TP63-Mediated Enhancer Reprogramming Drives the Squamous Subtype of Pancreatic Ductal Adenocarcinoma

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1. Additional file 2 of ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
   Eleftheria Vasilaki, Yu Bai, Mohamad Moustafa Ali, Anders Sundqvist, Aristidis Moustakas, Heldin, Carl-Henrik · 2024 · Figshare
2. Additional file 3 of ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
   Eleftheria Vasilaki, Yu Bai, Mohamad Moustafa Ali, Anders Sundqvist, Aristidis Moustakas, Heldin, Carl-Henrik · 2024 · Figshare
3. Additional file 3 of Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis
   Kim, Seongryong, Galam Leem, Junjeong Choi, Yongjun Koh, Lee, Suho, Nam, Sang-Hee, Jin Su Kim, Chan Hee Park, Hwang, Ho Kyoung, Min, Kyoung Il et al. · 2024 · Figshare
4. Additional file 1 of ΔNp63 bookmarks and creates an accessible epigenetic environment for TGFβ-induced cancer cell stemness and invasiveness
   Eleftheria Vasilaki, Yu Bai, Mohamad Moustafa Ali, Anders Sundqvist, Aristidis Moustakas, Heldin, Carl-Henrik · 2024 · Figshare
5. Additional file 1 of TP63–TRIM29 axis regulates enhancer methylation and chromosomal instability in prostate cancer
   Султанов Ринат Илгизович, A. Mulyukina, Olga A. Zubkova, A. Fedoseeva, Alexandra Bogomazova, Klimina, K., Larin, A., Timofei S. Zatsepin, T. A. Prikazchikova, Lukina, M. et al. · 2024 · Figshare
6. Additional file 2 of Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis
   Kim, Seongryong, Galam Leem, Junjeong Choi, Yongjun Koh, Lee, Suho, Nam, Sang-Hee, Jin Su Kim, Park, Chan Hee, Hwang, Ho Kyoung, Min, Kyoung Il et al. · 2024 · Figshare
7. Mapping cellular heterogeneity and dynamic interactions in pancreatic cancer
   Tatekalva Sandhya, Seema Kumari, Meghapriya Adem, V. K. Chaithanya Manam, Ganji Purnachandra Nagaraju, Mundla Srilatha · 2026 · Journal of Controlled Release
8. The role of histone modifications in the regulation of alternative splicing during epithelial-to-mesenchymal transition
   Alexandre Segelle · 2020 · theses.fr (ABES)
9. Cell-free chromatin epigenomic profiling enables non-invasive pancreatic cancer cell-state identification
   Karl Semaan, Marc Eid, Damien Vasseur, Gunsagar Singh Gulati, Cibelle Freitas Pinto Lima, Élio Ibrahim, Ji-Heui Seo, John Canniff, Hunter Savignano, Alexander C. Jordan et al. · 2026 · medRxiv
10. Chimiorésistance du cancer du pancréas : rôle de la transition épithéliomésenchymateuse et les voies de signalisation impliquées
    Mehdi El Amrani · 2019
11. Isoform-specific cofactor recruitment through the intrinsically disordered N-terminus of p63 underlies differential transcriptional activities
    Marina F. Nogueira, Michael J. Moore, Aparna Riti Biswas, Michael P. Meers, Sidharth V. Puram · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
12. Twist1 overexpression models an aggressive subtype of pancreatic ductal adenocarcinoma in vivo
    Muhammad Ajmal Khan, Jinhee Chang, Yang Song, Amol Carl Shetty, Triet Nguyen, Danielle N. Waters, Dipanwita D. Chowdhury, Elan R. Simms, Aaron Chan, Hwai Wei Tseng et al. · 2026 · Lab Animal
13. GATA4 loss promotes mutant Kras -driven pancreatic ductal adenocarcinoma in the absence of canonical precursor lesions
    Francesc Madriles, Mónica P. de Andrés, Mikhail Chesnokov, Jaime Martínez de Villarreal, Direna Alonso‐Curbelo, Natalia del Pozo, Mar Iglesias, Enrique Carrillo de Santa Pau, Juan Iovanna, Francisco Soriano et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
14. KMT2D depletion promotes KRAS-induced pancreatic carcinogenesis independent of TP53
    Ezequiel J Tolosa, G. L. Raja Arul, Ashley N. Sigafoos, Victoria Ferrero, David R. Pease, Luciana L. Almada, Renzo E Vera, Nicole M. Pena Ruiz, Tara L. Hogenson, Kayla C. LaRue-Nolan et al. · 2026 · Journal of Biological Chemistry
15. Luminal–basal stratification of the native human pancreatic duct is differentially represented in pancreatic cancers
    Jan-Lars Van den Bossche, Melissa Van der Vliet, Ellis Michiels, Oier Azurmendi Senar, Silke Van Lint, Zeynep Madran, Katarina Coolens, Jack Brons, Montserrat Nacher, Tatjana Arsenijevic et al. · 2026 · Gut
16. Clinical, Genomic, and Spatial Transcriptomic Features of Pancreatic Adenosquamous Carcinoma Support Subtype-Specific Therapeutic Strategies
    Saurav Daniel Haldar, Meredith Wetzel, Jiayun Lu, Jae Woo Lee, Hassan Sinan, Christopher Dennis Jakubowski, Fen Saj, Dean C. Pavlick, Ryon P. Graf, Júlia C.F. Quintanilha et al. · 2026 · Clinical Cancer Research
17. Continuous tissue fields organize immune composition in pancreatic cancer
    Weihao Wang, Shayan Sarkar, Marie C. Hasselluhn, Nicole Lui-Leung, Lyanne Delgado Coka, Despina Siolas, Н. В. Марченко, Luisa F. Escobar‐Hoyos, Mikala Egeblad, Mara H. Sherman et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
18. The Classical–Basal Spectrum in Pancreatic Ductal Adenocarcinoma: A Developmental Framework for Tumour Cell Plasticity and Clinical Translation
    Ikra Khan, Azzadinne Belhaj, Alessandro Gemini, Kenza Azra Ibis, Nouman Darsif, Najoua Rouani, Aude Vanlander, Nouredin Messaoudi · 2026 · Cancers
19. Organoid-based in vitro–in vivo extrapolation: approaches to intestinal, hepatic, and brain pharmacokinetic prediction
    Eunseo Jung, Hyeon-Cheol Jeong, Kyeong-Ryoon Lee · 2026 · Organoid
20. Heterogeneous growth responses of pancreatic ductal adenocarcinoma organoids to exogenous Wnt supplementation: an in vitro experimental study in Korea
    Yanghee Choi, Eun Joo Lee, Da Hee Oh, Hyeji Kim, Sang Myung Woo, Jung Won Chun, Sun‐Young Kong · 2026 · Organoid
21. IRE1α–XBP1s signaling links lipid homeostasis to hypoxic maladaptation and KRAS inhibitor responses in pancreatic ductal adenocarcinoma
    Yanqing Jiang, Cassidy Pagen, Gusangyu Yin, Zian Zhang, Mai Wang, Carson D. Poltorack, Yizheng Xue, Xu Han, Nathan J. Coffey, Morgan Brown et al. · 2026 · Proceedings of the National Academy of Sciences
22. p63 and p73 drive cutaneous squamous cell carcinoma through convergent transcriptional control of EGFR signaling
    Dario Antonini, Marco Ferniani, Sara Palumbo, Marco Franciosi, Daniela Di Girolamo, Claudia Russo, Ludovica D’Auria, 曲洁琼, Andrew P. South, Gernot Walko et al. · 2026 · Cell Reports
23. Epigenetic progression of pancreatic cancer to aggressive subtypes involves alternate routes of lineage reprogramming in subtype-intermediate progenitor cells
    Kevin Hawthorne, Jennifer R. Eng, Motoyuki Tsuda, Patrick Joseph Worth, Andrew J. Fields, Colin J. Daniel, Andrew Nishida, Carl Pelz, Ellen M. Langer, Trent Waugh et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
24. Transcription factor-driven metabolic stratification reveals glycolytic and lipogenic subtypes with distinct prognostic and functional features in pancreatic cancer
    Jie Ke, Shuai Liu, Junming Xu, Fenfang Wu · 2026 · Frontiers in Oncology
25. HMGA2 Expression in Pancreatic Ductal Adenocarcinoma Controls Tumor Microenvironment and Immunosuppression via IL1α
    Naomi Yamamoto, Stephanie Dobersch, Tess M. Robertson, Jae Hyung Sim, Adrianne Wallace-Povirk, Nayvin W. Chew, Alexander E. Orellana, Joana E. Aggrey-Fynn, Liberalis Debraj Boila, Aidan Schutter et al. · 2026 · bioRxiv (Cold Spring Harbor Laboratory)
26. Basal Marker ΔNp63α Is Enriched in Pancreatic Cancer Metastases but Not in Primary Tumors Post‐Chemotherapy
    Daniel H. Ryan, Yuuki Ohara, Michael J. Kruhlak, Xianyu Zhang, Miao Lin, Chin‐Hsien Tai, Christine Alewine · 2026 · Cancer Medicine
27. Context-Dependent Spatial and Functional Roles of CD44 Across Pancreatic Ductal Adenocarcinoma States
    Bin Fu, Yingying Tan, Yaxin Chen, Yongren Su, Mengran Cao, Dashan Tan, Meng Zhang, Xuewei Chen, Rong Hu · 2026 · Cancers
28. Integrative analysis of spatial and single-cell transcriptome data from human pancreatic cancer reveals an intermediate cancer cell population associated with poor prognosis_Spatial H&E images
    Seongryong Kim, Leem Galam, Junjeong Choi, Jong-Eun Park, Chang Moo Kang, Seungmin Bang · 2024 · Zenodo (CERN European Organization for Nuclear Research)