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Cited by 239

The DOI matches its Crossref record; 99 of the 99 references it cites were found in a registry or an index.

Human brain organogenesis: Toward a cellular understanding of development and disease

Open access
Kelley, Kevin W., Pașca, Sergiu P.·2022·Cell

Abstract

SUMMARY The construction of the human nervous system is a distinctly complex although highly regulated process. Human tissue inaccessibility has impeded a molecular understanding of the developmental specializations from which our unique cognitive capacities arise. A confluence of recent technological advances in genomics and stem cell-based tissue modeling is laying the foundation for a new understanding of human neural development and dysfunction in neuropsychiatric disease. Here, we review recent progress on uncovering the cellular and molecular principles of human brain organogenesis in vivo as well as using organoids and assembloids in vitro to model features of human evolution and disease.

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Crossref · 10.1016/j.cell.2021.10.003

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Metadata

Authors
Kelley, K. W., & Pașca, S. P.
Venue
Cell
Publisher
Elsevier BV
Published
2022-01
Volume
185
Issue
1
Pages
42-61
ISSN
0092-8674 (ISSN-L)
OpenAlex
W3211792717
Cited by
239
References
99
FWCI
11.65
Type
journal article
Language
en
Open access
bronze

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CoChat. (2026). Citation check: Human brain organogenesis: Toward a cellular understanding of development and disease. https://app.cochat.ai/papers/10.1016/j.cell.2021.10.003
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Kelley, K. W., & Pașca, S. P. (2022). Human brain organogenesis: Toward a cellular understanding of development and disease. Cell. https://doi.org/10.1016/j.cell.2021.10.003

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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.