The DOI matches its Crossref record; 132 of the 133 references it cites were found in a registry or an index.
Signal transduction of bone morphogenetic protein receptors
Abstract
Bone morphogenetic proteins (BMPs) play a crucial role during all stages of embryonic development. Although only two major signaling pathways have been characterized (the p38 and Smad pathways), the BMP signaling is complex and includes several negative feedback mechanisms. This article reviews the current state of BMP receptor signaling and provides a summary of the crosstalk of the BMP receptor pathway with other major signaling pathways.
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“The GAA triplet-repeat expansion in the frataxin gene was shown to interfere with frataxin gene transcription (223) because of a self-associated triplex formation at long GAA:TTC repeats (sticky DNA) (22, 193, 267, 268).”
From Intracellular iron transport and storage: from molecular mechanisms to health implications (2008) · cites this paper as [223]
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Cites
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Özmen, Ö. (2022) · Acta Veterinaria Hungarica · doi:10.1556/004.2022.00037
SUN, Z., Cai, S., LIU, X., Jiang, W. G., & Ye, L. (2024) · Cancer Diagnosis & Prognosis · doi:10.21873/cdp.10365
Halloran, D. R., Pandit, V., Chukwuocha, K., & Nohe, A. (2024) · Journal of Developmental Biology · doi:10.3390/jdb12040030 · Cited by 2
Self-citation(2025) · Thieme Medical Publishers eBooks · doi:10.1055/b-0045-212051
Reticulophagy receptor FAM134C restrains BMP receptor signaling
Gu, S., Zhang, H., Cao, J., He, Z., Wu, J., Liu, X., Zheng, M., Liu, T., Zhao, B., Xu, P., et al. (2025) · The EMBO Journal · doi:10.1038/s44318-025-00581-3
Hrubi, E., Tóth, F., Nagy, G. N., Tőzsér, J., & Hegedűs, C. (2025) · Biomolecules · doi:10.3390/biom15121704
Proteomics Analysis of TGFβ Superfamily Members
Souchelnytskyi, S. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-292-2_20
He, H., Yang, Y.-H., Yang, X., & Huang, Y. (2024) · Figshare · doi:10.6084/m9.figshare.25329697
Skeletal muscle growth and maintenance depend on BMP signaling
Schirwis, E. (2014) · theses.fr (ABES) · doi:10.70675/7234357bz1f9dz4a42za02cz799ec1dedf12
BMP signaling controls postnatal muscle development
Stantzou, A. (2015) · theses.fr (ABES) · doi:10.70675/5f5055dezcb3dz4bdbz84e8zb743b6f0172d
SMAD6-mediated modulation of BMP/TGF-β signaling disrupts midbrain growth in chick embryos
Moschou, D., Richter, A., & Wizenmann, A. (2026) · Discover Neuroscience · doi:10.1186/s13064-026-00328-8
BindingDB Entry 50015692: Phenotypic Discovery of Triazolo[1,5-
BindingDB (2023) · UC San Diego · doi:10.7270/q2fx7fft
Role of Bone Morphogenetic Proteins in Valvulogenesis
Gould, R. A., & Butcher, J. T. (2013) · Springer eBooks · doi:10.1007/978-1-4471-4429-8_36
Metadata
- Authors
- Nohe, A.
- Affiliations
- Western University (CA)
- Corresponding author
- Nohe, A
- ORCID
- Nohe, A
- Venue
- Cellular Signalling
- Publisher
- Elsevier BV
- Published
- 2004-03
- Volume
- 16
- Issue
- 3
- Pages
- 291-299
- ISSN
- 0898-6568 (ISSN-L)
- OpenAlex
- W2093271566
- Cited by
- 514
- References
- 133
- Citations by year
- 2026: 3 · 2025: 5 · 2024: 11 · 2023: 7 · 2022: 17 · 2021: 10 · 2020: 12 · 2019: 9 · 2018: 17 · 2017: 16 · 2016: 30 · 2015: 31 · 2014: 22 · 2013: 26 · 2012: 31
- FWCI
- 7.24
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Cellular Signalling (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › TGF-β signaling in diseases
- Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Developmental Biology and Gene Regulation
- Health Sciences › Medicine › Rheumatology › Heterotopic Ossification and Related Conditions
- Keywords
- bone morphogenetic proteins, BMP receptors, signal transduction, Smad signaling, p38 MAPK pathway, negative feedback regulation, signaling crosstalk, embryonic development
- MeSH terms
- Animals, Carrier Proteins, DNA-Binding Proteins, Models, Biological, Signal Transduction, Trans-Activators, Receptors, Growth Factor, Mitogen-Activated Protein Kinases, MAP Kinase Signaling System, Feedback, Physiological, p38 Mitogen-Activated Protein Kinases, Adaptor Proteins, Signal Transducing, Smad Proteins, Bone Morphogenetic Protein Receptors
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