Molecular diversity of midbrain development in mouse, human, and stem cells

La Manno, Gioele, Gyllborg, Daniel, Codeluppi, Simone, Nishimura, Kaneyasu, Salto, Carmen, Zeisel, Amit, Borm, Lars E., Stott, Simon R.W. +7 more·2016·Cell

Cited by (842)

Items 501–600 of 842

  1. Single-Cell RNA Sequencing of Oligodendrocyte Lineage Cells from the Mouse Central Nervous System
    Sueli Marques, David van Bruggen, Gonçalo Castelo‐Branco · 2019 · Methods in molecular biology
  2. Divide and conquer: A perspective on biochips for single-cell and rare-molecule analysis by next-generation sequencing
    Amos Chungwon Lee, Yong‐Ju Lee, Daewon Lee, Sunghoon Kwon · 2019 · APL Bioengineering
  3. Gene Selection and Classification of scRNA‐seq Data Combining Information Gain Ratio and Genetic Algorithm with Dynamic Crossover
    Junhong Feng, Xishuan Niu, Jie Zhang, Jian‐Hong Wang · 2022 · Wireless Communications and Mobile Computing
  4. Molecular Programming of Mesodiencephalic Dopaminergic Neuronal Subsets
    Marten P. Smidt · 2017 · Frontiers in Neuroanatomy
  5. Nanomaterial-involved neural stem cell research: Disease treatment, cell labeling, and growth regulation
    Xiangyu Liu, Chengbin Zhou, Chao Fang · 2018 · Biomedicine & Pharmacotherapy
  6. Transcriptional Profiling of Xenogeneic Transplants: Examining Human Pluripotent Stem Cell-Derived Grafts in the Rodent Brain
    Christopher R. Bye, Vanessa Penna, Isabelle R. de Luzy, Carlos W. Gantner, Cameron J. Hunt, Lachlan H. Thompson, Clare L. Parish · 2019 · Stem Cell Reports
  7. Molecular diversity and migration of GABAergic neurons in the developing ventral midbrain
    Özge Düdükcü, Divya D. A. Raj, Lieke L. van de Haar, Laurens M. Grossouw, Louisa E. Linders, Oxana Garritsen, Youri Adolfs, Nicky C.H. van Kronenburg, Mark H. Broekhoven, Troy H W Kapteijns et al. · 2024 · iScience
  8. Alcohol use disorder and body mass index show genetic pleiotropy and shared neural associations
    Samantha G. Malone, Christal N. Davis, Zachary Piserchia, Michael R. Setzer, Sylvanus Toikumo, Hang Zhou, Emma L. Winterlind, Joel E. Gelernter, Amy C. Justice, Lorenzo Leggio et al. · 2025 · Nature Human Behaviour
  9. BrainSTEM: A single-cell multiresolution fetal brain atlas reveals transcriptomic fidelity of human midbrain cultures
    Hilary S. Y. Toh, Lisheng Xu, Carissa Chen, Pengyi Yang, Alfred Xuyang Sun, John F. Ouyang · 2025 · Science Advances
  10. The need for a standard for informed consent for collection of human fetal material
    Roger A. Barker, Gerard J. Boer, Elena F. Cattaneo, R. Alta Charo, Susana M. Chuva de Sousa Lopes, Yali Cong, Misao Fujita, Steven A. Goldman, Göran Hermerén, Insoo Hyun et al. · 2022 · Stem Cell Reports
  11. Genome-wide association study of cerebellar white matter microstructure and genetic overlap with common brain disorders
    Bang‐Sheng Wu, Yi‐Jun Ge, Wei Zhang, Shi-Dong Chen, Shitong Xiang, Ya-Ru Zhang, Ya‐Nan Ou, Yuchao Jiang, Lan Tan, Wei Cheng et al. · 2023 · NeuroImage
  12. Insights into Neurodegeneration in Parkinson's Disease from Single‐Cell and Spatial Genomics
    Tushar Kamath, Evan Z. Macosko · 2023 · Movement Disorders
  13. Quantitative Proteomics for the Development and Manufacturing of Human-Induced Pluripotent Stem Cell-Derived Neural Stem Cells Using Data-Independent Acquisition Mass Spectrometry
    Takaya Urasawa, Takumi Koizumi, Kazumasa Kimura, Yuki Ohta, Nana Kawasaki · 2023 · Journal of Proteome Research
  14. Multiomics analysis identifies novel facilitators of human dopaminergic neuron differentiation
    Borja Gomez Ramos, Jochen Ohnmacht, Nikola de Lange, Elena Valceschini, Aurélien Ginolhac, Marie Catillon, Daniele Ferrante, Aleksandar Raković, Rashi Halder, François Massart et al. · 2023 · EMBO Reports
  15. Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
    Zachary A. Gaertner, Cameron Oram, Amanda K. Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel A. Dombeck, Loukia Parisiadou, Jean-Francois Poulin, Rajeshwar B. Awatramani · 2025 · eLife
  16. State of the Art in Sub-Phenotyping Midbrain Dopamine Neurons
    Valentina Basso, Máté Daniel Döbrössy, Lachlan H. Thompson, Deniz Kirik, Heidi R. Fuller, Monte A. Gates · 2024 · Biology
  17. Modeling Spatial Correlation of Transcripts with Application to Developing Pancreas
    Ruishan Liu, Marco Mignardi, Robert C. Jones, M. Enge, Seung K. Kim, S. Quake, James Zou · 2018 · Scientific Reports
  18. Heterogeneity of Stem Cells in the Hippocampus
    Mehmet Tosun, Fatih Semerci, Mirjana Maletić‐Savatić · 2019 · Advances in experimental medicine and biology
  19. Characterization of SALL2 Gene Isoforms and Targets Across Cell Types Reveals Highly Conserved Networks
    C. Farkas, A. Quiroz, C. Álvarez, V. Hermosilla, C. Aylwin, A. Lomniczi, Ariel F. Castro, Matías I. Hepp, R. Pincheira · 2021 · Frontiers in Genetics
  20. Modeling SARS-CoV-2 infection in individuals with opioid use disorder with brain organoids
    Moshe J. Willner, Yang Xiao, Hye Sung Kim, Xuejing Chen, Bin Xu, Kam W. Leong · 2021 · Journal of Tissue Engineering
  21. Transplantation in the nonhuman primate MPTP model of Parkinson's disease: update and perspectives
    Florence Wianny, Julien Vezoli · 2017 · Primate Biology
  22. Update on forebrain evolution: From neurogenesis to thermogenesis
    Verónica Martínez‐Cerdeño, Fernando García‐Moreno, Maria Antonietta Tosches, András Csillag, Paul R. Manger, Zoltán Molnár · 2017 · Seminars in Cell and Developmental Biology
  23. Comprehensive and cell‐type‐based characterization of the dorsal midbrain during development
    Nariko Arimura, Ken‐ichi Dewa, Mako Okada, Yuchio Yanagawa, Shinichiro Taya, Mikio Hoshino · 2018 · Genes to Cells
  24. Genome-Wide Identification of HES1 Target Genes Uncover Novel Roles for HES1 in Pancreatic Development
    Kristian Honnens de Lichtenberg, Nina Sofi Funa, Nikolina Nakić, Jorge P. Ferrer, Zeng‐Rong Zhu, Danwei Huangfu, Palle Serup · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  25. Cell type-specific enhancer-promoter connectivity maps in the human brain and disease risk association
    A. Nott, I. Holtman, N. Coufal, J. Schlachetzki, Miao Yu, Rong Hu, Claudia Z. Han, Monique Pena, Jiayang Xiao, Yin Wu et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  26. Bayesian inference of the gene expression states of single cells from scRNA-seq data
    Jérémie Breda, Mihaela Zavolan, Erik van Nimwegen · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  27. An atlas of GPCRs in dopamine neurons: Identification of the free fatty acid receptor 4 as a regulator of food and water intake
    Mia Apuschkin, Hayley B. Burm, Jan Hendrik Schmidt, Louise Julie Skov, Rita Chan Andersen, Carl-Fredrik Bowin, Jonatan Fullerton Støier, Kathrine Louise Jensen, Leonie P. Posselt, Oksana Dmytriyeva et al. · 2024 · Cell Reports
  28. The Genetic Architecture of the Human Corpus Callosum and its Subregions
    Ravi R. Bhatt, Shruti P. Gadewar, Ankush Shetty, Iyad Ba Gari, Elizabeth Haddad, Shayan Javid, Abhinaav Ramesh, Elnaz Nourollahimoghadam, Alyssa H. Zhu, Christiaan de Leeuw et al. · 2025 · Nature Communications
  29. Disentangling individual heterogeneity reveals robust network and molecular signatures of major depressive disorder with suicidal ideation
    Yunheng Diao, Yuanyuan Huang, Minxin Guo, Wenhao Li, Wei Wang, Zhaobo Li, Heng Zhang, Jing Zhou, Xiaobo Li, Fengchun Wu et al. · 2026 · Translational Psychiatry
  30. Synapsin III Regulates Dopaminergic Neuron Development in Vertebrates
    Gaia Faustini, Francesca Longhena, Alessia Muscò, Federica Bono, Edoardo Parrella, Luca La Via, Alessandro Barbon, Marina Pizzi, Franco Onofri, Fabio Benfenati et al. · 2022 · Cells
  31. Viral vector-mediated transgene delivery with novel recombinase systems for targeting neuronal populations defined by multiple features
    Minju Jeong, Jun‐Hyeok Choi, Hyeonseok Jang, Dong Hyun Sohn, Qingdi Wang, Joann Lee, Yao Li, Eun Ji Lee, Jiachen Fan, Marta Pratelli et al. · 2023 · Neuron
  32. Dynamic Insights into Dopamine Axon Growth in Adolescence and its Implications for Psychiatric Risk
    Radu Gabriel Avramescu, Tanya Capolicchio, Cecilia Flores · 2024 · Current Opinion in Behavioral Sciences
  33. Circular RNAs regulate neuron size and migration of midbrain dopamine neurons during development
    Mateja Rybiczka-Tešulov, Oxana Garritsen, Morten Trillingsgaard Venø, Laura Wieg, Roland E. van Dijk, Karim Rahimi, Andreia Gomes‐Duarte, Marina de Wit, Lieke L. van de Haar, Lars Michels et al. · 2024 · Nature Communications
  34. Genomic evolution reshapes cell-type diversification in the amniote brain
    Duoyuan Chen, Zhenkun Zhuang, Maolin Huang, Yunqi Huang, Yuting Yan, Yanru Zhang, Youning Lin, Xiaoying Jin, Yuanmei Wang, Jinfeng Huang et al. · 2025 · Developmental Cell
  35. Trophoblast glycoprotein is a new candidate gene for Parkinson’s disease
    Sanghyun Park, Jeong‐Eun Yoo, Gyu‐Bum Yeon, Jin Hee Kim, Jae Souk Lee, Sung Kyoung Choi, Young-Gi Hwang, Chan Wook Park, Myung Soo Cho, Jongwan Kim et al. · 2021 · npj Parkinson s Disease
  36. Combinatorial ECM Arrays Identify Cooperative Roles for Matricellular Proteins in Enhancing the Generation of TH+ Neurons From Human Pluripotent Cells
    Maqsood Ahmed, Matthew Owens, Enrique M. Toledo, Ernest Arenas, Mark Bradley, Charles ffrench‐Constant · 2021 · Frontiers in Cell and Developmental Biology
  37. An NMF-based approach to discover overlooked differentially expressed gene regions from single-cell RNA-seq data
    Hirotaka Matsumoto, Tetsutaro Hayashi, Haruka Ozaki, Koki Tsuyuzaki, Mana Umeda, Tsuyoshi Iida, Masaya Nakamura, Hideyuki Okano, Itoshi Nikaido · 2019 · NAR Genomics and Bioinformatics
  38. PseudoGA: cell pseudotime reconstruction based on genetic algorithm
    Pronoy Kanti Mondal, Udit Surya Saha, Indranil Mukhopadhyay · 2021 · Nucleic Acids Research
  39. Single cell atlas of domestic pig brain illuminates the conservation and divergence of cell types at spatial and species levels
    Dongsheng Chen, Jiacheng Zhu, Jixing Zhong, Fang Chen, Xiumei Lin, Jinxia Dai, Yin Chen, Shiyou Wang, Xiangning Ding, Haoyu Wang et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  40. A developmental atlas of the mouse brain by single-cell mass cytometry
    Amy Lynnette Van Deusen, Sarah M. Goggin, Corey M. Williams, Austin B. Keeler, Kristen Fread, Irene Cheng, Christopher D. Deppmann, Eli R. Zunder · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  41. APOE3 Christchurch modulates tau phosphorylation and β-catenin/Wnt/Cadherin signaling in induced pluripotent stem cell-derived cerebral organoids from Alzheimer’s cases
    Randall C. Mazzarino, Paula Andrea Perez-Corredor, Timothy E. Vanderleest, Guido N. Vacano, Justin S. Sanchez, Nelson David Villalba‐Moreno, S Krausemann, MA Mendivil-Perez, David Fernando Aguillon, Marlene Jiménez-Del-Río et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  42. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
    Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlmann · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  43. A contextual genomic perspective on physical activity and its relationship to health, well being and illness
    Marco Galimberti, Daniel F. Levey, Joseph D. Deak, Keyrun Adhikari, Cassie M. Overstreet, Priya Dhamija Gupta, Rachana Nitin, Hang Zhou, Nicole J. Lake, Kelly M. Harrington et al. · 2025 · Nature Genetics
  44. 3D-generation of high-purity midbrain dopaminergic progenitors and lineage-guided refinement of grafts supports Parkinson’s disease cell therapy
    Xinyue Zhang, Ziyan Wu, Hui He, Qian Guan, Qike Ouyang, Rongjing Wang, Lianshun Xie, Yingying Zhou, Ban Feng, Zinan Luo et al. · 2025 · Cell stem cell
  45. Stress resilience is associated with transcriptional remodeling in the VTA
    Adelaide R. Minerva, Brenna McMannon, Rixing Lin, Anna Zhukovskaya, Ilana B. Witten, Catherine J. Peña · 2026 · Cell Reports
  46. Human LUHMES and NES cells as models for studying primary cilia in neurons
    Andrea Coschiera, Michelle Evelyn Watts, Juha Kere, Kristiina Tammimies, Peter Swoboda · 2023 · Methods in cell biology
  47. Extracellular matrix protein anosmin-1 overexpression alters dopaminergic phenotype in the CNS and the PNS with no pathogenic consequences in a MPTP model of Parkinson’s disease
    Javier Villadiego, Roberto García‐Swinburn, Diego García‐González, Rafael Lebrón‐Galán, Verónica Murcia‐Belmonte, Ernesto García‐Roldán, Nela Suárez‐Luna, Cristina Nombela, Miguel Marchena, Fernando de Castro et al. · 2023 · Brain Structure and Function
  48. Exploring the optimization of autoencoder design for imputing single-cell RNA sequencing data
    Nan Miles Xi, Jingyi Jessica Li · 2023 · Computational and Structural Biotechnology Journal
  49. The Phylotypic Brain of Vertebrates, from Neural Tube Closure to Brain Diversification
    Rodrigo Senovilla-Ganzo, Fernando García‐Moreno · 2024 · Brain Behavior and Evolution
  50. Spatial Omics: Navigating Neuroscience Research into the New Era
    Pengfei Guo, Yanxiang Deng · 2024 · Advances in neurobiology
  51. Identifying Common Genes, Cell Types and Brain Regions Between Diseases of the Nervous System
    Mengling Qi, Shichao Fan, Zhi Wang, Xiaoxing Yang, Zicong Xie, Ken Chen, Lei Zhang, Tao Lin, Wei Liu, Xinlei Lin et al. · 2019 · Frontiers in Genetics
  52. Dementia with Lewy bodies post-mortem brains reveal differentially methylated CpG sites with biomarker potential
    Xiaojian Shao, Sangeetha Vishweswaraiah, Miroslava Čuperlović‐Culf, Ali Yılmaz, Celia M.T. Greenwood, Anuradha Surendra, Bernadette McGuinness, Peter Passmore, Patrick G. Kehoe, Michael E. Maddens et al. · 2022 · Communications Biology
  53. Single-nuclei RNA sequencing uncovers heterogenous transcriptional signatures in Parkinson’s disease associated with nuclear receptor-related factor 1 defect
    Piniel Alphayo Kambey, Wen-Ya Liu, Jiao Wu, Bakwatanisa Bosco, Iqra Nadeem, Kouminin Kanwore, Dianshuai Gao · 2023 · Neural Regeneration Research
  54. Iterative Systems Biology for Medicine – Time for advancing from network signatures to mechanistic equations
    David Gómez-Cabrero, Jesper N. Tegner · 2017 · Current Opinion in Systems Biology
  55. SSMD: a semi-supervised approach for a robust cell type identification and deconvolution of mouse transcriptomics data
    Xiaoyu Lu, Szu-wei Tu, Wennan Chang, Changlin Wan, Jiashi Wang, Yong Zang, Baskar Ramdas, Reuben Kapur, Xiongbin Lu, Sha Cao et al. · 2020 · Briefings in Bioinformatics
  56. Disentangling the Molecular Pathways of Parkinson’s Disease using Multiscale Network Modeling
    Qian Wang, Bin Zhang, Zhenyu Yue · 2021 · Trends in Neurosciences
  57. Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha‐6 chain as a novel regulator of striatal axonal branching in mice
    Mélanie H. Thomas, Yujuan Gui, Pierre Garcia, Mona Karout, Borja Gomez Ramos, Christian Jaeger, Alessandro Michelucci, Anthoula Gaigneaux, Heike Kollmus, Arthur G. Centeno et al. · 2021 · Genes Brain & Behavior
  58. DKK1 expression is suppressed by miR-9 during induced dopaminergic differentiation of human trabecular meshwork mesenchymal stem cells
    Elham Sadat Mirfazeli, Ehsan Arefian, Samad Nadri, Rezvan Rezazadeh Valojerdi, Mousa Kehtari, Bahman Zeynali · 2019 · Neuroscience Letters
  59. [Minimally invasive surgery for lung cancer using thoracoscope as a 'microscopic surgery'; for the safety endoscopic surgery].
    Keishi Kondo, Hiroshi Adachi · 2006 · PubMed
  60. Single Cell Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson’s Disease
    Katarína Tiklová, Sara Nolbrant, Alessandro Fiorenzano, Åsa K. Björklund, Yogita Sharma, Andreas Heuer, Linda Gillberg, Deirdre B. Hoban, Tiago Cardoso, Andrew F. Adler et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
  61. Spatial RNA sequencing identifies robust markers of vulnerable and resistant human midbrain dopamine neurons and their expression in Parkinson’s Disease
    Julio Aguila Benitez, Shangli Cheng, Nigel Kee, Ming Cao, Menghan Wang, Qiaolin Deng, Eva Hedlund · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  62. Dissecting Autism Genetic Risk Using Single-cell RNA-seq Data
    Siying Chen, Xueya Zhou, Eve Byington, Samuel L. Bruce, Haicang Zhang, Yufeng Shen · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  63. Neuron-type specificity of dorsal raphe projections to ventral tegmental area
    Anna J. Chang, Lihua Wang, Federica Lucantonio, Maya Adams, Andrew L. Lemire, Joshua Tate Dudman, Jeremiah Y. Cohen · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  64. Multi-omic human neural organoid cell atlas of the posterior brain
    Nadezhda V. Azbukina, Zhisong He, Hsiu‐Chuan Lin, Małgorzata Santel, Bijan Kashanian, Ashley Maynard, Tivadar Torok, Ryoko Okamoto, Marina Tsvetomilova Nikolova, Sabina Kanton et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  65. Parkinson’s Disease-vulnerable and -resilient dopamine neurons display opposite responses to excitatory input
    Lotfi C. Hadjas, Grace J Kollman, Lexe Linderhof, Min Xia, Syon Mansur, Martine Saint‐Pierre, Byung Kook Lim, Edward B. Lee, Francesca Cicchetti, Rajeshwar B. Awatramani et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
  66. An integrated single cell and spatial omics atlas of human prenatal development
    Simone Webb, Antony Rose, Chuan Xu, Lloyd Steele, Masami A Kuri, Emily Stephenson, Kemal İnecik, Daniyal J. Jafree, April Rose Foster, Daniela Basurto-Lozada et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
  67. Human Midbrain Organoids Enriched With Dopaminergic Neurons for Long‐Term Functional Evaluation
    Xinyue Wang, Gaoying Sun, Mingming Tang, Da Li, Jianhuan Qi, Chuanyue Wang, Yukai Wang, Baoyang Hu · 2025 · Cell Proliferation
  68. Neural stem cells of the subventricular zone: A potential stem cell pool for brain repair in Parkinson’s disease
    Marloes Verkerke, Maarten H Werkman, Vanessa Donega · 2025 · Stem Cell Reports
  69. ETMR stem-like state and chemo-resistance are supported by perivascular cells at single-cell resolution
    Flavia W. de Faria, Nicole C. Riedel, Daniel Münter, Marta Interlandi, Carolin Göbel, Lea Altendorf, Mathis Richter, Viktoria Melcher, Christian Thomas, Rajanya Roy et al. · 2025 · Nature Communications
  70. Co-Conservation of synaptic gene expression and circuitry in collicular neurons
    Yuanming Liu, John A. McDaniel, Chen Chen, Lu Yang, Arda Kıpçak, Elise Laura Savier, Alev Erişir, Jianhua Cang, John N. Campbell · 2025 · Nature Communications
  71. Integrated Multi‐Omics Analysis and Cross‐Model Validation Reveal Mitochondrial Signatures in Alzheimer's Disease
    Xuan Xu, Shasha Fan, Li Jiang, Hao Wu, Junwen He, Yang He, Xiangyu Meng, Yin Shen · 2025 · CNS Neuroscience & Therapeutics
  72. Investigating the neurodevelopmental toxicity of graphene oxides using 3D human brain organoids and zebrafish models: emphasis on GABAergic neuron alterations at single-cell resolution
    Yuna Chen, Weichao Zhao, Lu Gan, Chaobo Huang, Xudong Liu, Dingxin Long, Yi Cao · 2025 · Chemico-Biological Interactions
  73. An in vivo and in vitro spatiotemporal profile of human midbrain development
    Dimitri Budinger, Pau Puigdevall, George T. Hall, Charlotte Roth, Theodoros A. Xenakis, Elena Marrosu, Julie Jerber, Alessandro Di Domenico, Francesca Picco, Helena Kilpinen et al. · 2026 · Nature Communications
  74. Reconstructing human corticogenesis: Insights from cerebral organoids into neurodevelopment and disease modeling
    Miguel F. Tenreiro, Alysson Renato Muotri · 2026 · Developmental Cell
  75. MicroRNA expression profiling of urine exosomes in children with congenital cytomegalovirus infection
    Yuka Torii, Takako Suzuki, Yuto Fukuda, Kazunori Haruta, Makoto Yamaguchi, Kazuhiro Horiba, Jun‐ichi Kawada, Yoshinori Ito · 2024 · Scientific Reports
  76. SAE-Impute: imputation for single-cell data via subspace regression and auto-encoders
    Liang Bai, Boya Ji, Shulin Wang · 2024 · BMC Bioinformatics
  77. New Multiomic Studies Shed Light on Cellular Diversity and Neuronal Susceptibility in Parkinson's Disease
    Marianna Liang, L. M. Chu, Zhenyu Yue · 2025 · Movement Disorders
  78. Applications of single‐cell multi‐omics sequencing in deep understanding of brain diseases
    Xu Zhang, Ping Lü, Xiaorong Shen · 2022 · Clinical and Translational Discovery
  79. dsCellNet: A new computational tool to infer cell–cell communication networks in the developing and aging brain
    Zhihong Song, Ting Wang, Yan Wu, Ming Fan, Haitao Wu · 2022 · Computational and Structural Biotechnology Journal
  80. Organ-Chips Enhance the Maturation of Human iPSC-Derived Dopamine Neurons
    María Gabriela Otero, Shaughn Bell, Alex Laperle, George M. Lawless, Zachary Myers, Marian A. Castro, Jaquelyn M. Villalba, Clive Niels Svendsen · 2023 · International Journal of Molecular Sciences
  81. Computing Minimal Boolean Models of Gene Regulatory Networks
    Guy Karlebach, Peter N. Robinson · 2023 · Journal of Computational Biology
  82. LRP10 and α-synuclein transmission in Lewy body diseases
    Ana Carreras Mascaro, Martyna M. Grochowska, Valerie Boumeester, Natasja F. J. Dits, Ece Naz Bilgiҫ, Guido J. Breedveld, Leonie J.M. Vergouw, Frank Jan de Jong, Martin E. van Royen, Vincenzo Bonifati et al. · 2024 · Cellular and Molecular Life Sciences
  83. Citalopram exposure of hESCs during neuronal differentiation identifies dysregulated genes involved in neurodevelopment and depression
    Mari Spildrejorde, Magnus Leithaug, ATHINA A. SAMARA, Hans Christian D. Aass, Ankush Sharma, Ganesh Acharya, Hedvig Nordeng, Kristina Gervin, Robert Lyle · 2024 · Frontiers in Cell and Developmental Biology
  84. CelltypeR: A flow cytometry pipeline to characterize single cells from brain organoids
    Rhalena A. Thomas, Julien Sirois, Shu-Ming Li, Alexandre Gestin, Ghislaine Deyab, Valerio E. C. Piscopo, Paula Lépine, Meghna Mathur, Carol X.‐Q. Chen, Vincent Soubannier et al. · 2024 · iScience
  85. Deconvolution from bulk gene expression by leveraging sample-wise and gene-wise similarities and single-cell RNA-seq data
    Chenqi Wang, Yifan Lin, Shuchao Li, Jinting Guan · 2024 · BMC Genomics
  86. Molecular heterogeneity and development of the ventral tegmental area
    Catherine J. Peña, Michael DeBerardine, Kaitlin E. Sullivan · 2024 · Current Opinion in Behavioral Sciences
  87. Spatiotemporal proteomic and transcriptomic landscape of DAT+ dopaminergic neurons development and function
    Heyu Zhao, Peipei Chen, Xia Gao, Zhi‐Li Huang, Pengyuan Yang, Huali Shen · 2025 · iScience
  88. Bioinformatic and biological avenues for understanding alcohol use disorder
    Emily K. Grantham, Sean P. Farris · 2018 · Alcohol
  89. Investigating Cell Fate Decisions with ICGS Analysis of Single Cells
    Nathan Salomonis · 2019 · Methods in molecular biology
  90. Cryopreserved clinical-grade human embryonic stem cell-derived dopaminergic progenitors function in Parkinson's disease models
    Somayeh Naderi, Zahra Shiri, Masoumeh Zarei‐Kheirabadi, Sepideh Mollamohammadi, Parastoo Hosseini, Golnoosh Rahimi, Azadeh Moradmand, Azam Samadian, Amir Shojaei, Meghdad Yeganeh et al. · 2023 · Life Sciences
  91. Sequencing the Human Brain at Single-Cell Resolution
    Malosree Maitra, Corina Nagy, Gustavo Turecki · 2019 · Current Behavioral Neuroscience Reports
  92. Alzheimer's disease: the large gene instability hypothesis
    Sourena Soheili‐Nezhad · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  93. Cnidarian cell type diversity revealed by whole-organism single-cell RNA-seq analysis
    Arnau Sebé-Pedrós, Elad Chomsky, Baptiste Saudememont, Marie-Pierre Mailhé, Flora Pleisser, Justine Renno, Yann Loe-Mie, Aviezer Lifshitz, Zohar Mukamel, Sandrine Schmutz et al. · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
  94. Hedgehog signaling activates a heterochronic gene regulatory network to control differentiation timing across lineages
    Megan Rowton, Carlos Perez-Cervantes, Ariel B. Rydeen, Suzy S. J. Hur, Jessica Jacobs-Li, Nikita Deng, Emery Lu, Alexander Guzzetta, Jeffrey D. Steimle, Andrew Daniel Hoffmann et al. · 2018 · bioRxiv (Cold Spring Harbor Laboratory)
  95. Reference-based cell type matching of spatial transcriptomics data
    Yun Zhang, Jeremy A. Miller, Jeongbin Park, Boudewijn P. F. Lelieveldt, Brian Long, Tamim Abdelaal, Brian D. Aevermann, Tommaso Biancalani, Charles S. Comiter, Oleh Dzyubachyk et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  96. Distributional coding of associative learning within projection-defined populations of midbrain dopamine neurons
    Riccardo Avvisati, Anna-Kristin Kaufmann, Callum J. Young, Gabriella E. Portlock, Sophie Cancemi, Rui Ponte Costa, Peter J. Magill, Paul D. Dodson · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
  97. Overlapping representations of food and social stimuli in VTA dopamine neurons
    Lindsay Willmore, Adelaide R. Minerva, Ben Engelhard, Malavika Murugan, Brenna McMannon, Nirja Oak, Stephan Y. Thiberge, Catherine J. Peña, Ilana B. Witten · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  98. Sexually dimorphic mechanisms of VGLUT-mediated protection from dopaminergic neurodegeneration
    Silas A. Buck, Sophie A. Rubin, Tenzin Kunkhyen, Christoph D. Treiber, Xiangning Xue, Lief E. Fenno, Samuel J. Mabry, Varun R. Sundar, Zilu Yang, Divia Shah et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  99. Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson’s disease
    Kyriaki Barmpa, Cláudia Saraiva, Gemma Gomez‐Giro, Elisa Gabassi, Sarah Spitz, Konstanze Brandauer, Juan Eduardo Rodriguez-Gatica, Paul M. A. Antony, Graham Robertson, Florentia Papastefanaki et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
  100. An RNA-seq atlas of mouse brain areas during fasting and diet-induced obesity
    Petar V. Todorov, Anders Bue Klein, Kristoffer Lihme Egerod, Christoffer Clemmensen, Tune H. Pers · 2024 · Scientific Data