A Method for the Acute and Rapid Degradation of Endogenous Proteins

Cited by (533)

Items 101–200 of 533

  1. HIV-1 is dependent on its immature lattice to recruit IP6 for mature capsid assembly
    Nadine Renner, Alex B. Kleinpeter, Donna L. Mallery, Anna Albecka, K. M. Rifat Faysal, Till Böcking, Adolfo Saiardi, Eric O. Freed, Leo C. James · 2023 · Nature Structural & Molecular Biology
  2. Multi‐Omics Analysis Reveals Translational Landscapes and Regulations in Mouse and Human Oocyte Aging
    Jiana Huang, Peigen Chen, Lei Jia, Tingting Li, Xing Yang, Qiqi Liang, Yanyan Zeng, Jiawen Liu, Taibao Wu, Wenqi Hu et al. · 2023 · Advanced Science
  3. Type I IFN drives unconventional IL-1β secretion in lupus monocytes
    Simone Caielli, Preetha Balasubramanian, Juan F. Rodríguez-Alcázar, Uthra Balaji, Lauren A. Robinson, Zurong Wan, Jeanine M. Baisch, Cynthia Smitherman, Lynnette Walters, Paola R. Sparagana et al. · 2024 · Immunity
  4. Degradation of endogenous proteins and generation of a null-like phenotype in zebrafish using Trim-Away technology
    Xiao Chen, Mi Liu, Hongyan Lou, Yiyi Lu, Mengtao Zhou, Rongying Ou, Yunsheng Xu, Kai‐Fu Tang · 2019 · Genome biology
  5. Emerging targeted protein degradation tools for innovative drug discovery: From classical PROTACs to the novel and beyond
    Yue Zhong, Fanglian Chi, Hanyu Wu, Yunxiao Liu, Zhancheng Xie, Wenlong Huang, Wei Shi, Hai Qian · 2022 · European Journal of Medicinal Chemistry
  6. Intracellular complement: Evidence, definitions, controversies, and solutions
    Ben C. King, Anna Marie Blom · 2022 · Immunological Reviews
  7. Tunable light and drug induced depletion of target proteins
    Wen Deng, Jack A. Bates, Hai Wei, Michael D. Bartoschek, Barbara Conradt, Heinrich Leonhardt · 2020 · Nature Communications
  8. Advances in peptide-mediated cytosolic delivery of proteins
    Macarena Sánchez‐Navarro · 2021 · Advanced Drug Delivery Reviews
  9. A genetically encoded toolkit of functionalized nanobodies against fluorescent proteins for visualizing and manipulating intracellular signalling
    David L. Prole, Colin W. Taylor · 2019 · BMC Biology
  10. Leveraging aptamers for targeted protein degradation
    Zhihao Yang, Qiuxiang Pang, Jun Zhou, Chenghao Xuan, Songbo Xie · 2023 · Trends in Pharmacological Sciences
  11. Launching the C-HPP neXt-CP50 Pilot Project for Functional Characterization of Identified Proteins with No Known Function
    Young‐Ki Paik, Lydie Lane, Takeshi Kawamura, Yu‐Ju Chen, Je‐Yoel Cho, Joshua LaBaer, Jong Shin Yoo, Gilberto B. Domont, Fernando José Corrales, Gilbert S. Omenn et al. · 2018 · Journal of Proteome Research
  12. A Cell-Permeant Nanobody-Based Degrader That Induces Fetal Hemoglobin
    Fangfang Shen, Ge Zheng, Mekedlawit T. Setegne, Karin Tenglin, Manizheh Izadi, Henry T.H. Xie, Liting Zhai, Stuart H. Orkin, Laura M. K. Dassama · 2022 · ACS Central Science
  13. A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases
    L. Kiss, Jingwei Zeng, Claire F. Dickson, Donna L. Mallery, Ji‐Chun Yang, Stephen H. McLaughlin, Andreas Boland, David Neuhaus, Leo C. James · 2019 · Nature Communications
  14. Acute disruption of the synaptic vesicle membrane protein synaptotagmin 1 using knockoff in mouse hippocampal neurons
    Jason Vevea, Edwin R. Chapman · 2020 · eLife
  15. Analysis of Serological Biomarkers of SARS-CoV-2 Infection in Convalescent Samples From Severe, Moderate and Mild COVID-19 Cases
    Javier Castillo‐Olivares, David A. Wells, Matteo Ferrari, Andrew C. Y. Chan, Peter Smith, Angalee Nadesalingam, Minna Paloniemi, George Carnell, Luis Ohlendorf, Diego M. Cantoni et al. · 2021 · Frontiers in Immunology
  16. Imaging of native transcription factors and histone phosphorylation at high resolution in live cells
    Sascha Conic, Dominique Desplancq, Alexia Ferrand, Véronique Fischer, Vincent Heyer, Bernardo Reina‐San‐Martin, Julien Pontabry, Mustapha Oulad‐Abdelghani, Kishore Babu N., Graham Daniel Wright et al. · 2018 · The Journal of Cell Biology
  17. Nanotechnology-based siRNA delivery strategies for metastatic colorectal cancer therapy
    Ana Rita Sousa, Ana Vanessa Oliveira, María José Oliveira, Bruno Filipe Carmelino Cardoso Sarmento · 2019 · International Journal of Pharmaceutics
  18. Nasal tau immunotherapy clears intracellular tau pathology and improves cognitive functions in aged tauopathy mice
    Sagar Gaikwad, Nicha Puangmalai, Minal Sonawane, Mauro Montalbano, Rachel Price, Malini S. Iyer, Anamika Ray, Sandra Moreno, Rakez Kayed · 2024 · Science Translational Medicine
  19. Resurgent and Gating Pore Currents Induced by De Novo SCN2A Epilepsy Mutations
    Emily R. Mason, Fenfen Wu, Reesha R. Patel, Yucheng Xiao, Stephen C. Cannon, Theodore Cummins · 2019 · eNeuro
  20. RanGTP and importin β regulate meiosis I spindle assembly and function in mouse oocytes
    Dávid Drutovič, Xing Duan, Rong Li, Petr Kaláb, Petr Solc · 2019 · The EMBO Journal
  21. Symmetry breaking in hydrodynamic forces drives meiotic spindle rotation in mammalian oocytes
    Haiyang Wang, Yizeng Li, Jing Yang, Xing Duan, Petr Kaláb, Sean X. Sun, Rong Li · 2020 · Science Advances
  22. RNA scaffolds the Golgi ribbon by forming condensates with GM130
    Yijun Zhang, Joachim Seemann · 2024 · Nature Cell Biology
  23. Function and Regulation of Phase-Separated Biological Condensates
    Xiaohan Li, Pavithra Lakshminarasimhan Chavali, Rita Pancsa, Sreenivas Chavali, M. Madan Babu · 2018 · Biochemistry
  24. The Role of Antibodies and Their Receptors in Protection Against Ordered Protein Assembly in Neurodegeneration
    Taxiarchis Katsinelos, Benjamin J. Tuck, Aamir S. Mukadam, William A. McEwan · 2019 · Frontiers in Immunology
  25. Gold Nanoparticle-Mediated Photoporation Enables Delivery of Macromolecules over a Wide Range of Molecular Weights in Human CD4+ T Cells
    Laurens Raes, Clarissa Van Hecke, Julie Michiels, Stephan Stremersch, Juan C. Fraire, Toon Brans, Ranhua Xiong, Stefaan C. De Smedt, Linos Vandekerckhove, Koen Raemdonck et al. · 2019 · Crystals
  26. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome
    Wenliang Zhu, Boya Zhang, Mengqi Li, Fan Mo, Ting‐Wei Mi, Yihui Wu, Zhao‐Qian Teng, Qi Zhou, Wei Li, Baoyang Hu · 2019 · Nature Communications
  27. A Regeneration Toolkit
    Mayssa H. Mokalled, Kenneth D. Poss · 2018 · Developmental Cell
  28. Loss of CENPF leads to developmental failure in mouse embryos
    Cheng-Jie Zhou, Xingyue Wang, Zhe Han, Donghui Wang, Yuzhen Ma, Cheng‐Guang Liang · 2019 · Cell Cycle
  29. Maternal factors regulating preimplantation development in mice
    Di Wu, Jurrien Dean · 2019 · Current topics in developmental biology/Current Topics in Developmental Biology
  30. Nanobodies Right in the Middle: Intrabodies as Toolbox to Visualize and Modulate Antigens in the Living Cell
    Teresa R. Wagner, Ulrich Rothbauer · 2020 · Biomolecules
  31. Beyond canonical PROTAC: biological targeted protein degradation (bioTPD)
    Huifang Wang, Runhua Zhou, Fushan Xu, Kongjun Yang, Liuhai Zheng, Pan Zhao, Guangwei Shi, Lingyun Dai, Chengchao Xu, Le Yu et al. · 2023 · Biomaterials Research
  32. Antibody and DNA sensing pathways converge to activate the inflammasome during primary human macrophage infection
    Larisa I. Labzin, Maria Bottermann, Pablo Rodríguez-Silvestre, Stian Foss, Jan Terje Andersen, Marina Vaysburd, Dean Clift, Leo C. James · 2019 · The EMBO Journal
  33. Mechanisms of minor pole–mediated spindle bipolarization in human oocytes
    Tianyu Wu, Yuxi Luo, Meiling Zhang, Biaobang Chen, Xingzhu Du, Hao Gu, Siyuan Xie, Zhiqi Pan, Ran Yu, Ruiqi Hai et al. · 2024 · Science
  34. A Targeted Protein Degradation Cell-Based Screening for Nanobodies Selective toward the Cellular RHOB GTP-Bound Conformation
    Nicolas Béry, Laura Keller, Marjorie Soulié, Rémi Gence, Anne-Laure Iscache, Julia Cherier, Stéphanie Cabantous, Olivier Sordet, Isabelle Lajoie‐Mazenc, J.D. Pédelacq et al. · 2019 · Cell chemical biology
  35. Emerging Roles of Tripartite Motif-Containing Family Proteins (TRIMs) in Eliminating Misfolded Proteins
    Litian Zhang, Lukman Olalekan Afolabi, Xiaochun Wan, Yang Li, Liang Chen · 2020 · Frontiers in Cell and Developmental Biology
  36. Recent advances in targeted protein degraders as potential therapeutic agents
    Na Yang, Bo Kong, Zhaohong Zhu, Fei Huang, Liliang Zhang, Tao Lu, Yadong Chen, Yanmin Zhang, Yulei Jiang · 2023 · Molecular Diversity
  37. Actin-driven chromosome clustering facilitates fast and complete chromosome capture in mammalian oocytes
    Katarina Harasimov, Julia Uraji, Eike Urs Mönnich, Zuzana Holubcová, Kay T. Elder, Martyn L Blayney, Melina Schuh · 2023 · Nature Cell Biology
  38. UbiREAD deciphers proteasomal degradation code of homotypic and branched K48 and K63 ubiquitin chains
    L. Kiss, Leo C. James, Brenda Arlene Schulman · 2025 · Molecular Cell
  39. Applying Antibodies Inside Cells: Principles and Recent Advances in Neurobiology, Virology and Oncology
    Congcong Zhang, Rina Ötjengerdes, Julian Roewe, Rebeca Mejı́as, Andrea L. J. Marschall · 2020 · BioDrugs
  40. Monoclonal full-length antibody against TAR DNA binding protein 43 reduces related proteinopathy in neurons
    Silvia Pozzi, Philippe Codron, Geneviève Soucy, Laurence Renaud, Pierre Cordeau, Kallol Dutta, Christine Bareil, Jean‐Pierre Julien · 2020 · JCI Insight
  41. PROTACs, molecular glues and bifunctionals from bench to bedside: Unlocking the clinical potential of catalytic drugs
    María Maneiro, Elena De Vita, Daniel Conole, Cyrille S. Kounde, Qisi Zhang, Edward W. Tate · 2021 · Progress in medicinal chemistry
  42. Targeted Protein Degradation Technology and Nanomedicine: Powerful Allies against Cancer
    Jia‐Yi Lin, Haijun Liu, Ye Wu, Jin‐Mei Jin, Yudong Zhou, Hong Zhang, Dale G. Nagle, Hongzhuan Chen, Weidong Zhang, Xin Luan · 2023 · Small
  43. E3 ubiquitin ligase TRIM21 targets TIF1γ to regulate β-catenin signaling in glioblastoma
    YanLan Li, Lingbo Bao, Hong Zheng, Mingying Geng, TianYi Chen, Xiaoyan Dai, Xiao He, Lujie Yang, Chengyi Mao, Yuan Qiu et al. · 2023 · Theranostics
  44. Intracellular delivery of anti-BCR/ABL antibody by PLGA nanoparticles suppresses the oncogenesis of chronic myeloid leukemia cells
    Guoyun Jiang, Zhenglan Huang, Ying Yuan, Kun Tao, Wenli Feng · 2021 · Journal of Hematology & Oncology
  45. NAT10 Maintains OGA mRNA Stability Through ac4C Modification in Regulating Oocyte Maturation
    Jiayu Lin, Yuting Xiang, Jiana Huang, Haitao Zeng, Yanyan Zeng, Jiawen Liu, Taibao Wu, Qiqi Liang, Xiaoyan Liang, Jingjie Li et al. · 2022 · Frontiers in Endocrinology
  46. Targeting glucocorticoid receptor signaling pathway for treatment of stress-related brain disorders
    Tansu Göver, Michał Ślęzak · 2024 · Pharmacological Reports
  47. Synthetic Control of Protein Degradation during Cell Proliferation and Developmental Processes
    Jonathan Trauth, Johannes Scheffer, Sophia Hasenjäger, Christof Taxis · 2019 · ACS Omega
  48. Targeted Protein Degradation through Cytosolic Delivery of Monobody Binders Using Bacterial Toxins
    Nadine Eliane Schmit, Katyayanee Neopane, Oliver D. Hantschel · 2019 · ACS Chemical Biology
  49. Extremely rapid and reversible optogenetic perturbation of nuclear proteins in living embryos
    Anna C. Kögler, Yacine Kherdjemil, Katharina Bender, Adam H. Rabinowitz, Raquel Marco-Ferreres, Eileen E. M. Furlong · 2021 · Developmental Cell
  50. Cytoskeletal form and function in mammalian oocytes and zygotes
    Sam Dunkley, Kathleen Scheffler, Binyam Mogessie · 2022 · Current Opinion in Cell Biology
  51. Sculpting ion channel functional expression with engineered ubiquitin ligases
    Scott A. Kanner, Travis J. Morgenstern, Henry M. Colecraft · 2017 · eLife
  52. Gene regulation technologies for gene and cell therapy
    Gabriel L. Butterfield, Samuel J. Reisman, Nahid Iglesias, Charles A. Gersbach · 2025 · Molecular Therapy
  53. Nanogel‐Facilitated Protein Intracellular Specific Degradation through Trim‐Away
    Binglin Sui, Mingming Wang, Chen Cheng, Quanguang Zhang, Jiajia Zhang, Daping Fan, Peisheng Xu · 2021 · Advanced Functional Materials
  54. Actin limits egg aneuploidies associated with female reproductive aging
    Sam Dunkley, Binyam Mogessie · 2023 · Science Advances
  55. Nanocarriers for intracellular delivery of proteins in biomedical applications: strategies and recent advances
    Chuanda Zhu, Jing Mu, Ling Liang · 2024 · Journal of Nanobiotechnology
  56. Enhancing mitophagy as a therapeutic approach for neurodegenerative diseases
    Yahyah Aman, Brent James Ryan, Silje Bøen Torsetnes, Anne‐Brita Knapskog, Leiv Otto Watne, William A. McEwan, Evandro Fei Fang · 2020 · International review of neurobiology
  57. Potent TRIM21 and complement-dependent intracellular antiviral immunity requires the IgG3 hinge
    Stian Foss, Alexandra Jonsson, Maria Bottermann, Ruth Watkinson, Heidrun Elisabeth Lode, Martin B. McAdam, Terje Einar Michaelsen, Inger Sandlie, Leo C. James, Jan Terje Andersen · 2022 · Science Immunology
  58. An Inside Job: Applications of Intracellular Single Domain Antibodies
    Eline Soetens, Marlies Ballegeer, Xavier Saelens · 2020 · Biomolecules
  59. Retrotransposon renaissance in early embryos
    Youjia Guo, Ten D. Li, Andrew J. Modzelewski, Haruhiko Siomi · 2023 · Trends in Genetics
  60. 30 years of nanobodies – an ongoing success story of small binders in biological research
    Desiree Isabella Frecot, Theresa Fröhlich, Ulrich Rothbauer · 2023 · Journal of Cell Science
  61. Changes in DNA repair compartments and cohesin loss promote DNA damage accumulation in aged oocytes
    Ninadini Sharma, Giovanni Coticchio, Andrea Borini, Kiku-e K. Tachibana, Kim Nasmyth, Melina Schuh · 2024 · Current Biology
  62. Antibodies targeting the Crimean-Congo Hemorrhagic Fever Virus nucleoprotein protect via TRIM21
    Shanna S. Leventhal, Thomas C. Bisom, Dean Clift, Deepashri Rao, Kimberly D. Meade-White, Carl Shaia, Justin Murray, Evan A. Mihalakakos, Troy C. Hinkley, Steven James Reynolds et al. · 2024 · Nature Communications
  63. Reduced ATP-dependent proteolysis of functional proteins during nutrient limitation speeds the return of microbes to a growth state
    Jinki Yeom, Eduardo A. Groisman · 2021 · Science Signaling
  64. Trim-Away ubiquitinates and degrades lysine-less and N-terminally acetylated substrates
    L. Kiss, Tyler Rhinesmith, Jakub Lupták, Claire F. Dickson, Jonas Weidenhausen, Shannon Smyly, Ji‐Chun Yang, Sarah Maslen, Irmgard Sinning, David Neuhaus et al. · 2023 · Nature Communications
  65. TRIM21-dependent target protein ubiquitination mediates cell-free Trim-Away
    Tycho E.T. Mevissen, Anisa V. Prasad, Johannes C. Walter · 2023 · Cell Reports
  66. Satellite DNA shapes dictate pericentromere packaging in female meiosis
    Damian Dudka, Jennine M. Dawicki-McKenna, Xueqi Sun, Keagan Beeravolu, Takashi Akera, Michael A. Lampson, Ben E. Black · 2025 · Nature
  67. Protein-Based Degraders: From Chemical Biology Tools to Neo-Therapeutics
    Lisha Ou, Mekedlawit T. Setegne, Jeandele Elliot, Fangfang Shen, Laura M. K. Dassama · 2025 · Chemical Reviews
  68. Deprotection of centromeric cohesin at meiosis II requires APC/C activity but not kinetochore tension
    Valentina Mengoli, Katarzyna Jonak, Oleksii Lyzak, Mahdi Lamb, Lisa Lister, Chris Lodge, Julie Rojas, Ievgeniia Zagoriy, Mary Herbert, Wolfgang Zachariae · 2021 · The EMBO Journal
  69. Morphogenesis of the human preimplantation embryo: bringing mechanics to the clinics
    Julie Firmin, Jean‐Léon Maître · 2021 · Seminars in Cell and Developmental Biology
  70. Targeted protein degradation using intracellular antibodies and its application to neurodegenerative disease
    Jonathan Benn, Aamir S. Mukadam, William A. McEwan · 2021 · Seminars in Cell and Developmental Biology
  71. The molecular mechanisms that drive intracellular neutralization by the antibody-receptor and RING E3 ligase TRIM21
    L. Kiss, Leo C. James · 2021 · Seminars in Cell and Developmental Biology
  72. Biologics-based degraders — an expanding toolkit for targeted-protein degradation
    Derek VanDyke, Jonathan D. Taylor, Kyle J. Kaeo, James Hunt, Jamie B. Spangler · 2022 · Current Opinion in Biotechnology
  73. CENP-F-dependent DRP1 function regulates APC/C activity during oocyte meiosis I
    Chengjie Zhou, Xingyue Wang, Yanhua Dong, Donghui Wang, Zhe Han, Xiao-Jie Zhang, Qing‐Yuan Sun, John Carroll, Cheng‐Guang Liang · 2022 · Nature Communications
  74. Characterizing vulnerable brain areas and circuits in mouse models of autism: Towards understanding pathogenesis and new therapeutic approaches
    Kelvin K. Hui, Yuta Katayama, Keiichi I. Nakayama, Jun Nomura, Takeshi Sakurai · 2018 · Neuroscience & Biobehavioral Reviews
  75. SNAP23 is required for constitutive and regulated exocytosis in mouse oocytes†
    Lisa M. Mehlmann, Tracy F. Uliasz, Katie M. Lowther · 2019 · Biology of Reproduction
  76. Distinct patterns of RNA polymerase II and transcriptional elongation characterize mammalian genome activation
    Ken‐ichiro Abe, Tamás Schauer, Maria‐Elena Torres‐Padilla · 2022 · Cell Reports
  77. Auxin-Inducible Degron System: An Efficient Protein Degradation Tool to Study Protein Function
    Kundurthi Phanindhar, Rakesh K. Mishra · 2023 · BioTechniques
  78. Ubiquitin E3 ligases assisted technologies in protein degradation: Sharing pathways in neurodegenerative disorders and cancer
    Aastha Kaushik, Somya Parashar, Rashmi K. Ambasta, Pravir Kumar · 2024 · Ageing Research Reviews
  79. A pan-KRAS degrader for the treatment of KRAS-mutant cancers
    Jie Yang, Qiao-Li Wang, Guannan Wang, Jia-Cong Ye, Zi-Qian Li, Jing-Yun Wang, Zhaohui Liang, Shuxin Li, Cong Sun, Wenting Liao et al. · 2024 · Cell Discovery
  80. Nanobodies – Little helpers unravelling intracellular signaling
    Teresa R. Wagner, Ulrich Rothbauer · 2021 · Free Radical Biology and Medicine
  81. Actin organizes chromosomes and microtubules to ensure mitotic fidelity in the preimplantation embryo
    Blake Hernandez, Piotr Tetlak, Ana Domingo-Muelas, Hiroki Akizawa, Robin M. Skory, Goli Ardestani, Maté Biro, Xiaolei Liu, Stéphanie Bissière, Denny Sakkas et al. · 2025 · Science
  82. Transforming nanobodies into high-precision tools for protein function analysis
    Jan Gettemans, Brian De Dobbelaer · 2020 · American Journal of Physiology-Cell Physiology
  83. Photopharmacology of Proteolysis-Targeting Chimeras: A New Frontier for Drug Discovery
    Shenxin Zeng, Hongjie Zhang, Zhengrong Shen, Wenhai Huang · 2021 · Frontiers in Chemistry
  84. Sensitive and Quantitative Detection of MHC-I Displayed Neoepitopes Using a Semiautomated Workflow and TOMAHAQ Mass Spectrometry
    Samuel B. Pollock, Christopher M. Rose, Martine Darwish, Romain Bouziat, Lélia Delamarre, Craig Blanchette, Jennie Rebecca Lill · 2021 · Molecular & Cellular Proteomics
  85. A programmable targeted protein-degradation platform for versatile applications in mammalian cells and mice
    Xiaoding Ma, Jianli Yin, Longliang Qiao, Hang Wan, Xingwan Liu, Yang Zhou, Jiali Wu, Lingxue Niu, Min Wu, Xinyi Wang et al. · 2024 · Molecular Cell
  86. Targeted protein degradation in CNS disorders: a promising route to novel therapeutics?
    Sandra Kuemper, Andrew G. Cairns, Kristian Birchall, Zhi Yao, Jonathan M. Large · 2024 · Frontiers in Molecular Neuroscience
  87. The Potential of Proteolytic Chimeras as Pharmacological Tools and Therapeutic Agents
    Bernat Coll-Martínez, Antonio Delgado, Bernat Crosas · 2020 · Molecules
  88. A functional assay for serum detection of antibodies against SARS‐CoV‐2 nucleoprotein
    Anna Albecka, Dean Clift, Marina Vaysburd, Tyler Rhinesmith, Sarah Caddy, David Mordechai Favara, Helen Baxendale, Leo C. James · 2021 · The EMBO Journal
  89. Evolution of nanobodies specific for BCL11A
    Maolu Yin, Manizheh Izadi, Karin Tenglin, Thibault Viennet, Liting Zhai, Ge Zheng, Haribabu Arthanari, Laura M. K. Dassama, Stuart H. Orkin · 2023 · Proceedings of the National Academy of Sciences
  90. Acute inactivation of retromer and ESCPE-1 leads to time-resolved defects in endosomal cargo sorting
    Evans, Ashley J., Daly, James L., Anuar, Anis N. K., Simonetti, Boris, Cullen, Peter J. · 2020 · Journal of Cell Science
  91. Staudinger Reaction-Responsive Coacervates for Cytosolic Antibody Delivery and TRIM21-Mediated Protein Degradation
    Yishu Bao, Zhiyi Xu, Kai Cheng, Xiaojing Li, Fangke Chen, Dingdong Yuan, Fang Zhang, Audrey Run-Yu, Xiangze Zeng, Yuan‐Di Zhao et al. · 2025 · Journal of the American Chemical Society
  92. Virus neutralisation by intracellular antibodies
    Maria Bottermann, Sarah Caddy · 2021 · Seminars in Cell and Developmental Biology
  93. Oocytes can repair DNA damage during meiosis via a microtubule-dependent recruitment of CIP2A–MDC1–TOPBP1 complex from spindle pole to chromosomes
    Jiyeon Leem, Jae‐Sung Kim, Jeong Su Oh · 2023 · Nucleic Acids Research
  94. Genetically-encoded targeted protein degradation technology to remove endogenous condensation-prone proteins and improve crop performance
    Ming Luo, Sitao Zhu, Hua Dang, Qing Wen, Ruixia Niu, Jiawei Long, Zhao Wang, Yongjia Tong, Yuese Ning, Meng Yuan et al. · 2025 · Nature Communications
  95. Tubulin post-translational modifications in meiosis
    Takashi Akera · 2021 · Seminars in Cell and Developmental Biology
  96. Cyclin B3 implements timely vertebrate oocyte arrest for fertilization
    Nora Bouftas, Lena Schneider, Marc Halder, Rebecca Demmig, Martina Baack, Damien Cladière, Melanie Walter, Hiba Al Abdallah, Camilla Kleinhempel, Ria Messaritaki et al. · 2022 · Developmental Cell
  97. Towards understanding centriole elimination
    Nils Kalbfuß, Pierre Gönczy · 2023 · Open Biology
  98. A framework for TRIM21-mediated protein depletion in early mouse embryos: recapitulation of Tead4 null phenotype over three days
    Steffen Israel, Ellen Casser, Hannes C. A. Drexler, Georg Fuellen, Michele Boiani · 2019 · BMC Genomics
  99. GPC3-mediated lysosome-targeting chimeras (GLTACs) for targeted degradation of membrane proteins
    Yuxin Fang, Yaojin Zhu, Wei Wang, Zhewei Xia, Shipeng He, Guoqiang Dong, Chunquan Sheng · 2025 · Acta Pharmaceutica Sinica B
  100. The nucleolus-like and precursor bodies of mammalian oocytes and embryos and their possible role in post-fertilization centromere remodelling
    J. Fulka, Jana Rychtářová, Pasqualino Loi · 2020 · Biochemical Society Transactions