The DOI matches its Crossref record; 234 of the 234 references it cites were found in a registry or an index.
Mitochondria at the crossroads of health and disease
Open accessAbstract
Mitochondria reside at the crossroads of catabolic and anabolic metabolism-the essence of life. How their structure and function are dynamically tuned in response to tissue-specific needs for energy, growth repair, and renewal is being increasingly understood. Mitochondria respond to intrinsic and extrinsic stresses and can alter cell and organismal function by inducing metabolic signaling within cells and to distal cells and tissues. Here, we review how the centrality of mitochondrial functions manifests in health and a broad spectrum of diseases and aging.
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Citations
Cites
Sequence and organization of the human mitochondrial genome
Anderson, S., Bankier, A. T., Barrell, B. G., de Bruijn, M. H. L., Coulson, A. R., Drouin, J., Eperon, I. C., Nierlich, D. P., Roe, B. A., Sanger, F., et al. (1981) · Nature · doi:10.1038/290457a0 · Cited by 9,636
How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal · doi:10.1042/bj20081386 · Cited by 8,207
Hallmarks of aging: An expanding universe
López-Otín, C., Blasco, M. A., Partridge, L., Serrano, M., & Kroemer, G. (2023) · Cell · doi:10.1016/j.cell.2022.11.001 · Cited by 6,549
AMPK: guardian of metabolism and mitochondrial homeostasis
Herzig, S., & Shaw, R. J. (2018) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm.2017.95 · Cited by 4,061
Parkin is recruited selectively to impaired mitochondria and promotes their autophagy
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An epigenetic biomarker of aging for lifespan and healthspan
Levine, M. E., Lu, A. T., Quach, A., Chen, B. H., Assimes, T. L., Bandinelli, S., Hou, L., Baccarelli, A. A., Stewart, J. D., Li, Y., et al. (2018) · Aging · doi:10.18632/aging.101414 · Cited by 3,675
Mitochondrial TCA cycle metabolites control physiology and disease
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One-Carbon Metabolism in Health and Disease
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Mitochondrial DNA mutations, oxidative stress, and apoptosis in mammalian aging
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ER Tubules Mark Sites of Mitochondrial Division
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Self-citation
Cited by
Mitophagy in the pathogenesis and management of disease
Wang, Q., Sun, Y., Li, T. Y., & Auwerx, J. (2026) · Cell Research · doi:10.1038/s41422-025-01203-7 · Cited by 103
An integrative modelling approach to the mitochondrial cristae
(2025) · doi:10.1038/s42003-025-08381-5 · Cited by 21
Membranes arrest the coarsening of mitochondrial condensates in human cells
(2026) · doi:10.1038/s42003-026-10085-3 · Cited by 2
Metadata
- Authors
- Suomalainen, A., & Nunnari, J.
- Venue
- Cell
- Publisher
- Elsevier BV
- Published
- 2024-05
- Volume
- 187
- Issue
- 11
- Pages
- 2601-2627
- ISSN
- 0092-8674 (ISSN-L)
- OpenAlex
- W4398231688
- Cited by
- 478
- References
- 234
- FWCI
- 55.54
- Type
- journal article
- Language
- en
- Open access
- hybrid
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Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
