The DOI matches its Crossref record; 54 of the 54 references it cites were found in a registry or an index.
Metabolic Instruction of Immunity
Open accessAbstract
Choices have consequences. Immune cells survey and migrate throughout the body and sometimes take residence in niche environments with distinct communities of cells, extracellular matrix, and nutrients that may differ from those in which they matured. Imbedded in immune cell physiology are metabolic pathways and metabolites that not only provide energy and substrates for growth and survival, but also instruct effector functions, differentiation, and gene expression. This review of immunometabolism will reference the most recent literature to cover the choices that environments impose on the metabolism and function of immune cells and highlight their consequences during homeostasis and disease.
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Cites
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Gut microbiota, metabolites and host immunity
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Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
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Self-citationFunctional Polarization of Tumour-Associated Macrophages by Tumour-Derived Lactic Acid
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Cited by
CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
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Tumor microenvironment complexity and therapeutic implications at a glance
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“Since antitumor immunity suppression is progressively tied to key metabolic pathways' activities and intratumoral metabolite levels in immune cells [227] , the way by which CAF secretome could affect metabolism and immune cells function in the TME requires further investigation [228] .”
BackgroundImmunosenescence and Inflamm-Aging As Two Sides of the Same Coin: Friends or Foes?
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Metadata
- Authors
- Buck, M. D., Sowell, R. T., Kaech, S. M., & Pearce, E. L.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2017-05
- Volume
- 169
- Issue
- 4
- Pages
- 570-586
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W2611694282
- Cited by
- 1,214
- References
- 54
- FWCI
- 45.32
- Type
- journal article
- Language
- en
- Open access
- bronze
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Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
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