Establishing a blockchain-enabled Indigenous data sovereignty framework for genomic data
Open accessAbstract
Technological advances have enabled the rapid generation of health and genomic data, though rarely do these technologies account for the values and priorities of marginalized communities. In this commentary, we conceptualize a blockchain genomics data framework built out of the concept of Indigenous Data Sovereignty.
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Smart contracts can automatically enforce consent parameters, such as temporal limitations, usage restrictions, or benefit-sharing triggers.
“Additionally, smart contracts can automatically enforce consent parameters, such as temporal limitations, usage restrictions, or benefit-sharing triggers (Mackey et al. 2022).”
From Preventing AI extractivism: the case for braiding indigenous data justice with ABS for stronger AI data governance (2026) · cites this paper as Mackey et al. 2022
The Background says smart contracts can execute predetermined conditions for data access and sharing and can automate an agreement after community approval. It does not specify temporal limitations, usage restrictions, or benefit-sharing triggers as conditions those contracts enforce. (LLM, conf=0.88)
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- Authors
- Mackey, T. K., Calac, A. J., Chenna Keshava, B. S., Yracheta, J., Tsosie, K. S., & Fox, K.
- Affiliations
- San Diego Supercomputer Center (US)
- University of California San Diego (US)
- Corresponding author
- Fox, Keolu
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2022-07
- Volume
- 185
- Issue
- 15
- Pages
- 2626-2631
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W4286266880
- Cited by
- 36
- References
- 14
- Citations by year
- 2026: 8 · 2025: 10 · 2024: 12 · 2023: 6
- FWCI
- 6.93
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Licence
- www.elsevier.com/tdm/userlicense/1.0/ (tdm)
- www.elsevier.com/legal/tdmrep-license (tdm)
- www.elsevier.com/open-access/userlicense/1.0/ (vor, 385 d)
- doi.org/10.15223/policy-017 (stm-asf)
- doi.org/10.15223/policy-037 (stm-asf)
- doi.org/10.15223/policy-012 (stm-asf)
- doi.org/10.15223/policy-029 (stm-asf)
- doi.org/10.15223/policy-004 (stm-asf)
- Locations
- Cell (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Physical Sciences › Computer Science › Information Systems › Blockchain Technology Applications and Security
- Social Sciences › Health › Indigenous Health, Education, and Rights
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Race, Genetics, and Society
- Keywords
- blockchain, Indigenous data sovereignty, genomic data, health data, data governance, indigenous peoples, marginalized communities, data ownership
- MeSH terms
- Blockchain, Technology, Computer Security, Genomics
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