Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia
Bernier, Louis-Philippe, Bohlen, Christopher J., York, Elisa M., Choi, Hyun B., Kamyabi, Alireza, Dissing-Olesen, Lasse, Hefendehl, Jasmin K., Collins, Hannah Y. +3 more·2019·Cell Reports
Cited by (214)
Items 101–200 of 214
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- Neurofibromatosis 1 - Mutant microglia exhibit sexually-dimorphic cyclic AMP-dependent purinergic defectsNirmeen Elmadany, Francesca Logiacco, Alice Buonfiglioli, Verena Claudia Haage, Elizabeth C. Wright-Jin, Alexander Schattenberg, Roxane M. Papawassiliou, Helmut Kettenmann, Marcus Semtner, David H. Gutmann · 2020 · Neurobiology of Disease
- Inhibition of Na + /H + exchanger modulates microglial activation and scar formation following microelectrode implantationMitchell T. Dubaniewicz, James R. Eles, Stephanie Lam, Shanshan Song, Franca Cambi, Dandan Sun, Steven M. Wellman, Takashi D.Y. Kozai · 2021 · Journal of Neural Engineering
- β-Adrenergic Signaling Promotes Morphological Maturation of Astrocytes in Female MiceMarci F. Rosenberg, Marlesa I. Godoy, Sarah D. Wade, Mercedes F. Paredes, Ye Zhang, Anna Victoria Molofsky · 2023 · Journal of Neuroscience
- Chemogenetic activation of microglial Gi signaling decreases microglial surveillance and impairs neuronal synchronizationShunyi Zhao, Lingxiao Wang, Dimitrios Kleidonas, Fangfang Qi, Yue Liang, Jiaying Zheng, Anthony D. Umpierre, Long‐Jun Wu · 2025 · Science Advances
- Selective agonism of GPR34 stimulates microglial uptake and clearance of amyloid β fibrilsHayato Etani, Sho Takatori, Wenbo Wang, Jumpei Omi, Yusuke Amiya, Aika Akahori, Hirotaka Watanabe, Iki Sonn, Hideyuki Okano, Norikazu Hara et al. · 2025 · Alzheimer s Research & Therapy
- Cilostazol pretreatment prevents PTSD-related anxiety behavior through reduction of hippocampal neuroinflammationMohammad Amin Sadeghi, Sara Hemmati, Hasan Yousefi‐Manesh, Laleh Foroutani, Ehsan Nassireslami, Mojtaba Yousefi Zoshk, Yasaman Hosseini, Kourosh Abbasian, Ahmad Reza Dehpour, Mohsen Chamanara · 2023 · Naunyn-Schmiedeberg s Archives of Pharmacology
- Mitochondria are absent from microglial processes performing surveillance, chemotaxis, and phagocytic engulfmentAlicia N. Pietramale, Xhoela Bame, Megan E. Doty, Kiera E. Schwarz, Robert Hill · 2025 · Nature Communications
- Ultrastructural analysis of the morphological phenotypes of microglia associated with neuroinflammatory cuesEric D. Dyne, Meghan Cawood, Matthew Suzelis, Reagan Russell, Min‐Ho Kim · 2021 · The Journal of Comparative Neurology
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- Versatile Surface Electrodes for Combined Electrophysiology and Two-Photon Imaging of the Mouse Central Nervous SystemMichael Schweigmann, Laura C. Caudal, Gebhard Stopper, Anja Scheller, Klaus Peter Koch, Frank Kirchhoff · 2021 · Frontiers in Cellular Neuroscience
- Microglia at the Centre of Brain Research: Accomplishments and Challenges for the FutureNuno L. Soares, Helena L.A. Vieira · 2021 · Neurochemical Research
- Control of microglial dynamics by Arp2/3 and the autism and schizophrenia-associated protein Cyfip1Drew, James, Arancibia-Carcamo, I. Lorena, Jolivet, Renaud, Lopez-Domenech, Guillermo, Attwell, David, Kittler, Josef T. · 2020
- Cytoskeletal control in adult microglia is essential to restore neurodevelopmental synaptic and cognitive deficitsSofie Kessels, Chloë Trippaers, Melanie Mertens, Ibrahim Hamad, Ben Rombaut, Art Janssen, Keerthana Ramanathan, Sam Duwé, Adelaïde M. Gharghani, Rune Theuwis et al. · 2025 · Science Advances
- Microglial reprogramming by Hv1 antagonism protects neurons from inflammatory and glutamate toxicityDiego Rolando Hernández-Espinosa, Jenna R. Gale, Mia G. Scrabis, Elias Aizenman · 2023 · Journal of Neurochemistry
- Exploring the Significance of Microglial Phenotypes and Morphological Diversity in Neuroinflammation and Neurodegenerative Diseases: From Mechanisms to Potential Therapeutic TargetsMai M. Anwar, Leonor Pérez‐Martínez, Gustavo Pedraza‐Alva · 2024 · Immunological Investigations
- Wasl is crucial to maintain microglial core activities during glioblastoma initiation stagesJulie Mazzolini, Sigrid Le Clerc, Gregoire Morisse, Cédric Coulonges, Jean‐François Zagury, Dirk Sieger · 2022 · Glia
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- Morphofunctional programming of microglia requires distinct roles of type II myosinsPedro Melo, Mariana S. Silveira, Inês Mendes Pinto, João Bettencourt Relvas · 2021 · Glia
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- Microglial Metamorphosis in Three Dimensions in Virus Limbic Encephalitis: An Unbiased Pictorial Representation Based on a Stereological Sampling Approach of Surveillant and Reactive MicrogliaLeonardo Sávio da Silva Creão, João Bento‐Torres, Camila Mendes de Lima, Renata Rodrigues dos Reis, Aline Andrade de Sousa, Zaire Alves dos Santos, José Antônio Picanço Diniz, Daniel Guerreiro Diniz, Cristovam Wanderley Picanço Diniz · 2021 · Brain Sciences
- Partial microglial depletion and repopulation exert subtle but differential effects on amyloid pathology at different disease stagesLinh Le, M. Kerry O’Banion, Ania Katarzyna Majewska · 2024 · Scientific Reports
- Trem2 regulates microglial migratory responses via type I interferon signaling during photoreceptor degenerationJincan He, Wenchuan Zhou, Jing Li · 2025 · Cell Communication and Signaling
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- Folylpolyglutamate synthetase mRNA G-quadruplexes regulate its cell protrusion localization and enhance a cancer cell invasive phenotype upon folate repletionMichal Stark, May Levin, Igor Ulitsky, Yehuda G. Assaraf · 2023 · BMC Biology
- Dendrimer-Conjugated Glutamate Carboxypeptidase II Inhibitor Restores Microglial Changes in a Rabbit Model of Cerebral PalsyNirnath Sah, Zhi Zhang, Alicia Chime, Amanda Fowler, Antonio Mendez-Trendler, Anjali Sharma, Rangaramanujam M. Kannan, Barbara Stauch Slusher, Sujatha Kannan · 2023 · Developmental Neuroscience
- Akkermansia Muciniphila Plays a Neuroprotective Role in HMC3 Cells Through The ‘Gut–Brain’ AxisRong Zou, Guohong Shen, Yixiao Wu, Min Guo, Jun Chen, Sheng Yang, Hongyang Zhao, Huajun Zheng · 2023 · Future Microbiology
- A unique role for cAMP signaling in microglia during opioid tolerance and withdrawalKevin R. Coffey, John F. Neumaier · 2023 · Neuropsychopharmacology
- Early Inhibition of Phosphodiesterase 4B (PDE4B) Instills Cognitive Resilience in APPswe/PS1dE9 MiceBen Rombaut, Melissa Schepers, Assia Tiane, Femke Mussen, Lisa Koole, Sofie Kessels, Chloë Trippaers, Ruben Jacobs, Kristiaan Wouters, Emily Willems et al. · 2024 · Cells
- Microglial states revisited: from homeostasis to diseaseEggen, Bart J. L., Kooistra, Susanne M. · 2026 · Nature Reviews Neuroscience
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- The effects of P2Y12 loss on microglial gene expression, dynamics, and injury response in the cerebellum and cerebral cortexMark B. Stoessel, Rianne D. Stowell, Rebecca L. Lowery, Linh Le, Andy N. Vu, Brendan S. Whitelaw, Ania Katarzyna Majewska · 2024 · Brain Behavior and Immunity
- Brain region and sex differences in human microglia morphology and functionAndrew R. Yoblinski, Jyoti Dubey, Tyler Myers, Nitya Sathees, David W. Volk, Kenneth N. Fish, Marianne L. Seney · 2025 · Cerebral Cortex
- Microglial low-affinity FcγR mediates the phagocytic elimination of dopaminergic neurons in Parkinson’s disease degenerationPaola V. Casanova, Irina Freitag-Berenguel, Elena Saavedra-López, M. Usandizaga-Estarloa, C. Ríos-Cuadrado, P. Martínez-Remedios, Claudia Gimenez-Montes, Elsa Clinton, Meritxell Roig-Martínez, George Paul Cribaro et al. · 2026 · npj Parkinson s Disease
- p27kip1 Modulates the Morphology and Phagocytic Activity of MicrogliaJolien Beeken, Sofie Kessels, Jean‐Michel Rigo, Yeranddy Aguiar Alpizar, Laurent Nguyen, Bert Brône · 2022 · International Journal of Molecular Sciences
- Implications of fractalkine on glial function, ablation and glial proteins/receptors/markers—understanding its therapeutic usefulness in neurological settings: a narrative reviewDeepraj Paul, Duraiswamy Basavan · 2022 · Future Journal of Pharmaceutical Sciences
- Amyloid plaques and normal ageing have differential effects on microglial Ca2+ activity in the mouse brainPablo Izquierdo, Renaud Jolivet, David Attwell, Christian Madry · 2023 · Pflügers Archiv - European Journal of Physiology
- RNA-binding protein IMP1/ZBP1 directs local translation in microglial processes to regulate motility and phagocytosis during inflammationJosune Imaz-Iruretagoyena, Maite Blanco‐Urrejola, Irene Núñez-García, Irene García-Toledo, Luis C. Fernández-Beltrán, Mar Márquez, Silvia Corrochano, Amanda Sierra, Jimena Baleriola · 2025 · PLoS Biology
- The role of glial cells in amyotrophic lateral sclerosisVirenkumar A. Pandya, Rickie Patani · 2024 · International review of neurobiology
- Maternal α-cypermethrin and permethrin exert differential effects on fetal growth, placental morphology, and fetal neurodevelopment in miceBenjamin A. Elser, Benjamin Wen Qing Hing, Samuel Eliasen, Malik A. Afrifa, Naomi Meurice, Farzana Rimi, Michael S. Chimenti, Laura Clamon Schulz, Michael E. Dailey, Katherine Nicole Gibson-Corley et al. · 2025 · Toxicological Sciences
- Neurofibromatosis type 1-dependent alterations in mouse microglia function are not cell-intrinsicFrancesca Logiacco, Laura Cathleen Grzegorzek, Elizabeth Cordell, Oliver Popp, Philipp Mertins, David H. Gutmann, Helmut Kettenmann, Marcus Semtner · 2023 · Acta Neuropathologica Communications
- Integrative Analysis of Single-Cell and Bulk Sequencing Data Depicting the Expression and Function of P2ry12 in Microglia Post Ischemia–Reperfusion InjuryChenglong Wang, Peng Li, Yuan Wang, Ying Xue, Tianyi Chen, Yanyan Ji, Yishan Li, Yong Mei Zhao, Shanshan Yu · 2023 · International Journal of Molecular Sciences
- ER and SOCE Ca2+ signals are not required for directed cell migration in human iPSC-derived microgliaAlberto Granzotto, Amanda McQuade, Jean Paul Chadarevian, Hayk Davtyan, Stefano Luca Sensi, Ian Parker, Mathew M. Blurton-Jones, Ian F. Smith · 2024 · Cell Calcium
- Microglia Regulate Sleep via Calcium-Dependent Modulation of Norepinephrine TransmissionChenyan Ma, Bing Li, Daniel Silverman, Xinlu Ding, Anan Li, Chi Xiao, Ganghua Huang, Kurtresha Worden, Sandra E. Muroy, Wei Chen et al. · 2023 · bioRxiv (Cold Spring Harbor Laboratory)
- Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memorySophie Crux, Marie Denise Roggan, Stefanie Poll, Felix Christopher Nebeling, Juliane Schiweck, Manuel Mittag, Fabrizio Musacchio, Julia Steffen, Katharina M. Wolff, Andrea Baral et al. · 2024 · bioRxiv (Cold Spring Harbor Laboratory)
- Adrenergic Control of P2Y6 Receptor‐Dependent Phagocytosis in Rodent and Human MicrogliaThomas Deluc, Ariel R. Ase, Marie‐France Dorion, Gilles Maussion, Yeman Tang, R J Lo, Irina Shlaifer, Valerio E. C. Piscopo, Thomas M. Durcan, Stefano Stifani et al. · 2025 · Glia
- Glioinflammation: disease-associated microglia and astrocytes in psychiatric disorders, neurodegeneration, and senescenceKumiko Uemura, Shunya Hiro, Suthinee Attachaipanich, Ruixue Du, Nur Intan Saidaah Mohamed Yusof, Miyu Kinoshita, Momoka Hikosaka, Gen Ohtsuki · 2026 · Frontiers in Cellular Neuroscience
- Targeting microglia microtubules: cytoskeletal remodeling as a druggable hub in neuroinflammation and neurodegenerationCaterina Sanchini, Maria Rosito, Francesca Bartolini, Silvia Di Angelantonio · 2026 · Frontiers in Neuroscience
- Tenascin-C fibronectin D domain is involved in the fine-tuning of glial response to CNS injury in vitroDunja D. Bijelić, Marija Adžić, Mina Perić, Gebhard Reiss, Milena M. Milosevic, Pavle R. Anđjus, Igor Jakovčevski · 2022 · Frontiers in Cell and Developmental Biology
- Sporopollenin exine capsules modulate the function of microglial cellsMengwei Li, Banglian Hu, Zhaojie Wu, Ziwei Wang, Jian Huang Weng, Honghua Zheng, Liping Sun · 2023 · Biomaterials Science
- Contrasting Disease Progression, Microglia Reactivity, Tolerance, and Resistance to Toxoplasma gondii Infection in Two Mouse StrainsDaniel Guerreiro Diniz, Jhonnathan Henrique Palheta de Oliveira, Luma Cristina Ferreira Guerreiro, Gabriel Castro de Menezes, Alexa Camila Lopes de Assis, Tainá Quintella Duarte, Izabelly Biase Damasceno dos Santos, Flávia Domingues Maciel, Gabrielly Lisboa da Silva Soares, Sanderson Corrêa Araújo et al. · 2024 · Biomedicines
- RiboTag-Seq Reveals a Compensatory cAMP Responsive Gene Network in Striatal Microglia Induced by Morphine WithdrawalKevin R. Coffey, Atom J. Lesiak, Russell G. Marx, Emily K. Vo, Gwenn A. Garden, John F. Neumaier · 2020 · bioRxiv (Cold Spring Harbor Laboratory)
- Control of microglial dynamics by the Arp2/3 complex and the autism- and schizophrenia-associated protein CYFIP1Scott-Solache, James, Pei, Jiaxin, Drew, James, López-Doménech, Guillermo, Jolivet, Renaud B., Nieto-Rostro, Manuela, Davenport, Elizabeth C., Arancibia-Cárcamo, I. Lorena, Attwell, David, Kittler, Josef T. · 2026 · Proceedings of the National Academy of Sciences
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- Simultaneous Imaging of Microglial Dynamics and Neuronal Activity in Awake MiceHisato Maruoka, Ryosuke Kamei, Shunsuke Mizutani, Qingrui Liu, Shigeo Okabe · 2022 · Journal of Visualized Experiments
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