Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2

Wang, Qihui, Zhang, Yanfang, Wu, Lili, Niu, Sheng, Song, Chunli, Zhang, Zengyuan, Lu, Guangwen, Qiao, Chengpeng +6 more·2020·Cell

DOI 10.1016/j.cell.2020.03.045

Cited by (1,009)

Items 601–700 of 1,009

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Q. Yan, P. He, Xiaohan Huang, K. Luo, Yu-Di Zhang, Haisu Yi, Qian Wang, Feng Li, Rui-Tian Hou, Xiaodi Fan et al. · 2021 · Emerging Microbes and Infections
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Wan-Ling Wu, Chen-Yi Chiang, Szu-Chia Lai, Chia-Yi Yu, Yu‐Ling Huang, Hung‐Chun Liao, Ching‐Len Liao, Hsin–Wei Chen, Shih‐Jen Liu · 2022 · JCI Insight
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Tümay Capraz, Nikolaus F. Kienzl, Elisabeth Laurent, Jan Walther Perthold, Esther Föderl-Höbenreich, Clemens Grünwald‐Gruber, Daniel Maresch, Vanessa Monteil, Janine Niederhöfer, Gerald Wirnsberger et al. · 2021 · eLife
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Derek Miller, Valeria Garcia‐Flores, Roberto J. Romero, José Galaz, Roger Piqué-Regi, Nardhy Gomez‐Lopez · 2022 · The Journal of Immunology
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Cristina García‐Iriepa, Cécilia Hognon, Antonio Francés‐Monerris, Isabel Iriepa, Tom Miclot, Giampaolo Barone, Antonio Monari, Marco Marazzi · 2020 · The Journal of Physical Chemistry Letters
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