The utilization of extracellular proteins as nutrients is suppressed by mTORC1
Palm, Wilhelm, Park, Youngkyu, Wright, Kevin, Pavlova, Natalya N., Tuveson, David A., Thompson, Craig B.·2015·Cell
Cited by (455)
Items 101–200 of 455
- Cross-Talk Between the Tumor Microenvironment, Extracellular Matrix, and Cell Metabolism in CancerMona Nazemi, Elena Rainero · 2020 · Frontiers in Oncology
- Revealing macropinocytosis using nanoparticlesNicolas Means, Chandra Kumar Elechalawar, Wei R. Chen, Resham Bhattacharya, Priyabrata Mukherjee · 2021 · Molecular Aspects of Medicine
- Growth factor signaling to mTORC1 by amino acid–laden macropinosomesYoshida, Sei, Pacitto, Regina, Yao, Yao, Inoki, Ken, Swanson, Joel A. · 2015 · Journal of Cell Biology
- Resistance to mTORC1 Inhibitors in Cancer Therapy: From Kinase Mutations to Intratumoral Heterogeneity of Kinase ActivitySeraina Faes, Nicolas Demartines, Olivier Dormond · 2017 · Oxidative Medicine and Cellular Longevity
- First we eat, then we do everything else: The dynamic metabolic regulation of efferocytosisAlissa J. Trzeciak, Yating Wang, Justin S. A. Perry · 2021 · Cell Metabolism
- Macropinocytosis: Insights from immunology and cancerStow, Jennifer L., Hung, Yu, Wall, Adam A. · 2020 · Current Opinion in Cell Biology
- Cathepsin B modulates lysosomal biogenesis and host defense against Francisella novicida infectionXiaopeng Qi, Si Ming Man, R. K. Subbarao Malireddi, Rajendra Karki, Christopher R. Lupfer, Prajwal Gurung, Geoffrey A. M. Neale, Clifford S. Guy, Mohamed Lamkanfi, Thirumala‐Devi Kanneganti · 2016 · The Journal of Experimental Medicine
- Efficient Mitochondrial Glutamine Targeting Prevails Over Glioblastoma Metabolic PlasticityKristell Oizel, Cynthia Chauvin, Lisa Oliver, Catherine Gratas, Fanny Geraldo, Ulrich Jarry, Emmanuel Scotet, Marion Rabé, Marie‐Clotilde Alves‐Guerra, Raluca Teusan et al. · 2017 · Clinical Cancer Research
- The Canonical Wnt Pathway Drives Macropinocytosis in CancerGil Redelman‐Sidi, Anna Binyamin, Isabella Gaeta, Wilhelm Palm, Craig B. Thompson, Paul Bernard Romesser, Scott W. Lowe, Mukta Bagul, John G. Doench, David E. Root et al. · 2018 · Cancer Research
- Gold/alpha-lactalbumin nanoprobes for the imaging and treatment of breast cancerYang Jiang, Tai Wang, Lina Zhao, Vinagolu K. Rajasekhar, Suhasini Joshi, Chrysafis Andreou, Suchetan Pal, Hsiao‐Ting Hsu, Hanwen Zhang, Ivan Cohen et al. · 2020 · Nature Biomedical Engineering
- Lysosomal enzyme trafficking factor LYSET enables nutritional usage of extracellular proteinsCatarina Pechincha, Sven Groessl, Robert Kalis, Melanie de Almeida, Andrea Zanotti, Marten Wittmann, Martin Schneider, Rafael Paschoal de Campos, Sarah Rieser, Marlene Brandstetter et al. · 2022 · Science
- mTOR Inhibition Restores Amino Acid Balance in Cells Dependent on Catabolism of Extracellular ProteinMichel Nofal, Kevin Zhang, Seunghun Han, Joshua D. Rabinowitz · 2017 · Molecular Cell
- Macropinocytosis in Cancer: A Complex Signaling NetworkZhang, Yijuan, Commisso, Cosimo · 2019 · Trends in Cancer
- Modulation of dysregulated cancer metabolism by plant secondary metabolites: A mechanistic reviewSajad Fakhri, Seyed Zachariah Moradi, Mohammad Hosein Farzaei, Anupam Bishayee · 2020 · Seminars in Cancer Biology
- Transcription and Translation Inhibitors in Cancer TreatmentNihay Laham-Karam, Gaspar Pinto, Antti Poso, Piia Kokkonen · 2020 · Frontiers in Chemistry
- The Dual Role of Macropinocytosis in Cancers: Promoting Growth and Inducing Methuosis to Participate in Anticancer Therapies as TargetsShaojuan Song, Yanan Zhang, Tingting Ding, Ning Ji, Hang Zhao · 2021 · Frontiers in Oncology
- Pyrimidine Biosynthetic Enzyme CAD: Its Function, Regulation, and Diagnostic PotentialGuanya Li, Dunhui Li, Tao Wang, Shanping He · 2021 · International Journal of Molecular Sciences
- Metabolism within the tumor microenvironment and its implication on cancer progression: An ongoing therapeutic targetMa Carmen Ocaña, Beatriz Martı́nez-Poveda, Ana R. Quesada, Miguel Ángel Medina · 2018 · Medicinal Research Reviews
- An mTORC1-GRASP55 signaling axis controls unconventional secretion to reshape the extracellular proteome upon stressJulian Nüchel, Marina Tauber, Janica L. Nolte, Matthias Mörgelin, Clara Türk, Beate Eckes, Constantinos Demetriades, Markus Plomann · 2021 · Molecular Cell
- Ferroptosis inhibition by lysosome-dependent catabolism of extracellular proteinDavid A. Armenta, Nouf N. Laqtom, Grace A. Alchemy, Wentao Dong, Danielle Morrow, Carson D. Poltorack, David A. Nathanson, Monther Abu-Remaileh, Scott J. Dixon · 2022 · Cell chemical biology
- mTORC1 inhibition in cancer cells protects from glutaminolysis-mediated apoptosis during nutrient limitationVictor Hugo Villar, Tra-Ly Nguyen, Vanessa Delcroix, Silvia Terés, Marion Bouchecareilh, Bénédicte Salin, Clément Bodineau, Pierre Vacher, Muriel Priault, Pierre Soubeyran et al. · 2017 · Nature Communications
- Macropinocytosis Exploitation by Cancers and Cancer TherapeuticsKevin D. Ha, Scott M. Bidlingmaier, Bin Liu · 2016 · Frontiers in Physiology
- Lysosome as a Central Hub for Rewiring PH Homeostasis in TumorsRan Chen, Marja Jäättelä, Bin Liu · 2020 · Cancers
- Macropinocytosis: mechanisms and regulationGilbert Salloum, Anne R. Bresnick, Jonathan Backer · 2023 · Biochemical Journal
- Emerging mechanisms and promising approaches in pancreatic cancer metabolismHao Wu, Mengdi Fu, Mengwei Wu, Zhen Cao, Qiyao Zhang, Ziwen Liu · 2024 · Cell Death and Disease
- Nature and Nurture: What Determines Tumor Metabolic Phenotypes?Jared R. Mayers, Matthew G. Vander Heiden · 2017 · Cancer Research
- Macropinocytosis drives T cell growth by sustaining the activation of mTORC1John C. Charpentier, Di Chen, Philip Edward Lapinski, Jackson S. Turner, Irina Grigorova, Joel A. Swanson, Philip D. King · 2020 · Nature Communications
- Critical role for PI3-kinase in regulating the use of proteins as an amino acid sourceWilhelm Palm, Jingwen Araki, Bryan King, Raymond G. Dematteo, Craig B. Thompson · 2017 · Proceedings of the National Academy of Sciences
- mTOR signaling networks: mechanistic insights and translational frontiers in disease therapeuticsHanxiao Zhang, Xia Xiao, Zhenrui Pan, Svetlana Dokudovskaya · 2025 · Signal Transduction and Targeted Therapy
- Lysosomal protease deficiency or substrate overload induces an oxidative-stress mediated STAT3-dependent pathway of lysosomal homeostasisJonathan Martínez‐Fábregas, Alan R. Prescott, Sander I. van Kasteren, Deena M. Leslie Pedrioli, W.H. Irwin McLean, Anna Moles, Thomas Reinheckel, Valeria Poli, Colin K. W. Watts · 2018 · Nature Communications
- Mitochondrial Metabolism in PDAC: From Better Knowledge to New Targeting StrategiesGabriela Reyes‐Castellanos, Rawand Masoud, Alice Carrier · 2020 · Biomedicines
- Adaptive stimulation of macropinocytosis overcomes aspartate limitation in cancer cells under hypoxiaJavier García‐Bermúdez, Michael A. Badgley, Sheela Prasad, Lou Baudrier, Yuyang Liu, Konnor La, Mariluz Soula, Robert T. Williams, Norihiro Yamaguchi, Rosa F. Hwang et al. · 2022 · Nature Metabolism
- Dysregulated Amino Acid Sensing Drives Colorectal Cancer Growth and Metabolic Reprogramming Leading to ChemoresistanceSumeet A. Solanki, Katherine Sanchez, Varun Ponnusamy, Vasudha Kota, Hannah Noelle Bell, Chun‐Seok Cho, Allison Ho Kowalsky, Michael Green, Jun Hee Lee, Yatrik Madhukar Shah · 2022 · Gastroenterology
- Novel drugs that target the metabolic reprogramming in renal cell cancerJohannes Cornelis van der Mijn, David J. Panka, Andrew K. Geissler, Henk M.W. Verheul, James Walter Mier · 2016 · Cancer & Metabolism
- PI(3,4)P2 Signaling in Cancer and MetabolismLuca Gozzelino, Maria Chiara De Santis, Federico Gulluni, Emilio Hirsch, Miriam Martini · 2020 · Frontiers in Oncology
- Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesisJuan J Apiz Saab, Lindsey N. Dzierozynski, Patrick B. Jonker, Roya AminiTabrizi, Hardik Shah, Rosa Elena Menjivar, Andrew J. Scott, Zeribe C. Nwosu, Zhou Zhu, Riona N. Chen et al. · 2023 · eLife
- SNAT7 is the primary lysosomal glutamine exporter required for extracellular protein-dependent growth of cancer cellsQuentin Verdon, Marielle Boonen, Christopher Ribes, Michel Jadot, Bruno Gasnier, Corinne Sagné · 2017 · Proceedings of the National Academy of Sciences
- GSK3 Inhibits Macropinocytosis and Lysosomal Activity through the Wnt Destruction Complex MachineryL. Albrecht, Nydia Tejeda-Muñoz, Maggie H. Bui, Andrew C. Cicchetto, D. Di Biagio, Gabriele Colozza, Ernst W. Schmid, S. Piccolo, H. Christofk, E. De Robertis · 2020 · Cell Reports
- Targeting cancer metabolism by simultaneously disrupting parallel nutrient access pathwaysKim, Seong M., Roy, Saurabh G., Chen, Bin, Nguyen, Tiffany M., McMonigle, Ryan J., McCracken, Alison N., Zhang, Yanling, Kofuji, Satoshi, Hou, Jue, Selwan, Elizabeth et al. · 2016 · Journal of Clinical Investigation
- The GATOR–Rag GTPase pathway inhibits mTORC1 activation by lysosome-derived amino acidsG. Hesketh, Fotini Papazotos, J. Pawling, Dushyandi Rajendran, J. Knight, Sébastien Martinez, Mikko Taipale, D. Schramek, J. Dennis, A. Gingras · 2020 · Science
- Lymphangioleiomyomatosis: A Monogenic Model of MalignancyVera P. Krymskaya, Francis X. McCormack · 2017 · Annual Review of Medicine
- The Interplay of the Extracellular Matrix and Stromal Cells as a Drug Target in Stroma-Rich CancersKozlova, Nina, Grossman, Joseph E., Iwanicki, Marcin P., Muranen, Taru · 2020 · Trends in Pharmacological Sciences
- Reprogramming of Amino Acid Metabolism in Pancreatic Cancer: Recent Advances and Therapeutic StrategiesRuiyuan Xu, Jinshou Yang, Bo Ren, Huanyu Wang, Gang Yang, Yuan Chen, Lei You, Yupei Zhao · 2020 · Frontiers in Oncology
- Macrophages recycle phagocytosed bacteria to fuel immunometabolic responsesLesbats, Juliette, Brillac, Aurélia, Reisz, Julie A., Mukherjee, Parnika, Lhuissier, Charlène, Fernández-Monreal, Mónica, Dupuy, Jean-William, Sequeira, Angèle, Tioli, Gaia, De La Calle Arregui, Celia et al. · 2025 · Nature
- mTORC2 signaling drives the development and progression of pancreatic cancerDavid R. Driscoll, S. Karim, M. Sano, D. Gay, Wright Jacob, Jun Yu, Yusuke Mizukami, A. Gopinathan, D. Jodrell, T. R. Jeffry Evans et al. · 2016 · Cancer Research
- Eukaryotic Elongation Factor 2 Kinase (eEF2K) in CancerXuemin Wang, Jianling Xie, Christopher G. Proud · 2017 · Cancers
- Selective mTORC2 Inhibitor Therapeutically Blocks Breast Cancer Cell Growth and SurvivalThomas A. Werfel, Shan Wang, Meredith A. Jackson, Taylor E. Kavanaugh, Meghan M. Joly, Linus Lee, Donna J. Hicks, Violeta M. Sanchez, Paula I. González Ericsson, Kameron V. Kilchrist et al. · 2018 · Cancer Research
- The breadth of macropinocytosis researchJoel A. Swanson, Jason King · 2018 · Philosophical Transactions of the Royal Society B Biological Sciences
- RETRACTED ARTICLE: Long noncoding RNA LINC01234 promotes serine hydroxymethyltransferase 2 expression and proliferation by competitively binding miR-642a-5p in colon cancerChangwei Lin, Yi Zhang, Yifei Chen, Yang Bai, Yi Zhang · 2019 · Cell Death and Disease · Retracted
- Attacking the supply wagons to starve cancer cells to deathElizabeth M. Selwan, Brendan T. Finicle, Seong Min Kim, Aimee L. Edinger · 2016 · FEBS Letters
- Imaging Cancer Metabolism: Underlying Biology and Emerging StrategiesAustin R. Pantel, Daniel Ackerman, Seung‐Cheol Lee, David A. Mankoff, Terence P.F. Gade · 2018 · Journal of Nuclear Medicine
- Lysosomal enzyme trafficking: from molecular mechanisms to human diseases.T. Braulke, J. Carette, Wilhelm Palm · 2023 · Trends in Cell Biology
- TAT‐dextran–mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytesHideki Maeda, Daisuke Kami, Ryotaro Maeda, Yuki Murata, Jun‐ichiro Jo, Tomoya Kitani, Yasuhiko Tabata, Satoaki Matoba, Satoshi Gojo · 2020 · Journal of Cellular and Molecular Medicine
- Metabolic heterogeneity in cancer: An overview and therapeutic implicationsTong Yu, Wei‐Qiang Gao, Yanfeng Liu · 2020 · Biochimica et Biophysica Acta (BBA) - Reviews on Cancer
- The emerging role for metabolism in fueling neutrophilic inflammationTyler Morrison, Emily Watts, Pranvera Sadiku, Sarah R. Walmsley · 2022 · Immunological Reviews
- The extracellular matrix supports breast cancer cell growth under amino acid starvation by promoting tyrosine catabolismMona Nazemi, Bian Yanes, Montserrat Llanses, Heather J. Walker, Khoa Trong Pham, Mark O. Collins, Frédéric Bard, Elena Rainero · 2024 · PLoS Biology
- Exploiting cancer’s drinking problem: regulation and therapeutic potential of macropinocytosisJoseph Puccini, Michael A. Badgley, Dafna Bar‐Sagi · 2021 · Trends in cancer
- PLK1 (polo like kinase 1) inhibits MTOR complex 1 and promotes autophagyStefanie Ruf, Alexander Martin Heberle, Miriam Langelaar‐Makkinje, Sara Gelino, Deepti Wilkinson, Carolin Gerbeth, Jennifer Schwarz, Birgit Holzwarth, Bettina Warscheid, Chris Meisinger et al. · 2017 · Autophagy
- mTORC1 regulates a lysosome-dependent adaptive shift in intracellular lipid speciesAaron M. Hosios, Meghan E. Wilkinson, Molly C. McNamara, Krystle C. Kalafut, Margaret E. Torrence, John M. Asara, Brendan D. Manning · 2022 · Nature Metabolism
- Dietary pro-oxidant therapy by a vitamin K precursor targets PI 3-kinase VPS34 functionManojit Mosur Swamynathan, Shan Kuang, Kaitlin E. Watrud, Mary R. Doherty, Charlotte Gineste, Grinu Mathew, Grace Qun Gong, Hilary Cox, Eileen Cheng, David J. Reiss et al. · 2024 · Science
- PTRF/cavin-1 remodels phospholipid metabolism to promote tumor proliferation and suppress immune responses in glioblastoma by stabilizing cPLA2Kaikai Yi, Qi Zhan, Qixue Wang, Yanli Tan, Chuan Fang, Yunfei Wang, Junhu Zhou, Chao Yang, Yansheng Li, Chunsheng Kang · 2020 · Neuro-Oncology
- High glucose reduces megalin-mediated albumin endocytosis in renal proximal tubule cells through protein kinase B O-GlcNAcylationDiogo B. Peruchetti, Rodrigo Pacheco Silva-Aguiar, Gabriela Marques Siqueira, Wagner B. Dias, Celso Caruso‐Neves · 2018 · Journal of Biological Chemistry
- Exploiting the Therapeutic Interaction of WNT Pathway Activation and Asparaginase for Colorectal Cancer TherapyLaura Hinze, Roxane Labrosse, James Degar, Teng Han, Emma M. Schatoff, Sabine Schreek, Salmaan Karim, Connor McGuckin, Joshua R. Sacher, Florence F. Wagner et al. · 2020 · Cancer Discovery
- Unique metabolic features of pancreatic cancer stroma: relevance to the tumor compartment, prognosis, and invasive potentialErik S. Knudsen, Uthra Balaji, Elizaveta Freinkman, Peter A. McCue, Agnieszka Katarzyna Witkiewicz · 2016 · Oncotarget
- C9orf72 and smcr8 mutant mice reveal MTORC1 activation due to impaired lysosomal degradation and exocytosisQiang Shao, Mei Yang, Liang Chen, Li Ma, Wei Zhang, Zhiwen Jiang, Jun Luo, Jae‐Kyung Lee, Chengyu Liang, Jian‐Fu Chen · 2019 · Autophagy
- The therapeutic landscape of hepatocellular carcinomaSuchira Gallage, Maria Garcia Beccaria, Marta Szydlowska, Mohammad Rahbari, Raphael U. Mohr, Frank Tacke, Mathias F Heikenwälder · 2021 · Med
- Coordinate regulation of autophagy and the ubiquitin proteasome system by MTORJinghui Zhao, Alfred Lewis Goldberg · 2016 · Autophagy
- Yap/Taz promote the scavenging of extracellular nutrients through macropinocytosisBryan King, Jingwen Araki, Wilhelm Palm, Craig B. Thompson · 2020 · Genes & Development
- Targeting mTOR for Anti-Aging and Anti-Cancer TherapyWencheng Fu, Geng Wu · 2023 · Molecules
- Metabolic scavenging by cancer cells: when the going gets tough, the tough keep eatingEvdokia Michalopoulou, Vinay Bulusu, Jurre J. Kamphorst · 2016 · British Journal of Cancer
- Supply and demand: Cellular nutrient uptake and exchange in cancerVassilis Papalazarou, Oliver D.K. Maddocks · 2021 · Molecular Cell
- TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 SignalingStacy Y. Kasitinon, Uğur Eskiocak, Misty Martin, Divya Bezwada, Vishal Khivansara, Alpaslan Tasdogan, Zhiyu Zhao, Thomas P. Mathews, Arin B. Aurora, Sean J. Morrison · 2019 · Cell Reports
- Statin-induced GGPP depletion blocks macropinocytosis and starves cells with oncogenic defectsZhihua Jiao, Huaqing Cai, Long Yu, Orit Katarina Sirka, Veena Padmanaban, Andrew J. Ewald, Peter N. Devreotes · 2020 · Proceedings of the National Academy of Sciences
- Nutrient Sensing in CancerMargaret E. Torrence, Brendan D. Manning · 2017 · Annual Review of Cancer Biology
- An omic and multidimensional spatial atlas from serial biopsies of an evolving metastatic breast cancerBrett Johnson, Allison Creason, Jayne M. Stommel, Jamie M. Keck, Swapnil S Parmar, Courtney B. Betts, Aurora Blucher, Christopher T. Boniface, Elmar Bucher, Erik A. Burlingame et al. · 2022 · Cell Reports Medicine
- mTORC1 regulates cell survival under glucose starvation through 4EBP1/2-mediated translational reprogramming of fatty acid metabolismTal Levy, Kai Voeltzke, Laura A. Hruby, Khawla Alasad, Zuelal Bas, Marteinn Thor Snaebjornsson, Ran Marciano, Katerina Scharov, Mélanie Planque, Kim Vriens et al. · 2024 · Nature Communications
- The Role and Therapeutic Potential of Macropinocytosis in CancerZejing Qiu, Wen‐Cheng Liu, Qianru Zhu, Kun Ke, Qicong Zhu, Weiwei Jin, Shuxian Yu, Zuyi Yang, Lin Li, Xiaochen Sun et al. · 2022 · Frontiers in Pharmacology
- Acidosis orchestrates adaptations of energy metabolism in tumorsSven Groessl, Robert Kalis, Marteinn Thor Snaebjornsson, Leon Wambach, Jakob Haider, Florian Andersch, Almut Schulze, Wilhelm Palm, Johannes A. Zuber · 2025 · Science
- Getting Nervous: An Evolutionary Overhaul for CommunicationFrédérique Varoqueaux, Dirk Fasshauer · 2017 · Annual Review of Genetics
- Hypoxia drives murine neutrophil protein scavenging to maintain central carbon metabolismEmily Watts, Andrew J.M. Howden, Tyler Morrison, Pranvera Sadiku, Jens L. Hukelmann, Alex von Kriegsheim, Bart Ghesquière, Fiona A Murphy, Ananda S. Mirchandani, Duncan C. Humphries et al. · 2021 · Journal of Clinical Investigation
- Glutamine at focus: versatile roles in cancerHumberto De Vitto, Juan Alberto Pérez-Valencia, James A. Radosevich · 2015 · Tumor Biology
- Macropinosomes as units of signal transductionJoel A. Swanson, Sei Yoshida · 2018 · Philosophical Transactions of the Royal Society B Biological Sciences
- Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR InhibitionEvdokia Michalopoulou, Francesca Romana Auciello, Vinay Bulusu, David Strachan, Andrew D. Campbell, Jacqueline Tait-Mulder, Saadia A. Karim, Jennifer P. Morton, Owen James Sansom, Jurre J. Kamphorst · 2020 · Cell Reports
- MicroRNAs-103/107 coordinately regulate macropinocytosis and autophagyJong Kook Park, Han Peng, Julia Katsnelson, Wending Yang, Nihal Kaplan, Ying Dong, Joshua Zachary Rappoport, Congcong He, Robert M. Lavker · 2016 · The Journal of Cell Biology
- The pathogenesis of mesothelioma is driven by a dysregulated translatomeStefano Grosso, Alberto Marini, Katarína Gyurászová, Johan Vande Voorde, Aristeidis Sfakianos, Gavin D. Garland, Angela Rubio, Ryan Mordue, Tanya Chernova, Nobuhiro Morone et al. · 2021 · Nature Communications
- A novel mechanism of mTORC1-mediated serine/glycine metabolism in osteosarcoma developmentDawei Wang, Liwen Wu, Yang Cao, Lei Yang, Wei Liu, E Xiaoqiang, Guangrong Ji, Zhenggang Bi · 2016 · Cellular Signalling
- FcRn overexpression in human cancer drives albumin recycling and cell growth; a mechanistic basis for exploitation in targeted albumin-drug designsMaja Thim Larsen, Ole Aalund Mandrup, Karen Kræmmer Schelde, Yonglun Luo, Karina Dalsgaard Sørensen, Frederik Dagnæs‐Hansen, Jason Cameron, Magnus Stougaard, Torben Steiniche, Kenneth Alan Howard · 2020 · Journal of Controlled Release
- CXCL12-induced macropinocytosis modulates two distinct pathways to activate mTORC1 in macrophagesRegina Pacitto, Isabella Gaeta, Joel A. Swanson, Sei Yoshida · 2016 · Journal of Leukocyte Biology
- Harnessing the Co-vulnerabilities of Amino Acid-Restricted CancersGaurav Pathria, Ze’ev A. Ronai · 2021 · Cell Metabolism
- NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinomaTanya Schild, Melanie R. McReynolds, Christie Shea, Vivien Low, Bethany E. Schaffer, John M. Asara, Elena Piskounova, Noah Dephoure, Joshua D. Rabinowitz, Ana P. Gomes et al. · 2021 · Cell Reports
- Targeting fuel pocket of cancer cell metabolism: A focus on glutaminolysisShagun Sharma, Navneet Agnihotri, Sandeep Kumar · 2022 · Biochemical Pharmacology
- Amino Acid Transporters Are a Vital Focal Point in the Control of mTORC1 Signaling and CancerY. Cormerais, M. Vucetic, S. Parks, J. Pouysségur · 2020 · International Journal of Molecular Sciences
- Autophagic Mechanism in Anti-Cancer Immunity: Its Pros and Cons for Cancer TherapyYing-Ying Li, Lynn G. Feun, Angkana Thongkum, Chiao-Hui Tu, Shu-Mei Chen, Medhi Wangpaichitr, Chunjing Wu, Macus Tien Kuo, Niramol Savaraj · 2017 · International Journal of Molecular Sciences
- Mechanisms Governing Metabolic Heterogeneity in Breast Cancer and Other TumorsSayani Patra, Naveed Elahi, Aaron Armorer, Swathi Arunachalam, Joshua Omala, Iman Hamid, Anthony W. Ashton, David A. Joyce, Xuanmao Jiao, Richard G. Pestell · 2021 · Frontiers in Oncology
- Macropinocytosis and Cancer: From Tumor Stress to Signaling PathwaysGuillem Lambies, Cosimo Commisso · 2022 · Sub-cellular biochemistry/Subcellular biochemistry
- Macropinocytosis and autophagy crosstalk in nutrient scavengingOliver Florey, Michael Overholtzer · 2018 · Philosophical Transactions of the Royal Society B Biological Sciences
- Targeting metabolic plasticity in glioma stem cells in vitro and in vivo through specific inhibition of c-Src by TAT-Cx43266-283Sara G. Pelaz, Myriam Jaraíz-Rodríguez, Andrea Álvarez-Vázquez, Rocío Talaverón, Laura García-Vicente, Raquel Flores-Hernández, Marta Gómez de Cedrón, María Tabernero, Ana Ramı́rez de Molina, Concepción Lillo et al. · 2020 · EBioMedicine
- The biological role of metabolic reprogramming in pancreatic cancerTatsunori Suzuki, Motoyuki Otsuka, Takahiro Seimiya, Takuma Iwata, Takahiro Kishikawa, Kazuhiko Koike · 2020 · MedComm
- Resistance to targeted treatment of gastroenteropancreatic neuroendocrine tumorsMatthias Beyens, Timon Vandamme, Marc Peeters, Guy Van Camp, Ken Op de Beeck · 2018 · Endocrine Related Cancer
- Nutrient Control of mRNA TranslationXin Erica Shu, Robert V. Swanda, Shu‐Bing Qian · 2020 · Annual Review of Nutrition