Organoid Models of Human Liver Cancers Derived from Tumor Needle Biopsies

Nuciforo, Sandro, Fofana, Isabel, Matter, Matthias S., Blumer, Tanja, Calabrese, Diego, Boldanova, Tujana, Piscuoglio, Salvatore, Wieland, Stefan, Ringnalda, Femke, Schwank, Gerald, Terracciano, Luigi M., Ng, Charlotte K.Y., Heim, Markus H.·2018·Cell Reports
DOI 10.1016/j.celrep.2018.07.001

Cited by (481)

Items 301–400 of 481

  1. Strategic use of organoids and organs-on-chip as biomimetic tools
    Anderson Kenedy Santos, Sérgio Scalzo, Raysa T. V. Souza, Pedro H. G. Santana, Bruno Lemes Marques, Lucas Felipe de Oliveira, Daniel Mendes Filho, Alexandre Hiroaki Kihara, Helton C. Santiago, Ricardo Cambraia Parreira et al. · 2022 · Seminars in Cell and Developmental Biology
  2. Organoids for Modeling (Colorectal) Cancer in a Dish
    Florian Rathje, Stefan Klingler, Fritz Aberger · 2022 · Cancers
  3. Genomic analysis of focal nodular hyperplasia with associated hepatocellular carcinoma unveils its malignant potential: a case report
    Caner Ercan, Mairene Coto‐Llerena, John Gallon, Lana Fourie, Mattia Marinucci, Gabriel Fridolin Hess, Jürg Vosbeck, Stephanie Taha‐Mehlitz, Tuyana Boldanova, Marie‐Anne Meier et al. · 2022 · Communications Medicine
  4. Loss of heterozygosity of CYP2D6 enhances the sensitivity of hepatocellular carcinomas to talazoparib
    Xiaonan Zhang, Natallia Rameika, Lei Zhong, Verónica Rendo, Margus Veanes, Snehangshu Kundu, Sandro Nuciforo, Jordan Dupuis, Muhammad Azhar, Ioanna Tsiara et al. · 2024 · EBioMedicine
  5. Organoid models of breast cancer in precision medicine and translational research
    Vahid Niazi, Benyamin Parseh · 2024 · Molecular Biology Reports
  6. Current applications, future Perspectives and challenges of Organoid technology in oral cancer research
    Yunyi Wang, Xiang Ying Sun, Bingxu Lu, Danya Zhang, Yaping Yin, Shuguang Liu, Lei Chen, Zhaoqiang Zhang · 2025 · European Journal of Pharmacology
  7. Hepatobiliary organoid research: the progress and applications
    Rui-Qi Zou, Yu-Shi Dai, Fei Liu, Siqi Yang, Hai‐Jie Hu, Fu‐Yu Li · 2025 · Frontiers in Pharmacology
  8. Liver and bile duct organoids and tumoroids
    Xuanming Luo, Yuda Gong, Zijun Gong, Kun Fan, Tao Suo, Han Liu, Xiaoling Ni, Xiaoling Ni, Miyesaier Abudureyimu, Houbao Liu · 2024 · Biomedicine & Pharmacotherapy
  9. 3D Organoid modelling of hepatoblast-like and mesenchymal-like hepatocellular carcinoma cell lines
    Özden Öz, Evin İşcan, Tuğçe Batur, Mehmet Öztürk · 2021 · Hepatoma Research
  10. Role of Biobanks for Cancer Research and Precision Medicine in Hepatocellular Carcinoma
    Peyda Korhan, Sanem Tercan Avcı, Yeliz Yılmaz, Yasemin Öztemur Islakoğlu, Neşe Atabey · 2021 · Journal of Gastrointestinal Cancer
  11. Updates on Organoid Model for the Study of Liver Cancer
    Korri Elvanita El-Khobar, Caecilia Hapsari Ceriapuri Sukowati · 2023 · Technology in Cancer Research & Treatment
  12. Correlation of the treatment sensitivity of patient-derived organoids with treatment outcomes in patients with head and neck cancer (SOTO): protocol for a prospective observational study
    Ifigenia Vasiliadou, Christiana Cattaneo, Phoebe Yuen Ka Chan, Rhonda Henley‐Smith, Harry Gregson-Williams, Lisette Collins, Gabriella Wojewodka, Teresa Guerrero Urbano, Jean‐Pierre Jeannon, Steve E. J. Connor et al. · 2024 · BMJ Open
  13. Pathologic complete response to conversion therapy in hepatocellular carcinoma using patient-derived organoids: A case report
    Yonggang He, Zheng Wang, Jing Li, Xi Wang, Chong-Yu Zhao, Xiaobing Huang, Lu Zheng · 2024 · World Journal of Gastrointestinal Oncology
  14. Differences in chemotherapeutic drug sensitivity before and after patient-derived tumor organoid construction
    Fang Shao, Xin Hua Huang, Zhihong Ma, Liqin Li, Chunjian Qi · 2025 · Toxicology and Applied Pharmacology
  15. Oxytocin Receptor Regulates the Hippo/YAP Axis to Drive Hepatocarcinogenesis
    Huijie Yang, Jin Cui, Peng Su, Xiujie Cui, Haojie Guo, Penghe Yang, Shuqing Zhang, Chenmiao Zhang, Mingxi Fu, Zhongbo Li et al. · 2025 · Cancer Research
  16. Engineering Complexity: Advances in 3D Breast Cancer Models for Precision Oncology
    Wonwoo Jeong, Sang Jin Lee · 2025 · Advanced Healthcare Materials
  17. Head and neck cancer organoids: a panoramic perspective from basic construction to clinical translation
    Ruoyu Meng, Lianpin Yu, Xiaomei Li, Na Ning, Haibin Hao, Xiaonan Zhang, Wei Song, Wei Song, Xinyu Li · 2025 · Stem Cell Research & Therapy
  18. Mastering Organoid Growth: A Complete Guide to Overcoming Methodological Challenges
    Chunbao Jiao, Omer Faruk Karakaya, Neda Dadgar, Chase J. Wehrle, Zahra Massoud, Hanna Hong, Robert L. Fairchild, Nic D. Leipzig, Federico Aucejo, Wen Wee Ma et al. · 2026 · MedComm
  19. Liver organoids as a primary human model to study HBV-mediated Hepatocellular carcinoma. A review
    Simran Sharma, Preety Rawal, Savneet Kaur, Rekha Puria · 2023 · Experimental Cell Research
  20. Organoids for Cancer Research: Advances and Challenges
    Miaomaio Xin, Qian Li, Dongyang Wang, Zheng Wang · 2024 · Advanced Biology
  21. Organoid as a promising tool for primary liver cancer research: a comprehensive review
    Xuekai Hu, Jiayun Wei, Pinyan Liu, Qiuxia Zheng, Yue Zhang, Qichen Zhang, Jia Yao, Jingman Ni · 2024 · Cell & Bioscience
  22. Targeting Dysregulated Ion Channels in Liver Tumors with Venom Peptides
    Achimba, Favour, Faezov, Bulat, Cohen, Brandon, Dunbrack, Roland, Holford, Mandë · 2024 · Molecular Cancer Therapeutics
  23. Studying the Role of Chromosomal Instability (CIN) in GI Cancers Using Patient-derived Organoids
    Shalaka Patil, Sanika Jahagirdar, Maithilee Khot, Kundan Sengupta · 2021 · Journal of Molecular Biology
  24. Development of Liver Cancer Organoids: Reproducing Tumor Microenvironment and Advancing Research for Liver Cancer Treatment
    Kangkang Li, Kuiwu Ren, Sen Du, Xiang Gao, Jiangtao Yu · 2024 · Technology in Cancer Research & Treatment
  25. Organoid technology in cervical cancer research
    Hui Ye · 2025 · American Journal of Cancer Research
  26. Immune and Immune‐Integrated Organoids as NextGeneration Platforms for Disease Modeling
    Kimiya Rashidan, Malaksima Ayadilord, Ali Hazrati, Amirhossein Nazerian, Abbas Shafiee, Seyed Mahmoud Hashemi · 2025 · MedComm
  27. Progress in patient-derived liver cancer cell models: a step forward for precision medicine
    Zhengtao Zhang, Lijian Hui · 2023 · Acta Biochimica et Biophysica Sinica
  28. Interferon-β Overexpression in Adipose Tissue-Derived Stem Cells Induces HepG2 and Macrophage Cell Death in Liver Tumor Organoids via Induction of TNF-Related Apoptosis-Inducing Ligand Expression
    Yongdae Yoon, Chang Wan Kim, Moon Young Kim, Soon Koo Baik, Pil Young Jung, Young Woo Eom · 2024 · International Journal of Molecular Sciences
  29. Patient-derived organoid models to decode liver pathophysiology
    Benjamin J. Dwyer, Janina E. E. Tirnitz‐Parker · 2024 · Trends in Endocrinology and Metabolism
  30. Adenosine Receptor 3 in Liver Cancer: Expression Variability, Epigenetic Modulation, and Enhanced Histone Deacetylase Inhibitor Effects
    Louise Kaldjob-Heinrich, Sandro Nuciforo, Steffen Lemke, Aaron Stahl, Stefan Czemmel, Sepideh Babaei, Lauriane Blukacz, Marie‐Anne Meier, Yizheng Zhang, Christian M. Schürch et al. · 2024 · Gastro Hep Advances
  31. Miniaturization and characterization of patient derived hepatocellular carcinoma tumor organoid cultures for cancer drug discovery applications
    David A. Close, Paul A. Johnston · 2024 · SLAS discovery : advancing life sciences R & D
  32. Using organoid models to predict chemotherapy efficacy: the future of precision oncology?
    Steven Donald Forsythe, Tracey Pu, Aleksander Skardal · 2019 · Expert Review of Precision Medicine and Drug Development
  33. Organoid transduction using recombinant adeno‐associated viral vectors: Challenges and opportunities
    Lyubava Belova, А. В. Лавров, Svetlana Smirnikhina · 2022 · BioEssays
  34. Conversion therapy in advanced perihilar cholangiocarcinoma based on patient-derived organoids: A case report
    Yonggang He, Lingyu Zhang, Jing Li, Zheng Wang, Chong-Yu Zhao, Lu Zheng, Xiaobing Huang · 2024 · World Journal of Gastrointestinal Oncology
  35. Modelling hepatocellular carcinoma microenvironment phenotype to evaluate drug efficacy
    Sara Cherradi, Salomé Roux, Marie Dupuy, Séverine Tabone‐Eglinger, Édouard Tuaillon, Marianne Ziol, Eric Assénat, Hong Tuan Duong · 2025 · Scientific Reports
  36. The IL-6/JAK/STAT3 Axis in Cholangiocarcinoma and Primary Sclerosing Cholangitis: Unlocking Therapeutic Strategies Through Patient-Derived Organoids
    Corinna Boden, Laura Kristin Esser, Leona Dold, Bettina Langhans, Taotao Zhou, Dominik J. Kaczmarek, Maria Angeles Gonzalez-Carmona, Tobias J. Weismüller, Glen Kristiansen, Jörg C. Kalff et al. · 2025 · Biomedicines
  37. EUS-guided fine-needle technique facilitates the establishment of organoid biobanks
    Siyu Sun, Fan Yang, Sheng Wang, Jintao Guo, Xiang Liu, Nan Ge, Guoxin Wang · 2020 · Endoscopic Ultrasound
  38. Genomic evolutionary trajectory of metastatic squamous cell carcinoma of the lung
    Arthur Krause, Luca Roma, Thomas Lorber, Tanja Dietsche, Valeria Perrina, David Christian Müller, Didier Lardinois, Christian Felipe Ruiz, Spasenija Savic Prince, Salvatore Piscuoglio et al. · 2021 · Translational Lung Cancer Research
  39. Isolated cancer stem cells from human liver cancer: morphological and functional characteristics in primary culture
    M. Hu, M. Li, Huichao Huang, Caijie Lu · 2021 · Clinical & Translational Oncology
  40. Review: Challenges of In Vitro CAF Modelling in Liver Cancers
    Alba Herrero, Elisabeth Knetemann, Inge Mannaerts · 2021 · Cancers
  41. Evaluation of Radiation Sensitivity Differences in Mouse Liver Tumor Organoids Using CRISPR/Cas9-Mediated Gene Mutation
    Wan Jeon, Se Yeon Jung, Chae Young Lee, Won‐Tae Kim, Hyun Kim, Kyoung Won Jang, Heuijin Lim, Manwoo Lee, Dong Hyeok Jeong, Sung‐Dae Kim et al. · 2023 · Technology in Cancer Research & Treatment
  42. Modeling Tumor Heterogeneity in Bladder Cancer: The Current State of the Field and Future Needs
    Amanda K. Seyer, Heather L. Lehman, David J. DeGraff · 2019 · Bladder Cancer
  43. Novel 3D preclinical model systems with primary human liver cells: Recent progresses, applications and future prospects
    Jiangang Zhang, Huayu Yang, Yilei Mao · 2021 · Hepatobiliary & pancreatic diseases international
  44. Review on Advanced Cancer Modeling for a Cancer Study
    Yong‐Hee Cho · 2022 · Current Issues in Molecular Biology
  45. Reconstructing the hepatocellular carcinoma microenvironment: the current status and challenges of 3D culture technology
    Ting Xiong, Kai Wang · 2025 · Discover Oncology
  46. Establishment of a mouse hepatocellular carcinoma tumoroid panel recapitulating inter- and intra- heterogeneity for disease modelling and combinatorial drug discovery
    Margherita Grattarola, Nicolas Pons, Floriane Cannet, Müge Kaya, Abdessamad El Kaoutari, C. Morel, Aurélie Dobric, Jean‐Paul Borg, Celia Sequera, Flavio Maina · 2025 · Cell Communication and Signaling
  47. Unraveling the impact of AXIN1 mutations on HCC development: Insights from CRISPR/Cas9 repaired AXIN1-mutant liver cancer cell lines
    Ruyi Zhang, Shanshan Li, Kelly Schippers, Boaz Eimers, Jiahui Niu, Bastian Hornung, Mirjam C. G. N. van den Hout, Wilfred F. J. van IJcken, Maikel Petrus Peppelenbosch, Ron Smits · 2024 · PLoS ONE
  48. Assessment of the in vitro cytochrome P450 activity in human liver organoids: Development and validation of a cocktail method with liquid chromatography–tandem mass spectrometry
    Guofang Bi, Shi Li, Qingqing Yu, Ye Liang, Peng Wang, Jiayin Guo, Yang Xiao, Shuqin Zhou, Jian-Hong Fang, Qing Peng et al. · 2025 · Drug Metabolism and Disposition
  49. Establishment and characterization of a new Chinese hepatocellular carcinoma cell line, Hep-X1
    Hao Xu, Xin Miao, Changpeng Chai, Huan Tang, Jinjing Hu, Zhenjie Zhao, Wei Luo, Kexiang Zhu, Wence Zhou · 2022 · Human Cell
  50. Physiologically relevant microsystems to study viral infection in the human liver
    Dennis McDuffie, David Barr, Ashutosh Agarwal, Emmanuel Thomas · 2022 · Frontiers in Microbiology
  51. Cellular therapies in liver and pancreatic diseases
    Lucia Giuli, Francesco Santopaolo, Maria Pallozzi, Antonio Pellegrino, Gaetano Coppola, Antonio Gasbarrini, Francesca Romana Ponziani · 2022 · Digestive and Liver Disease
  52. Chloroquine diphosphate suppresses liver cancer via inducing apoptosis in Wistar rats using interventional therapy
    Xiaoguang Hao, Weijing Li · 2021 · Oncology Letters
  53. Proteogenomic characterization of hepatocellular carcinoma
    Charlotte K.Y. Ng, Eva Dazert, Tuyana Boldanova, Mairene Coto‐Llerena, Sandro Nuciforo, Caner Ercan, Aleksei Suslov, Marie-Anne Meier, Thomas Bock, Alexander Schmidt et al. · 2021 · bioRxiv (Cold Spring Harbor Laboratory)
  54. The application of liver cancer organoids in tumour precision medicine: A comprehensive review
    Jiaye Mo, Da Gong, Mei Zhai, Jintao Yang, Zhike Li, Meilong Wu, Xuesong Deng, Xiaoyong Dai · 2025 · iLiver
  55. Establishment of Patient-Derived Organoids from Hepatocellular Carcinoma: Preliminary Data on Yield, Histopathological Concordance, and Methodological Challenges
    Oriana Lo Re, Christian Corti, Lucia Cerrito, Eleonora Cesari, Elisabetta Creta, Flavio De Maio, Alessia Di Prima, Vincenzo Facciuto, Clelia Ferraro, Eleonora Huqi et al. · 2026 · Cells
  56. Generation of Organoids and Analysis of Ferroptosis in Organoids
    Wenxin Li, Yujie Su, Jingyi Guo, Mengfei Wang, Xingguo Liu · 2023 · Methods in molecular biology
  57. Global landscape of hepatic organoid research: A bibliometric and visual study
    Tao Li, Rongqiang Bo, Jun Yan, Nadia L. Johnson, Meng-Ting Liao, Yuan Li, Yan Chen, Jie Lin, Jian Li, Fuhao Chu et al. · 2025 · World Journal of Hepatology
  58. Progress of 3D Organoid Technology for Preclinical Investigations: Towards Human In Vitro Models
    Yingjuan Liu, Honglin Xu, Sabu Abraham, Xin Wang, Bernard D. Keavney · 2022 · International Journal of Drug Discovery and Pharmacology
  59. Patient-derived functional organoids as a personalized approach for drug screening against hepatobiliary cancers
    Ling Li, Florin M. Selaru · 2022 · Advances in cancer research
  60. Studying Hepatitis Virus-Host Interactions in Patient Liver Biopsies
    Aleksei Suslov, Markus Hermann Heim, Stefan F. Wieland · 2022 · Viruses
  61. Technological Advancement in Cancer Stem Cell Research
    Tanu Sharma, Chandi Charan Mandal · 2020 · Springer eBooks
  62. A new proposal of an ultrasonic imaging model for predicting overall and progression-free survival in patients with primary hepatocellular carcinoma
    Xiaoyun Li, People’s Republic of China, Lin-lin Wang · 2022 · Diagnostic and Interventional Radiology
  63. Generation and characterization of feline colorectal adenocarcinoma organoids as a preclinical model
    Ami Kanaya, Rina Nabeta, Ting-Wei YU, Haru Yamamoto, Yishan LIU, Amira Abugomaa, Mohamed Elbadawy, Kazuya Shimoda, Tatsuya Usui, Tsuyoshi Uchide · 2025 · Journal of Veterinary Medical Science
  64. Liver-Specific Extracellular Matrix Enables High-Fidelity Patient-Derived Hepatocellular Carcinoma Xenograft Models
    Su Kyeom Kim, Jung‐Ho Bae, Mi Jeong Lee, Dai Hoon Han, Seung‐Woo Cho · 2025 · Biomaterials Research
  65. Patient-derived organoids as a model to study tubo-ovarian carcinoma: a pathologist’s perspective
    Catarina Alves‐Vale, Beatriz Galvão, Ana Rita Silvestre, José Silva Pereira, Li Bei, João Paulo Fernandes, Paula Borralho, Maria Carmo‐Fonseca, Noélia Custódio · 2025 · Journal of Ovarian Research
  66. Next-Generation Hydrogels for Biliary Organoid Engineering
    Andrea Marfoglia, Giovanni Sorrentino · 2025 · Pharmaceuticals
  67. D-amino acid oxidase suppresses hepatocellular carcinoma via oxidizing D-amino acids
    Zishuai Li, Chao Fu, Yifan Chen, Letian Fang, Wenbin Liu, Jun Zhao, Jiayi Zhao, Ran Meng, Rui Pu, Yiwei Shi et al. · 2025 · Journal of Translational Medicine
  68. Patient-derived tumor organoids for new drug development: promises and challenges
    Meijun He, Ying Wu, Furong Du, Jingrui Wang, Honghan Zhang, Jian Han · 2026 · Investigational New Drugs
  69. Drug resistance mechanisms of immunotherapy and translational strategies for reversing resistance for hepatocellular carcinoma: from bench to bedside
    Chenfang Zhang, Dan Zhang, Xin Wen, Shui Liu · 2026 · Frontiers in Immunology
  70. Insights From Spatiality: Accelerating Pharmaceutical Research Using Mass Spectrometry Imaging
    Yuchen Zou, Zhiye Yan, Weiwei Tang, Bin Li · 2026 · Medicinal Research Reviews
  71. New and effective method to develop primary hepatocytes from liver cancer patients
    Jiayan Li, Lili Wang, Jing Fan, Du-Xian Liu, Jianbo Han, Yufeng Zhang, Dandan Yin, Yongxiang Yi · 2022 · Experimental Biology and Medicine
  72. Tuning the structure and properties of cell-embedded gelatin hydrogels for tumor organoids
    Sarah Oliveira Lamas de Souza, Sérgio Mendes de Oliveira, Catarina Paschoalini Lehman, Mercês Coelho da Silva, Luciana Maria Silva, Rodrigo Lambert Oréfice · 2023 · Polímeros
  73. Histidine-tagged dialdehyde cellulose nanoparticles to study the co-treatment effect of curcumin and 3-methyladenine on HepG2 cells
    Sheyda Sharifi, Effat Alizadeh, Sevil Vaghefi Moghaddam, Fereshteh Rahdan, Roya Herizchi, Leila Alidoust, Parvaneh Keshavarz · 2025 · Carbohydrate Polymer Technologies and Applications
  74. Construction of a metastasis model for liver cancer spheroids to hepatobiliary organoids facilitated by holographic acoustic tweezers
    Jialong Li, Dingyuan Liu, Zeping Gao, Mengting Sun, Shuo Wang, Lihong Zhang, Ye Yang, Hongyu Wang, Hairong Zheng, Ye Tian et al. · 2025 · Cell Reports Physical Science
  75. Diagnostic accuracy and Patient Derived Organoid (PDO) yield of 19G vs 22G Franseen needles for EUS-Guided biopsy in solid pancreatic lesions: A prospective comparative study
    Sarah Klauss, Yonggan Xue, Ahmed Alnatsha, Prince Allawadhi, Ujjwal Mukund Mahajan, Elisabetta Goni, Marlies Vornhülz, Simon Sirtl, Christian Schulz, Mark op den Winkel et al. · 2025 · Pancreatology
  76. Biofabrication of advanced in vitro and ex vivo cancer models for disease modeling and drug screening
    Kylie G. Nairon, Aleksander Skardal · 2021 · Future Drug Discovery
  77. Liver stem cells
    Dagmara Szkolnicka, David C. Hay · 2020 · Elsevier eBooks
  78. An organoid-guided platform for ovarian cancer: enabling prediction of patients’ chemotherapy response
    Ling Wang, Misi He, Xueping Zhu, Lifang Ma, Lin Zhong, Qingxiu Jiang, Qiaoling Li, Hongji Wu, Haixia Wang, Dongling Zou · 2026 · Journal of Ovarian Research
  79. Advanced strategies in organoids for metabolic monitoring and metabolic disease modeling
    Wenjun Ma, Yongxin Xu, Zhifeng Gu, Dong Li · 2025 · Nano Research
  80. Design and sensitivity investigation of a rectangular pocket based dopingless TFET biosensor for liver cancer detection
    Shwetapadma Panda, Sidhartha Dash · 2025 · Microsystem Technologies
  81. Cellulose microfiber-mediated mesoscale architecture promotes the expansion of patient-derived lung cancer organoids while preserving their malignant characteristics
    Chengjing Zhou, Jiaxin Wang, Yongming Zhang, Ziyuan Zhou, Chuanyue Wu, Lühua Wang, Ling Guo · 2025 · Journal of Materials Chemistry B
  82. Patient-Derived Cancer Organoids: Standardized Protocols for Tumor Cell Isolation, Organoid Generation, and Serial Passaging Across Multiple Cancers
    Ali Şahin, Dila Sener-Akcora, Ayşe Mine Yılmaz, Muharrem Okan Çakır, Betul Karademir-Yilmaz · 2025 · Methods in molecular biology
  83. ꞵ-Cu2V2O7/Cs NIR (II) responsive nanocomposite for synergistic chemodynamic/photothermal therapy with multi-modal imaging in hepatocellular carcinoma
    Kayalvizhi Samuvel Muthiah, Sathan Raj Natarajan, Selvaraj Jayaraman, Yu‐Chien Lin, Udesh Dhawan, Ren‐Jei Chung · 2025 · Biomaterials Advances
  84. Organoid models in viral hepatitis, primary liver cancer, and non-alcoholic fatty liver disease: Advances and challenges
    Ya-Qin Han, Yunyang Xu, Ze Xiang, Qiu-Fang Xu, Fei Gao, Mei-Na Yan, Jian Wu · 2026 · Hepatobiliary & pancreatic diseases international
  85. The Novel HSF1 Inhibitor NXP800 Exhibits Robust Antitumor Activity in Hepatocellular Carcinoma
    Sara Martina Steinmann, Melania Lazzari, Augustinus Kleinle, Dora Pischedda, Antonio Cigliano, Grazia Galleri, Heiko Ingo Siegmund, Claudia Fischer, Salvatore Piscuoglio, Matthias Evert et al. · 2026 · International Journal of Molecular Sciences
  86. Patient-Derived Organoid Modeling of Glypican-3 CAR-T Responses in Hepatocellular Carcinoma
    B Zhang, Yun Deng, Mingshan Zhou, Junfei Chen, Jiawen Wu, Xiaofeng Lian, Min Zhou, Min Zhou, Jie Cao · 2026 · Cells
  87. A review of organoid–immune co-culture platforms to model the immune microenvironment of hepatocellular carcinoma and guide immunotherapy
    Wen-Wen Liu, Xi-Shuai Xie, Xiao-Jun Yang · 2026 · Journal of Translational Medicine
  88. Patient-Derived Organoids in Clinical Medicine: Proven Impact and Future Directions
    Magdalena Skowrońska, Ece Yıldız, Jens Grosch, Mairene Coto‐Llerena · 2026 · Organoids
  89. Inhibition of PERK signaling suppresses tumor progression and blocks GP73-GRP78-dependent stromal activation in hepatocellular carcinoma
    Jaafar Khaled, Maria Kopsida, Tania Payo‐Serafín, Sofi Sennefelt Nyman, Fredrik Rorsman, Charlotte Ebeling Barbier, Hans Lennernäs, Markus Sjöblom, Femke Heindryckx · 2026 · Neoplasia
  90. Patient-derived organoids in functional precision oncology: from experimental models to clinical decision-making
    Amanda Caruso, Antonella Delvecchio, Riccardo Memeo, Marilena Lanzino, S Martinotti · 2026 · Frontiers in Endocrinology
  91. Hepatocellular carcinoma organoids enable drug discovery and combination therapy across heterogeneous tumors
    Sandro Nuciforo, Lauriane Blukacz, Marie-Anne Heusler, Tijmen H. Booij, Lukas Kübler, Fredrik Trulsson, Tuyana Boldanova, Xueya Wang, Sylvia Ketterer, Matthias S. Matter et al. · 2026 · Cell Reports
  92. Liver Tissue Engineering
    Sara Morini, Natalia Sánchez‐Romero, Iris Plá-Palacín, P Arnal, Manuel Barbosa de Almeida, Laurens F. M. Verscheijden, Joana I. Almeida, Alberto Luè, Sara Llorente, Helen Almeida et al. · 2018 · CRC Press eBooks
  93. Advances and applications in liver organoid technology
    Li Lin, Miao LEI, JiaMan LIN, Wenxiang Hu · 2021 · Scientia Sinica Vitae
  94. Development and Optimization of A Human Hepatocellular Carcinoma Patient-Derived Organoid Model for Potential Target Identification and Drug Discovery
    Chengyang Zhang, Xiao-Feng Zhang, Jun Yuan, Yuanfeng Gong, Hui Tang, Wan-Yu Guo, T. Li, Caiwen Li, Yunqiang Tang, Ning‐Fang Ma et al. · 2023 · Journal of Visualized Experiments
  95. A Hepatocellular Cancer Patient-derived Organoid Xenograft Model to Investigate Impact of Liver Regeneration on Tumor Growth
    Fabian Haak, Gabriel Fridolin Hess, Philip Sedlaczek, Savas Deniz Soysal, Jürg Vosbeck, Salvatore Piscuoglio, Mairene Coto‐Llerena, Otto Kollmar · 2024 · Journal of Visualized Experiments
  96. Practical Applications of 3D Cell Culture Biotechnologies for Translational Oncology and Personalized Therapy
    Daria A. Chudakova, E. Skorova, Igor V. Reshetov · 2020 · Biotekhnologiya
  97. Application and research progress of in vitro liver cancer cell culture models
    Jiali Xing, Yuxin Wang, Shunda Du · 2021 · World Chinese Journal of Digestology
  98. Liver Tissue Engineering
    Iris Plá-Palacín, Natalia Sánchez‐Romero, Sara Morini, Daniela Rubio-Soto, Pedro M. Baptista · 2020 · Springer eBooks
  99. Liver Tissue Engineering
    Iris Plá-Palacín, Natalia Sánchez‐Romero, Sara Morini, Daniela Rubio-Soto, Pedro M. Baptista · 2021 · Reference series in biomedical engineering
  100. The Role of Tumoroids in Cancer Research
    Mahsa Yousefpour Marzbali, Nima Rezaei · 2023 · Interdisciplinary cancer research