neuroprotection via suppressing microglial α-synuclein/TLR2/NF-κB/NLRP3 axis in parkinsonian models
Xueping Yang, Jia-Hua Huang, Fanlong Ye, Qingyun Yv, Sheng Chen, Wen-Wei Li, Min Zhu · 2023 · Phytomedicine
Melatonin prevents sepsis-induced renal injury via the PINK1/Parkin1 signaling pathway
Wenling Dai, Haifeng Huang, Linjie Si, Shi Hu, Liangliang Zhou, Lingling Xu, Yijun Deng · 2019 · International Journal of Molecular Medicine
Role of G Protein-Coupled Receptors in Microglial Activation: Implication in Parkinson’s Disease
Chao Gu, Yajing Chen, Yan Chen, Chun‐Feng Liu, Zengyan Zhu, Mei Wang · 2021 · Frontiers in Aging Neuroscience
Angiotensin Type-1 Receptor Inhibition Reduces NLRP3 Inflammasome Upregulation Induced by Aging and Neurodegeneration in the Substantia Nigra of Male Rodents and Primary Mesencephalic Cultures
Aloia Quijano, Carmen Díaz-Ruiz, Andrea López-López, Begoña Villar‐Cheda, Ana Muñoz, Ana Isabel Rodriguez-Perez, José Luis Labandeira-García · 2022 · Antioxidants
Munronoid I Ameliorates DSS-Induced Mouse Colitis by Inhibiting NLRP3 Inflammasome Activation and Pyroptosis Via Modulation of NLRP3
Xingyu Ma, Qianqian Di, Xiaoli Li, Xibao Zhao, Ruihan Zhang, Yue Xiao, Xunwei Li, Han Wu, Haimei Tang, Jiazheng Quan et al. · 2022 · Frontiers in Immunology
Repeated Domperidone treatment modulates pulmonary cytokines in LPS-induced acute lung injury in mice
Talita Rossetto Barreto, Carolina Costola-de-Souza, Rafael Oliveira Margatho, Nicolle Queiroz‐Hazarbassanov, Sandra Campos Rodrigues, Luciano Freitas Felício, João Palermo‐Neto, Adriano Zager · 2018 · International Immunopharmacology
NLRP3 inflammasome pathway is involved in olfactory bulb pathological alteration induced by MPTP
Ying Chen, Qiu-Shuang Zhang, Qian-Hang Shao, Shuo Wang, Yu‐He Yuan, Nai‐Hong Chen, Hongbo Wang · 2019 · Acta Pharmacologica Sinica
NLRP3, un inflammasome sous contrôle
Marine Groslambert, Bénédicte F. Py · 2018 · médecine/sciences
Single hormone or synthetic agonist induces G s /G i coupling selectivity of EP receptors via distinct binding modes and propagating paths
Shen-Ming Huang, Meng-Yao Xiong, Lei Liu, Jianqiang Mu, Ming-Wei Wang, Yingli Jia, Kui Cai, Lu Tie, Chao Zhang, Sheng Cao et al. · 2023 · Proceedings of the National Academy of Sciences
The dopamine analogue CA140 alleviates AD pathology, neuroinflammation, and rescues synaptic/cognitive functions by modulating DRD1 signaling or directly binding to Abeta
Sehyun Chae, Hyunju Lee, Ha-Eun Lee, Ji‐Eun Kim, Yoo Joo Jeong, Yuxi Lin, Hye Yun Kim, Geoffray Leriche, Rachel S. Ehrlich, Sascha Castro Lingl et al. · 2024 · Journal of Neuroinflammation
Is Targeting the Inflammasome a Way Forward for Neuroscience Drug Discovery?
Tessa Swanton, James Cook, James A. Beswick, Sally Freeman, Catherine B. Lawrence, David Brough · 2018 · SLAS DISCOVERY
Cutting Edge: G Protein Subunit β 1 Negatively Regulates NLRP3 Inflammasome Activation
Tomohiko Murakami, Lerdluck Ruengsinpinya, Eriko Nakamura, Yoshifumi Takahata, Kenji Hata, Hiroaki Okae, Shun’ichiro Taniguchi, Masafumi Takahashi, Riko Nishimura · 2019 · The Journal of Immunology
Slc6a3-dependent expression of a CAPS-associated Nlrp3 allele results in progressive behavioral abnormalities and neuroinflammation in aging mice
Katharine M. von Herrmann, Faith L. Anderson, Eileen M. Martinez, Alison L. Young, Matthew C. Havrda · 2020 · Journal of Neuroinflammation
Role of Pyroptosis in Respiratory Diseases and its Therapeutic Potential
Jingjing Liu, Guoqing Fan, Ningning Tao, Tieying Sun · 2022 · Journal of Inflammation Research
Neuroprotective effects of fermented yak milk-derived peptide LYLKPR on H 2 O 2 -injured HT-22 cells
Yunlong Jiang, Yuan Qi, Xiaoting Liu, Fang Li, Yawen Gao, Chunlei Liu, Dan Wu, Xiyan Wang, Fanrui Zhao, Ji Wang et al. · 2022 · Food & Function
Applications of Polydopamine in Implant Surface Modification
Ting Ma, Chen‐Xi Wang, Xi‐Yuan Ge, Yu Zhang · 2023 · Macromolecular Bioscience
Dopamine enhances duodenal epithelial permeability via the dopamine D5 receptor in rodent
Xiao‐Yan Feng, D.‐N. Zhang, Yijie Wang, R.‐F. Fan, F. Hong, Ying Zhang, Yan Li, Jin‐Xia Zhu · 2016 · Acta Physiologica
The protective effect of dopamine on ventilator-induced lung injury via the inhibition of NLRP3 inflammasome
Xiaomei Yang, Xiaotong Sun, Hongli Chen, Guangmin Xi, Yonghao Hou, Jianbo Wu, Dejie Liu, Huanliang Wang, Yuedong Hou, Jingui Yu · 2017 · International Immunopharmacology
The mitochondrial protease HtrA2 restricts the NLRP3 and AIM2 inflammasomes
Ian Gaël Rodrigue‐Gervais, Karine Doiron, Claudia Champagne, Lindsey Mayes, Gabriel André Leiva‐Torres, Paulin Vanié, Todd Douglas, Silvia Marina Vidal, Emad S. Alnemri, Maya Saleh · 2018 · Scientific Reports
Ticagrelor Increases SIRT1 and HES1 mRNA Levels in Peripheral Blood Cells from Patients with Stable Coronary Artery Disease and Chronic Obstructive Pulmonary Disease
Giorgio Aquila, Francesco Vieceli Dalla Sega, Luisa Marracino, Rita Pavasini, Laura Sofia Cardelli, Anna Piredda, Alessandra Scoccia, Valeria Martino, Francesca Fortini, Ilaria Bononi et al. · 2020 · International Journal of Molecular Sciences
Dopamine D1 receptor agonist A68930 attenuates acute kidney injury by inhibiting NLRP3 inflammasome activation
Jing-Yuan Cao, Le‐Ting Zhou, Zuo‐Lin Li, Yan Yang, Bi‐Cheng Liu, Hong Liu · 2020 · Journal of Pharmacological Sciences
Forskolin attenuates the NLRP3 inflammasome activation and IL-1β secretion in human macrophages
Yan Chen, Jianguo Wen, Jin Jin Feng, Yi He Wang, Tian Fang Li, Katariina Nurmi, Kari K. Eklund, Dong Ming Xing · 2019 · Pediatric Research
Small dose of L-dopa/Benserazide hydrochloride improved sepsis-induced neuroinflammation and long-term cognitive dysfunction in sepsis mice
Fan Li, Bin Zhang, Shangchun Duan, Wenxiang Qing, Longjiao Tan, Shanshan Chen, Yi Wang, Dan Li, Jing Yang, Jianbin Tong et al. · 2020 · Brain Research
Cyclic nucleotide phosphodiesterase 1C contributes to abdominal aortic aneurysm
Chongyang Zhang, Hongmei Zhao, Yujun Cai, Jian Xiong, Amy M. Mohan, Danfei Lou, Hangchuan Shi, Yishuai Zhang, Xiaochun Long, Jing Wang et al. · 2021 · Proceedings of the National Academy of Sciences
Monitoring Substantia Nigra Degeneration Using Free Water Imaging across Prodromal and Clinical Parkinson's Disease
Gaiyan Zhou, Jingru Ren, Danyan Rong, Hao Zhou, Houxu Ning, Hui Wang, Chenxi Pan, Yajie Wang, Ronggui Zhang, Zhiying Guo et al. · 2023 · Movement Disorders
Photothermal Controlled‐Release Immunomodulatory Nanoplatform for Restoring Nerve Structure and Mechanical Nociception in Infectious Diabetic Ulcers
Le Jiang, Xiangyi Wu, Yifan Wang, Chunlin Liu, Yixian Wu, Jingyun Wang, Nan Xu, Zhijun He, Shuqin Wang, Hao Zhang et al. · 2023 · Advanced Science
Dopamine D1 receptor agonist A-68930 inhibits NLRP3 inflammasome activation and protects rats from spinal cord injury-induced acute lung injury
Wei Jiang, Mao-Qiang Li, Fan He, Z. Bian, J. Liu, Qi-Fang He, Xue-Peng Wang, T. Sun, Liu-Long Zhu · 2016 · Spinal Cord
Opportunities for future therapeutic interventions for hyperoxaluria: targeting oxidative stress
Sunil N Joshi, Saeed R. Khan · 2019 · Expert Opinion on Therapeutic Targets
Apolipoprotein E (ApoE) orchestrates adipose tissue inflammation and metabolic disorders through NLRP3 inflammasome
Yulin Zhang, Ziwei Cheng, Liyu Hong, Jia Liu, Xinyue Ma, Wenjing Wang, Ran Pan, Wenjie Lu, Qichao Luo, Shan Gao et al. · 2023 · Molecular Biomedicine
A new perspective on the regulation of neuroinflammation in intracerebral hemorrhage: mechanisms of NLRP3 inflammasome activation and therapeutic strategies
Kai-long He, Xianjun Yu, Lei Xia, Yandong Xie, Enbo Qi, Liang Wan, Xuming Hua, Chaohui Jing · 2025 · Frontiers in Immunology
Papaverine Exerts Neuroprotective Effect by Inhibiting NLRP3 Inflammasome Activation in an MPTP-Induced Microglial Priming Mouse Model Challenged with LPS
Yea‐Hyun Leem, Jin‐Sun Park, Jung‐Eun Park, Do‐Yeon Kim, Hee-Sun Kim · 2021 · Biomolecules & Therapeutics
Dopaminergic Receptor Targeting in Multiple Sclerosis: Is There Therapeutic Potential?
Mikhail Melnikov, Mikhail V. Pashenkov, Alexey Boyко · 2021 · International Journal of Molecular Sciences
DJ-1 Alleviates Neuroinflammation and the Related Blood-Spinal Cord Barrier Destruction by Suppressing NLRP3 Inflammasome Activation via SOCS1/Rac1/ROS Pathway in a Rat Model of Traumatic Spinal Cord Injury
Lingxin Cai, Liansheng Gao, Guoqiang Zhang, Hanhai Zeng, Xinyan Wu, Xiaoxiao Tan, Cong Qian, Gao Chen · 2022 · Journal of Clinical Medicine
Negative Feedback of the cAMP/PKA Pathway Regulates the Effects of Endoplasmic Reticulum Stress-Induced NLRP3 Inflammasome Activation on Type II Alveolar Epithelial Cell Pyroptosis as a Novel Mechanism of BLM-Induced Pulmonary Fibrosis
Qiaohui Hong, Yue Zhang, Weixian Lin, Wei Wang, Yafei Yuan, Jiajia Lin, Zhanzhan Xie, Xu Li, Ying Meng · 2022 · Journal of Immunology Research
Role of Microglia in Psychostimulant Addiction
Maria Carolina Machado da Silva, Lia P. Iglesias, Eduardo Candelario‐Jalil, Habibeh Khoshbouei, Fabrício A. Moreira, Antônio Carlos Pinheiro de Oliveira · 2022 · Current Neuropharmacology
MafB regulates NLRP3 inflammasome activation by sustaining p62 expression in macrophages
Huachun Cui, Sami Banerjee, Na Xie, Tapan Dey, Rui-Ming Liu, Yan Y. Sanders, Gang Liu · 2023 · Communications Biology
Sensitivity to targeted UBA1 inhibition in a myeloid cell line model of VEXAS syndrome
Adriana Chiaramida, Sandra G. Obwar, Anja E. H. Nordstrom, Maria Ericsson, Aisha L. Saldanha, Elena V. Ivanova, Gabriel Kenneth Griffin, Dilshad H. Khan, Roger Belizaire · 2023 · Blood Advances
Rasagiline, an inhibitor of MAO ‐B, decreases colonic motility through elevating colonic dopamine content
Caixia Liu, X.‐L. Zhang, Li Zhou, T. Wang, Zhentan Quan, Yuelu Zhang, Junfa Li, Gui-wei LI, Li‐Fei Zheng, L.‐S. Li et al. · 2018 · Neurogastroenterology & Motility
Electroacupuncture alleviates intestinal inflammation and barrier dysfunction by activating dopamine in a rat model of intestinal ischaemia
Yumeng Li, Guochen Xu, Sen Hu, Hong Mei Wu, Yuelong Dai, Wen‐Hua Zhang, Fubo Tang, Hongmin Luo, Xian Shi · 2020 · Acupuncture in Medicine
Activation of Dopamine D2 Receptor Alleviates Neuroinflammation in a Mouse Model of Allergic Rhinitis With Olfactory Dysfunction
Peiqiang Liu, Danxue Qin, Hao Lv, Wenjun Fan, Fangwei Zhou, Ziang Gao, Zezhang Tao, Yu Xu · 2021 · Allergy Asthma and Immunology Research
Ubiquitinated gasdermin D mediates arsenic-induced pyroptosis and hepatic insulin resistance in rat liver
Yuhan Zhu, Jingyuan Zhang, Xiaofeng Yao, Tianming Qiu, Liping Jiang, Ningning Wang, Yan Shi, Chenbing Wu, Weizhuo Yuan, Guang Yang et al. · 2021 · Food and Chemical Toxicology
Microbiome-metabolome analysis reveals alterations in the composition and metabolism of caecal microbiota and metabolites with dietary Enteromorpha polysaccharide and Yeast glycoprotein in chickens
Teketay Wassie, Bei Cheng, Tiantian Zhou, Lumin Gao, Zhuang Lu, Chunyan Xie, Xin Wu · 2022 · Frontiers in Immunology
Therapeutic Potential of Dopamine and Related Drugs as Anti-Inflammatories and Antioxidants in Neuronal and Non-Neuronal Pathologies
Cindy Bandala, Noemí Cárdenas‐Rodríguez, Julieta Griselda Mendoza‐Torreblanca, Itzel Jatziri Contreras‐García, Valentín Martínez-López, Teresita Rocío Cruz-Hernández, Jazmín Carro-Rodríguez, Marco Antonio Vargas-Hernández, Iván Ignacio‐Mejía, Alfonso Alfaro-Rodríguez et al. · 2023 · Pharmaceutics
Dopamine–mediated immunomodulation affects choroid plexus function
Giulia Castellani, Gabriella Contarini, Maddalena Mereu, Ennio Albanesi, Céline Devroye, Claudio D’Amore, Valentina Ferretti, Sara De Martin, Francesco Papaleo · 2019 · Brain Behavior and Immunity
Acetylation is required for NLRP3 self-aggregation and full activation of the inflammasome
Kai Zhao, Yening Zhang, Xueming Xu, Liping Liu, Lingmin Huang, Ruiheng Luo, Jing Li, Ningjie Zhang, Ben Lü · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
LncRNA KCNQ1OT1 promotes NLRP3 inflammasome activation in Parkinson's disease by regulating pri-miR-186/mature miR-186/NLRP3 axis
Meng-Meng Li, Mei-Juan Shi, Chen-Chen Feng, Zhongyu Yu, Xiaofei Bai, † Lulu · 2024 · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease
Ubiquitination in pyroptosis pathway: A potential therapeutic target for sepsis
Yan Liao, Wangzheqi Zhang, Miao Zhou, Chenglong Zhu, Zui Zou · 2024 · Cytokine & Growth Factor Reviews
Recent progress regarding the role of autophagy in cardiac disease
Yasuhiro Maejima, Allen Sam Titus, Daniela Zablocki, Junichi Sadoshima · 2025 · Cardiovascular Research
In Vivo Metabolic Response upon Exposure to Gold Nanorod Core/Silver Shell Nanostructures: Modulation of Inflammation and Upregulation of Dopamine
Haiyun Li, Tao Wen, Tao Wang, Yinglu Ji, Yaoyi Shen, Jiaqi Chen, Haiyan Xu, Xiaochun Wu · 2020 · International Journal of Molecular Sciences
Shedding Light on the Role of Neurotransmitters in the Microenvironment of Pancreatic Cancer
Yiyi Liang, Huimin Li, Yu Gan, Hong Tu · 2021 · Frontiers in Cell and Developmental Biology
“Reframing” dopamine signaling at the intersection of glial networks in the aged Parkinsonian brain as innate Nrf2/Wnt driver: Therapeutical implications
Bianca Marchetti, Carmela Giachino, Cataldo Tirolo, Maria Francesca Serapide · 2022 · Aging Cell
FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system
Yangyang Zhu, Hao Zhang, Huawei Mao, Suqin Zhong, Yubing Huang, Sirong Chen, Kai Yan, Zhibin Zhao, Xiaohan Hao, Yue Zhang et al. · 2022 · Cell Death and Differentiation
Effect of Berberine on Activation of TLR4-NFκB Signaling Pathway and NLRP3 Inflammasome in Patients with Gout
Wantai Dang, Dan Xu, Jingguo Zhou · 2022 · Chinese Journal of Integrative Medicine
Proof-of-Principle Study of Inflammasome Signaling Proteins as Diagnostic Biomarkers of the Inflammatory Response in Parkinson’s Disease
Erika d. l. R. M. Cabrera Ranaldi, Karen Nuytemans, Anisley Martinez, Corneliu C. Luca, Robert W. Keane, Juan Pablo de Rivero Vaccari · 2023 · Pharmaceuticals
In Situ Detection of Neuroinflammation Using Multicellular 3D Neurovascular‐Unit‐on‐a‐Chip
Choi, Jin‐Ha, Choi, Hye Kyu, Lee, Ki‐Bum · 2023 · Advanced Functional Materials
Dopaminergic regulation of inflammation and immunity in Parkinson's disease: friend or foe?
Alessia Furgiuele, Frederico Costa Pereira, Stefano Martini, Franca Marino, Marco Cosentino · 2023 · Clinical & Translational Immunology
Ubiquitination-Mediated Inflammasome Activation during Bacterial Infection
Tao Xu, Yu Guo, Xiaopeng Qi · 2019 · International Journal of Molecular Sciences
Dopamine D1 + D3 receptor density may correlate with parkinson disease clinical features
Pengfei Yang, William C. Knight, Huifangjie Li, Yingqiu Guo, Joel S. Perlmutter, Tammie L.S. Benzinger, John C. Morris, Jinbin Xu · 2020 · Annals of Clinical and Translational Neurology
N-acetyl-chitooligosaccharide attenuates inflammatory responses by suppression of NF-κB signaling, MAPK and NLRP3 inflammasome in macrophages
Haiming Hu, Hui Xia, Xiaojuan Zou, Xinyu Li, Zhigang Zhang, Xiaowei Yao, Mingzhu Yin, Daizhi Tian, Hongtao Liu · 2021 · Journal of Functional Foods
Dopamine Reduces SARS-CoV-2 Replication In Vitro through Downregulation of D2 Receptors and Upregulation of Type-I Interferons
Fiona Limanaqi, Silvia Zecchini, Borana Dino, Sergio Strizzi, Gioia Cappelletti, Olga Utyro, Claudia Vanetti, Micaela Garziano, Irma Saulle, Mario Clerici et al. · 2022 · Cells
Contributions of the Catechol-O-Methyltransferase Val158Met Polymorphism to Changes in Brain Iron Across Adulthood and Their Relationships to Working Memory
Jonatan Gustavsson, Goran Papenberg, Farshad Falahati, Erika J. Laukka, Grégoria Kalpouzos · 2022 · Frontiers in Human Neuroscience
Kv1.3 K + Channel Physiology Assessed by Genetic and Pharmacological Modulation
Tatiana Varanita, Beatrice Angi, Valentina Scattolini, Ildikò Szabó · 2022 · Physiology
Intranasal Rotenone Induces Alpha-Synuclein Accumulation, Neuroinflammation and Dopaminergic Neurodegeneration in Middle-Aged Mice
Monika Sharma, Nishant Sharma, Amit Khairnar · 2022 · Neurochemical Research
Multi-omics analysis reveals BDE47 induces depression-like behaviors in mice by interfering with the 2-arachidonoyl glycerol-associated microbiota-gut-brain axis
Chengqiang Wang, Zou Su, Chun-Guang Dai, Jia‐Le Song, Bo Qian · 2023 · Ecotoxicology and Environmental Safety
Qiji Shujiang granules alleviates dopaminergic neuronal injury of parkinson's disease by inhibiting NLRP3/Caspase-1 pathway mediated pyroptosis
Peng-fei Huan, Xue Sun, Zhu-qing He, Shuai Yang, Li Wang, Hui Xie, Li Wang, Jiancheng He · 2023 · Phytomedicine
Regulation of Cellular Antiviral Signaling by Modifications of Ubiquitin and Ubiquitin-like Molecules
Kang Li, Bo Zhong · 2018 · Immune Network
Inhibition of NLRP3 inflammasome attenuates spinal cord injury‐induced lung injury in mice
Wu Jiang, Maoqiang Li, Fan He, Liulong Zhu · 2018 · Journal of Cellular Physiology
Involvement of dopaminergic signaling in the cross talk between the renin-angiotensin system and inflammation
Javier Campos, R. Pacheco · 2020 · Seminars in Immunopathology
RETRACTED ARTICLE: Tripterine ameliorates monosodium urate crystal-induced gouty arthritis by altering macrophage polarization via the miR-449a/NLRP3 axis
Yu Wang · 2021 · Inflammation Research · Retracted
Mass spectrometry-based proteomic exploration of the human immune system: focus on the inflammasome, global protein secretion, and T cells
Tuula A. Nyman, Martina B. Lorey, Wojciech Cypryk, Sampsa Matikainen · 2017 · Expert Review of Proteomics
An overview of disease models for NLRP3 inflammasome over-activation
Hongliang Zhang, Ayesha Zahid, Hazrat Ismail, Yujie Tang, Tengchuan Jin, Jin‐Hui Tao · 2020 · Expert Opinion on Drug Discovery
Dopamine receptor agonists ameliorate bleomycin-induced pulmonary fibrosis by repressing fibroblast differentiation and proliferation
Yong Mou, Juan Liu, Ting Shuang Pan, Qi Wang, Kang Miao, Yongjian Xu, Weining Xiong, Jun Yu · 2021 · Biomedicine & Pharmacotherapy
Gasdermin D in peripheral nerves: the pyroptotic microenvironment inhibits nerve regeneration
Ye Tao, Fang Wang, Zhaohui Xu, Xianfu Lu, Yanqing Yang, Jing Wu, Changyu Yao, Fangzheng Yi, Jiajia Li, Zhigang Huang et al. · 2021 · Cell Death Discovery
Cilostazol Alleviates NLRP3 Inflammasome–Induced Allodynia/Hyperalgesia in Murine Cerebral Cortex Following Transient Ischemia: Focus on TRPA1/Glutamate and Akt/Dopamine/BDNF/Nrf2 Trajectories
Omnia S. Zaki, Noha Nagah Nassar, Dalaal M. Abdallah, Marwa M. Safar, Reham Atef Mohammed · 2022 · Molecular Neurobiology
Anti-inflammatory effects of acupuncture in the treatment of chronic obstructive pulmonary disease
Linhong Jiang, Peijun Li, Yingqi Wang, Meiling Jiang, Xiaoyu Han, Yidie Bao, Xinliao Deng, Weibing Wu, Xiaodan Liu · 2023 · Journal of Chinese Integrative Medicine
Single-Nucleotide Polymorphism of the MLX Gene Is Associated With Takayasu Arteritis
Natsuko Tamura, Yasuhiro Maejima, Takayoshi Matsumura, Rick B. Vega, Eisuke Amiya, Yusuke Ito, Yuka Shiheido‐Watanabe, Takashi Ashikaga, Issei Komuro, Daniel P. Kelly et al. · 2018 · Circulation Genomic and Precision Medicine
Development of a peptide targeting dopamine transporter to improve ADHD-like deficits
Terence K.Y. Lai, Ping Su, Hailong Zhang, Fang Liu · 2018 · Molecular Brain
Instantaneous depolarization of T cells via dopamine receptors, and inhibition of activated T cells of Psoriasis patients and inflamed human skin, by D1‐like receptor agonist: Fenoldopam
Aviad Keren, Amos Gilhar, Yehuda Ullmann, Marina Frušić‐Zlotkin, Yoram Soroka, Abraham Jacob Domb, Mia Levite · 2019 · Immunology
Inhibition of Microglial GSK3β Activity Is Common to Different Kinds of Antidepressants: A Proposal for an In Vitro Screen to Detect Novel Antidepressant Principles
Kalkman, Hans O. · 2023 · Biomedicines
Molecular mechanisms and therapeutic implications of the sympathetic nervous system in bone-related disorders: a brain-bone axis perspective
Mingdong Liu, Yaqi Liu, Jiayao Yu, Jiaqi Gong, Chunguang Zhao, Zheng Liu · 2025 · Bone Research