Cited by 406Microbial Metabolic Engineering and BioproductionBiofuel production and bioconversionBioeconomy and Sustainability Development

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Biofuels for a sustainable future

Open access

Liu, Yuzhong, Cruz-Morales, Pablo, Zargar, Amin, Belcher, Michael S., Pang, Bo, Englund, Elias, Dan, Qingyun, Yin, Kevin, Keasling, Jay D.·2021·Cell

DOI 10.1016/j.cell.2021.01.052

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Abstract

Rapid increases of energy consumption and human dependency on fossil fuels have led to the accumulation of greenhouse gases and consequently, climate change. As such, major efforts have been taken to develop, test, and adopt clean renewable fuel alternatives. Production of bioethanol and biodiesel from crops is well developed, while other feedstock resources and processes have also shown high potential to provide efficient and cost-effective alternatives, such as landfill and plastic waste conversion, algal photosynthesis, as well as electrochemical carbon fixation. In addition, the downstream microbial fermentation can be further engineered to not only increase the product yield but also expand the chemical space of biofuels through the rational design and fine-tuning of biosynthetic pathways toward the realization of "designer fuels" and diverse future applications.

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Additional file 1 of Combination of genetic engineering and random mutagenesis for improving production of raw-starch-degrading enzymes in Penicillium oxalicum
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Additional file 3 of Combination of genetic engineering and random mutagenesis for improving production of raw-starch-degrading enzymes in Penicillium oxalicum
Zhao, S., Tan, M.-Z., Wang, R.-X., Ye, F.-T., Chen, Y.-P., Luo, X.-M., & Feng, J.-X. (2023) · Figshare · doi:10.6084/m9.figshare.22608067
Additional file 1 of Engineering isoprenoids production in metabolically versatile microbial host Pseudomonas putida
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Additional file 6 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
Barros, K. O., Mader, M., Krause, D. J., Pangilinan, J. L., Andreopoulos, B., Lipzen, A., Mondo, S. J., Grigoriev, I. V., Rosa, C. A., Sato, T. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26677883
Additional file 5 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
Barros, K. O., Mader, M., Krause, D. J., Pangilinan, J. L., Andreopoulos, B., Lipzen, A., Mondo, S. J., Grigoriev, I. V., Rosa, C. A., Sato, T. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26677880
Additional file 3 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
Barros, K. O., Mader, M., Krause, D. J., Pangilinan, J. L., Andreopoulos, B., Lipzen, A., Mondo, S. J., Grigoriev, I. V., Rosa, C. A., Sato, T. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.26677874
Additional file 2 of Combination of genetic engineering and random mutagenesis for improving production of raw-starch-degrading enzymes in Penicillium oxalicum
Zhao, S., Tan, M.-Z., Wang, R.-X., Ye, F.-T., Chen, Y.-P., Luo, X.-M., & Feng, J.-X. (2023) · Figshare · doi:10.6084/m9.figshare.22608064
Additional file 5 of Combination of genetic engineering and random mutagenesis for improving production of raw-starch-degrading enzymes in Penicillium oxalicum
Zhao, S., Tan, M.-Z., Wang, R.-X., Ye, F.-T., Chen, Y.-P., Luo, X.-M., & Feng, J.-X. (2023) · Figshare · doi:10.6084/m9.figshare.22608073
Additional file 4 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
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Additional file 1 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
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Additional file 2 of Oxygenation influences xylose fermentation and gene expression in the yeast genera Spathaspora and Scheffersomyces
Barros, K. O., Mader, M., Krause, D. J., Pangilinan, J. L., Andreopoulos, B., Lipzen, A., Mondo, S. J., Grigoriev, I. V., Rosa, C. A., Sato, T. K., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25157829
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Authors: Liu, Y., Cruz-Morales, P., Zargar, A., Belcher, M. S., Pang, B., Englund, E., Dan, Q., Yin, K., & Keasling, J. D.
Affiliations: QB3 (US)
Lawrence Berkeley National Laboratory (US)
Corresponding author: Keasling, Jay D.
ORCID: Liu, Yuzhong
Cruz-Morales, Pablo
Belcher, Michael S.
Pang, Bo
Englund, Elias
Dan, Qingyun
Yin, Kevin
Keasling, Jay D.
Venue: Cell
Publisher: Elsevier BV
Published: 2021-03
Volume: 184
Issue: 6
Pages: 1636-1647
ISSN: 0092-8674 (ISSN-L)
DOI: 10.1016/j.cell.2021.01.052
OpenAlex: W3134876231
Cited by: 399
References: 90
Citations by year: 2026: 47 · 2025: 86 · 2024: 105 · 2023: 78 · 2022: 62 · 2021: 21
FWCI: 7.03
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/legal/tdmrep-license (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 383 d)
doi.org/10.15223/policy-017 (stm-asf)
doi.org/10.15223/policy-037 (stm-asf)
doi.org/10.15223/policy-012 (stm-asf)
doi.org/10.15223/policy-029 (stm-asf)
doi.org/10.15223/policy-004 (stm-asf)
Locations: Cell (publishedVersion)
PubMed (publishedVersion)
eScholarship (California Digital Library) (submittedVersion)
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information) (submittedVersion)
Technical University of Denmark, DTU Orbit (Technical University of Denmark, DTU) (submittedVersion, cc-by-nc-nd)
Funders: U.S. Department of Energy (05CH11231, DE AC02 05CH11231)
Office of Science (DEAC02–05CH11231, 05CH11231)
Office of Energy Efficiency and Renewable Energy (DE- AC02-05CH11231)
Biological and Environmental Research (05CH11231, DE-AC02 − 05CH11231)
Office of Energy Efficiency
Lawrence Berkeley National Laboratory (DE-AC02-05CH11231, 05CH11231)
Topics: Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Microbial Metabolic Engineering and Bioproduction
Physical Sciences › Engineering › Biomedical Engineering › Biofuel production and bioconversion
Life Sciences › Agricultural and Biological Sciences › General Agricultural and Biological Sciences › Bioeconomy and Sustainability Development
Keywords: biofuels, renewable energy, bioethanol, biodiesel, greenhouse gas emissions, climate change, waste plastic conversion, algal photosynthesis, microbial fermentation, biosynthetic pathway engineering, sustainable energy
MeSH terms: Sustainable Development, Humans, Lignin, Waste Products, Biosynthetic Pathways, Biofuels, Carbon Cycle

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