Genomic and transcriptomic features of response to anti-PD-1 therapy in metastatic melanoma

Hugo, Willy, Zaretsky, Jesse M., Sun, Lu, Song, Chunying, Moreno, Blanca Homet, Hu-Lieskovan, Siwen, Berent-Maoz, Beata, Pang, Jia +10 more·2017·Cell
DOI 10.1016/j.cell.2017.01.010

Cited by (494)

Items 401–494 of 494

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  8. Whole-genome sequencing uncovers the genomic determinants of therapeutic resistance to immune checkpoint blockade
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  11. Additional file 5 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stan Gu, Xiaoqing Wang, Xihao Sherlock Hu, Jiang, Peng, Ziyi Li, Nicole C. Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng et al. · 2020 · Figshare
  12. Additional file 2 of Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance
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  13. Additional file 2 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stan Gu, Xiaoqing Wang, Xihao Sherlock Hu, Jiang, Peng, Ziyi Li, Nicole C. Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng et al. · 2020 · Figshare
  14. Additional file 7 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Zewei Tu, Qiankun Ji, Qing Han · 2022 · Figshare
  15. Additional file 4 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stan Gu, Xiaoqing Wang, Xihao Sherlock Hu, Peng Jiang, Ziyi Li, Nicole C. Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng et al. · 2020 · Figshare
  16. Additional file 6 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Zewei Tu, Qiankun Ji, Qing Han · 2022 · Figshare
  17. Additional file 3 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stan Gu, Xiaoqing Wang, Xihao Sherlock Hu, Jiang, Peng, Ziyi Li, Nicole C. Traugh, Xia Bu, Qin Tang, Chenfei Wang, Zexian Zeng et al. · 2020 · Figshare
  18. Integrating Multi-Omics Analysis and Machine Learning to Identify Molecular Subtypes and Construct Prognostic Models for Lung Squamous Cell Carcinoma
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  19. Comprehensive Enumeration of Cancer Stem-like Cell Heterogeneity Using Deep Neural Network
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  20. Palmitate-induced mitochondrial damage restricts histone acetylation in CD8 + T cells to impair anti-tumor immunity
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  21. Unravelling Cancer Immunity: Coagulation.Sig and BIRC2 as Predictive Immunotherapeutic Architects
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  24. Transcriptomic insights: insights into urine biomarkers
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  25. Cell division cycle 20 promotes tumor progression and predicts poor clinical outcome in childhood and adult adrenocortical carcinoma
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  26. Spatial Technologies: A Game Changer for Studying the Tumor Microenvironment
    Ren Yuan Lee, Mai Chan Lau, Denise L M Goh, Felicia Yu Ting Wee, Jeffrey Chun Tatt Lim, Joe Poh Sheng YEONG · 2025 · Springer eBooks
  27. Independent validation of lung adenocarcinoma prognostic risk scores incorporating cholesterol and estrogen metabolism related transcriptional biomarkers
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  28. SLIT2 inhibits lung adenocarcinoma progression by suppressing epithelial-mesenchymal transition
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  29. Additional file 2 of Single-cell N6-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapy
    Yuzhen Gao, Wang, Hao, Chen, Shipeng, Rui An, Chu, Yadong, Li, Guoli, Wang, Yanzhong, Xie, Xinyou, Zhang, Jun · 2022 · Figshare
  30. Additional file 2 of Artificial intelligence learning landscape of triple-negative breast cancer uncovers new opportunities for enhancing outcomes and immunotherapy responses
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  31. Additional file 1 of Identification of a cytokine-dominated immunosuppressive class in squamous cell lung carcinoma with implications for immunotherapy resistance
    Yang, Minglei, Lin, Chenghao, Wang, Yanni, Chen, Kang, Zhang, Haiyue, Li, Weizhong · 2022 · Figshare
  32. Additional file 4 of CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
    Zhang, Xiaofei, Qin Hu, He, Xuesong, Cui, Xinyue, Liang, Zhaoyuan, Wang, Li, Deng, Xiongwei, Zhang, Ze, Wang Sheng, Xiaodong Han · 2023 · Figshare
  33. Additional file 5 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  34. Additional file 4 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  35. Additional file 12 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Ren, Yiqing, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  36. Additional file 6 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  37. Additional file 2 of Burden of tumor mutations, neoepitopes, and other variants are weak predictors of cancer immunotherapy response and overall survival
    Mary Ann Wood, Benjamin R. Weeder, Julianne K. David, Abhinav Nellore, Reid F. Thompson · 2020 · Figshare
  38. Additional file 14 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  39. Additional file 7 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  40. Additional file 1 of Caspase-8 contributes to an immuno-hot microenvironment by promoting phagocytosis via an ecto-calreticulin-dependent mechanism
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  41. Additional file 7 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  42. Additional file 4 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Tu, Zewei, Qiankun Ji, Han, Qing · 2022 · Figshare
  43. Additional file 1 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Ren, Yiqing, Duan, Yingxin, Hangyu Zhang, Tong, Zhou et al. · 2024 · Figshare
  44. Additional file 3 of Artificial intelligence learning landscape of triple-negative breast cancer uncovers new opportunities for enhancing outcomes and immunotherapy responses
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  45. Additional file 3 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  46. Additional file 1 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  47. Additional file 1 of Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer
    Li, Peisi, Zhou, Dawang, Chen, Dongwen, Yikan Cheng, Chen, Yuan, Lin, Zhensen, Zhang, Xi, Huang, Zhihong, Cai, Jiawei, Huang, Wenfeng et al. · 2024 · Figshare
  48. Additional file 1 of Single-cell N6-methyladenosine regulator patterns guide intercellular communication of tumor microenvironment that contribute to colorectal cancer progression and immunotherapy
    Gao, Yuzhen, Wang, Hao, Chen, Shipeng, Rui An, Chu, Yadong, Li, Guoli, Wang, Yanzhong, Xie, Xinyou, Zhang, Jun · 2022 · Figshare
  49. Additional file 6 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stanley Gu Gu, Wang, Xiaoqing, Hu, Xihao, Jiang, Peng, Li, Ziyi, Traugh, Nicole, Bu, Xia, Tang, Qin, Wang, Chenfei, Zexian Zeng et al. · 2020 · Figshare
  50. Additional file 2 of Tumor-secreted IFI35 promotes proliferation and cytotoxic activity of CD8+ T cells through PI3K/AKT/mTOR signaling pathway in colorectal cancer
    Li, Peisi, Zhou, Dawang, Chen, Dongwen, Yikan Cheng, Chen, Yuan, Lin, Zhensen, Zhang, Xi, Huang, Zhihong, Cai, Jiawei, Huang, Wenfeng et al. · 2024 · Figshare
  51. Additional file 2 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Tu, Zewei, Qiankun Ji, Han, Qing · 2022 · Figshare
  52. Additional file 1 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Tu, Zewei, Qiankun Ji, Han, Qing · 2022 · Figshare
  53. Additional file 13 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Ren, Yiqing, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  54. Additional file 8 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Ren, Yiqing, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  55. Additional file 2 of CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
    Zhang, Xiaofei, Hu, Qin, He, Xuesong, Cui, Xinyue, Liang, Zhaoyuan, Li Wang, Deng, Xiongwei, Zhang, Ze, Wang Sheng, Xiaodong Han · 2023 · Figshare
  56. Additional file 3 of CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
    Zhang, Xiaofei, Hu, Qin, He, Xuesong, Cui, Xinyue, Liang, Zhaoyuan, Wang, Li, Deng, Xiongwei, Zhang, Ze, Wang Sheng, Xiaodong Han · 2023 · Figshare
  57. Additional file 11 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  58. Additional file 1 of Clonal tracing reveals diverse patterns of response to immune checkpoint blockade
    Shengqing Stanley Gu Gu, Wang, Xiaoqing, Hu, Xihao, Jiang, Peng, Li, Ziyi, Traugh, Nicole, Bu, Xia, Tang, Qin, Wang, Chenfei, Zexian Zeng et al. · 2020 · Figshare
  59. Additional file 3 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Tu, Zewei, Qiankun Ji, Han, Qing · 2022 · Figshare
  60. Additional file 3 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  61. Additional file 10 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  62. Additional file 1 of CD16 CAR-T cells enhance antitumor activity of CpG ODN-loaded nanoparticle-adjuvanted tumor antigen-derived vaccinevia ADCC approach
    Zhang, Xiaofei, Qin Hu, He, Xuesong, Cui, Xinyue, Liang, Zhaoyuan, Wang, Li, Deng, Xiongwei, Zhang, Ze, Wang Sheng, Xiaodong Han · 2023 · Figshare
  63. Additional file 2 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  64. Additional file 9 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  65. Additional file 2 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  66. Additional file 6 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
  67. Additional file 4 of Comprehensive analysis reveals the prognostic and immunogenic characteristics of DNA methylation regulators in lung adenocarcinoma
    Huang, Jing, Huang, Chujian, Huang, Can · 2024 · Figshare
  68. Additional file 1 of Artificial intelligence learning landscape of triple-negative breast cancer uncovers new opportunities for enhancing outcomes and immunotherapy responses
    Li, Shuyu, Zhang, Nan, Zhang, Hao, Ran Zhou, Li, Zirui, Yang, Xue, Wu, Wantao, Hanning Li, Luo, Peng, Wang, Zeyu et al. · 2024 · Figshare
  69. Additional file 5 of Intrinsic immune evasion patterns predict temozolomide sensitivity and immunotherapy response in lower-grade gliomas
    Tu, Zewei, Qiankun Ji, Han, Qing · 2022 · Figshare
  70. Additional file 5 of S100A9+CD14+ monocytes contribute to anti-PD-1 immunotherapy resistance in advanced hepatocellular carcinoma by attenuating T cell-mediated antitumor function
    Tu, Xiaoxuan, Longxian Chen, Zheng, Yi, Chenglin Mu, Zhang, Zhiwei, Wang, Feiyu, Yiqing Ren, Duan, Yingxin, Zhang, Hangyu, Tong, Zhou et al. · 2024 · Figshare
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