Tumor and Microenvironment Evolution during Immunotherapy with Nivolumab

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Ovarian Cancer Immunotherapy and Personalized Medicine

Morand, S. M., Devanaboyina, M., Staats, H., Stanbery, L., & Nemunaitis, J. J. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22126532 · Cited by 383 · see citing works

Immunogenic neoantigens derived from gene fusions stimulate T cell responses

Yang, W., Lee, K.-W., Srivastava, R. M., Kuo, F., Krishna, C., Chowell, D., Makarov, V., Hoen, D. R., Dalin, M. G., Wexler, L. H., et al. (2019) · Nature Medicine · doi:10.1038/s41591-019-0434-2 · Cited by 374 · see citing works

B cells sustain inflammation and predict response to immune checkpoint blockade in human melanoma

Griss, J., Bauer, W. M., Wagner, C., Simon, M., Chen, M., Grabmeier‐Pfistershammer, K., Maurer‐Granofszky, M., Roka, F., Penz, T., Bock, C., et al. (2019) · Nature Communications · doi:10.1038/s41467-019-12160-2 · Cited by 373 · see citing works

Tumors exploit FTO-mediated regulation of glycolytic metabolism to evade immune surveillance

Liu, Y., Liang, G., Xu, H., Dong, W., Dong, Z., Qiu, Z., Zhang, Z., Li, F., Huang, Y., Li, Y., et al. (2021) · Cell Metabolism · doi:10.1016/j.cmet.2021.04.001 · Cited by 370 · see citing works

Exploring immunotherapy in colorectal cancer

Weng, J., Li, S., Zhu, Z., Liu, Q., Zhang, R., Yang, Y., & Li, X. (2022) · Journal of Hematology &amp; Oncology · doi:10.1186/s13045-022-01294-4 · Cited by 355 · see citing works

Pan-cancer deconvolution of tumour composition using DNA methylation

Chakravarthy, A., Furness, A., Joshi, K., Ghorani, E., Ford, K., Ward, M. J., King, E. V., Lechner, M., Marafioti, T., Quezada, S. A., et al. (2018) · Nature Communications · doi:10.1038/s41467-018-05570-1 · Cited by 327 · see citing works

Expression profile of immune checkpoint genes and their roles in predicting immunotherapy response

Hu, F., Liu, C., Liu, L., Zhang, Q., & Guo, A. (2020) · Briefings in Bioinformatics · doi:10.1093/bib/bbaa176 · Cited by 354 · see citing works

Atlas of clinically distinct cell states and ecosystems across human solid tumors

Luca, B. A., Steen, C. B., Matusiak, M., Azizi, A., Varma, S., Zhu, C., Przybył, J., Espín-Pérez, A., Diehn, M., Alizadeh, A. A., et al. (2021) · Cell · doi:10.1016/j.cell.2021.09.014 · Cited by 344 · see citing works

Implementing TMB measurement in clinical practice: considerations on assay requirements

Büttner, R., Longshore, J. W., López‐Ríos, F., Merkelbach‐Bruse, S., Normanno, N., Rouleau, É., & Penault-Llorca, F. M. (2019) · ESMO Open · doi:10.1136/esmoopen-2018-000442 · Cited by 342 · see citing works

Neoadjuvant relatlimab and nivolumab in resectable melanoma

Amaria, R. N., Postow, M. A., Burton, E. M., Tetzlaff, M. T., Ross, M. I., Torres-Cabala, C. A., Glitza, I. C., Duan, F., Milton, D. R., BUSAM, K. J., et al. (2022) · Nature · doi:10.1038/s41586-022-05368-8 · Cited by 347 · see citing works

TRUST4: immune repertoire reconstruction from bulk and single-cell RNA-seq data

Song, L., Cohen, D., Ouyang, Z., Cao, Y., Hu, X. S., & Liu, X. S. (2021) · Nature Methods · doi:10.1038/s41592-021-01142-2 · Cited by 334 · see citing works

Immuno-subtyping of breast cancer reveals distinct myeloid cell profiles and immunotherapy resistance mechanisms

Kim, I. S., Gao, Y., Welte, T., Wang, H., Liu, J., Janghorban, M., Sheng, K., Niu, Y., Goldstein, A., Zhao, N., et al. (2019) · Nature Cell Biology · doi:10.1038/s41556-019-0373-7 · Cited by 334 · see citing works

Exaggerated false positives by popular differential expression methods when analyzing human population samples

Li, Y., Ge, X., Peng, F., Li, W., & Li, J. J. (2022) · Genome Biology · doi:10.1186/s13059-022-02648-4 · Cited by 303 · see citing works

TYRO3 induces anti–PD-1/PD-L1 therapy resistance by limiting innate immunity and tumoral ferroptosis

Jiang, Z., Lim, S., Yan, M., Hsu, J. L., Yao, J., Wei, Y., Chang, S.-S., Yamaguchi, H., Lee, H., Ke, B., et al. (2021) · Journal of Clinical Investigation · doi:10.1172/jci139434 · Cited by 329 · see citing works

Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence

Harel, M., Ortenberg, R., Varanasi, S. K., Mangalhara, K. C., Mardamshina, M., Markovits, E., Baruch, E. N., Tripple, V., Arama-Chayoth, M., Greenberg, E., et al. (2019) · Cell · doi:10.1016/j.cell.2019.08.012 · Cited by 323 · see citing works

Cancer-cell-derived GABA promotes β-catenin-mediated tumour growth and immunosuppression

Huang, D., Wang, Y., Thompson, J. W., Yin, T., Alexander, P. B., Qin, D., Mudgal, P., Wu, H., Liang, Y., Tan, L., et al. (2022) · Nature Cell Biology · doi:10.1038/s41556-021-00820-9 · Cited by 320 · see citing works

Dynamics of Tumor and Immune Responses during Immune Checkpoint Blockade in Non–Small Cell Lung Cancer

Anagnostou, V., Forde, P. M., White, J. R., Niknafs, N., Hruban, C., Naidoo, J., Marrone, K. A., Sivakumar, I. K. A., Bruhm, D. C., Rosner, S., et al. (2018) · Cancer Research · doi:10.1158/0008-5472.can-18-1127 · Cited by 319 · see citing works

T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma

Lozano, A. X., Chaudhuri, A. A., Nene, A., Bacchiocchi, A., Earland, N. J., Vesely, M. D., Usmani, A., Turner, B. E., Steen, C. B., Luca, B. A., et al. (2022) · Nature Medicine · doi:10.1038/s41591-021-01623-z · Cited by 314 · see citing works

Immunobiology and immunotherapy of HCC: spotlight on innate and innate-like immune cells

Ruf, B., Heinrich, B., & Greten, T. (2020) · Cellular & Molecular Immunology · doi:10.1038/s41423-020-00572-w · Cited by 282 · see citing works

Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy

Chowell, D., Krishna, C., Pierini, F., Makarov, V., Rizvi, N. A., Kuo, F., Morris, L. G. T., Riaz, N., Lenz, T. L., & Chan, T. A.-T. (2019) · Nature Medicine · doi:10.1038/s41591-019-0639-4 · Cited by 309 · see citing works

Defining clinically useful biomarkers of immune checkpoint inhibitors in solid tumours

Holder, A. M., Dedeilia, A., Sierra-Davidson, K., Cohen, S., Liu, D., Parikh, A. R., & Boland, G. M. (2024) · Nature reviews. Cancer · doi:10.1038/s41568-024-00705-7 · Cited by 313 · see citing works

Heterogeneity of the tumor immune microenvironment and its clinical relevance

Jia, Q., Wang, A., Yuan, Y.-X., Zhu, B., & Long, H.-X. (2022) · Experimental Hematology & Oncology · doi:10.1186/s40164-022-00277-y · Cited by 236 · see citing works

Self-Supplied Tumor Oxygenation through Separated Liposomal Delivery of H2O2 and Catalase for Enhanced Radio-Immunotherapy of Cancer

Song, X., Xu, J., Liang, C., Chao, Y., Jin, Q., Wang, C., Chen, M., & Liu, Z. (2018) · Nano Letters · doi:10.1021/acs.nanolett.8b02720 · Cited by 299 · see citing works

Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

Lee, J. S., Adler, L. N., Karathia, H., Carmel, N. N., Rabinovich, S., Auslander, N., Keshet, R., Stettner, N., Silberman, A., Agemy, L., et al. (2018) · Cell · doi:10.1016/j.cell.2018.07.019 · Cited by 297 · see citing works

Abstract 2988: Immunogenomic analyses of tumor cells and microenvironment in patients with advanced melanoma before and after treatment with nivolumab

Chan, T. A.-T., Riaz, N., Havel, J. J., Makarov, V., Desrichard, A., Sims, J. S., Hodi, F. S., Martín‐Algarra, S., Sharfman, W. H., Bhatia, S., et al. (2017) · Cancer Research · doi:10.1158/1538-7445.am2017-2988

Abstract 1125: Neoantigen immunogenicity landscapes and evolution of tumor ecosystems during immunotherapy with nivolumab

Alban, T. J., Riaz, N., Parthasarathy, P. B., Makarov, V., Kendall, S., Yoo, S., Shah, R., Weinhold, N., Srivastava, R. M., Ma, X., et al. (2023) · Cancer Research · doi:10.1158/1538-7445.am2023-1125 · Cited by 1 · see citing works

Tumor control

Visan, I. (2017) · Nature Immunology · doi:10.1038/ni.3878

Association of Tumor Microenvironment T-cell Repertoire and Mutational Load with Clinical Outcome after Sequential Checkpoint Blockade in Melanoma

Yusko, E. C., Vignali, M., Wilson, R. K., Mardis, E. R., Hodi, F. S., Horak, C. E., Chang, H., Woods, D. M., Robins, H. S., & Weber, J. S. (2019) · Cancer Immunology Research · doi:10.1158/2326-6066.cir-18-0226 · Cited by 59 · see citing works

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