The DOI matches its Crossref record; 49 of the 49 references it cites were found in a registry or an index.
Mitochondrial DNA Variation in Human Radiation and Disease
Open accessAbstract
Environmental adaptation, predisposition to common diseases, and, potentially, speciation may all be linked through the adaptive potential of mitochondrial DNA (mtDNA) alterations of bioenergetics. This Perspective synthesizes evidence that human mtDNA variants may be adaptive or deleterious depending on environmental context and proposes that the accrual of mtDNA variation could contribute to animal speciation via adaptation to marginal environments.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Wallace, D. C. (2005) · Annual Review of Genetics · doi:10.1146/annurev.genet.39.110304.095751 · Cited by 3,185
Self-citationMitochondrial DNA and human evolution
Cann, R. L., Stoneking, M., & Wilson, A. C. (1987) · Nature · doi:10.1038/325031a0 · Cited by 3,100
Mitochondrial DNA mutation associated with Leber’s hereditary optic neuropathy
Wallace, D. C., Singh, G., Lott, M. T., Hodge, J. A., Schurr, T. G., Lezza, A. M. S., Elsas, L. J., & Nikoskelainen, E. K. (1988) · Science · doi:10.1126/science.3201231 · Cited by 2,440
Self-citationGenome-wide detection and characterization of positive selection in human populations
The International HapMap Consortium, Sabeti, P. C., Varilly, P., Fry, B., Lohmueller, J., Hostetter, E., Cotsapas, C., Xie, X., Byrne, E. H., McCarroll, S. A., et al. (2007) · Nature · doi:10.1038/nature06250 · Cited by 2,131
Updated comprehensive phylogenetic tree of global human mitochondrial DNA variation
van Oven, M., & Kayser, M. (2009) · Human Mutation · doi:10.1002/humu.20921 · Cited by 1,810
Altitude adaptation in Tibetans caused by introgression of Denisovan-like DNA
Huerta-Sánchez, E., Jin, X., Asan, Bianba, Z., Peter, B. M., Vinckenbosch, N., Liang, Y., Yi, X., He, M., Somel, M., et al. (2014) · Nature · doi:10.1038/nature13408 · Cited by 1,208
Natural selection shaped regional mtDNA variation in humans
Mishmar, D., Ruiz-Pesini, E., Golik, P., Macaulay, V., Clark, A. G., Hosseini, S., Brandon, M., Easley, K., Chen, E., Brown, M. D., et al. (2003) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0136972100 · Cited by 1,038
Self-citationMitochondrial mutations in cancer
Brandon, M., Baldi, P., & Wallace, D. C. (2006) · Oncogene · doi:10.1038/sj.onc.1209607 · Cited by 818
Self-citationEffects of Purifying and Adaptive Selection on Regional Variation in Human mtDNA
Ruiz-Pesini, E., Mishmar, D., Brandon, M., Procaccio, V., & Wallace, D. C. (2004) · Science · doi:10.1126/science.1088434 · Cited by 806
Self-citationTrounce, I. A., Kim, Y. L., Jun, A. S., & Wallace, D. C. (1996) · Methods in Enzymology · doi:10.1016/s0076-6879(96)64044-0 · Cited by 746
Self-citation
Cited by
Mitochondrial DNA in innate immune responses and inflammatory pathology
West, A. P., & Shadel, G. S. (2017) · Nature Reviews Immunology · doi:10.1038/nri.2017.21 · Cited by 1,115
Nuclear DNA damage signalling to mitochondria in ageing
Fang, E. F., Scheibye-Knudsen, M., Chua, K. F., Mattson, M. P., Croteau, D. L., & Bohr, V. A. (2016) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2016.14 · Cited by 387
Mitochondrial and nuclear DNA matching shapes metabolism and healthy ageing
Latorre-Pellicer, A., Moreno-Loshuertos, R., Lechuga-Vieco, A. V., Sánchez-Cabo, F., Torroja, C., Acín-Pérez, R., Calvo, E., Aix, E., González-Guerra, A., Logan, A., et al. (2016) · Nature · doi:10.1038/nature18618 · Cited by 377
The architecture of the mammalian respirasome
Gu, J., Wu, M., Guo, R., Yan, K., Lei, J., Gao, N., & Yang, M. (2016) · Nature · doi:10.1038/nature19359 · Cited by 367
Mitochondria: It is all about energy
Casanova, A., Wevers, A., Navarro-Ledesma, S., & Pruimboom, L. (2023) · Frontiers in Physiology · doi:10.3389/fphys.2023.1114231 · Cited by 303
Metadata
- Authors
- Wallace, D. C.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2015-09
- Volume
- 163
- Issue
- 1
- Pages
- 33-38
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2138532379
- Cited by
- 256
- References
- 49
- FWCI
- 8.23
- Type
- journal article
- Language
- en
- Open access
- bronze
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Mitochondrial DNA Variation in Human Radiation and Disease. https://app.cochat.ai/papers/10.1016/j.cell.2015.08.067
- The paper
- Wallace, D. C. (2015). Mitochondrial DNA Variation in Human Radiation and Disease. Cell. https://doi.org/10.1016/j.cell.2015.08.067
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
