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Co-activation of AMPK and mTORC1 Induces Cytotoxicity in Acute Myeloid Leukemia

Sujobert, Pierre, Poulain, Laury, Paubelle, Etienne, Zylbersztejn, Florence, Grenier, Adrien, Lambert, Mireille, Townsend, Elizabeth C., Brusq, Jean-Marie, Nicodeme, Edwige, Decrooqc, Justine, Nepstad, Ina, Green, Alexa S., Mondesir, Johanna, Hospital, Marie-Anne, Jacque, Nathalie, Christodoulou, Alexandra, Desouza, Tiffany A., Hermine, Olivier, Foretz, Marc, Viollet, Benoit, Lacombe, Catherine, Mayeux, Patrick, Weinstock, David M., Moura, Ivan C., Bouscary, Didier, Tamburini, Jerome·2015·Cell Reports
DOI 10.1016/j.celrep.2015.04.063
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Crossref · 10.1016/j.celrep.2015.04.063

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9 of 9 references verified0 citation errors · 0 not checkable

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Image 4
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Figure 2 GSK621 Induces Anti-leukemic Activity in AML
Figure 2 GSK621 Induces Anti-leukemic Activity in AMLCC-BY-NC-ND · From the PDF
Image 8
CC-BY-NC-ND · From the PDF
Figure 3 Autophagy Is a Trigger of GSK621-Induced AML Cell Death
Figure 3 Autophagy Is a Trigger of GSK621-Induced AML Cell DeathCC-BY-NC-ND · From the PDF
Image 10
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Figure 4 AMPK and mTORC1 Co-activation Is Synthetically Lethal in AML
Figure 4 AMPK and mTORC1 Co-activation Is Synthetically Lethal in AMLCC-BY-NC-ND · From the PDF
Unfold Protein Response
Unfold Protein ResponseCC-BY-NC-ND · From the PDF
Figure 5 Synthetic Lethality between AMPK and mTORC1 Involves eIF2 a /ATF4
Figure 5 Synthetic Lethality between AMPK and mTORC1 Involves eIF2 a /ATF4CC-BY-NC-ND · From the PDF
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Citations

Cites

Research works printed but not linked: 42

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Metadata

Authors
Sujobert, P., Poulain, L., Paubelle, E., Zylbersztejn, F., Grenier, A., Lambert, M., Townsend, E. C., Brusq, J.-M., Nicodeme, E., Decrooqc, J., Nepstad, I., Green, A. S., Mondesir, J., Hospital, M.-A., Jacque, N., Christodoulou, A., Desouza, T. A., Hermine, O., Foretz, M., Viollet, B., Lacombe, C., Mayeux, P., Weinstock, D. M., Moura, I. C., Bouscary, D., & Tamburini, J.
Venue
Cell Reports
Publisher
Elsevier BV
Published
2015-06
Volume
11
Issue
9
Pages
1446-1457
ISSN
2211-1247
DOI
10.1016/j.celrep.2015.04.063
Cited by
114
References
9
Language
en
Licence

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