Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab
Riaz, Nadeem, Havel, Jonathan J., Makarov, Vladimir, Desrichard, Alexis, Urba, Walter J., Sims, Jennifer S., Hodi, F. Stephen, Martín-Algarra, Salvador +17 more·2017·Cell
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- A pyroptosis-related lncRNA signature predicts prognosis and immune microenvironment in head and neck squamous cell carcinomaWenying Zhu, Zhipeng Ye, Ling Chen, Haifeng Liang, Qian Cai · 2021 · International Immunopharmacology
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- TCR sequencing analysis of cancer tissues and tumor draining lymph nodes in colorectal cancer patientsTatsuo Matsuda, Eisaku Miyauchi, Yu-Wen Hsu, Satoshi Nagayama, Kazuma Kiyotani, Makda Getachew Zewde, Jae‐Hyun Park, Taigo Kato, Makiko Harada, Shimpei Matsui et al. · 2019 · OncoImmunology
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- CAR-T cell combination therapies in hematologic malignanciesDelian Zhou, Xiaojian Zhu, Yi Qun Xiao · 2024 · Experimental Hematology and Oncology
- Intratumoral mycobiome heterogeneity influences the tumor microenvironment and immunotherapy outcomes in renal cell carcinomaWeiming Mou, Zhixing Deng, Lingxuan Zhu, Aimin Jiang, Anqi Lin, Liling Xu, Gengwen Deng, Hongsen Huang, Zeji Guo, Bo Zhu et al. · 2025 · Science Advances
- Melanoma-Secreted Lysosomes Trigger Monocyte-Derived Dendritic Cell Apoptosis and Limit Cancer ImmunotherapyNadine Santana-Magal, Leen Farhat-Younis, Amit Gutwillig, Annette Gleiberman, Diana Rasoulouniriana, Lior Tal, Dvir Netanely, Ron Shamir A, Rachel Blau, Meora Feinmesser et al. · 2020 · Cancer Research
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- Association of clock-like mutational signature with immune checkpoint inhibitor outcome in patients with melanoma and NSCLCWei Chong, Zhe Wang, Liang Shang, Shengtao Jia, Jin Liu, Zhen Fang, Fengying Du, Hao Wu, Yang Liu, Yang Chen et al. · 2020 · Molecular Therapy — Nucleic Acids
- Neoadjuvant pazopanib and molecular analysis of tissue response in renal cell carcinomaChristopher G. Wood, James E. Ferguson, Joel S. Parker, Dominic T. Moore, Jennifer G. Whisenant, Susan J. Maygarden, Eric Wallen, William Y. Kim, Mathew I. Milowsky, Kathryn Eby Beckermann et al. · 2020 · JCI Insight
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- Resistance against anti-CD19 and anti-BCMA CAR T cells: Recent advances and coping strategiesPınar Ataca Atilla, Erden Atilla · 2022 · Translational Oncology
- Deep learning identifies a T-cell exhaustion-dependent transcriptional signature for predicting clinical outcomes and response to immune checkpoint blockadeZicheng Zhang, Hongyan Chen, Dongxue Yan, Lu Chen, Jie Sun, Meng Zhou · 2023 · Oncogenesis
- DNAJA2 deficiency activates cGAS-STING pathway via the induction of aberrant mitosis and chromosome instabilityYaping Huang, Changzheng Lu, Hanzhi Wang, Liya Gu, Yang‐Xin Fu, Guo‐Min Li · 2023 · Nature Communications
- Predicting patient outcomes after treatment with immune checkpoint blockade: A review of biomarkers derived from diverse data modalitiesYang Liu, Jennifer Altreuter, Sudheshna Bodapati, Simona Cristea, Cheryl J. Wong, Catherine J. Wu, Franziska Michor · 2023 · Cell Genomics
- Long‐term follow up of nivolumab in previously untreated Japanese patients with advanced or recurrent malignant melanomaNaoya Yamazaki, Yoshio Kiyohara, Hisashi Uhara, Jiro Uehara, Yasuhiro Fujisawa, Tatsuya Takenouchi, Masaki Otsuka, Hiroshi Uchi, Hironobu Ihn, Masahiro Hatsumichi et al. · 2019 · Cancer Science
- The impact of CTLA-4 blockade and interferon-α on clonality of T-cell repertoire in the tumor microenvironment and peripheral blood of metastatic melanoma patientsArjun Khunger, Julie A. Rytlewski, Paul Fields, Erik C. Yusko, Ahmad A. Tarhini · 2019 · OncoImmunology
- Stroma remodeling and reduced cell division define durable response to PD-1 blockade in melanomaElena Galvani, Piyushkumar A. Mundra, Sara Valpione, Pablo Luis García-Martínez, Matthew Smith, Jonathan Greenall, Rohit Thakur, Beth Ann Helmink, Miles Cameron Andrews, Louis Boon et al. · 2020 · Nature Communications
- Advances in theranostic biomarkers for tumor immunotherapyAudrey Bellesœur, Nouritza Torossian, Sebastián Amigorena, Emanuela Romano · 2020 · Current Opinion in Chemical Biology
- Targeted and immunotherapies in BRAF mutant melanoma: where we stand and what to expectXue Li Bai, Keith T. Flaherty · 2020 · British Journal of Dermatology
- Defining best practices for tissue procurement in immuno-oncology clinical trials: consensus statement from the Society for Immunotherapy of Cancer Surgery CommitteeBrian Gastman, Piyush Kumar Agarwal, Adam Berger, Genevieve Marie Boland, Stephen Broderick, Lisa Helene Butterfield, David R. Byrd, Peter Edward Fecci, Robert Louis Ferris, Yuman Fong et al. · 2020 · Journal for ImmunoTherapy of Cancer
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- Polycomb repressor complex 2 suppresses interferon-responsive MHC-II expression in melanoma cells and is associated with anti-PD-1 resistanceJamaal L. James, Brandie C. Taylor, Margaret L. Axelrod, Xiaopeng Sun, Lindsey N. Guerin, Paula I. González Ericsson, Yu Wang, Violeta M. Sanchez, Catherine C. Fahey, Melinda E. Sanders et al. · 2023 · Journal for ImmunoTherapy of Cancer
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- An iron-rich subset of macrophages promotes tumor growth through a Bach1-Ednrb axisIan Wesley Folkert, William A. Molina Arocho, Tsun Ki Jerrick To, Samir Devalaraja, Irene S. Molina, Jason Shoush, Hesham Mohei, Li Zhai, Md. Naushad Akhtar, Veena Kochat et al. · 2024 · The Journal of Experimental Medicine
- Pretrained transformers applied to clinical studies improve predictions of treatment efficacy and associated biomarkers2025
- Circulating CD8+ T-cell repertoires reveal the biological characteristics of tumors and clinical responses to chemotherapy in breast cancer patientsKai-Rong Lin, Danmei Pang, Yabin Jin, Qian Hu, Ying-ming Pan, Jin‐Huan Cui, Xiangping Chen, Yin-Xin Lin, Xiaofan Mao, Haibo Duan et al. · 2018 · Cancer Immunology Immunotherapy
- Acquired resistance to immunotherapy in MMR-D pancreatic cancerZishuo Ian Hu, Matthew David Hellmann, Jedd D. Wolchok, Monika Vyas, Jinru Shia, Zsofia Kinga Stadler, Luis Alberto Diaz, Eileen Mary O'Reilly · 2018 · Journal for ImmunoTherapy of Cancer
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- SITC cancer immunotherapy resource document: a compass in the land of biomarker discoverySiwen Hu‐Lieskovan, Srabani Bhaumik, Kavita M. Dhodapkar, Jean‐Charles Grivel, Sumati V. Gupta, Brent Allen Hanks, Sylvia Janetzki, Thomas O. Kleen, Yoshinobu Koguchi, Amanda W. Lund et al. · 2020 · Journal for ImmunoTherapy of Cancer
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- Immune and stromal scoring system associated with tumor microenvironment and prognosis: a gene-based multi-cancer analysisZihang Zeng, Jiali Li, Jian‐Guo Zhang, Yangyi Li, Xingyu Liu, Jiarui Chen, Zhengrong Huang, Qiuji Wu, Yan Qing Gong, Conghua Xie · 2021 · Journal of Translational Medicine
- Replication stress response defects are associated with response to immune checkpoint blockade in nonhypermutated cancersDaniel James McGrail, Patrick Glen Pilie, Hui Dai, Truong Lam, Yulong Liang, Leonie Voorwerk, Marleen Kok, Xiang H.-F. Zhang, Jeffrey M. Rosen, Amy B. Heimberger et al. · 2021 · Science Translational Medicine
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- Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanomaAndrew Patterson, Noam Auslander · 2022 · Nature Communications
- Cuproptosis-related modification patterns depict the tumor microenvironment, precision immunotherapy, and prognosis of kidney renal clear cell carcinomaZhiyong Cai, You'e He, Zheng-Zheng Yu, Jiao Hu, Zicheng Xiao, Xiongbing Zu, Zhenghao Li, Huihuang Li · 2022 · Frontiers in Immunology
- MHC II immunogenicity shapes the neoepitope landscape in human tumorsJeong Yeon Kim, Hongui Cha, Kyeonghui Kim, Changhwan Sung, Jinhyeon An, Hyoeun Bang, Hyungjoo Kim, Jin Ok Yang, Suhwan Chang, Incheol Shin et al. · 2023 · Nature Genetics
- CD200 + cytotoxic T lymphocytes in the tumor microenvironment are crucial for efficacious anti–PD-1/PD-L1 therapyXinxin Wang, Haoran Zha, Wei Wu, Ting Yuan, Shuanglong Xie, Zheng Jin, Haixia Long, Fei Yang, Zhongyu Wang, Anmei Zhang et al. · 2023 · Science Translational Medicine
- An adverse tumor-protective effect of IDO1 inhibitionJuliana C.N. Kenski, Xinyao Huang, David W. Vredevoogd, Beaunelle de Bruijn, Joleen J.H. Traets, Sofia Ibáñez‐Molero, Sebastiaan M. Schieven, Alex v. Vliet, Oscar Krijgsman, Thomas Kuilman et al. · 2023 · Cell Reports Medicine
- Approaches for single-cell RNA sequencing across tissues and cell typesPooja Sant, Karsten Rippe, Jan‐Philipp Mallm · 2023 · Transcription
- Enhancing Cancer Chemo‐Immunotherapy: Innovative Approaches for Overcoming Immunosuppression by Functional NanomaterialsJingjing Wang, Li Li, Zhi Ping Xu · 2023 · Small Methods
- Robust identification of perturbed cell types in single-cell RNA-seq dataPhillip B. Nicol, Danielle Paulson, Gege Qian, X. Shirley Liu, Rafael A. Irizarry, Avinash D Sahu · 2024 · Nature Communications
- Big Data Approaches for Modeling Response and Resistance to Cancer DrugsPeng Jiang, William R. Sellers, X. Shirley Liu · 2018 · Annual Review of Biomedical Data Science
- Design and conduct of early clinical studies of immunotherapy agent combinations: recommendations from the task force on Methodology for the Development of Innovative Cancer TherapiesMartin Smoragiewicz, Jan Bogaerts, Emiliano Calvo, Aurélien Marabelle, A. Perrone, Lesley Seymour, A. Shalabi, Lillian L. Siu, Josep M. Tabernero, Giuseppe Giaccone et al. · 2018 · Annals of Oncology
- The “-OMICS” facet of melanoma: Heterogeneity of genomic, proteomic and metabolomic biomarkersDouglas MacArthur Donnelly, Phyu P. Aung, George Jour · 2019 · Seminars in Cancer Biology
- NSCLC Biomarkers to Predict Response to Immunotherapy with Checkpoint Inhibitors (ICI): From the Cells to In Vivo ImagesVirginia Liberini, Annapaola Mariniello, Luisella Righi, Martina Capozza, Marco Donatello Delcuratolo, Enzo Terreno, Mohsen Farsad, Marco Volante, Silvia Novello, Désirèe Deandreis · 2021 · Cancers
- Urinary detection of early responses to checkpoint blockade and of resistance to it via protease-cleaved antibody-conjugated sensorsQuoc D. Mac, Anirudh Sivakumar, Hathaichanok Phuengkham, Congmin Xu, James R. Bowen, Fang‐Yi Su, Samuel Z. Stentz, Hyoungjun Sim, Adrian M. Harris, Tonia T. Li et al. · 2022 · Nature Biomedical Engineering
- Albendazole induces immunotherapy response by facilitating ubiquitin-mediated PD-L1 degradationLin Zhu, Xinwei Kuang, Guanxiong Zhang, Long Liang, Dandan Liu, Bin Hu, Zuozhong Xie, Hui Li, Hong Liu, Mao Ye et al. · 2022 · Journal for ImmunoTherapy of Cancer
- Concepts Collide: Genomic, Immune, and Microbial Influences on the Tumor Microenvironment and Response to Cancer TherapyMiles Cameron Andrews, Alexandre Reuben, Vancheswaran Gopalakrishnan, Jennifer Ann Wargo · 2018 · Frontiers in Immunology
- Biomechanics of T Cell Dysfunctions in Chronic DiseasesSachith D. Gunasinghe, Newton G. Peres, Jesse Goyette, Katharina Gaus · 2021 · Frontiers in Immunology
- Acarbose enhances the efficacy of immunotherapy against solid tumours by modulating the gut microbiotaShilong Zhang, Xin Wang, Qing-Qing Cai, Chen Chen, Zheng-Yan Zhang, Yayun Xu, Mengxuan Yang, Qing-An Jia, Yan Wang, Zhi-ming Wang · 2024 · Nature Metabolism
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- Cancer Evolution during ImmunotherapyMiles Cameron Andrews, Jennifer Ann Wargo · 2017 · Cell
- TCR Repertoire Analysis Reveals Mobilization of Novel CD8+ T Cell Clones Into the Cancer-Immunity Cycle Following Anti-CD4 Antibody AdministrationHiroyasu Aoki, Satoshi Ueha, Shigeyuki Shichino, Haru Ogiwara, Shin-ichi Hashimoto, Kazuhiro Kakimi, Satoru Ito, Kouji Matsushima · 2019 · Frontiers in Immunology
- WISP1 is associated to advanced disease, EMT and an inflamed tumor microenvironment in multiple solid tumorsPierre-Olivier Gaudreau, Sylvie Clairefond, Caleb A. Class, Pierre-Luc Boulay, Pavel Chrobák, Bertrand Allard, Féryel Azzi, Sandra Pommey, Kim-Anh Do, Fred Saad C et al. · 2019 · OncoImmunology
- Differential gene expression of tumor-infiltrating CD8 + T cells in advanced versus early-stage colorectal cancer and identification of a gene signature of poor prognosisReem Saleh, Varun Sasidharan Nair, Salman M. Toor, Rowaida Ziad Taha, Khaled Murshed, Mahmood Al‐Dhaheri, Mahwish Khawar, Mahir Abdulla Petkar, Mohamed Abu Nada, Fares Al‐Ejeh et al. · 2020 · Journal for ImmunoTherapy of Cancer
- DGKA Mediates Resistance to PD-1 BlockadeLingyi Fu, Sen Li, Weiwei Xiao, Kuai Yu, Shuo Li, Sujing Yuan, Jianfei Shen, Xingjun Dong, Ziqian Fang, Jianeng Zhang et al. · 2021 · Cancer Immunology Research
- Circulating cell‐free messenger RNA enables non‐invasive pan‐tumour monitoring of melanoma therapy independent of the mutational genotypeLea Jessica Albrecht, A. Hoewner, Klaus Griewank, Smiths Lueong, Nils v. Neuhoff, Péter Horn, Antje Sucker, Annette Paschen, Elisabeth Livingstone, Selma Ugurel et al. · 2022 · Clinical and Translational Medicine
- Cancer-associated fibroblasts-derived exosomes from chemoresistant patients regulate cisplatin resistance and angiogenesis by delivering VEGFA in colorectal cancerYuanyuan Shi, Hua Zhu, Hang Jiang, Hongqin Yue, Fang Yuan, Fu‐Sheng Wang · 2022 · Anti-Cancer Drugs
- Immunotherapy for Metastatic Non-Small Cell Lung Cancer: Therapeutic Advances and BiomarkersMarco Russano, Giulia La Cava, Alessio Cortellini, Fabrizio Citarella, Alessandro Galletti, Giuseppina Rita Di Fazio, Valentina Santo, Leonardo Brunetti, Alessia Vendittelli, Iacopo Fioroni et al. · 2023 · Current Oncology
- The role of IFN-γ-signalling in response to immune checkpoint blockade therapyChun Wai Wong, Yang Huang, Adam F. L. Hurlstone · 2023 · Essays in Biochemistry
- Insight into immune profile associated with vitiligo onset and anti-tumoral response in melanoma patients receiving anti-PD-1 immunotherapyMaria Luigia Carbone, Alessia Capone, Marika Guercio, Sofia Reddel, Domenico Alessandro Silvestris, Daniela Lulli, Carmela Ramondino, Daniele Peluso, Concetta Quintarelli, Elisabetta Volpe et al. · 2023 · Frontiers in Immunology
- Batf3+ DCs and the 4-1BB/4-1BBL axis are required at the effector phase in the tumor microenvironment for PD-1/PD-L1 blockade efficacyAndrea Ziblat, Brendan L. Horton, Emily F. Higgs, Ken Hatogai, Anna Martinez, Jason W. Shapiro, Danny EC Kim, Yuanyuan Zha, Randy F. Sweis, Thomas Frank Gajewski · 2024 · Cell Reports
- Non-invasive profiling of the tumour microenvironment with spatial ecotypesWubing Zhang, Erin L. Brown, Abul Usmani, Noah J. Earland, Minji Kang, Chibuzor Olelewe, Anushka Viswanathan, Pradeep S. Chauhan, Chloé Beate Steen, Hyun Soo Jeon et al. · 2026 · Nature
- Detecting Immune Response to Therapies Targeting PDL1 and BRAF by Using Ferumoxytol MRI and Macrin in Anaplastic Thyroid CancerThomas S.C. Ng, Viswanath Gunda, Ran Li, Mark Prytyskach, Yoshiko Iwamoto, Rainer H. Köhler, Sareh Parangi, Ralph Weissleder, Miles Aaron Miller · 2020 · Radiology
- Systematic Assessment of Transcriptomic Biomarkers for Immune Checkpoint Blockade Response in Cancer ImmunotherapyShangqin Sun, Liwen Xu, Xinxin Zhang, Lin Pang, Zhilin Long, Chunyu Deng, Jiali Zhu, Shuting Zhou, Linyun Wan, Bo Pang et al. · 2021 · Cancers