Optical Pooled Screens in Human Cells
Feldman, David, Singh, Avtar, Schmid-Burgk, Jonathan L., Carlson, Rebecca J., Mezger, Anja, Garrity, Anthony J., Zhang, Feng, Blainey, Paul C.·2019·Cell
Cited by (322)
Items 101–200 of 322
- Pooled Genome-Scale CRISPR Screens in Single CellsDaniel Schraivogel, Lars Michael Steinmetz, Leopold Parts · 2023 · Annual Review of Genetics
- High throughput microscopy and single cell phenotypic image-based analysis in toxicology and drug discoveryFabio Stossi, Pankaj K. Singh, Kazem Safari, Michela Marini, Demetrio Labate A, Michael A. Mancini · 2023 · Biochemical Pharmacology
- Pre-determined diversity in resistant fates emerges from homogenous cells after anti-cancer drug treatmentYogesh Goyal, Ian P. Dardani, Gianna T. Busch, Benjamin L. Emert, Dylan Fingerman, Amanpreet Kaur, Naveen Jain, Ian A. Mellis, Jingxin Li, Karun Kiani et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- Accurate single-molecule spot detection for image-based spatial transcriptomics with weakly supervised deep learningEmily Laubscher, Xuefei Julie Wang, Nitzan Razin, Tom Dougherty, Rosalind J. Xu, Lincoln J. Ombelets, Edward Pao, William Graf, Jeffrey R. Moffitt, Yisong Yue et al. · 2024 · Cell Systems
- Human Organoids as an Emerging Tool for Genome ScreeningsFrancesco Andreatta, Delilah F. G. Hendriks, Benedetta Artegiani · 2025 · Annual Review of Biomedical Engineering
- CloneSifter: enrichment of rare clones from heterogeneous cell populationsDavid Feldman, FuNien Tsai, Anthony J. Garrity, Ryan O’Rourke, Lisa Brenan, Patricia Ho, Elizabeth M. Gonzalez, Silvana Konermann, Cory M. Johannessen, Rameen Beroukhim et al. · 2020 · BMC Biology
- Dynamic FRET-FLIM based screening of signal transduction pathwaysRolf Harkes, Olga Kukk, Sravasti Mukherjee, Jeffrey B. Klarenbeek, Bram van den Broek, Kees Jalink · 2021 · Scientific Reports
- Insights on the NF-κB System Using Live Cell Imaging: Recent Developments and Future PerspectivesCise Kizilirmak, Marco Emilio Bianchi, Samuel Zambrano · 2022 · Frontiers in Immunology
- High-content CRISPR screening in tumor immunologyErin A. Holcomb, Ashley N. Pearson, Kassidy Mikala Jungles, Akshay Tate, Jadyn G. James, Long Jiang, Amanda K. Huber, Michael D. Green · 2022 · Frontiers in Immunology
- CROPseq-multi: a universal solution for multiplexed perturbation in high-content pooled CRISPR screensRussell T. Walton, Yue Qin, Bryce Kirby, J Owen Andrews, Mikko Taipale, Byunguk Kang, Paul C. Blainey · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- From sequence to function: Bridging single-molecule kinetics and molecular diversityAchillefs N. Kapanidis, L. Muras, Koushik Sreenivasa, Jagadish Prasad Hazra, John van Noort, Chirlmin Joo, Sebastian Deindl · 2026 · Science
- Simultaneous CRISPR screening and spatial transcriptomics reveals intracellular, intercellular, and functional transcriptional circuitsBinan, Loϊc, Danquah, Serwah, Valakh, Vera, Simonton, Brooke, Bezney, Jon, Nehme, Ralda, Cleary, Brian, Farhi, Samouil L · 2023
- An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screensRobert Coukos, David Yao, Mateo I. Sánchez, Eric T. Strand, Meagan E. Olive, Namrata D. Udeshi, Jonathan S. Weissman, Steven A. Carr, Michael Cory Bassik, Alice Y. Ting · 2021 · eLife
- CRISPR screening in hematology research: from bulk to single-cell levelSarah Meyers, Sofie Demeyer, Jan Cools · 2023 · Journal of Hematology & Oncology
- Causal modelling of gene effects from regulators to programs to traitsMineto Ota, Jeffrey P. Spence, Tony Zeng, Emma Dann, Nikhil Milind, Alexander Marson, Jonathan K. Pritchard · 2025 · Nature
- From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor culturesYuen‐Yi Tseng, Jesse S. Boehm · 2019 · Current Opinion in Genetics & Development
- Pooled Tagging and Hydrophobic Targeting of Endogenous Proteins for Unbiased Mapping of Unfolded Protein ResponsesStephanie E. Sansbury, Yevgeniy V. Serebrenik, Tomer Lapidot, David Geoffrey Smith, George M. Burslem, Ophir Shalem · 2023 · Molecular Cell
- De novo design of miniprotein agonists and antagonists targeting G protein-coupled receptorsEdin Muratspahić, David Feldman, David E. Kim, Xian-Ming Qu, A. Bratovianu, Paula Rivera-Sánchez, Federica Dimitri, Jason Cao, B. P. Cary, M. Belousoff et al. · 2025 · bioRxiv
- Sequential Optimal Experimental Design of Perturbation Screens Guided by Multi-modal PriorsKexin Huang, Romain Lopez, Jan-Christian Hütter, Takamasa Kudo, Antonio Rios, Aviv Regev · 2024 · Lecture notes in computer science
- NIS-Seq enables cell-type-agnostic optical perturbation screeningCaroline I. Fandrey, Marius Jentzsch, Peter Konopka, Alexander Hoch, Katja Blumenstock, Afraa Aqeel Zackria, Salie Maasewerd, Marta Lovotti, Dorothee J. Lapp, Florian N. Gohr et al. · 2024 · Nature Biotechnology
- Spatial perturb-seq: single-cell functional genomics within intact tissue architectureKimberle Shen, Wan Yi Seow, Choong Tat Keng, Michelle Gek Liang Lim, Daryl Shern Lim, Ke Guo, Amine Meliani, Muhammad Irfan Bin Hajis, Bolun Wang, Shyam Prabhakar et al. · 2026 · Nature Communications
- CRISPR for neuroscientistsGeorgios Kalamakis, Randall J. Platt · 2023 · Neuron
- Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and SilencingJiang‐An Yin, Lukas D. Frick, Manuel C. Scheidmann, Tingting Liu, Chiara Trevisan, Ashutosh Dhingra, Anna Spinelli, Yancheng Wu, Longping Yao, Dalila Laura Vena et al. · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Multiparametric Assays for Accelerating Early Drug DiscoveryAlexander Herholt, Sabrina Galinski, Philipp Emanuel Geyer, Moritz J. Rossner, Michael C. Wehr · 2020 · Trends in Pharmacological Sciences
- Imaging-based screens of pool-synthesized cell librariesMichael J. Lawson, Johan Elf · 2021 · Nature Methods
- Advances in Spatial Omics TechnologiesTianxiao Hui, Jian Zhou, Muchen Yao, Ying Xie, Hu Zeng · 2025 · Small Methods
- Bottom-up design of Ca2+ channels from defined selectivity filter geometryYulai Liu, Connor Weidle, Ljubica Mihaljević, Joseph L. Watson, Zhe Li, Le Tracy Yu, Sagardip Majumder, Andrew J. Borst, Kenneth D. Carr, Ryan D. Kibler et al. · 2025 · Nature
- Mantis: High-throughput 4D imaging and analysis of the molecular and physical architecture of cellsIvanov, Ivan E, Hirata-Miyasaki, Eduardo, Chandler, Talon, Cheloor-Kovilakam, Rasmi, Liu, Ziwen, Pradeep, Soorya, Liu, Chad, Bhave, Madhura, Khadka, Sudip, Arias, Carolina et al. · 2024 · PNAS Nexus
- Engineering next-generation microfluidic technologies for single-cell phenomicsCamille L G Lambert, Guido van Mierlo, Johannes Bues, Orane J. Guillaume-Gentil, Bart Deplancke · 2025 · Nature Genetics
- ATM and IRAK1 orchestrate two distinct mechanisms of NF-κB activation in response to DNA damageElodie Bournique, Ambrocio Sanchez, Sunwoo Oh, Daniel Ghazarian, Alisa L. Mahieu, Lavanya Manjunath, Eirene Marie Q. Ednacot, Pedro Ortega, Selma Masri, Ivan Marazzi et al. · 2025 · Nature Structural & Molecular Biology
- A multiplexed epitope barcoding strategy that enables dynamic cellular phenotypic screensTakamasa Kudo, Keara M. Lane, Markus W. Covert · 2022 · Cell Systems
- Causal modeling of gene effects from regulators to programs to traits: integration of genetic associations and Perturb-seqMineto Ota, Jeffrey P. Spence, Tony Zeng, Emma Dann, Alexander Marson, Jonathan K. Pritchard · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Microglial involvement in autism spectrum disorder: insights from human data and iPSC modelsSusanne Michels, Akash Shivling Mali, Henna Jäntti, Mohammad Rezaie, Tarja Malm · 2025 · Brain Behavior and Immunity
- Cell sorters see things more clearly nowDaniel Schraivogel, Lars Michael Steinmetz · 2023 · Molecular Systems Biology
- STASCAN deciphers fine-resolution cell distribution maps in spatial transcriptomics by deep learningYing Wu, Jiayi Zhou, Bofei Yao, Guanshen Cui, Yongliang Zhao, Chun‐Chun Gao, Ying Yang, Shihua Zhang, Yun‐Gui Yang · 2024 · Genome biology
- Massively parallel in vivo Perturb-seq screeningXinhe Zheng, Patrick C. Thompson, Cassandra White, Xin Jin · 2025 · Nature Protocols
- Expansion in situ genome sequencing links nuclear abnormalities to aberrant chromatin regulationAjay S. Labade, Zachary Chiang, Caroline Comenho, Paul Reginato, Andrew C. Payne, Andrew Earl, Rojesh Shrestha, Fabiana M. Duarte, Ehsan Habibi, Ruochi Zhang et al. · 2025 · Science
- Prevalence of and gene regulatory constraints on transcriptional adaptation in single cellsIan A. Mellis, Madeline E. Melzer, Nicholas Bodkin, Yogesh Goyal · 2024 · Genome biology
- CRISPR Screens to Identify Regulators of Tumor ImmunityMartin W. LaFleur, Arlene H. Sharpe · 2021 · Annual Review of Cancer Biology
- A New Image for Cell SortingAndrew J. Filby, Anne Elizabeth Carpenter · 2022 · New England Journal of Medicine
- SPARCS, a platform for genome-scale CRISPR screening for spatial cellular phenotypesNiklas Arndt Schmacke, Sophia Clara Mädler, Georg Wallmann, Andreas Metousis, Marleen Bérouti, Hartmann Harz, Heinrich Leonhardt, Matthias Mann, Veit Hornung · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Expansion in situ genome sequencing links nuclear abnormalities to hotspots of aberrant euchromatin repressionAjay S. Labade, Zachary Chiang, Caroline Comenho, Paul Reginato, Andrew C. Payne, Andrew Earl, Rojesh Shrestha, Fabiana M. Duarte, Ehsan Habibi, Ruochi Zhang et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Selective induction of programmed cell death using synthetic biology toolsKateryna Shkarina, Petr Brož · 2023 · Seminars in Cell and Developmental Biology
- Analyzing the functional effects of DNA variants with gene editingSarah Cooper, Sofia Obolenski, Andrew J. Waters, Andrew Roger Bassett, Matthew A. Coelho · 2024 · Cell Reports Methods
- On knowing a gene: A distributional hypothesis of gene functionJason J. Kwon, Joshua Pan, Guadalupe Gonzalez, William C. Hahn, Marinka Žitnik · 2024 · Cell Systems
- Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screeningMatteo Gentili, Rebecca J. Carlson, Bingxu Liu, Quentin Hellier, J Owen Andrews, Yue Qin, Paul C. Blainey, Nir Hacohen · 2024 · Cell Systems
- Characterizing protein sequence determinants of nuclear condensates by high-throughput pooled imaging with CondenSeqKalli Kappel, Daniel Strebinger, KeHuan Kuo Edmonds, Chau-Duy-Tam Vo, Christopher M. Vockley, Tridib Biswas, Samouil L. Farhi, Rhiannon K. Macrae, Feng Zhang, Aviv Regev · 2025 · Nature Methods
- Single-cell image-based screens identify host regulators of Ebola virus infection dynamicsRebecca J. Carlson, J. J. Patten, George Stefanakis, Brian Y. Soong, Adityanarayanan Radhakrishnan, Avtar K Singh, Naveen Thakur, Kathleen C. F. Sheehan, Gaya K. Amarasinghe, Nir Hacohen et al. · 2025 · Nature Microbiology
- Cellular Models and High-Throughput Screening for Genetic Causality of Intellectual DisabilityChristopher W. Fell, Vanja Nagy · 2021 · Trends in Molecular Medicine
- All-optical electrophysiology with improved genetically encoded voltage indicators reveals interneuron network dynamics in vivoHe Tian, Hunter C. Davis, J. David Wong-Campos, Linlin Z. Fan, Benjamin Gmeiner, Shahinoor Begum, Christopher A. Werley, Gabriel B. Borja, Hansini Upadhyay, Himali Shah et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
- A platform for multimodal in vivo pooled genetic screens reveals regulators of liver functionReuben A. Saunders, William E. Allen, Xingjie Pan, Jaspreet Sandhu, Jiaqi Lu, Thomas K. Lau, Karina Smolyar, Zuri A. Sullivan, Catherine G. Dulac, Jonathan S. Weissman et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Functional genomics in stem cell models: considerations and applicationsKaivalya Shevade, Sailaja Peddada, Karl Mader, Laralynne Przybyla · 2023 · Frontiers in Cell and Developmental Biology
- Using Genomics to Identify Novel Therapeutic Targets for Aortic DiseaseAvanthi Raghavan, James P. Pirruccello, Patrick T. Ellinor, Mark Evan Lindsay · 2023 · Arteriosclerosis Thrombosis and Vascular Biology
- CRISPR screens come into sightDarren J. Burgess · 2019 · Nature Reviews Genetics
- CRISPRmap: Sequencing-free optical pooled screens mapping multi-omic phenotypes in cells and tissueGu, Jiacheng, Iyer, Abhishek, Wesley, Ben, Taglialatela, Angelo, Leuzzi, Giuseppe, Hangai, Sho, Decker, Aubrianna, Gu, Ruoyu, Klickstein, Naomi, Shuai, Yuanlong et al. · 2023
- Directed mutagenesis in plants through genome editing using guide RNA librarySuman Dutta, Debashis Paul, Anjan Das, Sudhir Kumar, Amitava Roy, Anindita Barua, Viswanathan Chinnusamy · 2024 · The Nucleus
- Tools for Intersectional Optical and Chemical Tagging on Cell SurfacesSarah N. Innes-Gold, Hanzeng Cheng, Luping Liu, Adam E. Cohen · 2025 · ACS Chemical Biology
- Machine Learning Approaches to Single-Cell Data Integration and TranslationCaroline Uhler, G. V. Shivashankar · 2022 · Proceedings of the IEEE
- Understanding neural development and diseases using CRISPR screens in human pluripotent stem cell-derived culturesMai Essam Ahmed, Julien Muffat, Yun Li · 2023 · Frontiers in Cell and Developmental Biology
- Pooled CRISPR screening of high-content cellular phenotypes using ghost cytometryAsako Tsubouchi, Yuri An, Yoko Kawamura, Yuichi Yanagihashi, Hirofumi Nakayama, Yuri Murata, Kazuki Teranishi, Soh Ishiguro, Hiroyuki Aburatani, Nozomu Yachie et al. · 2024 · Cell Reports Methods
- Massively parallel phenotyping of variant impact in cancer with Perturb-seq reveals a shift in the spectrum of cell states induced by somatic mutationsOana Ursu, James T. Neal, Emily K. Shea, Pratiksha I. Thakore, Livnat Jerby‐Arnon, Lan Nguyễn, Danielle Ashley Dionne, Celeste Diaz, Julia Bauman, Mariam Mounir Mosaad et al. · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- High-Throughput Identification, Modeling, and Analysis of Cancer Driver Genes In VivoYuning J. Tang, Emily G. Shuldiner, Saswati Karmakar, Monte M. Winslow · 2023 · Cold Spring Harbor Perspectives in Medicine
- De novo design of miniproteins targeting GPCRsEdin Muratspahić, David Feldman, David E. Kim, Xiangli Qu, Ana-Maria Bratovianu, Paula Rivera-Sánchez, Jan Hendrik Voss, Emil Peter Thrane Hertz, Mads Gravers Jeppesen, Federica Dimitri et al. · 2026 · Nature
- A map of signaling responses in the human airway epitheliumKatherine B. McCauley, Kalki Kukreja, Alfredo E. Tovar Walker, Aron B. Jaffe, Allon Moshe Klein · 2024 · Cell Systems
- Deconstructing cancer with precision genome editingGrace A. Johnson, Samuel I. Gould, Francisco J. Sánchez Rivera · 2024 · Biochemical Society Transactions
- Attention-based deep learning for accurate cell image analysisXiangrui Gao, Fan Zhang, Xueyu Guo, Mengcheng Yao, Xiaoxiao Wang, Dong Chen, Genwei Zhang, Xiaodong Wang, Lipeng Lai · 2025 · Scientific Reports
- Functional Neurogenomics to Dissect Disease Mechanisms Across ModelsXinhe Zheng, Jiwen Li, Xin Jin · 2025 · Annual Review of Genomics and Human Genetics
- Breaking enhancers to gain insights into developmental defectsDaniel A. Armendariz, Anjana Sundarrajan, Gary C. Hon · 2023 · eLife
- The Current Situation and Development Prospect of Whole-Genome ScreeningCaiting Yang, Yu Lei, Tinglin Ren, Mingze Yao · 2024 · International Journal of Molecular Sciences
- Genome-scale requirements for dynein-based trafficking revealed by a high-content arrayed CRISPR screenChun Hao Wong, Steven Wingett, Qian Chen, J. Matthew Taliaferro, Douglas Ross‐Thriepland, Simon L. Bullock · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- CRISPR-based genetic screens in human pluripotent stem cells derived neurons and brain organoidsYu Feng Guo, Xinyu Zhao · 2024 · Cell and Tissue Research
- MuCST: restoring and integrating heterogeneous morphology images and spatial transcriptomics data with contrastive learningYu Wang, Zaiyi Liu, Xiaoke Ma · 2025 · Genome Medicine
- Pooled optical screening in bacteria using chromosomally expressed barcodesRuben R. G. Soares, Daniela A. García‐Soriano, Jimmy Larsson, David Fange, Dvir Schirman, Marco Grillo, Anna Knöppel, Beer Chakra Sen, Fabian Svahn, Spartak Zikrin et al. · 2025 · Communications Biology
- Balancing off-target and on-target considerations for optimized CRISPR-Cas9 knockout library designLaura M. Drepanos, Smriti Srikanth, Eleanor G. Kaplan, Spencer T. Shah, Berta Escude Velasco, Sarra Merzouk, John G. Doench · 2026 · Cell Genomics
- In vivo Pooled Screening: A Scalable Tool to Study the Complexity of Aging and Age-Related DiseaseMartin Borch Jensen, Adam Henry Marblestone · 2021 · Frontiers in Aging
- Towards a CRISPeR understanding of homologous recombination with high-throughput functional genomicsSamuel B. Hayward, Alberto Ciccia · 2021 · Current Opinion in Genetics & Development
- High-throughput tagging of endogenous loci for rapid characterization of protein functionJoonwon Kim, Alexander F. Kratz, Shiye Chen, Jenny Sheng, Hark Kyun Kim, Liudeng Zhang, Brijesh Kumar Singh, Alejandro Chavez · 2024 · Science Advances
- Barcodes, co-cultures, and deep learning take genetically encoded biosensor multiplexing to the nth degreeTakuya Terai, Robert E. Campbell · 2022 · Molecular Cell
- Multiplexed functional genomic assays to decipher the noncoding genomeYonatan A. Cooper, Qiuyu Guo, Daniel H. Geschwind · 2022 · Human Molecular Genetics
- Pooled image-base screening of mitochondria with microraft isolation distinguishes pathogenic mitofusin 2 mutationsAlex L. Yenkin, John C. Bramley, Colin L. Kremitzki, Jason E. Waligorski, Mariel J. Liebeskind, Xinyuan E. Xu, Vinay D. Chandrasekaran, Maria A. Vakaki, Graham W. Bachman, Robi David Mitra et al. · 2022 · Communications Biology
- In Vivo Cancer-Based Functional GenomicsChennan Li, Andrea L. Kasinski · 2020 · Trends in cancer
- The necessity and power of random, under-sampled experiments in biologyBrian Cleary, Aviv Regev · 2020 · arXiv (Cornell University)
- High-throughput CRISPRi and CRISPRa technologies in 3D genome regulation for neuropsychiatric diseasesIan Richard Jones, Xingjie Ren, Yin Shen · 2022 · Human Molecular Genetics
- Discovery platforms for RNA therapeuticsGiulio Ciucci, Luca Braga, Serena Zacchigna · 2024 · British Journal of Pharmacology
- A Novel Screening Approach for the Dissection of Cellular Regulatory Networks of NF-κB Using Arrayed CRISPR gRNA LibrariesPatrick Joseph O'Shea, Jan Wildenhain, Mathew Leveridge, Chetana M. Revankar, Jianping Yang, Jenna Bradley, Mike A. Firth, James E. Pilling, David R. Piper, Jonathan D. Chesnut et al. · 2020 · SLAS DISCOVERY
- High-throughput single-cell functional elucidation of neurodevelopmental disease-associated genes reveals convergent mechanisms altering neuronal differentiationMatthew A. Lalli, Denis R. Avey, Joseph D. Dougherty, Jeffrey Milbrandt, Robi David Mitra · 2019 · bioRxiv (Cold Spring Harbor Laboratory)
- Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screeningRamon Lorenzo D. Labitigan, Adrian L. Sanborn, Cynthia V. Hao, Caleb K. Chan, Nathan M. Belliveau, Eva M. Brown, Mansi Mehrotra, Julie A. Theriot · 2024 · eLife
- Technologies to measure and modulate protein subcellular localizationWilliam D. Leineweber, Reika Tei, Anna Mäkiniemi, Alice Y. Ting, Emma K. Lundberg · 2026 · Nature Reviews Molecular Cell Biology
- Single-cell and spatial transcriptomics in endocrine research.Ryusaku Matsumoto, Takuya Yamamoto · 2024 · Endocrine journal
- Towards elucidating disease-relevant states of neurons and glia by CRISPR-based functional genomicsKun Leng, Martin Kampmann · 2022 · Genome Medicine
- Gene-embedding-based prediction and functional evaluation of perturbation expression responses with PRESAGERussell Littman, Jacob Levine, Sepideh Maleki, Yong‐Ju Lee, V. Yu. Ermakov, Lin Qiu, Alexander P. Wu, Kexin Huang, Romain Lopez, Gabriele Scalia et al. · 2025 · bioRxiv (Cold Spring Harbor Laboratory)
- Single-cell and spatial profiling in cancer biology and clinical oncologyChris J. Frangieh, Joy Linyue Fan, Johannes C. Melms, Parin Shah, Elham Azizi, Benjamin Izar · 2026 · Nature Cancer
- High‐throughput, microscopy‐based screening and quantification of genetic elementsRongrong Zhang, Ya-Jia Huang, Mei Li, Lei Wang, Bing Li, Ai-Guo Xia, Ye Li, Shuai Yang, Fan Jin · 2023 · bioRxiv
- AI: A transformative opportunity in cell biologyAmbrose Carr, Jonah Cool, Theofanis Karaletsos, Donghui Li, Alan R. Lowe, Stephani Otte, Sandra L. Schmid · 2024 · Molecular Biology of the Cell
- Tools for Decoding Ubiquitin Signaling in DNA RepairBenjamin Foster, Martin Attwood, Ian Gibbs‐Seymour · 2021 · Frontiers in Cell and Developmental Biology
- Genome-scale requirements for dynein-based transport revealed by a high-content arrayed CRISPR screenChun Hao Wong, Steven Wingett, Qian Chen, Morag Rose Hunter, J. Matthew Taliaferro, Douglas Ross‐Thriepland, Simon L. Bullock · 2024 · The Journal of Cell Biology
- Mapping variation in the morphological landscape of human cells with optical pooled CRISPRi screeningRamon Lorenzo D. Labitigan, Adrian L. Sanborn, Cynthia V. Hao, Caleb K. Chan, Nathan M. Belliveau, Eva M. Brown, Mansi Mehrotra, Julie A. Theriot · 2022 · bioRxiv (Cold Spring Harbor Laboratory)
- Multi-ContrastiveVAE disentangles perturbation effects in single cell images from optical pooled screensZitong Jerry Wang, Romain Lopez, Jan-Christian Hütter, Takamasa Kudo, Heming Yao, Philipp Hanslovsky, Burkhard Höckendorf, Rahul Moran, David Richmond, Aviv Regev · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- High-throughput optimized prime editing mediated endogenous protein tagging for pooled imaging of protein localizationHenry Sanchez, Tomer Lapidot, Ophir Shalem · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Weakly Supervised Set-Consistency Learning Improves Morphological Profiling of Single-Cell ImagesHeming Yao, Phil Hanslovsky, Jan-Christian Huetter, Burkhard Höckendorf, David Richmond · 2024 · IEEE/CVF Conference on Computer Vision and Pattern Recognition Workshops (CVPRW)