Molecular diversity of midbrain development in mouse, human, and stem cells

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Items 601–700 of 842

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2. Characterizing enteric neurons in dopamine transporter (DAT)‐Cre reporter mice reveals dopaminergic subtypes with dual‐transmitter content
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8. Building Immunocompetent Cerebral Organoids From a Developmental Perspective
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12. Differential Network Analysis Reveals Regulatory Patterns in Neural Stem Cell Fate Decision
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13. Generation of a NES-mScarlet Red Fluorescent Reporter Human iPSC Line for Live Cell Imaging and Flow Cytometric Analysis and Sorting Using CRISPR-Cas9-Mediated Gene Editing
    Parivash Nouri, Anja Zimmer, Stefanie Brüggemann, Robin Friedrich, Ralf Kühn, Nilima Prakash · 2022 · Cells
14. Computational Methods to Identify Cell-Fate Determinants, Identity Transcription Factors, and Niche-Induced Signaling Pathways for Stem Cell Research
    Muhammad Ali, Mariana Messias Ribeiro, Antonio del Sol · 2022 · Methods in molecular biology
15. TGFβ3, dibutyryl cAMP and a notch inhibitor modulate phenotype late in stem cell-derived dopaminergic neuron maturation
    Shanti M. Sibuea, Joan K. Ho, Colin William Pouton, John M. Haynes · 2023 · Frontiers in Cell and Developmental Biology
16. Inhibitory neuron map of sevoflurane induced neurotoxicity model in young primates
    Yixuan Niu, Yanyong Cheng, Zhengjie Miao, Jinnan Xu, Hong Jiang, Jia Yan · 2023 · Frontiers in Cellular Neuroscience
17. Human Stem Cell–Derived Models: Lessons for Autoimmune Diseases of the Nervous System
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18. Information topology of gene expression profile in dopaminergic neurons
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19. Spatial organization of cells and variable expression of autophagy, apoptosis, and neurodevelopmental genes might underlie selective brain region vulnerability in Attention-Deficit/Hyperactivity Disorder
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20. High sensitivity (zeptomole) detection of BODIPY heparan sulfate (HS) disaccharides by ion-paired RP-HPLC and LIF detection enables analysis of HS from mosquito midguts
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21. Wnt signaling mediates acquisition of blood-brain barrier properties in naïve endothelium derived from human pluripotent stem cells
    Benjamin D. Gastfriend, Hideaki Nishihara, Scott Glen Canfield, Koji L. Foreman, Britta Engelhardt, Sean P. Palecek, Eric V. Shusta · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
22. Bioenergetic-Related Gene Expression in the Hippocampus Predicts Internalizing vs. Externalizing Behavior in a F 2 Cross of Selectively-Bred Rats
    Elaine K. Hebda‐Bauer, Megan Hastings Hagenauer, Daniel B. Munro, Peter Blandino, Fan Meng, Keiko Arakawa, Apurva S. Chitre, Ayse Bilge Ozel, Pejman Mohammadi, Stanley J. Watson et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
23. Conserved coexpression at single cell resolution across primate brains
    Hamsini Suresh, Megan Crow, Nikolas L. Jorstad, Rebecca D. Hodge, Ed S. Lein, Alexander Dobin, Trygve E. Bakken, Jesse A Gillis · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
24. Air-liquid interface culture of midbrain organoids improves neuronal functionality and integration of microglia
    Sara Kälvälä, Polina A. Abushik, Antonios Dougalis, Tarja Malm, Anssi Pelkonen, Šárka Lehtonen · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
25. Molecular and spatial transcriptomic classification of midbrain dopamine neurons and their alterations in a LRRK2G2019S model of Parkinson’s disease
    Zachary A. Gaertner, Cameron Oram, Amanda K. Schneeweis, Elan Schonfeld, Cyril Bolduc, Chuyu Chen, Daniel A. Dombeck, Loukia Parisiadou, Jean Francois Poulin, Rajeshwar B. Awatramani · 2024 · eLife
26. A human developmental and adult brain atlas benchmarks dopaminergic stem cell models and cell therapy candidates
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27. Translating stress systems: corticotropin releasing factor, its receptors, and the dopamine system in nonhuman primate models
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28. IGCLAPS: an interpretable graph contrastive learning method with adaptive positive sampling for scRNA-seq data analysis
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29. Engineering human neuronal diversity: Morphogens and stem cell technologies for neurodevelopmental biology
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30. Distinct spatial patterning and transcriptomic landscapes of human neural organoids by localized delivery of morphogens
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31. Cross-species transcriptomics reveals bifurcation point during the arterial-to-hemogenic transition
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32. A review article on the development of dopaminergic neurons and establishment of dopaminergic neuron–based in vitro models by using immortal cell lines or stem cells to study and treat Parkinson's disease
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33. Integrating spatial transcriptomics and snRNA-seq data enhances differential gene expression analysis results of AD-related phenotypes
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34. VBASS enables integration of single cell gene expression data in Bayesian association analysis of rare variants
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35. A dual‐omics approach on the effects of fibroblast growth factor‐2 (FGF‐2) on ventral tegmental area dopaminergic neurons in response to alcohol consumption in mice
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36. Autism patient-derived SHANK2BY29X mutation affects the development of ALDH1A1 negative dopamine neuron
    Wanjing Lai, Yingying Zhao, Yalan Chen, Zhenzhu Dai, Ruhai Chen, Yimei Niu, Xiaoxia Chen, Shuting Chen, Guanqun Huang, Ziyun Shan et al. · 2024 · Molecular Psychiatry
37. BrainTACO: an explorable multi-scale multi-modal brain transcriptomic and connectivity data resource
    Florian Ganglberger, Dominic Kargl, Markus Töpfer, Julien Hernandez-Lallement, Nathan Lawless, Francesc Fernández-Albert, Wulf E. Haubensak, Katja Bühler · 2024 · Communications Biology
38. Cross-species comparison of airway epithelium transcriptomics
    Biyu Gui, Qi Wang, Jianhai Wang, Xue Li, Qi Wu, Huaiyong Chen · 2024 · Heliyon
39. scMUG: deep clustering analysis of single-cell RNA-seq data on multiple gene functional modules
    De-Min Liang, Pu-Feng Du · 2025 · Briefings in Bioinformatics
40. Lineage Analysis ofCxcr4-Expressing Cells in the Developing Midbrain Suggests That Progressive Competence Restriction in Dopaminergic Progenitor Cells Contributes to the Establishment of Dopaminergic Neuronal Diversity
    Alessandro Petese, Franca Laura Fries, Bianca Broske, Ralf K. Stumm, Sandra Blaess · 2022 · eNeuro
41. Summing up the parts of the hypothalamus
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42. Molecular analysis of the midbrain dopaminergic niche during neurogenesis
    Enrique M. Toledo, Gioele La Manno, Pia Rivetti di Val Cervo, Daniel Gyllborg, Saiful Islam, Carlos Villaescusa, Sten Linnarsson, Ernest Arenas · 2017 · bioRxiv (Cold Spring Harbor Laboratory)
43. Brunner Syndrome associated MAOA dysfunction in human induced dopaminergic neurons results in dysregulated NMDAR expression and increased network activity
    Yufang Shi, J.R. van Rhijn, Maren Bormann, Britt Mossink, Monica Frega, Marina Hakobjan, Sarah Kittel‐Schneider, Dirk Schubert, Han G. Brunner, Barbara Franke et al. · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
44. Single cell transcriptional and functional analysis of human dopamine neurons in 3D fetal ventral midbrain organoid like cultures
    Marcella Birtele, Yogita Sharma, Petter Storm, Janko Kajtez, Jenny Nelander Wahlestedt, Edoardo Sozzi, Fredrik Nilsson, Simon Stott, Xiaoling He, Bengt Mattsson et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
45. Human Developmental Cell Atlas: milestones achieved and the roadmap ahead
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46. Factorial state-space modelling for kinetic clustering and lineage inference
    Revant Gupta, Manfred Claassen · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
47. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
    Behzad Yaghmaeian Salmani, Laura Lahti, Linda Gillberg, Jesper Kjaer Jacobsen, Ioannis Mantas, Per Svenningsson, Thomas Perlmann · 2024 · eLife
48. A single dose of cocaine rewires the 3D genome structure of midbrain dopamine neurons
    Dominik Szabó, Vedran Franke, Simona Bianco, Mykhailo Y. Batiuk, Eleanor J. Paul, Alexander Kukalev, Ulrich Pfisterer, Ibai Irastorza-Azcárate, Andrea M. Chiariello, Samuel Demharter et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
49. Evidence for Dopamine Abnormalities Following Acute Methamphetamine Exposure Assessed by Neuromelanin-Sensitive Magnetic Resonance Imaging
    Fei Tang, Hui Liu, Xiao Jie Zhang, Hui Zheng, Yong Ming Dai, Li Yun Zheng, Wen Han Yang, Yan Yao Du, Jun Liu · 2022 · Frontiers in Aging Neuroscience
50. Sialic acid and PirB are not required for targeting of neural circuits by neurotropic mammalian orthoreovirus
    Kira A. Griswold, Iaroslavna Vasylieva, Megan C. Smith, Kay L. Fiske, Olivia L. Welsh, Alexa N. Roth, Alan M. Watson, Simon C. Watkins, Danica M. Sutherland, Terence S. Dermody · 2024 · mSphere
51. JMJD3 deficiency disturbs dopamine biosynthesis in midbrain and aggravates chronic inflammatory pain
    Xi‐Biao He, Fang Guo, Wei Zhang, Jiacheng Fan, Weidong Le, Qi Chen, Yongjun Ma, Yong Zheng, Sang‐Hun Lee, Huijing Wang et al. · 2024 · Acta Neuropathologica Communications
52. Graft ischemia post cell transplantation to the brain: Glucose deprivation as the primary driver of rapid cell death
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53. A global overview of shared genetic architecture between smoking behaviors and major depressive disorder in European and East Asian ancestry
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54. Bioenergetic-related gene expression in the hippocampus predicts internalizing vs. externalizing behavior in an animal model of temperament
    Elaine K. Hebda‐Bauer, Megan Hastings Hagenauer, Daniel B. Munro, Peter Blandino, Fan Meng, Keiko Arakawa, John D. H. Stead, Apurva S. Chitre, Ayse Bilge Ozel, Pejman Mohammadi et al. · 2025 · Frontiers in Molecular Neuroscience
55. Reference Vector-guided Evolutionary Algorithm for cluster analysis of single-cell transcriptomes
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56. Super‐Resolution Compatible DNA Labeling Technique Reveals Chromatin Mobility and Organization Changes During Differentiation
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57. In vitro derivation of midbrain dopaminergic neurons from porcine embryonic stem cells in multi-dimensional conditions
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58. A novel paradigm for single-cell annotation in stem cell research
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59. Single-Cell Profiling Identifies Reward Behavior-Related Neurons and Alterations in the Ventral Tegmental Area Based on Arvcf -Knockout Mouse Model
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61. Distinct radial glia subtypes regulate midbrain dopaminergic neuron development
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63. Single-cell multi-omic atlas and morphogen screening informs midbrain and hindbrain organoid engineering
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64. POINTseq: Cell-type-specific barcoding reveals single-cell projection architecture of the mouse dopaminergic system
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65. An atlas of primate insular cortex reveals a signal-processing strategy in von Economo neurons
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66. Paclitaxel is effective for controlling astrocyte proliferation in vitro: Implications for generating ventral mesencephalic cultures enriched with dopamine neurons
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67. Interactome overlap between risk genes of epilepsy and targets of anti-epileptic drugs
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68. scHOIS: Determining Cell Heterogeneity Through Hierarchical Clustering Based on Optimal Imputation Strategy
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69. Increased sucrose consumption in mice gene-targeted for Vmat2 selectively in NeuroD6-positive neurons of the ventral tegmental area
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70. scTSSR-D: Gene Expression Recovery by Two-side Self-Representation and Dropout Information for scRNA-seq Data
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71. Single-cell Technology in Stem Cell Research
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72. Neurotransmitters and Endothelins Acting on Radial Glial G-Protein-Coupled Receptors Are, Through Proteolytic NRG/ErbB4 Activation, Able to Modify the Migratory Behavior of Neocortical Cells and Mediate Bipolar-to-Multipolar Transition
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73. 3D COMBO chrRNA–DNA–ImmunoFISH
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74. Timing of MeCP2 Expression Determines Midbrain Dopamine Neuron Phenotype Specification
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75. Expression and role of nicotinic acetylcholine receptors during midbrain dopaminergic neuron differentiation from human induced pluripotent stem cells
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76. Distinct evolutionary trajectories of neuronal and hair cell nicotinic acetylcholine receptors
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77. Secondary single-cell transcriptomic analysis reveals common molecular signatures of cerebrovascular injury between traumatic brain injury and aging
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80. Neurovascular development
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81. Transcriptomic atlas of midbrain dopamine neurons uncovers differential vulnerability in a Parkinsonism lesion model
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84. Aldh1a1 and additional markers of dopamine cell heterogeneity in substantia nigra and ventral tegmental area identified as preserved in two transgenic α-synuclein mouse models of neurodegenerative disease
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85. Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types
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86. Deconvolving Bulk Transcriptomics Samples to Obtain Cell Type Proportion Estimates
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88. Calbindin stratifies midbrain dopaminergic neurons governing distinct aspects of locomotion
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90. Leucine-rich repeat kinase 2 impairs the release sites of Parkinson’s disease vulnerable dopamine axons
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92. Single-cell transcriptomics revealed molecular vulnerability in a human midbrain-like organoid model of Parkinson’s disease
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93. Engineering functional ventral midbrain dopaminergic neurons in human organoids through WNT modulation and bioreactor culture
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98. Navigating disease phenotypes – A multidimensional single-cell resolution compass leads the way
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99. Nkx2.9 Contributes to Mid-Hindbrain Patterning by Regulation of mdDA Neuronal Cell-Fate and Repression of a Hindbrain-Specific Cell-Fate
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100. scTSSR2: Imputing Dropout Events for Single-Cell RNA Sequencing Using Fast Two-Side Self-Representation
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