Inhibiting DNA Methylation Causes an Interferon Response in Cancer via dsRNA Including Endogenous Retroviruses

Cited by (1,003)

Items 801–900 of 1,003

  1. Epigenetic Regulation of Cancer Immune Cells
    Diego M. Avella Patino, Vijay Radhakrishnan, Kanve Nagaraj Suvilesh, Yariswamy Manjunath, Guangfu Li, Eric T. Kimchi, Kevin F. Staveley-O’Carroll, Wesley C. Warren, Jussuf T. Kaifi, Jonathan B. Mitchem · 2021 · Seminars in Cancer Biology
  2. Integrating Immunotherapy with Chemotherapy: A New Approach to Drug Repurposing
    Hina Qayoom, Umar Mehraj, Shariqa Aisha, Shazia Sofi, Manzoor Ahmad Mir · 2021 · IntechOpen eBooks
  3. Ultraviolet light induces HERV expression to activate RIG‐I signalling pathway in keratinocytes
    Xiaoli Min, Meiling Zheng, Yaqin Yu, Jiali Wu, Qiqi Kuang, Zhi Qian Hu, Lianlian Ouyang, Shuang Lu, Ming Zhao · 2022 · Experimental Dermatology
  4. Neuron-specific chromosomal megadomain organization is adaptive to recent retrotransposon expansions
    Sandhya Chandrasekaran, Sergio Espeso‐Gil, Yong‐Hwee Eddie Loh, Behnam Javidfar, Bibi S. Kassim, Yueyan Zhu, Yuan Zhang, Yuhao Dong, Lucy K. Bicks, Haixin Li et al. · 2021 · Nature Communications
  5. Interplay between RNA interference and transposable elements in mammals
    Alexis Cornec, Enzo Z. Poirier · 2023 · Frontiers in Immunology
  6. CTLA4 DNA methylation is associated with CTLA-4 expression and predicts response to immunotherapy in head and neck squamous cell carcinoma
    Friederike Hoffmann, Alina Franzen, Luka de Vos, Lennert Wuest, Zsófi Kulcsár, Simon Fietz, Alexander Philippe Maas, Sarah Hollick, Marie Yatou Diop, Jennis Gabrielpillai et al. · 2023 · Clinical Epigenetics
  7. XAF1 promotes anti-RNA virus immune responses by regulating chromatin accessibility
    Ming Kuang, Yingchi Zhao, Haitao Yu, Siji Li, Tianyi Liu, Luoying Chen, Jingxuan Chen, Yujie Luo, Xuefei Guo, Xuemei Wei et al. · 2023 · Science Advances
  8. Hypermethylation of the VTRNA1-3 Promoter is Associated with Poor Outcome in Lower Risk Myelodysplastic Syndrome Patients
    Alexandra Søgaard Helbo, Marianne Bach Treppendahl, Derya Aslan, Konstantinos Dimopoulos, Cecilie Nandrup-Bus, Mette Holm, Mette Klarskov Andersen, Gangning Liang, Lasse S. Kristensen, Kirsten Grønbæk · 2015 · Genes
  9. Large-scale DNA methylation expression analysis across 12 solid cancers reveals hypermethylation in the calcium-signaling pathway
    Xiaoxiong Wang, Fu‐Hui Xiao, Qi-Gang Li, Jia Liu, Yonghan He, Qing‐Peng Kong · 2017 · Oncotarget
  10. Elevated HERV-K Expression in Soft Tissue Sarcoma Is Associated with Worsened Relapse-Free Survival
    Maria Giebler, Martin Sebastian Staege, Sindy Blauschmidt, Lea I. Ohm, Matthias Kraus, Peter Würl, Helge W. Taubert, Thomas Greither · 2018 · Frontiers in Microbiology
  11. Checkpoint inhibitors and acute myelogenous leukemia: promises and challenges
    Mansour Alfayez, Gautam M. Borthakur · 2018 · Expert Review of Hematology
  12. Contribution of Human Retroviruses to Disease Development—A Focus on the HIV– and HERV–Cancer Relationships and Treatment Strategies
    Ching‐Hsuan Liu, Nicole Grandi, Lalitha Palanivelu, Enzo Tramontano, Liang Lin · 2020 · Viruses
  13. A‐to‐I RNA editing by ADAR and its therapeutic applications: From viral infections to cancer immunotherapy
    Rohini Datta, Julia Z. Adamska, Amruta Bhate, Jin Billy Li · 2023 · Wiley Interdisciplinary Reviews - RNA
  14. Interplay between ATRX and IDH1 mutations governs innate immune responses in diffuse gliomas
    Seethalakshmi Hariharan, Benjamin T. Whitfield, Christopher J. Pirozzi, Matthew S. Waitkus, Michael C. Brown, Michelle L. Bowie, David Irvin, Kristen Roso, Rebecca Fuller, Janell Hostettler et al. · 2024 · Nature Communications
  15. G9a in Cancer: Mechanisms, Therapeutic Advancements, and Clinical Implications
    Yuchao Ni, Mingchen Shi, Liangliang Liu, Dong Lin, Hao Zeng, Christopher John Ong, Yuzhuo Z. Wang · 2024 · Cancers
  16. SMARCA4 regulates the NK-mediated killing of senescent cells
    Virinder Reen, Mariantonietta D’Ambrosio, Pia Pernille Søgaard, Katie Tyson, Bryony J. Leeke, Isabelle Clément, Isabel CA Dye, Joaquim Pombo, Adam Kuba, Yemin Lan et al. · 2025 · Science Advances
  17. DNMT1 inhibition reprograms T cells to NK-like cells with potent antitumor activity
    Yao Li, Jiongliang Wang, Linfu Zhou, Wenbin Gu, Le Qin, Dongdong Peng, Shanglin Li, Diwei Zheng, Qiting Wu, Youguo Long et al. · 2025 · Science Immunology
  18. OGT prevents DNA demethylation and suppresses the expression of transposable elements in heterochromatin by restraining TET activity genome-wide
    Hugo Sepúlveda, Xiang Li, Leo J. Arteaga-Vazquez, Isaac F. López-Moyado, Melina Brunelli, Lot Hernández-Espinosa, Xiaojing Yue, J. Carlos Angel, Caitlin Brown, Zhen Dong et al. · 2025 · Nature Structural & Molecular Biology
  19. Combined genetic and epigenetic interferences with interferon signaling expose prostate cancer cells to viral infection
    Oded Danziger, Ben Shai, Yosef Sabo, Eran Bacharach, Marcelo Ehrlich · 2016 · Oncotarget
  20. Epigenetic Drugs for Cancer and Precision Medicine
    Mukesh Verma, Vineet Kumar · 2017 · Elsevier eBooks
  21. Identification of prognostic signature in cancer based on DNA methylation interaction network
    Wei‐Lin Hu, Xionghui Zhou · 2017 · BMC Medical Genomics
  22. Blocking PD-1/PD-L1 in Genitourinary Malignancies
    Matthew C. Dallos, Charles G. Drake · 2018 · The Cancer Journal
  23. Fetal hemoglobin induction during decitabine treatment of elderly patients with high-risk myelodysplastic syndrome or acute myeloid leukemia: a potential dynamic biomarker of outcome
    Julia Stomper, Gabriele Ihorst, Stefan Suciu, Philipp N. Sander, Heiko Becker, Pierre Wijermans, Christoph Plass, Dieter Weichenhan, Emmanuel Bissé, Rainer Claus et al. · 2018 · Haematologica
  24. Friend and foe, HNRNPC takes on immunostimulatory RNAs in breast cancer cells
    Stephanie L. Sarbanes, Jérémie Le Pen, Charles M. Rice · 2018 · The EMBO Journal
  25. Lupus-associated endogenous retroviral LTR polymorphism and epigenetic imprinting promote HRES-1/RAB4 expression and mTOR activation
    Aparna Godavarthy, Ryan Kelly, John R. Jimah, Miguel Beckford, Tiffany N. Caza, David Fernández, Nick Huang, Manuel Duarte, Joshua Lewis, Hind J. Fadel et al. · 2019 · JCI Insight
  26. Epigenetic modulation combined with PD-1/PD-L1 blockade enhances immunotherapy based on MAGE-A11 antigen-specific CD8+T cells against esophageal carcinoma
    Yunyan Wu, Meixiang Sang, Fei Liu, Jiandong Zhang, Weijing Li, Zhenhua Li, Lina Gu, Yang Zheng, Juan Li, Baoen Shan · 2020 · Carcinogenesis
  27. TRIM28 Expression on Dendritic Cells Prevents Excessive T Cell Priming by Silencing Endogenous Retrovirus
    Shunsuke Chikuma, Soichiro Yamanaka, So Nakagawa, Mahoko Takahashi Ueda, Hodaka Hayabuchi, Yukiko Tokifuji, Masashi Kanayama, Tadashi Okamura, Hisashi Arase, Akihiko Yoshimura · 2021 · The Journal of Immunology
  28. Epigenetic Modifiers: Anti-Neoplastic Drugs With Immunomodulating Potential
    Ken Maes, Anna Mondino, Juan José Lasarte, Xabier Agirre, Karin Vanderkerken, Felipe Prósper, Karine Breckpot · 2021 · Frontiers in Immunology
  29. RNF135 Promoter Methylation Is Associated With Immune Infiltration and Prognosis in Hepatocellular Carcinoma
    Xiao Wang, Mengke Chen, Xiong Liang, Yu Bai, Judeng Zeng, Xiaoyi Xu, Hao Li, Jing Wang, Keyu Fan, Guijun Zhao · 2022 · Frontiers in Oncology
  30. FACT subunit SUPT16H associates with BRD4 and contributes to silencing of interferon signaling
    Dawei Zhou, Zhenyu Wu, Jun‐Gyu Park, Guillaume N. Fiches, Tai-Wei Li, Qin Ma, Huachao Huang, Ayan Biswas, Luis Martínez‐Sobrido, Netty G. Santoso et al. · 2022 · Nucleic Acids Research
  31. The Role of DNA Methylation and DNA Methyltransferases in Cancer
    Daniel J. Weisenberger, Ranjani Lakshminarasimhan, Gangning Liang · 2022 · Advances in experimental medicine and biology
  32. Fundamentals to therapeutics: Epigenetic modulation of CD8+ T Cell exhaustion in the tumor microenvironment
    Maja K. Blake, Patrick M. O’Connell, Yasser Ali Aldhamen · 2023 · Frontiers in Cell and Developmental Biology
  33. Expression profile of HERVs and inflammatory mediators detected in nasal mucosa as a predictive biomarker of COVID-19 severity
    Vita Petrone, Marialaura Fanelli, Martina Giudice, Nicola Toschi, Allegra Conti, Christian Maracchioni, Marco Iannetta, Claudia Resta, Chiara Cipriani, Martino Tony Miele et al. · 2023 · Frontiers in Microbiology
  34. H3K4 trimethylation regulates cancer immunity: a promising therapeutic target in combination with immunotherapy
    Chu Xiao, Tao T. Fan, Yujia Zheng, He Tian, Ziqin Deng, Jingjing Liu, Chunxiang Li, Jié He · 2023 · Journal for ImmunoTherapy of Cancer
  35. PD ‐1/ PD‐L1 blockade: Prospectives for immunotherapy in cancer and autoimmunity
    Ramin Hosseinzadeh, Fahimeh Feizisani, Navid Shomali, Walid Kamal Abdelbasset, Maryam Hemmatzadeh, Jamshid Gholizadeh Navashenaq, Farhad Jadidi‐Niaragh, Dmitry Olegovich Bokov, Morteza Janebifam, Hamed Mohammadi · 2021 · IUBMB Life
  36. A Three‐Pronged Epigenetic Approach to the Treatment of Hepatocellular Carcinoma
    Ryan A. Hlady, Keith D. Robertson · 2018 · Hepatology
  37. The Roles of H3K9me3 Writers, Readers, and Erasers in Cancer Immunotherapy
    Urszula Oleksiewicz, Monika Kuciak, Anna Maria Jaworska, Dominika Adamczak, Anna Bisok, Julia Mierzejewska, Justyna Sadowska, Patrycja Czerwińska, Andrzej Adam Mackiewicz · 2024 · International Journal of Molecular Sciences
  38. Cancer epigenetic therapy: recent advances, challenges, and emerging opportunities
    Rajita J. Vatapalli, Alex P. Rossi, Ho Man Chan, Jingwen Zhang · 2024 · Epigenomics
  39. Endogenous Retrovirus Transcript Levels Are Associated with Immunogenic Signatures in Multiple Metastatic Cancer Types
    James Thomas Topham, Emma Titmuss, Erin Pleasance, Laura M. Williamson, Joanna M. Karasinska, Luka Culibrk, Michael K.C. Lee, Shehara Ramyalini Mendis, Robert Edward Denroche, Gun-Ho Jang et al. · 2020 · Molecular Cancer Therapeutics
  40. Retroelement-derived RNA and its role in the brain
    Taylor A. Evans, Jennifer A. Erwin · 2020 · Seminars in Cell and Developmental Biology
  41. Combination of molecularly targeted therapies and immune checkpoint inhibitors in the new era of unresectable hepatocellular carcinoma treatment
    Ze-Long Liu, Jinghua Liu, Daniel Staiculescu, Jiang Chen · 2021 · Therapeutic Advances in Medical Oncology
  42. The role of human endogenous retroviruses in gliomas: from etiological perspectives and therapeutic implications
    Ashish Harish Shah, Mark R. Gilbert, Michael E. Ivan, Ricardo J. Komotar, John D. Heiss, Avindra Nath · 2021 · Neuro-Oncology
  43. Clinical efficacy and tumour microenvironment influence of decitabine plus R‐CHOP in patients with newly diagnosed diffuse large B‐Cell lymphoma: Phase 1/2 and biomarker study
    Mu‐Chen Zhang, Ying Fang, Pengpeng Xu, Lei Dong, Rong Shen, Yao‐Hui Huang, Di Fu, Zi‐Xun Yan, Shu Cheng, Xufeng Jiang et al. · 2021 · Clinical and Translational Medicine
  44. Epigenetics Regulates Antitumor Immunity in Melanoma
    Yuhan Chen, Xiuli Yi, Ningyue Sun, Weinan Guo, Chunying Li · 2022 · Frontiers in Immunology
  45. Satellite repeat RNA expression in epithelial ovarian cancer associates with a tumor-immunosuppressive phenotype
    Porter, Rebecca L., Sun, Siyu, Flores, Micayla N., Berzolla, Emily, You, Eunae, Phillips, Ildiko E., KC, Neelima, Desai, Niyati, Tai, Eric C., Szabolcs, Annamaria et al. · 2022 · Journal of Clinical Investigation
  46. Transcriptional Regulation of Endogenous Retroviruses and Their Misregulation in Human Diseases
    Qian Zhang, Juan Pan, Yu‐Sheng Cong, Jian Mao · 2022 · International Journal of Molecular Sciences
  47. Targeting RNA Exonuclease XRN1 Potentiates Efficacy of Cancer Immunotherapy
    Xue‐Bin Ran, Ling‐Wen Ding, Qiao-Yang Sun, Henry He Yang, Jonathan W. Said, Zhentang Lao, Vikas Madan, Pushkar Dakle, Jin-Fen Xiao, Xin-Yi Loh et al. · 2023 · Cancer Research
  48. Targeting nucleic acid sensors in tumor cells to reprogram biogenesis and RNA cargo of extracellular vesicles for T cell-mediated cancer immunotherapy
    Simon M Heidegger, Florian Stritzke, Sarah Dahl, Juliane Daßler‐Plenker, Laura Joachim, Dominik Buschmann, Kaiji Fan, Carolin M. Sauer, Nils Ludwig, Christof Winter et al. · 2023 · Cell Reports Medicine
  49. Human Endogenous Retrovirus K in the Crosstalk Between Cancer Cells Microenvironment and Plasticity: A New Perspective for Combination Therapy
    Emanuela Balestrieri, Ayele Argaw-Denboba, Alessandra Gambacurta, Chiara Cipriani, Roberto Bei, Annalucia Serafino, Paola Sinibaldi Vallebona, Claudia Matteucci · 2018 · Frontiers in Microbiology
  50. Priming a vascular-selective cytokine response permits CD8+ T-cell entry into tumors
    Dae Joong Kim, Swetha Anandh, Jamie L. Null, Piotr Przanowski, Sanchita Bhatnagar, Pankaj Kumar, Sarah E. Shelton, Erin E. Grundy, Katherine Bakshian Chiappinelli, Roger Dale Kamm et al. · 2023 · Nature Communications
  51. Epigenetic remodelling under hypoxia
    Roxane Verdikt, Bernard Thienpont · 2023 · Seminars in Cancer Biology
  52. Epigenetic therapy sensitizes anti–PD-1 refractory head and neck cancers to immunotherapy rechallenge
    Tingting Qin, Austin K. Mattox, Jean S. Campbell, Jong Chul Park, Kee-Young Shin, Shiting Li, Peter M. Sadow, William C. Faquin, Goran Micevic, Andrew J. Daniels et al. · 2025 · Journal of Clinical Investigation
  53. Depletion of ZBTB38 potentiates the effects of DNA demethylating agents in cancer cells via CDKN1C mRNA up-regulation
    Claire Marchal, Maud de Dieuleveult, Claude Saint‐Ruf, Nadège Guinot, Laure Ferry, Sara T. Olalla Saad, Mariana Lazarini, Pierre‐Antoine Defossez, Benoît Miotto · 2018 · Oncogenesis
  54. Fluctuations of epigenetic regulations in human gastric Adenocarcinoma: How does it affect?
    Ali Akbar Samadani, Seyedeh Elham Norollahi, Fariborz Mansour‐Ghanaei, Ali Rashidy‐Pour, Farahnaz Joukar, Ahmad Reza Bandegi · 2018 · Biomedicine & Pharmacotherapy
  55. Treatment with an immature dendritic cell-targeting vaccine supplemented with IFN-α and an inhibitor of DNA methylation markedly enhances survival in a murine melanoma model
    James T. Gordy, Kun Luo, Aakanksha R. Kapoor, Emily S. Kim, Samuel K. Ayeh, Petros C. Karakousis, Richard B. Markham · 2020 · Cancer Immunology Immunotherapy
  56. The DNA methyltransferase inhibitor zebularine exerts antitumor effects and reveals BATF2 as a poor prognostic marker for childhood medulloblastoma
    Augusto Faria Andrade, Kleiton Silva Borges, Veridiana Kiill Suazo, Lenisa Geron, Carolina Alves Pereira Corrêa, Angel Maurício Castro‐Gamero, Elton J. R. Vasconcelos, Ricardo Santos de Oliveira, Luciano Neder, José Andrés Yunes et al. · 2016 · Investigational New Drugs
  57. Skewed endosomal RNA responses from TLR7 to TLR3 in RNase T2-deficient macrophages
    Kaiwen Liu, Ryota Sato, Takuma Shibata, Ryosuke Hiranuma, Tatjana Reuter, Ryutaro Fukui, Yun Zhang, Takeshi Ichinohe, Manabu Ozawa, Nobuaki Yoshida et al. · 2021 · International Immunology
  58. Therapeutic Cancer Vaccination with Immunopeptidomics-Discovered Antigens Confers Protective Antitumor Efficacy
    Karita Peltonen, Sara Feola, Husen Muhammad Umer, Jacopo Chiaro, Georgios Mermelekas, Erkko O. Ylösmäki, Sari Anneli Pesonen, Rui Mamede Branca, Janne Lehtiö, Vincenzo Cerullo · 2021 · Cancers
  59. Hypomethylating Agent-Based Combination Therapies to Treat Post-Hematopoietic Stem Cell Transplant Relapse of Acute Myeloid Leukemia
    Giulia Ciotti, Giovanni Marconi, Giovanni Martinelli · 2022 · Frontiers in Oncology
  60. Cancer Genomics
    Marco Antonio Fonseca-Montaño, Sugela Blancas, Luis A. Herrera, Alfredo Hidalgo‐Miranda · 2022 · Archives of Medical Research
  61. Targeted therapy and immunotherapy: Diamonds in the rough in the treatment of epithelial ovarian cancer
    Xu Huang, Xiaoyu Li, Wulin Shan, Yao Chen, Qi Zhu, Bai-Rong Xia · 2023 · Frontiers in Pharmacology
  62. A Multi-Omics Overview of Colorectal Cancer to Address Mechanisms of Disease, Metastasis, Patient Disparities and Outcomes
    Guang Yang, Xi Yu, Daniel J. Weisenberger, Tao Lü, Gangning Liang · 2023 · Cancers
  63. SUMOylation inhibitor TAK-981 (subasumstat) synergizes with 5-azacytidine in preclinical models of acute myeloid leukemia
    Ludovic Gabellier, Marion de Toledo, Mehuli Chakraborty, Dana Akl, Rawan Hallal, Mays Aqrouq, Giovanni Buonocore, Clara Recasens-Zorzo, Guillaume Cartron, Abigaïl Delort et al. · 2023 · Haematologica
  64. SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer
    Xinyi Zhou, Yohei Sekino, Hongtao Li, Guanghou Fu, Yang Zhi, Shuqing Zhao, Hemant Gujar, Xiongbing Zu, Daniel J. Weisenberger, Inderbir Singh Gill et al. · 2023 · Cancer Research
  65. Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia
    Nandita Noronha, Chantal Durette, Maxime Cahuzac, Bianca E Silva, Justine Courtois, Juliette Humeau, Allan Sauvat, Marie‐Pierre Hardy, Krystel Vincent, Jean‐Philippe Laverdure et al. · 2024 · Leukemia
  66. Checkpoint Inhibition in Hodgkin Lymphoma - a Review
    Paul Jan Bröckelmann, Andreas Engert · 2017 · Oncology Research and Treatment
  67. Combined EZH2 Inhibition and IKAROS Degradation Leads to Enhanced Antitumor Activity in Diffuse Large B-cell Lymphoma
    Kit I. Tong, Sharon Yoon, Keren Isaev, Mehran Bakhtiari, Tracy Lackraj, Michael Y. He, Jesse Joynt, Anjali Silva, Maria C. Xu, Gilbert G. Privé et al. · 2021 · Clinical Cancer Research
  68. Endogenous retrovirus HERVH-derived lncRNA UCA1 controls human trophoblast development
    Xuhui Kong, Ruiqi Li, Manqi Chen, Rongyan Zheng, Jichang Wang, Chuanbo Sun, Yuliang Qu · 2024 · Proceedings of the National Academy of Sciences
  69. Getting the right combination to break the epigenetic code
    Seda Serra Tolu, Aaron D. Viny, Jennifer Effie Amengual, Barbara Pro, Susan Elaine Bates · 2024 · Nature Reviews Clinical Oncology
  70. Transposable elements as instructors of the immune system
    Lisa Schmidleithner, Philipp Stüve, Markus Feuerer · 2025 · Nature reviews. Immunology
  71. Clinical response to azacitidine in MDS is associated with distinct DNA methylation changes in HSPCs
    Julie A.I. Thoms, Feng Yan, Henry R. Hampton, Sarah Davidson, Swapna Mahurkar Joshi, Jesslyn Saw, Chowdhury Hasan Sarowar, Xin Ying Lim, Andrea C. Nunez, Purvi M. Kakadia et al. · 2025 · Nature Communications
  72. Transcriptional and post-transcriptional regulation of transposable elements and their roles in development and disease
    İbrahim Ilik, Yang Xu, ZZ Zhao Zhang, Tuğçe Aktaş · 2025 · Nature Reviews Molecular Cell Biology
  73. Novel Strategies for Peptide-Based Vaccines in Hematological Malignancies
    Uffe Klausen, Staffan Holmberg, Morten Orebo Holmström, Nicolai Grønne Dahlager Jørgensen, Jacob Handlos Grauslund, Inge Marie Svane, Mads Hald Andersen · 2018 · Frontiers in Immunology
  74. A Perspective on Therapeutic Pan-Resistance in Metastatic Cancer
    Dimitrios K. Korentzelos, Amanda M. Clark, Alan H. Wells · 2020 · International Journal of Molecular Sciences
  75. The anti-tumour activity of DNA methylation inhibitor 5-aza-2′-deoxycytidine is enhanced by the common analgesic paracetamol through induction of oxidative stress
    Hannah J. Gleneadie, Amy H. Baker, Nikolaos Batis, Jennifer Bryant, Yao Xing Jiang, Samuel J. H. Clokie, Hisham Mohamed Mehanna, Paloma García, Deena M.A. Gendoo, Sally Roberts et al. · 2021 · Cancer Letters
  76. Oral Azacitidine (CC-486) for the Treatment of Myeloid Malignancies
    Guillermo Garcia‐Manero, Hartmut Döhner, Andrew H. Wei, Ignazia La Torre, Barry Skikne, C.L. Beach, Valeria Santini · 2021 · Clinical Lymphoma Myeloma & Leukemia
  77. The TRRAP transcription cofactor represses interferon-stimulated genes in colorectal cancer cells
    Dylane Detilleux, Peggy Raynaud, Bérengère Pradet‐Balade, Dominique Helmlinger · 2022 · eLife
  78. Activating STING1-dependent immune signaling in TP53 mutant and wild-type acute myeloid leukemia
    Aksinija A. Kogan, Michael J. Topper, Anna J. Dellomo, Lora Stojanovic, Lena J. McLaughlin, T. Michael Creed, Christian L. Eberly, Tami J. Kingsbury, Maria R. Baer, Michael D. Kessler et al. · 2022 · Proceedings of the National Academy of Sciences
  79. The antileukemic activity of decitabine upon PML/RARA-negative AML blasts is supported by all-trans retinoic acid: in vitro and in vivo evidence for cooperation
    Ruth Meier, Gabriele Greve, Dennis Zimmer, Helena Bresser, Bettina Berberich, Ralitsa Langova, Julia Stomper, Anne Rubarth, Lars Feuerbach, Daniel B. Lipka et al. · 2022 · Blood Cancer Journal
  80. The Role of Epigenetics in the Development and Progression of Multiple Myeloma
    Ismail, Nor Hayati, Mussa, Ali, Zakaria, Nur Atikah, Al-Khreisat, Mutaz Jamal, Zahidin, Muhamad Aidil, Ramli, Noor Nabila, Mohammad, Siti Nur Nabeela A’ifah, Hassan, Rosline, Mohd Noor, Noor Haslina, Iberahim, Salfarina et al. · 2022 · Biomedicines
  81. TERT promoter mutations and methylation for telomerase activation in urothelial carcinomas: New mechanistic insights and clinical significance
    Tiantian Liu, Shihong Li, Chuanyou Xia, Dawei Xu · 2023 · Frontiers in Immunology
  82. Epigenetic Regulators of DNA Cytosine Modification: Promising Targets for Cancer Therapy
    Inkyung Jung, Jungeun An, Myunggon Ko · 2023 · Biomedicines
  83. Migrasomes trigger innate immune activation and mediate transmission of senescence signals across human cells
    Liu, Xiaoqian, Jiao, Haifeng, Zhang, Baohu, Zhang, Sheng, Yan, Kaowen, Qu, Jing, Zhang, Weiqi, Yu, Li, Liu, Guang-Hui · 2023 · Life Medicine
  84. Senescent human hematopoietic progenitors show elevated expression of transposable elements and inflammatory genes
    Stephen Capone, Kwasi M. Connor, Anthony Colombo, Xin Li, Timothy J. Triche, Giridharan Ramsingh · 2018 · Experimental Hematology
  85. Can we predict responsiveness to hypomethylating agents in AML?
    Julia Stomper, Michael Lübbert · 2019 · Seminars in Hematology
  86. Epigenetics of cutaneous T-cell lymphoma: biomarkers and therapeutic potentials
    Pan Lai, Yang Wang · 2021 · Cancer Biology and Medicine
  87. Epigenetic downregulation of STAT6 increases HIF-1α expression via mTOR/S6K/S6, leading to enhanced hypoxic viability of glioma cells
    Soo Jung Park, Hyunmi Kim, Se Hyuk Kim, Eun-hye Joe, Ilo Jou · 2019 · Acta Neuropathologica Communications
  88. Low-dose DNA demethylating therapy induces reprogramming of diverse cancer-related pathways at the single-cell level
    Hideyuki Takeshima, Yukie Yoda, Mika Wakabayashi, Naoko Hattori, Satoshi Yamashita, Toshikazu Ushijima · 2020 · Clinical Epigenetics
  89. High-Throughput-Methyl-Reading (HTMR) assay: a solution based on nucleotide methyl-binding proteins enables large-scale screening for DNA/RNA methyltransferases and demethylases
    Sen-Hao Xiao, Siqi Guo, Jie Han, Yanli Sun, Mingchen Wang, Yantao Chen, Xueyu Fang, Feng Yang, Yajuan Mu, Liang Zhang et al. · 2021 · Nucleic Acids Research
  90. Introns encode dsRNAs undetected by RIG-I/MDA5/interferons and sensed via RNase L
    Alisha Chitrakar, Kristina Solorio-Kirpichyan, Eliza Prangley, Sneha P. Rath, Jin Du, Alexei V. Korennykh · 2021 · Proceedings of the National Academy of Sciences
  91. MER4 endogenous retrovirus correlated with better efficacy of anti-PD1/PD-L1 therapy in non-small cell lung cancer
    Julie Lecuelle, Laure Favier, Cléa Fraisse, Aurélie Lagrange, Courèche Kaderbhaï, Romain Boidot, Sandy Chevrier, Philippe Joubert, Bertrand Routy, Caroline Truntzer et al. · 2022 · Journal for ImmunoTherapy of Cancer
  92. Decitabine Treatment Induces a Viral Mimicry Response in Cervical Cancer Cells and Further Sensitizes Cells to Chemotherapy
    Alexia Alexandraki, Katerina Strati · 2022 · International Journal of Molecular Sciences
  93. circCsnk1g3- and circAnkib1-regulated interferon responses in sarcoma promote tumorigenesis by shaping the immune microenvironment
    Roberta Piras, Emily Y. Ko, Connor Barrett, Marco Claudio De Simone, Xianzhi Lin, Marina T. Broz, Fernando Henrique Galvão Tessaro, Mireia Castillo-Martín, Carlos Cordon‐Cardo, Helen S. Goodridge et al. · 2022 · Nature Communications
  94. Multi-Omics Immune Interaction Networks in Lung Cancer Tumorigenesis, Proliferation, and Survival
    Qing Ye, Justin Hickey, Kathleen Summers, Brianne Falatovich, Marieta Gencheva, Timothy D. Eubank, Alexey V. Ivanov, Nancy Lan Guo · 2022 · International Journal of Molecular Sciences
  95. Transcriptional and Epigenetic Regulation of Context-Dependent Plasticity in T-Helper Lineages
    Meyer J. Friedman, Haram Lee, June‐Yong Lee, Soohwan Oh · 2023 · Immune Network
  96. Bifunctional HDAC and DNMT inhibitor induces viral mimicry activates the innate immune response in triple-negative breast cancer
    Weiwen Fan, Wenkai Li, Lulu Li, Meirong Qin, Chengzhou Mao, Zigao Yuan, Ping Wang, Bizhu Chu, Yuyang Jiang · 2024 · European Journal of Pharmaceutical Sciences
  97. When DNA damage responses meet tumor immunity: From mechanism to therapeutic opportunity
    Dong Pan, Qi Wang, Aihua Shen, Zhihao Qi, Chunfu Zheng, Burong Hu · 2024 · International Journal of Cancer
  98. Transposable element dysregulation in systemic lupus erythematosus and regulation by histone conformation and Hsp90
    Kelly Dietzmann-Maurer, Shi Lihua, Zhe Zhang, Song Li, Paucar Yoselin, Petri Michelle, E Sullivan Kathleen · 2018 · Clinical Immunology
  99. Which are the most promising targets for minimal residual disease-directed therapy in acute myeloid leukemia prior to allogeneic stem cell transplant?
    Brian J. Ball, Eytan M. Stein · 2019 · Haematologica
  100. Fra-2/AP-1 regulates melanoma cell metastasis by downregulating Fam212b
    Guangliang Chen, Rui Li, Xiaoxiang Chen, Juan Wang, Shan Cao, Rui Song, Ming-Chun Zhao, Liming Li, Nicole Hannemann, Georg Andreas Schett et al. · 2020 · Cell Death and Differentiation