Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia

Bernier, Louis-Philippe, Bohlen, Christopher J., York, Elisa M., Choi, Hyun B., Kamyabi, Alireza, Dissing-Olesen, Lasse, Hefendehl, Jasmin K., Collins, Hannah Y. +3 more·2019·Cell Reports

Cited by (214)

Items 101–200 of 214

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  4. Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defects
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  5. Inhibition of Na + /H + exchanger modulates microglial activation and scar formation following microelectrode implantation
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  7. Chemogenetic activation of microglial Gi signaling decreases microglial surveillance and impairs neuronal synchronization
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  10. Mitochondria are absent from microglial processes performing surveillance, chemotaxis, and phagocytic engulfment
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  11. Ultrastructural analysis of the morphological phenotypes of microglia associated with neuroinflammatory cues
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  12. Chemogenetic manipulation of CX3CR1+ cells transiently induces hypolocomotion independent of microglia
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  13. KRIBB11: A Promising Drug that Promotes Microglial Process Elongation and Suppresses Neuroinflammation
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  14. Versatile Surface Electrodes for Combined Electrophysiology and Two-Photon Imaging of the Mouse Central Nervous System
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  15. Microglia at the Centre of Brain Research: Accomplishments and Challenges for the Future
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  16. Control of microglial dynamics by Arp2/3 and the autism and schizophrenia-associated protein Cyfip1
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  17. Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficits
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  18. Microglial reprogramming by Hv1 antagonism protects neurons from inflammatory and glutamate toxicity
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  19. Exploring the Significance of Microglial Phenotypes and Morphological Diversity in Neuroinflammation and Neurodegenerative Diseases: From Mechanisms to Potential Therapeutic Targets
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  20. Wasl is crucial to maintain microglial core activities during glioblastoma initiation stages
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  22. Morphofunctional programming of microglia requires distinct roles of type II myosins
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  23. The effect of morphine on rat microglial phagocytic activity: An in vitro study of brain region-, plating density-, sex-, morphine concentration-, and receptor-dependency
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  24. P2Y12 Receptor Function Governs Microglial Surveillance and Cell–Cell Interactions in the Cerebral Cortex
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  25. Microglial Metamorphosis in Three Dimensions in Virus Limbic Encephalitis: An Unbiased Pictorial Representation Based on a Stereological Sampling Approach of Surveillant and Reactive Microglia
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  28. Emerging non-proinflammatory roles of microglia in healthy and diseased brains
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  33. A unique role for cAMP signaling in microglia during opioid tolerance and withdrawal
    Kevin R. Coffey, John F. Neumaier · 2023 · Neuropsychopharmacology
  34. Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 Mice
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  35. Microglial states revisited: from homeostasis to disease
    Eggen, Bart J. L., Kooistra, Susanne M. · 2026 · Nature Reviews Neuroscience
  36. Profilin 1 controls a microglial cytoskeleton checkpoint to prevent senescence and premature synaptic decline
    Camila Cabral Portugal, Tiago Oliveira Almeida, Joana Tedim-Moreira, Cátia Silva, Teresa Canedo, João Galvão, Ana Magalhães, Teresa Summavielle, Xianshu Bai, Frank Kirchhoff et al. · 2025 · Journal of Neuroinflammation
  37. The effects of P2Y12 loss on microglial gene expression, dynamics, and injury response in the cerebellum and cerebral cortex
    Mark B. Stoessel, Rianne D. Stowell, Rebecca L. Lowery, Linh Le, Andy N. Vu, Brendan S. Whitelaw, Ania Katarzyna Majewska · 2024 · Brain Behavior and Immunity
  38. Brain region and sex differences in human microglia morphology and function
    Andrew R. Yoblinski, Jyoti Dubey, Tyler Myers, Nitya Sathees, David W. Volk, Kenneth N. Fish, Marianne L. Seney · 2025 · Cerebral Cortex
  39. Microglial low-affinity FcγR mediates the phagocytic elimination of dopaminergic neurons in Parkinson’s disease degeneration
    Paola V. Casanova, Irina Freitag-Berenguel, Elena Saavedra-López, M. Usandizaga-Estarloa, C. Ríos-Cuadrado, P. Martínez-Remedios, Claudia Gimenez-Montes, Elsa Clinton, Meritxell Roig-Martínez, George Paul Cribaro et al. · 2026 · npj Parkinson s Disease
  40. p27kip1 Modulates the Morphology and Phagocytic Activity of Microglia
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  42. Amyloid plaques and normal ageing have differential effects on microglial Ca2+ activity in the mouse brain
    Pablo Izquierdo, Renaud Jolivet, David Attwell, Christian Madry · 2023 · Pflügers Archiv - European Journal of Physiology
  43. RNA-binding protein IMP1/ZBP1 directs local translation in microglial processes to regulate motility and phagocytosis during inflammation
    Josune Imaz-Iruretagoyena, Maite Blanco‐Urrejola, Irene Núñez-García, Irene García-Toledo, Luis C. Fernández-Beltrán, Mar Márquez, Silvia Corrochano, Amanda Sierra, Jimena Baleriola · 2025 · PLoS Biology
  44. The role of glial cells in amyotrophic lateral sclerosis
    Virenkumar A. Pandya, Rickie Patani · 2024 · International review of neurobiology
  45. Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in mice
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  46. Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic
    Francesca Logiacco, Laura Cathleen Grzegorzek, Elizabeth Cordell, Oliver Popp, Philipp Mertins, David H. Gutmann, Helmut Kettenmann, Marcus Semtner · 2023 · Acta Neuropathologica Communications
  47. Integrative Analysis of Single-Cell and Bulk Sequencing Data Depicting the Expression and Function of P2ry12 in Microglia Post Ischemia–Reperfusion Injury
    Chenglong Wang, Peng Li, Yuan Wang, Ying Xue, Tianyi Chen, Yanyan Ji, Yishan Li, Yong Mei Zhao, Shanshan Yu · 2023 · International Journal of Molecular Sciences
  48. ER and SOCE Ca2+ signals are not required for directed cell migration in human iPSC-derived microglia
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  49. Microglia Regulate Sleep via Calcium-Dependent Modulation of Norepinephrine Transmission
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  50. Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory
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  51. Adrenergic Control of P2Y6 Receptor‐Dependent Phagocytosis in Rodent and Human Microglia
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  53. Targeting microglia microtubules: cytoskeletal remodeling as a druggable hub in neuroinflammation and neurodegeneration
    Caterina Sanchini, Maria Rosito, Francesca Bartolini, Silvia Di Angelantonio · 2026 · Frontiers in Neuroscience
  54. Tenascin-C fibronectin D domain is involved in the fine-tuning of glial response to CNS injury in vitro
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  55. Sporopollenin exine capsules modulate the function of microglial cells
    Mengwei Li, Banglian Hu, Zhaojie Wu, Ziwei Wang, Jian Huang Weng, Honghua Zheng, Liping Sun · 2023 · Biomaterials Science
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  57. RiboTag-Seq Reveals a Compensatory cAMP Responsive Gene Network in Striatal Microglia Induced by Morphine Withdrawal
    Kevin R. Coffey, Atom J. Lesiak, Russell G. Marx, Emily K. Vo, Gwenn A. Garden, John F. Neumaier · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
  58. Control of microglial dynamics by the Arp2/3 complex and the autism- and schizophrenia-associated protein CYFIP1
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  82. GPCR-targeted imaging and manipulation of homeostatic microglia in living systems
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  83. G179(P) Long Term Follow-Up For Paediatric Oncology Patients at a Paediatric Department of a General Hospital
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  85. To be or not to be?
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  87. Biomaterial-supported MSCs transplantation enhances cell-cell communication for spinal cord injury
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  89. Amyloidosis and ageing have differential effects on microglial Ca 2+ activity in the mouse brain
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  90. The RNA binding protein IMP1/ZBP1 drives mRNA local translation in microglia and mediates polarized migration and phagocytosis in response to inflammation
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  93. Additional file 4 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
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  94. Additional file 3 of Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery
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  100. Additional file 1 of Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsic
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