Acquired Tissue-Specific Promoter Bivalency Is a Basis for PRC2 Necessity in Adult Cells
Jadhav, Unmesh, Nalapareddy, Kodandaramireddy, Saxena, Madhurima, O’Neill, Nicholas K., Pinello, Luca, Yuan, Guo-Cheng, Orkin, Stuart H., Shivdasani, Ramesh A.·2016·Cell
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- H3K27me3 Demethylases Maintain the Transcriptional and Epigenomic Landscape of the Intestinal EpitheliumHannah M. Kolev, Avital Swisa, Elisabetta Manduchi, Yemin Lan, Rachel R. Stine, Giuseppe Testa, Klaus H. Kaestner · 2022 · Cellular and Molecular Gastroenterology and Hepatology
- Life and death rest on a bivalent chromatin stateXueping Yang · 2016 · Nature Neuroscience
- Most of transcriptional alterations in glioma result from DNA-methylation independent mechanismsFranck Court, Elisa Le Boiteux, Anne Fogli, Mélanie Müller-Barthélémy, Catherine Vaurs‐Barrière, Emmanuel Chautard, Bruno Pereira, J. Biau, Jean‐Louis Kémény, Toufic Khalil et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
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- Liver-derived Indian hedgehog (Ihh) couples fast-feed transition to thermogenic and metabolic homeostasisRaffaele Teperino, Marketa Adamová, Shefa’ Muneer Aljabali, Shruta Sandesh Pai, Raffaele Gerlini, Irene Paez-Perez, Madlen Matz‐Soja, Steffen Heyne, Adelheid M. Lempradl, Maria Felicia Basilicata et al. · 2026 · Molecular Metabolism
- Transcriptional and Epigenetic Mechanisms Controlling Intestinal Cell FateFulvio Chiacchiera · 2019 · Elsevier eBooks
- EZH1 as a key mediator of exercise-induced H3K27me3 and H3K4me3 in mouse skeletal muscleJunya Shimizu, Naoki Horii, Yusuke Ono, Fuminori Kawano · 2024 · Advanced Exercise and Health Science
- DNA glycosylases Ogg1 and Mutyh influence gene expression of PRC2 targets associated with cognitionAndreas Abentung, Teri Sakshaug, Rabina Dumaru, Nina‐Beate Liabakk, Mingyi Yang, Junbai Wang, Magnar Bjørås, Katja Scheffler · 2025 · Cellular and Molecular Life Sciences
- Epigenomic signatures on paralogous genes reveal underappreciated universality of active histone codes adopted across animalsKuei-Yuan Lan, Ben‐Yang Liao · 2021 · Computational and Structural Biotechnology Journal
- EED Maintains the Small Cell Lung Cancer Neuroendocrine Phenotype and Drives Lung Cancer Histological TransformationYixiang Li, Yasmin Nabil Laimon, Hyeonseo Cho, Marina Vivero, Gabriel Roberti De Oliveira, Andrew Delcea, Varunika Savla, Yuting Chen, Yavuz T. Durmaz, Xintao Qiu et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- H2AK119ub1-MLL2 counteraction underlies heritable H3K27me3 formation in oocytesHailiang Mei, Chisayo Kozuka, Mami Kumon, Haruhiko Koseki, Azusa Inoue · 2026 · Molecular Cell
- T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type 1 cellsJosep Garnica, Patricia Solé, Jun Yamanouchi, Joel Moro, Debajyoti Mondal, César Fandos, Pau Serra, Pere Santamaría · 2024 · eLife
- A novel antiviral lncRNA EDAL shields a T309 O-GlcNAcylation site to promote EZH2 degradationBao-Kun Sui, Dong Chen, Wei Liu, Qiong Wu, Bin Tian, Jing Hou, Ying-Ying Li, Shiyong Liu, Juan Xie, Hao Jiang et al. · 2019 · bioRxiv
- DNA methylation-dependent and -independent binding of CDX2 directs activation of distinct developmental and homeostatic genesAlireza Lorzadeh, George Ye, Sweta Sharma, Unmesh Jadhav · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- DNA glycosylases Ogg1 and Mutyh mediate gene expression of PRC2 target genes important for neuronal processes underlying memory formationAndreas Abentung, Teri Sakshaug, Rabina Dumaru, N. Liabakk, Ming-Yi Yang, Junbai Wang, Magnar Bjørås, K. Scheffler · 2024 · bioRxiv
- EZH2-TTP-mTORC1 Axis Drives Phenotypic Plasticity and Therapeutic Vulnerability in Lethal Prostate CancerBeatriz German, Katherine L. Morel, Teia Noel, Nadia Boufaied, Deborah L. Burkhart, Sujun Chen, Felipe Segato Dezem, Xintao Qiu, Henry W. Long, Stefan DiFazio et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Mitotic bookmarking by Prox1 preserves mammalian neuronal lineage identity memory via promoting timely H3K27me3 restorationChouin Wong, Jiayi Liu, Haoran Yang, Haotian Li, Xiaoqi Luo, Tingyi Li, Zili Chen, Jingyi Chu, Yuying Shen, Shuai Long et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Natural Selection, Crypt Fitness, and Pol III Dependency in the IntestineUnmesh Jadhav, Ramesh A. Shivdasani · 2016 · Cellular and Molecular Gastroenterology and Hepatology
- An annotated list of bivalent chromatin regions in human ES cells: a new tool for cancer epigenetic researchFranck Court, Philippe Arnaúd · 2018 · arXiv (Cornell University)
- Epigenetic Control of Mesenchymal-Epithelial Interactions Directs Gastrointestinal DevelopmentRyan Smith · 2018 · TSpace (University of Toronto)
- Epigenetic fun(ction) in the sunMegan K. He, Brian C. Raftrey, Ya‐Chieh Hsu · 2021 · Developmental Cell
- Faculty Opinions recommendation of The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.Blaine Bartholomew · 2019 · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature
- KDM6A/B Demethylases in Gut HomeostasisNatalia V. Soshnikova · 2023 · Cellular and Molecular Gastroenterology and Hepatology
- eLife Assessment: T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cellsMasato Kubo · 2024 · eLife
- Reviewer #1 (Public Review): T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells2024 · eLife
- T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cellsJosep Garnica, Patricia Solé, Jun Yamanouchi, Joel Moro, Debajyoti Mondal, César Fandos, Pau Serra, Pere Santamaría · 2024 · eLife
- Author response: T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cellsJosep Garnica, Patricia Solé, Jun Yamanouchi, Joel Moro, Debajyoti Mondal, César Fandos, Pau Serra, Pere Santamaría · 2024 · eLife
- Reviewer #2 (Public Review): T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cells2024 · eLife
- T-follicular helper cells are epigenetically poised to transdifferentiate into T-regulatory type-1 cellsJosep Garnica, Patricia Solé, Jun Yamanouchi, Joel Moro, Debajyoti Mondal, César Fandos, Pau Serra, Pere Santamaría · 2024 · eLife
- Conserved Master Regulators Orchestrate Cellular Reprogramming-Induced RejuvenationAli Doğa Yücel, Harlan P. Stevens, Alexander Tyshkovskiy, Vadim N. Gladyshev · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Epigenetic Gatekeeping of Wnt-Responsive Enhancers Restricts Intestinal Stem Cell TransformationAlireza Lorzadeh, Sweta Sharma, George Ye, Sabrina Rabaya, Yun Jee Kang, Ramesh A. Shivdasani, Unmesh Jadhav · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Vers l'identification des facteurs impliqués dans la régulation concertée des gènes soumis à empreinte dans le cerveauJil Cercy · 2019 · theses.fr (ABES)
- Altération du contrôle de H3K27me3 et dérégulation transcriptionnnelle dans les gliomes : études des clusters HOXElisa Le Boiteux · 2019 · theses.fr (ABES)
- Etude des mécanismes impliqués dans le contrôle du destin des cellules souches intestinales et développement d'un modèle 3D d'épithélium intestinalJustine Creff · 2019 · theses.fr (ABES)
- CoCUT&Tag maps linked chromatin states at single-molecule, single-cell resolutionWenjie Sun, Emma Baird, Harry J Ashbaugh, Alexandria P. Eiken, Derek H. Janssens · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
- Polycomb scaffolding subunit EED supports the SCLC neuroendocrine identity and EGFR-mutant LUAD-to-SCLC transformationYixiang Li, Yasmin Nabil Laimon, Hyeonseo Cho, Marina Vivero, Gabriel Roberti De Oliveira, Maxwell D. Seager, Andrew Delcea, Varunika Savla, Yuting Chen, Yavuz T. Durmaz et al. · 2025 · Journal of Clinical Investigation
- Written in development and lost in ageing: the grammar of cellular identityAli Doğa Yücel, Adrian Molière, Vadim N. Gladyshev · 2026 · Nature
- EZH2-dependent phenotypic plasticity reveals TTP-associated and mTORC1 therapeutic vulnerabilities in lethal prostate cancerBeatriz German, Katherine L. Morel, Teia Noel, Nadia Boufaied, Deborah L. Burkhart, Sujun Chen, Felipe Dezem, Xintao Qiu, Henry W. Long, Kun-Lin Ho et al. · 2026 · Cell Reports Medicine