Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
Riaz, Nadeem, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Urba, Walter J., Sims, Jennifer S., Hodi, F. Stephen, Martín-Algarra, Salvador +17 more·2017·Cell
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Items 101–200 of 1,002
- High-throughput and single-cell T cell receptor sequencing technologiesJoy A. Pai, Ansuman T. Satpathy · 2021 · Nature Methods
- Genetic and non-genetic clonal diversity in cancer evolutionJames R. Black, Nicholas McGranahan · 2021 · Nature reviews. Cancer
- PD-1/PD-L1 Blockade: Have We Found the Key to Unleash the Antitumor Immune Response?Zijun Yidan Xu-Monette, Mingzhi Zhang, Jianyong Li, Ken H. Young · 2017 · Frontiers in Immunology
- Pan-cancer spatially resolved single-cell analysis reveals the crosstalk between cancer-associated fibroblasts and tumor microenvironmentChenxi Ma, Chengzhe Yang, Ai Fen Peng, Tianyong Sun, Xiaoli Ji, Jun Mi, Wei Li, Song Shen, Qiang Feng · 2023 · Molecular Cancer
- Transcriptional downregulation of MHC class I and melanoma de- differentiation in resistance to PD-1 inhibitionJenny Lee, Elena Shklovskaya, Su Yin Lim, Matteo Salvatore Carlino, Alexander Maxwell Menzies, Ashleigh Stewart, Bernadette Pedersen, Malama Irvine, Sara Alavi, Jean Yee Hwa Yang et al. · 2020 · Nature Communications
- Tumor aerobic glycolysis confers immune evasion through modulating sensitivity to T cell-mediated bystander killing via TNF-αLijian Wu, Yiteng Jin, Xi Zhao, Kaiyang Tang, Yaoning Zhao, Linjie Tong, Xuerong Yu, Ke Xiong, Ce Luo, Jiajun Zhu et al. · 2023 · Cell Metabolism
- Acquired cancer resistance to combination immunotherapy from transcriptional loss of class I HLAKelly Garneski Paulson, Valentin Voillet, Megan S. McAfee, Daniel S. Hunter, Felecia D. Wagener, Maurizio Perdicchio, William J. Valente, Samson Koelle, Candice D. Church, Natalie A. Vandeven et al. · 2018 · Nature Communications
- Adverse Events Following Cancer Immunotherapy: Obstacles and OpportunitiesPauken, Kristen E., Dougan, Michael, Rose, Noel R., Lichtman, Andrew H., Sharpe, Arlene H. · 2019 · Trends in Immunology
- Integrated analysis of single-cell and bulk RNA sequencing data reveals a pan-cancer stemness signature predicting immunotherapy responseZhen Zhang, Zixian Wang, Yan‐Xing Chen, Hao‐Xiang Wu, Ling Yin, Qi Zhao, Hui Luo, Zhao-Lei Zeng, Miao‐Zhen Qiu, Rui‐Hua Xu · 2022 · Genome Medicine
- CD4+ T-cell Immunity in the Peripheral Blood Correlates with Response to Anti-PD-1 TherapyKagamu, Hiroshi, Kitano, Shigehisa, Yamaguchi, Ou, Yoshimura, Kenichi, Horimoto, Katsuhisa, Kitazawa, Masashi, Fukui, Kazuhiko, Shiono, Ayako, Mouri, Atsuhito, Nishihara, Fuyumi et al. · 2020 · Cancer Immunology Research
- Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity ThresholdVredevoogd, David W., Kuilman, Thomas, Ligtenberg, Maarten A., Boshuizen, Julia, Stecker, Kelly E., de Bruijn, Beaunelle, Krijgsman, Oscar, Huang, Xinyao, Kenski, Juliana C.N., Lacroix, Ruben et al. · 2019 · Cell
- Promises and challenges of adoptive T-cell therapies for solid tumoursMatteo Morotti, Ashwag Albukhari, Abdulkhaliq Alsaadi, Mara Artibani, James D. Brenton, Stuart M. Curbishley, Tao Dong, Michael Loran Dustin, Zhiyuan Hu, Nicholas McGranahan et al. · 2021 · British Journal of Cancer
- Emerging Prospects of Exosomes for Cancer Treatment: From Conventional Therapy to ImmunotherapyGi‐Hoon Nam, Yoonjeong Choi, Gi Beom Kim, Seohyun Kim, Seong A Kim, In‐San Kim · 2020 · Advanced Materials
- TCR Repertoire Diversity of Peripheral PD-1+CD8+ T Cells Predicts Clinical Outcomes after Immunotherapy in Patients with Non–Small Cell Lung CancerJiefei Han, Jianchun Duan, Hua Bai, Yuqi Wang, Rui Wan, Xin Wang, Si Chen, Yanhua Tian, Di Wang, Kailun Fei et al. · 2019 · Cancer Immunology Research
- CXCR4 inhibition in human pancreatic and colorectal cancers induces an integrated immune responseDaniele Biasci, Martin Smoragiewicz, Claire M. Connell, Zhikai Wang, Ya Gao, James E. D. Thaventhiran, Bristi Basu, Łukasz Magiera, Timothy Isaac Johnson, Lisa Bax et al. · 2020 · Proceedings of the National Academy of Sciences
- Improved prediction of immune checkpoint blockade efficacy across multiple cancer typesDiego Chowell, Seong‐Keun Yoo, Cristina Valero, Alessandro Pastore, Chirag Krishna, Mark Lee, Douglas Robert Hoen, Hongyu Shi, Daniel W. Kelly, Neal Patel et al. · 2021 · Nature Biotechnology
- A Transcriptionally Distinct CXCL13+CD103+CD8+ T-cell Population Is Associated with B-cell Recruitment and Neoantigen Load in Human CancerHagma H. Workel, Joyce M. Lubbers, Roland R. Arnold, Thalina M. Prins, Pieter van der Vlies, Kim de Lange, Tjalling Bosse, Inge C. van Gool, Florine A. Eggink, Maartje C.A. Wouters et al. · 2019 · Cancer Immunology Research
- Determinants of anti-PD-1 response and resistance in clear cell renal cell carcinomaLewis Au, Emine Hatipoglu, Marc Robert de Massy, Kevin Litchfield, Gordon Beattie, Andrew Rowan, Désirée Schnidrig, R. Houston Thompson, Fiona Byrne, Stuart D. Horswell et al. · 2021 · Cancer Cell
- Spatial immunophenotypes predict response to anti-PD1 treatment and capture distinct paths of T cell evasion in triple negative breast cancerHammerl, Dora, Martens, John W. M., Timmermans, Mieke, Smid, Marcel, Trapman-Jansen, Anita M., Foekens, Renée, Isaeva, Olga I., Voorwerk, Leonie, Balcioglu, Hayri E., Wijers, Rebecca et al. · 2021 · Nature Communications
- Neoadjuvant therapy with immune checkpoint blockade, antiangiogenesis, and chemotherapy for locally advanced gastric cancerSong Li, Wenbin Yu, Fei Xie, Haitao Luo, Zhimin Liu, Weiwei Lv, Duan‐Bo Shi, Dexin Yu, Peng Gao, Cheng Chen et al. · 2023 · Nature Communications
- Host tissue determinants of tumour immunityHélène Salmon, Romain Remark, Sacha Gnjatic, Miriam Mérad · 2019 · Nature reviews. Cancer
- Antagonistic Inflammatory Phenotypes Dictate Tumor Fate and Response to Immune Checkpoint BlockadeEduardo Bonavita, Christian P. Bromley, Gustav Jonsson, Victoria S. Pelly, Sudhakar Sahoo, Katherine Walwyn-Brown, Sofia Mensurado, Agrin Moeini, Eimear Flanagan, Charlotte R. Bell et al. · 2020 · Immunity
- Immune gene signatures for predicting durable clinical benefit of anti-PD-1 immunotherapy in patients with non-small cell lung cancerHwang, Sohyun, Kwon, Ah-Young, Jeong, Ju-Yeon, Kim, Sewha, Kang, Haeyoun, Park, Joonsuk, Kim, Joo-Hang, Han, Ok Jin, Lim, Sun Min, An, Hee Jung · 2020 · Scientific Reports
- Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separationYu, Man, Peng, Zhengxin, Qin, Min, Liu, Yang, Wang, Jingning, Zhang, Cai, Lin, Jiaming, Dong, Tianqi, Wang, Lulu, Li, Shasha et al. · 2021 · Molecular Cell
- Assessing the interactions between radiotherapy and antitumour immunityGrassberger, Clemens, Ellsworth, Susannah G., Wilks, Moses Q., Keane, Florence K., Loeffler, Jay S. · 2019 · Nature Reviews Clinical Oncology
- Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial interim resultsChristine D. Palmer, Amy Rappaport, Matthew J. Davis, Meghan G. Hart, Ciaran D. Scallan, Sue‐Jean Hong, Leonid Gitlin, Lauren D. Kraemer, Sonia Kounlavouth, Aaron Yang et al. · 2022 · Nature Medicine
- Mechanisms of immune activation and regulation: lessons from melanomaShelly Kalaora, Adi Nagler, Jennifer Ann Wargo, Yardena Samuels · 2022 · Nature reviews. Cancer
- Cancer immunotherapy: broadening the scope of targetable tumoursJitske van den Bulk, Els M.E. Verdegaal, Noel F.C.C. de Miranda · 2018 · Open Biology
- Tumor mutational burden standardization initiatives: Recommendations for consistent tumor mutational burden assessment in clinical samples to guide immunotherapy treatment decisionsAlbrecht Stenzinger, Jeffrey D. Allen, J. Maas, Mark D. Stewart, Diana M. Merino, Madison M. Wempe, Manfred Dietel · 2019 · Genes Chromosomes and Cancer
- Tumour mutational burden as a biomarker for immunotherapy: Current data and emerging conceptsJean-David Fumet, Caroline Truntzer, Mark M. Yarchoan, François Ghiringhelli · 2020 · European Journal of Cancer
- In vivo CRISPR screens reveal the landscape of immune evasion pathways across cancerDubrot, Juan, Du, Peter P., Lane-Reticker, Sarah Kate, Kessler, Emily A., Muscato, Audrey J., Mehta, Arnav, Freeman, Samuel S., Allen, Peter M., Olander, Kira E., Ockerman, Kyle M. et al. · 2022 · Nature Immunology
- FDA-Approved and Emerging Next Generation Predictive Biomarkers for Immune Checkpoint Inhibitors in Cancer PatientsWang, Ye, Tong, Zhuang, Zhang, Wenhua, Zhang, Weizhen, Buzdin, Anton, Mu, Xiaofeng, Yan, Qing, Zhao, Xiaowen, Chang, Hui-Hua, Duhon, Mark et al. · 2021 · Frontiers in Oncology
- 9p21 loss confers a cold tumor immune microenvironment and primary resistance to immune checkpoint therapyGuangchun Han, Guoliang Yang, Dapeng Hao, Yang Lü, Kyaw Zin Thein, Benjamin Scott S Simpson, Jianfeng Chen, Ryan Sun, Omar Alhalabi, Ruiping Wang et al. · 2021 · Nature Communications
- An RNA toolbox for cancer immunotherapyPastor, Fernando, Berraondo, Pedro, Etxeberria, Iñaki, Frederick, Josh, Sahin, Ugur, Gilboa, Eli, Melero, Ignacio · 2018 · Nature Reviews Drug Discovery
- Drug Resistance in Non-Small Cell Lung Cancer: A Potential for NOTCH Targeting?Venus Sosa Iglesias, Lorena Giuranno, Ludwig Jerome Dubois, Jan Theys, Marc Vooijs · 2018 · Frontiers in Oncology
- Multiomics Prediction of Response Rates to Therapies to Inhibit Programmed Cell Death 1 and Programmed Cell Death 1 Ligand 1Joo Sang Lee, Eytan Ruppin · 2019 · JAMA Oncology
- m6A regulator-based methylation modification patterns characterized by distinct tumor microenvironment immune profiles in colon cancerWei Chong, Liang Shang, Jin Liu, Zhen Fang, Fengying Du, Hao Wu, Liu Yang, Zhe Wang, Yang Chen, Shengtao Jia et al. · 2020 · Theranostics
- Metabolomic adaptations and correlates of survival to immune checkpoint blockadeLi, Haoxin, Bullock, Kevin, Gurjao, Carino, Braun, David, Shukla, Sachet A., Bossé, Dominick, Lalani, Aly-Khan A., Gopal, Shuba, Jin, Chelsea, Horak, Christine et al. · 2019 · Nature Communications
- Mutations in BRCA1 and BRCA2 differentially affect the tumor microenvironment and response to checkpoint blockade immunotherapySamstein, Robert M., Krishna, Chirag, Ma, Xiaoxiao, Pei, Xin, Lee, Ken-Wing, Makarov, Vladimir, Kuo, Fengshen, Chung, Jonathan, Srivastava, Raghvendra M., Purohit, Tanaya A. et al. · 2020 · Nature Cancer
- PD-1/PD-L1 Targeting in Breast Cancer: The First Clinical Evidences are Emerging—A Literature ReviewGabrielle Planes-Laine, Philippe Rochigneux, François Bertucci, Anne-Sophie Chrétien, Patrice Viens, Renaud Sabatier, Anthony Gonçalvès · 2019 · Cancers
- Network-based machine learning approach to predict immunotherapy response in cancer patientsKong, JungHo, Ha, Doyeon, Lee, Juhun, Kim, Inhae, Park, Minhyuk, Im, Sin-Hyeog, Shin, Kunyoo, Kim, Sanguk · 2022 · Nature Communications
- TGFβ-blockade uncovers stromal plasticity in tumors by revealing the existence of a subset of interferon-licensed fibroblastsGrauel, Angelo L., Nguyen, Beverly, Ruddy, David, Laszewski, Tyler, Schwartz, Stephanie, Chang, Jonathan, Chen, Julie, Piquet, Michelle, Pelletier, Marc, Yan, Zheng et al. · 2020 · Nature Communications
- Biomarkers for Clinical Benefit of Immune Checkpoint Inhibitor Treatment—A Review From the Melanoma Perspective and BeyondKristina Buder‐Bakhaya, Jessica C. Hassel · 2018 · Frontiers in Immunology
- Melanoma subtypes: genomic profiles, prognostic molecular markers and therapeutic possibilitiesRoy Rabbie, Peter M. Ferguson, Christian Molina‐Aguilar, David J. Adams, Carla Daniela Robles‐Espinoza · 2018 · The Journal of Pathology
- Methionine deficiency facilitates antitumour immunity by altering m 6 A methylation of immune checkpoint transcriptsTing Li, Yue‐Tao Tan, Yan‐Xing Chen, Xiaojun Zheng, Wen Wang, Kun Lun Liao, Hai‐Yu Mo, Junzhong Lin, Wei Yang, Hai‐long Piao et al. · 2022 · Gut
- Sensitization to immune checkpoint blockade through activation of a STAT1/NK axis in the tumor microenvironmentRachael M. Zemek, Emma de Jong, Wee Loong Chin, Iona S. Schuster, Vanessa S. Fear, Thomas H. Casey, Cath Forbes, Sarah Dart, Connull Leslie, Ayham Zaitouny et al. · 2019 · Science Translational Medicine
- Current Perspectives in Cancer ImmunotherapyTheodoulakis Christofi, Stavroula Baritaki, Luca Falzone, Massimo Libra, Apostolos Zaravinos · 2019 · Cancers
- Spatiotemporal single-cell analysis decodes cellular dynamics underlying different responses to immunotherapy in colorectal cancerYuqing Chen, Dongfang Wang, Yingjie Li, Qi Lu, Wen Si, Yufei Bo, Xueyan Chen, Zhaochen Ye, Hongtao Fan, Baolin Liu et al. · 2024 · Cancer Cell
- A gene expression signature of TREM2hi macrophages and γδ T cells predicts immunotherapy responseDonghai Xiong, Yian Wang, Ming You · 2020 · Nature Communications
- Comprehensive Genomic Profiling Identifies Novel Genetic Predictors of Response to Anti–PD-(L)1 Therapies in Non–Small Cell Lung CancerWenfeng Fang, Yuxiang Ma, Jiani C. Yin, Shaodong Hong, Huaqiang Zhou, Ao Wang, Fufeng Wang, Hua Bao, Xue Wu, Yunpeng Yang et al. · 2019 · Clinical Cancer Research
- Intratumoral CXCL13 + CD8 + T cell infiltration determines poor clinical outcomes and immunoevasive contexture in patients with clear cell renal cell carcinomaSiyuan Dai, Han Zeng, Zhaopei Liu, Kaifeng Jin, Wenbin Jiang, Zewei Wang, Zhiyuan Lin, Ying Xiong, Jiajun Wang, Yuan Chang et al. · 2021 · Journal for ImmunoTherapy of Cancer
- Tumor-derived prostaglandin E2 programs cDC1 dysfunction to impair intratumoral orchestration of anti-cancer T cell responsesFelix Bayerl, Philippa Meiser, Sainitin Donakonda, Anna Hirschberger, Sebastian B. Lacher, Anna‐Marie Pedde, Chris D. Hermann, Anais Elewaut, Moritz A. Knolle, Lukas Ramsauer et al. · 2023 · Immunity
- In vivo CRISPR screens identify the E3 ligase Cop1 as a modulator of macrophage infiltration and cancer immunotherapy targetXiaoqing Wang, Collin J. Tokheim, Shengqing Stan Gu, Binbin Wang, Qin Tang, Yihao Li, Nicole C. Traugh, Zexian Zeng, Yi Zhang, Ziyi Li et al. · 2021 · Cell
- Genomic heterogeneity in bladder cancer: challenges and possible solutions to improve outcomesJoshua J. Meeks, Hikmat A Al‐Ahmadie, Bishoy M. Faltas, John Arthur Taylor, Thomas W. Flaig, David J. DeGraff, Emil Christensen, Benjamin Leeland Woolbright, David James McConkey, Lars Dyrskjøt · 2020 · Nature Reviews Urology
- Predictive biomarkers of immunotherapy response with pharmacological applications in solid tumorsSzonja Kovacs, János Tibor Fekete, Balázs Győrffy · 2023 · Acta Pharmacologica Sinica
- The Immune Subtypes and Landscape of Squamous Cell CarcinomaBailiang Li, Yi Cui, Dhanya K. Nambiar, John B. Sunwoo, Ruijiang Li · 2019 · Clinical Cancer Research
- LIMIT is an immunogenic lncRNA in cancer immunity and immunotherapyGaopeng Li, Ilona Kryczek, Jutaek Nam, Xiong Li, Shasha Li, Jing Li, Shuang Wei, Sara Grove, Linda Vatan, Jiajia Zhou et al. · 2021 · Nature Cell Biology
- Resistance mechanisms to immune checkpoint inhibitors: updated insightsBesan H. Al-Saafeen, Bassam R. Ali, Eyad Elkord · 2025 · Molecular Cancer
- The T cell receptor repertoire of tumor infiltrating T cells is predictive and prognostic for cancer survivalSara Valpione, Piyushkumar A. Mundra, Elena Galvani, Luca Giovanni Campana, Paul C. Lorigan, Francesco De Rosa, Avinash Gupta, John Weightman, Sarah Catherine Mills, Nathalie S. Dhomen et al. · 2021 · Nature Communications
- Predictive biomarkers of response for immune checkpoint inhibitors in non–small-cell lung cancerArsela Prelaj, Rebecca Yin Tay, Roberto Ferrara, Nathalie Chaput, Benjamin Besse, Raffaele Califano · 2018 · European Journal of Cancer
- Epigenetic driver mutations in ARID1A shape cancer immune phenotype and immunotherapyJing Li, Weichao Wang, Yajia Zhang, Marcin P. Cieslik, Jipeng Guo, Mengyao Tan, Michael D. Green, Weimin Wang, Heng Lin, Wei Li et al. · 2020 · Journal of Clinical Investigation
- Myeloid antigen-presenting cell niches sustain antitumor T cells and license PD-1 blockade via CD28 costimulationJaikumar Duraiswamy, Riccardo Turrini, Aspram Minasyan, David Barras, Isaac Crespo, Alizée J Grimm, Julia Casado, Raphaël Genolet, Fabrizio Benedetti, Alexandre M. Wicky et al. · 2021 · Cancer Cell
- Beta2-microglobulin(B2M) in cancer immunotherapies: Biological function, resistance and remedyHanbing Wang, Baorui Liu, Jia Wei · 2021 · Cancer Letters
- Tumor-infiltrating mast cells are associated with resistance to anti-PD-1 therapyRajasekharan Somasundaram, Thomas Connelly, Robin Choi, Hyeree Choi, Anastasia Samarkina, Ling Li, Elizabeth Gregorio, Yeqing Chen, Rohit Thakur, Mohamed Abdel‐Mohsen et al. · 2021 · Nature Communications
- Targeting tumor-derived NLRP3 reduces melanoma progression by limiting MDSCs expansionIsak W. Tengesdal, D. R. Menon, D. G. Osborne, C. Neff, Nicholas E. Powers, F. Gamboni, A. Mauro, A. D'Alessandro, D. Stefanoni, M. Henen et al. · 2021 · Proceedings of the National Academy of Sciences of the United States of America
- Blockade of LAG-3 and PD-1 leads to co-expression of cytotoxic and exhaustion gene modules in CD8+ T cells to promote antitumor immunityAnthony Richard Cillo, Carly Cardello, Feng Shan, Lilit Karapetyan, Sheryl R. Kunning, Cindy Sander, Elizabeth A. Rush, Arivarasan D. Karunamurthy, Ryan Campbell Massa, Anjali Rohatgi et al. · 2024 · Cell
- Melanoma: What do all the mutations mean?Elizabeth J. Davis, Douglas Buckner Johnson, Jeffrey Alan Sosman, Sunandana Chandra · 2018 · Cancer
- Association of LRP1B Mutation With Tumor Mutation Burden and Outcomes in Melanoma and Non-small Cell Lung Cancer Patients Treated With Immune Check-Point BlockadesHao Chen, Wei Chong, Qian Wu, Yueliang Yao, Min Mao, Xin Wang · 2019 · Frontiers in Immunology
- Defined tumor antigen-specific T cells potentiate personalized TCR-T cell therapy and prediction of immunotherapy responseJingjing He, Xinxin Xiong, Han Yang, Dandan Li, Xuefei Liu, Shuo Li, Shuangye Liao, Siyu Chen, Xizhi Wen, Kuai Yu et al. · 2022 · Cell Research
- Combined MEK and STAT3 Inhibition Uncovers Stromal Plasticity by Enriching for Cancer-Associated Fibroblasts With Mesenchymal Stem Cell-Like Features to Overcome Immunotherapy Resistance in Pancreatic CancerJashodeep Datta, Xizi Dai, Anna Bianchi, Iago De Castro Silva, Siddharth Mehra, Vanessa T. Garrido, Purushottam Lamichhane, Samara P. Singh, Zhiqun Zhou, Austin R. Dosch et al. · 2021 · Gastroenterology
- Myeloid-derived suppressor cells in cancer: therapeutic targets to overcome tumor immune evasionJunli Lu, Yiming Luo, Dean Rao, Tiantian Wang, Zhen Lei, Xiaoping Chen, Bixiang Zhang, Yiwei Li, Bi‐Feng Liu, Limin Xia et al. · 2024 · Experimental Hematology and Oncology
- T-cell CX3CR1 expression as a dynamic blood-based biomarker of response to immune checkpoint inhibitorsTakayoshi Yamauchi, Toshifumi Hoki, Takaaki Oba, Vaibhav Jain, Hongbin Chen, Kristopher M. Attwood, Sebastiano Battaglia, Saby George, Gurkamal S. Chatta, Igor J. Puzanov et al. · 2021 · Nature Communications
- CAMOIP: a web server for comprehensive analysis on multi-omics of immunotherapy in pan-cancerLin, Anqi, Qi, Chang, Wei, Ting, Li, Mengyao, Cheng, Quan, Liu, Zaoqu, Luo, Peng, Zhang, Jian · 2022 · Briefings in Bioinformatics
- Understanding and overcoming the resistance of cancer to PD-1/PD-L1 blockadeAmy L. Shergold, Rhona Millar, Robert J. B. Nibbs · 2019 · Pharmacological Research
- Ablation of the endoplasmic reticulum stress kinase PERK induces paraptosis and type I interferon to promote anti-tumor T cell responsesJay K. Mandula, Shiun Chang, Eslam T. Mohamed, Rachel Jimenez, Rosa A. Sierra-Mondragon, Darwin Chang, Alyssa Obermayer, Carlos Moran Segura, Satyajit Das, Julio Angel Vázquez-Martínez et al. · 2022 · Cancer Cell
- Cancer immunotherapies transition endothelial cells into HEVs that generate TCF1+ T lymphocyte niches through a feed-forward loopYichao Hua, Gerlanda Vella, Florian Rambow, Elizabeth Allen, Asier Antoranz, Marie Duhamel, Akira Takeda, Sirpa Jalkanen, Steffie Junius, Ann Smeets et al. · 2022 · Cancer Cell
- PIRD: pan immune repertoire databaseZhang, Wei, Wang, Longlong, Liu, Ke, Wei, Xiaofeng, Yang, Kai, Du, Wensi, Wang, Shiyu, Guo, Nannan, Ma, Chuanchuan, Luo, Lihua et al. · 2020 · Bioinformatics
- Complex inter-relationship of body mass index, gender and serum creatinine on survival: exploring the obesity paradox in melanoma patients treated with checkpoint inhibitionGirish S. Naik, Sushrut S. Waikar, Alistair E. W. Johnson, Elizabeth Iannotti Buchbinder, Rizwan Haq, Frank Stephen Hodi, Jonathan Daniel Schoenfeld, Patrick Alexander Ott · 2019 · Journal for ImmunoTherapy of Cancer
- Pan-cancer association of HLA gene expression with cancer prognosis and immunotherapy efficacyEvelien Schaafsma, Chloe M. Fugle, Xiaofeng Wang, Chao Cheng · 2021 · British Journal of Cancer
- Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancerNitin Roper, Moises J. Velez, Alberto Chiappori, Yoo Sun Kim, Jun Stephen Wei, Sivasish Sindiri, Nobuyuki Takahashi, Deborah A. Mulford, Suresh Kumar, Kris Ylaya et al. · 2021 · Nature Communications
- Genomics of response to immune checkpoint therapies for cancer: implications for precision medicineConway, Jake R., Kofman, Eric, Mo, Shirley S., Elmarakeby, Haitham, Van Allen, Eliezer · 2018 · Genome Medicine
- Multiomic profiling of checkpoint inhibitor-treated melanoma: Identifying predictors of response and resistance, and markers of biological discordanceFelicity Newell, Inês Pires da Silva, Peter A. Johansson, Alexander Maxwell Menzies, James S. Wilmott, Venkateswar Addala, Matteo Salvatore Carlino, Helen Rizos, Kátia Nones, Jarem J. Edwards et al. · 2021 · Cancer Cell
- Dissecting the immunosuppressive tumor microenvironments in Glioblastoma-on-a-Chip for optimized PD-1 immunotherapyXin Cui, Chao Ma, Varshini Vasudevaraja, Jonathan Serrano, Jie Tong, Yansong Peng, Michael DeLorenzo, Guomiao Shen, Joshua D. Frenster, Renee‐Tyler T. Morales et al. · 2020 · eLife
- Update on Tumor Neoantigens and Their Utility: Why It Is Good to Be DifferentChung‐Han Lee, Roman Yelensky, Karin U. Jooss, Timothy An-thy Chan · 2018 · Trends in Immunology
- Midkine rewires the melanoma microenvironment toward a tolerogenic and immune-resistant stateDaniela Cerezo‐Wallis, Marta Contreras-Alcalde, Kevin Troulé, Xavier Catena, Cynthia Mucientes, Tonantzin G. Calvo, Estela Cañón, Cristina Tejedo, Paula Comune Pennacchi, Sabrina A. Hogan et al. · 2020 · Nature Medicine
- Stanniocalcin 1 is a phagocytosis checkpoint driving tumor immune resistanceHeng Lin, Ilona Kryczek, Shasha Li, Michael D. Green, Alicia Ali, Reema Hamasha, Shuang Wei, Linda Vatan, Wojciech Szeliga, Sara Grove et al. · 2021 · Cancer Cell
- PAK4 inhibition improves PD-1 blockade immunotherapyGabriel Abril-Rodríguez, Davis Yuri Torrejon, Wei Liu, Jesse Meir Zaretsky, Theodore Scott Nowicki, Jennifer Tsoi, Cristina Puig-Saus, Ignacio Baselga-Carretero, Egmidio Medina, Michael J. Quist et al. · 2019 · Nature Cancer
- Titin mutation associated with responsiveness to checkpoint blockades in solid tumorsQingzhu Jia, Jun Wang, Ning He, Ji He, Bo Zhu · 2019 · JCI Insight
- Single-cell transcriptome analysis reveals TOX as a promoting factor for T cell exhaustion and a predictor for anti-PD-1 responses in human cancerKyung-Soo Kim, Seyeon Park, Sung Yong Park, Gamin Kim, Su Myeong Park, Jae-Won Cho, Dahee Kim, Young Min Park, Yoon Woo Koh, Hye Ryun Kim et al. · 2020 · Genome Medicine
- Synthetic lethality-mediated precision oncology via the tumor transcriptomeJoo Sang Lee, Nishanth Ulhas Nair, Gal Dinstag, Lesley M. Chapman, Youngmin Chung, Kun Wang, Sanju Sinha, Hongui Cha, Dasol Kim, Alexander V. Schperberg et al. · 2021 · Cell
- Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome ActivationMercedes Segovia, Sofía Russo, Mathías Jeldres, Yamil Damian Mahmoud, Valentina Perez, Maite Duhalde Vega, Pierre Charnet, Matthieu Rousset, Sabina Victoria, Florencia Veigas et al. · 2019 · Cancer Cell
- Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapyGaopeng Li, Jae Eun Choi, Ilona Kryczek, Yilun Sun, Peng Liao, Shasha Li, Shuang Wei, Sara Grove, Linda Vatan, Reagan Nelson et al. · 2023 · Cancer Cell
- Overcoming Genetically Based Resistance Mechanisms to PD-1 BlockadeTorrejon, Davis Y., Abril-Rodriguez, Gabriel, Champhekar, Ameya S., Tsoi, Jennifer, Campbell, Katie M., Kalbasi, Anusha, Parisi, Giulia, Zaretsky, Jesse M., Garcia-Diaz, Angel, Puig-Saus, Cristina et al. · 2020 · Cancer Discovery
- Trial watch: Peptide-based vaccines in anticancer therapyLucillia Bezu, Oliver Kepp, Giulia Cerrato, Jonathan G. Pol, Jitka Palich Fucikova, Radek Špíšek, Laurence Zitvogel, Guido Kroemer, Lorenzo Galluzzi · 2018 · OncoImmunology
- Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy ResistanceOrgaz, Jose L., Crosas-Molist, Eva, Sadok, Amine, Perdrix-Rosell, Anna, Maiques, Oscar, Rodriguez-Hernandez, Irene, Monger, Jo, Mele, Silvia, Georgouli, Mirella, Bridgeman, Victoria et al. · 2020 · Cancer Cell
- Mechanisms underlying low-clinical responses to PD-1/PD-L1 blocking antibodies in immunotherapy of cancer: a key role of exosomal PD-L1Zi Yin, Min Yu, Tingting Ma, Chuanzhao Zhang, Shanzhou� Huang, Mohammad Reza Karimzadeh, Amir Abbas Momtazi‐Borojeni, Sheng Chen · 2021 · Journal for ImmunoTherapy of Cancer
- The role of RNA methylation in tumor immunity and its potential in immunotherapyYan Li, Haoer Jin, Qingling Li, Liangrong Shi, Yitao Mao, Luqing Zhao · 2024 · Molecular Cancer
- Understanding the mechanisms of resistance to CAR T-cell therapy in malignancies.Cheng, Jiali, Zhao, Lei, Zhang, Yuanyuan, Qin, Yun, Guan, Yuqi, Zhang, Tong, Liu, Chaohong, Zhou, Jianfeng · 2019 · Frontiers in Oncology
- Neoantigen Dissimilarity to the Self-Proteome Predicts Immunogenicity and Response to Immune Checkpoint BlockadeLee P. Richman, Robert H. Vonderheide, Andrew J. Rech · 2019 · Cell Systems
- DeepHLApan: A Deep Learning Approach for Neoantigen Prediction Considering Both HLA-Peptide Binding and ImmunogenicityJingcheng Wu, Wenzhe Wang, Jiucheng Zhang, Binbin Zhou, Wenyi Zhao, Zhixi Su, Xun Gu, Jian Wu, Zhan Mei Zhou, Shuqing Chen · 2019 · Frontiers in Immunology