Nanoscale Surveillance of the Brain by Microglia via cAMP-Regulated Filopodia

Rho GTPases and the Actin Cytoskeleton

Hall, A. (1998) · Science · doi:10.1126/science.279.5350.509 · Cited by 6,138 · see citing works

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827 · see citing works

A Unique Microglia Type Associated with Restricting Development of Alzheimer’s Disease

Keren-Shaul, H., Spinrad, A., Weiner, A., Matcovitch-Natan, O., Dvir-Szternfeld, R., Ulland, T. K., David, E., Baruch, K., Lara-Astaiso, D., Toth, B., et al. (2017) · Cell · doi:10.1016/j.cell.2017.05.018 · Cited by 5,493 · see citing works

Cell Migration: Integrating Signals from Front to Back

Ridley, A. J., Schwartz, M. A., Burridge, K., Firtel, R., Ginsberg, M. H., Borisy, G. G., Parsons, J. T., & Horwitz, A. R. (2003) · Science · doi:10.1126/science.1092053 · Cited by 4,929 · see citing works

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

Zhang, Y., Chen, K., Sloan, S. A., Bennett, M. L., Scholze, A. R., O'Keeffe, S., Phatnani, H. P., Guarnieri, P., Caneda, C., Ruderisch, N., et al. (2014) · The Journal of Neuroscience · doi:10.1523/jneurosci.1860-14.2014 · Cited by 4,875 · see citing works

Rho, Rac, and Cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

Nobes, C. D., & Hall, A. (1995) · Cell · doi:10.1016/0092-8674(95)90370-4 · Cited by 4,414 · see citing works

Microglia: a sensor for pathological events in the CNS

Kreutzberg, G. W. (1996) · Trends in Neurosciences · doi:10.1016/0166-2236(96)10049-7 · Cited by 4,396 · see citing works

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T. A., Guiducci, E., Dumas, L., et al. (2011) · Science · doi:10.1126/science.1202529 · Cited by 4,244 · see citing works

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Schafer, D. P., Lehrman, E. K., Kautzman, A. G., Koyama, R., Mardinly, A. R., Yamasaki, R., Ransohoff, R. M., Greenberg, M. E., Barres, B. A., & Stevens, B. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.026 · Cited by 4,089 · see citing works

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913 · see citing works

Microglia: Active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676 · see citing works

The Classical Complement Cascade Mediates CNS Synapse Elimination

Stevens, B., Allen, N. J., Vazquez, L. E., Howell, G. R., Christopherson, K. S., Nouri, N., Micheva, K. D., Mehalow, A. K., Huberman, A. D., Stafford, B., et al. (2007) · Cell · doi:10.1016/j.cell.2007.10.036 · Cited by 3,313 · see citing works

Analysis of Fractalkine Receptor CX₃CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632 · see citing works

Schizophrenia risk from complex variation of complement component 4

Sekar, A., Bialas, A. R., de Rivera, H., Davis, A., Hammond, T. R., Kamitaki, N., Tooley, K., Presumey, J., Baum, M., Van Doren, V., et al. (2016) · Nature · doi:10.1038/nature16549 · Cited by 2,394 · see citing works

Complex cell-state changes revealed by single cell RNA sequencing of 76,149 microglia throughout the mouse lifespan and in the injured brain

Hammond, T. R., Dufort, C., Dissing-Olesen, L., Giera, S., Young, A., Wysoker, A., Walker, A. J., Segel, M., Nemesh, J., Saunders, A., et al. (2018) · doi:10.1101/406140 · Cited by 2,225 · see citing works

Immune attack: the role of inflammation in Alzheimer disease

Heppner, F. L., Ransohoff, R. M., & Becher, B. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3880 · Cited by 2,134 · see citing works

A molecular atlas of cell types and zonation in the brain vasculature

Vanlandewijck, M., He, L., Mäe, M. A., Andrae, J., Ando, K., Del Gaudio, F., Nahar, K., Lebouvier, T., Laviña, B., Gouveia, L., et al. (2018) · Nature · doi:10.1038/nature25739 · Cited by 2,074 · see citing works

Cyclic nucleotide phosphodiesterases: functional implications of multiple isoforms

Beavo, J. A. (1995) · Physiological Reviews · doi:10.1152/physrev.1995.75.4.725 · Cited by 1,788 · see citing works

Filopodia: molecular architecture and cellular functions

Mattila, P. K., & Lappalainen, P. (2008) · Nature Reviews Molecular Cell Biology · doi:10.1038/nrm2406 · Cited by 1,699 · see citing works

Microglia in neurodegenerative disease

Perry, V. H., Nicoll, J. A. R., & Holmes, C. (2010) · Nature Reviews Neurology · doi:10.1038/nrneurol.2010.17 · Cited by 1,543 · see citing works

The P2Y12 receptor regulates microglial activation by extracellular nucleotides

Haynes, S. E., Hollopeter, G., Yang, G., Kurpius, D., Dailey, M. E., Gan, W.-B., & Julius, D. (2006) · Nature Neuroscience · doi:10.1038/nn1805 · Cited by 1,542 · see citing works

Microglial interactions with synapses are modulated by visual experience

Tremblay, M.-È., Lowery, R. L., & Majewska, A. K. (2010) · PLoS Biology · doi:10.1371/journal.pbio.1000527 · Cited by 1,542 · see citing works

Actin-Based Cell Motility and Cell Locomotion

Mitchison, T. J., & Cramer, L. P. (1996) · Cell · doi:10.1016/s0092-8674(00)81281-7 · Cited by 1,538 · see citing works

Molecular Mechanisms of Axon Guidance

Dickson, B. J. (2002) · Science · doi:10.1126/science.1072165 · Cited by 1,431 · see citing works

Microglia in physiology and disease

Wolf, S. A., Boddeke, H. W. G. M., & Kettenmann, H. (2017) · Annual Review of Physiology · doi:10.1146/annurev-physiol-022516-034406 · Cited by 1,426 · see citing works

Microglia and brain macrophages in the molecular age: from origin to neuropsychiatric disease

Prinz, M., & Priller, J. (2014) · Nature Reviews Neuroscience · doi:10.1038/nrn3722 · Cited by 1,329 · see citing works

Directed Actin Polymerization Is the Driving Force for Epithelial Cell–Cell Adhesion

Vasioukhin, V., Bauer, C., Yin, M., & Fuchs, E. (2000) · Cell · doi:10.1016/s0092-8674(00)81559-7 · Cited by 1,205 · see citing works

Developmental Heterogeneity of Microglia and Brain Myeloid Cells Revealed by Deep Single-Cell RNA Sequencing

Li, Q., Cheng, Z., Zhou, L., Darmanis, S., Neff, N. F., Okamoto, J., Gulati, G., Bennett, M. L., Sun, L. O., Clarke, L. E., et al. (2019) · Neuron · doi:10.1016/j.neuron.2018.12.006 · Cited by 1,129 · see citing works

The Role of Microglia in the Healthy Brain: Figure 1.

Tremblay, M.-È., Stevens, B., Sierra, A., Wake, H., Bessis, A., & Nimmerjahn, A. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.4158-11.2011 · Cited by 992 · see citing works

Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents

Lugnier, C. (2005) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2005.07.003 · Cited by 873 · see citing works

Localized Effects of cAMP Mediated by Distinct Routes of Protein Kinase A

Taskén, K., & Aandahl, E. M. (2004) · Physiological Reviews · doi:10.1152/physrev.00021.2003 · Cited by 776 · see citing works

S IGNALING AT THE G ROWTH C ONE : Ligand-Receptor Complexes and the Control of Axon Growth and Guidance

Huber, A. B., Kolodkin, A. L., Ginty, D. D., & Cloutier, J. (2003) · Annual Review of Neuroscience · doi:10.1146/annurev.neuro.26.010302.081139 · Cited by 720 · see citing works

Diverse Requirements for Microglial Survival, Specification, and Function Revealed by Defined-Medium Cultures

Bohlen, C. J., Bennett, F. C., Tucker, A. F., Collins, H. Y., Mulinyawe, S. B., & Barres, B. A. (2017) · Neuron · doi:10.1016/j.neuron.2017.04.043 · Cited by 676 · see citing works

Microglia: Dynamic Mediators of Synapse Development and Plasticity

Wu, Y., Dissing-Olesen, L., MacVicar, B. A., & Stevens, B. (2015) · Trends in Immunology · doi:10.1016/j.it.2015.08.008 · Cited by 661 · see citing works

The Growth Cone Cytoskeleton in Axon Outgrowth and GuidancePreprint

Dent, E. W., Gupton, S. L., & Gertler, F. B. (2010) · Cold Spring Harbor Perspectives in Biology · doi:10.1101/cshperspect.a001800 · Cited by 651 · see citing works

AKAPs: from structure to function

Colledge, M., & Scott, J. D. (1999) · Trends in Cell Biology · doi:10.1016/s0962-8924(99)01558-5 · Cited by 611 · see citing works

Microglia contribute to normal myelinogenesis and to oligodendrocyte progenitor maintenance during adulthood

Hagemeyer, N., Hanft, K.-M., Akriditou, M.-A., Unger, N., Park, E. S., Stanley, E. R., Staszewski, O., Dimou, L., & Prinz, M. (2017) · Acta Neuropathologica · doi:10.1007/s00401-017-1747-1 · Cited by 558 · see citing works

The protein kinase A anchoring protein mAKAP coordinates two integrated cAMP effector pathways

Dodge‐Kafka, K. L., Soughayer, J. S., Paré, G. C., Michel, J. J. C., Langeberg, L. K., Kapiloff, M. S., & Scott, J. D. (2005) · Nature · doi:10.1038/nature03966 · Cited by 557 · see citing works

Reciprocal Regulation between Resting Microglial Dynamics and Neuronal Activity In Vivo

Li, Y., Du, X.-F., Liu, C., Wen, Z., & Du, J. (2012) · Developmental Cell · doi:10.1016/j.devcel.2012.10.027 · Cited by 553 · see citing works

A novel microglial subset plays a key role in myelinogenesis in developing brain

Wlodarczyk, A., Holtman, I. R., Krueger, M., Yogev, N., Bruttger, J., Khorooshi, R., Benmamar‐Badel, A., de Boer‐Bergsma, J. J., Martin, N. A., Karram, K., et al. (2017) · The EMBO Journal · doi:10.15252/embj.201696056 · Cited by 535 · see citing works

Immune mediators in the brain and peripheral tissues in autism spectrum disorder

Estes, M. L., & McAllister, A. K. (2015) · Nature Reviews Neuroscience · doi:10.1038/nrn3978 · Cited by 514 · see citing works

Generalized Lévy walks and the role of chemokines in migration of effector CD8+ T cells

Harris, T. H., Banigan, E. J., Christian, D. A., Konradt, C., Wojno, E. D. T., Norose, K., Wilson, E. H., John, B., Weninger, W., Luster, A. D., et al. (2012) · Nature · doi:10.1038/nature11098 · Cited by 512 · see citing works

Neuronal Hyperactivity Recruits Microglial Processes via Neuronal NMDA Receptors and Microglial P2Y12 Receptors after Status Epilepticus

Eyo, U. B., Peng, J., Swiatkowski, P., Mukherjee, A., Bispo, A., & Wu, L.-J. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0416-14.2014 · Cited by 509 · see citing works

Cytokines and schizophrenia: microglia hypothesis of schizophrenia

Monji, A., Kato, T., & Kanba, S. (2009) · Psychiatry and Clinical Neurosciences · doi:10.1111/j.1440-1819.2009.01945.x · Cited by 508 · see citing works

Microglial Ramification, Surveillance, and Interleukin-1β Release Are Regulated by the Two-Pore Domain K+ Channel THIK-1

Madry, C., Kyrargyri, V., Arancibia-Cárcamo, I. L., Jolivet, R., Kohsaka, S., Bryan, R. M., & Attwell, D. (2018) · Neuron · doi:10.1016/j.neuron.2017.12.002 · Cited by 464 · see citing works

Structure, Localization, and Regulation of cGMP-inhibited Phosphodiesterase (PDE3)

Degerman, E., Belfrage, P., & Manganiello, V. C. (1997) · Journal of Biological Chemistry · doi:10.1074/jbc.272.11.6823 · Cited by 432 · see citing works

Regulated Actin Cytoskeleton Assembly at Filopodium Tips Controls Their Extension and Retraction

Mallavarapu, A., & Mitchison, T. J. (1999) · The Journal of Cell Biology · doi:10.1083/jcb.146.5.1097 · Cited by 422 · see citing works

Adenosine A2A receptor mediates microglial process retraction

Orr, A. G., Orr, A. L., Traynelis, S. F., Gross, R. E., & Traynelis, S. F. (2009) · Nature Neuroscience · doi:10.1038/nn.2341 · Cited by 361 · see citing works

Molecular basis of the synergistic inhibition of platelet function by nitrovasodilators and activators of adenylate cyclase: inhibition of cyclic AMP breakdown by cyclic GMP.

Maurice, D. H., & Haslam, R. J. (1990) · Molecular Pharmacology · doi:10.1016/s0026-895x(25)10974-7 · Cited by 351 · see citing works

Rac GTPases control axon growth, guidance and branching

Ng, J., Nardine, T. M., Harms, M. B., Tzu, J., Goldstein, A. Y. N., Sun, Y., Dietzl, G., Dickson, B. J., & Luo, L. (2002) · Nature · doi:10.1038/416442a · Cited by 340 · see citing works

Regulation of actin-based cell migration by cAMP/PKA

Howe, A. K. (2004) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2004.03.005 · Cited by 322 · see citing works

Homeostatic and injury‐induced microglia behavior in the aging brain

Hefendehl, J. K., Neher, J. J., Sühs, R. B., Kohsaka, S., Skodras, A., & Jucker, M. (2014) · Aging Cell · doi:10.1111/acel.12149 · Cited by 319 · see citing works

Activation of Neuronal NMDA Receptors Triggers Transient ATP-Mediated Microglial Process Outgrowth

Dissing-Olesen, L., LeDue, J. M., Rungta, R. L., Hefendehl, J. K., Choi, H. B., & MacVicar, B. A. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.0405-14.2014 · Cited by 286 · see citing works

Lévy Walks Evolve Through Interaction Between Movement and Environmental Complexity

de Jager, M., Weissing, F. J., Herman, P. M. J., Nolet, B. A., & van de Koppel, J. (2011) · Science · doi:10.1126/science.1201187 · Cited by 281 · see citing works

Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases

Baillie, G. S. (2009) · FEBS Journal · doi:10.1111/j.1742-4658.2009.06926.x · Cited by 227 · see citing works

Diversity in Cyclic Nucleotide Phosphodiesterase Isoenzyme Families

Manganiello, V. C., Murata, T., Taira, M., Belfrage, P., & Degerman, E. (1995) · Archives of Biochemistry and Biophysics · doi:10.1006/abbi.1995.1429 · Cited by 224 · see citing works

Effects of norepinephrine on rat cultured microglial cells that express α1, α2, β1 and β2 adrenergic receptors

Mori, K., Ozaki, E., Zhang, B., Yang, L., Yokoyama, A., Takeda, I., Maeda, N., Sakanaka, M., & Tanaka, J. (2002) · Neuropharmacology · doi:10.1016/s0028-3908(02)00211-3 · Cited by 215 · see citing works

Norepinephrine modulates the motility of resting and activated microglia via different adrenergic receptors

Gyoneva, S., & Traynelis, S. F. (2013) · Journal of Biological Chemistry · doi:10.1074/jbc.m113.458901 · Cited by 204 · see citing works

Microglia processes block the spread of damage in the brain and require functional chloride channels

Hines, D. J., Hines, R. M., Mulligan, S. J., & MacVicar, B. A. (2009) · Glia · doi:10.1002/glia.20874 · Cited by 202 · see citing works

P2Y12receptor‐mediated integrin‐β1 activation regulates microglial process extension induced by ATP

Ohsawa, K., Irino, Y., Sanagi, T., Nakamura, Y., Suzuki, E., Inoue, K., & Kohsaka, S. (2010) · Glia · doi:10.1002/glia.20963 · Cited by 157 · see citing works

Filopodia as sensors

Heckman, C. A., & Plummer, H. K. (2013) · Cellular Signalling · doi:10.1016/j.cellsig.2013.07.006 · Cited by 151 · see citing works

ROCK/Cdc42-mediated microglial motility and gliapse formation lead to phagocytosis of degenerating dopaminergic neurons in vivo

Barcia, C., Ros, C. M., Annese, V., Carrillo-de Sauvage, M. A., Ros-Bernal, F., Gómez, A., Yuste, J. E., Campuzano, C. M., de Pablos, V., Fernandez-Villalba, E., et al. (2012) · Scientific Reports · doi:10.1038/srep00809 · Cited by 150 · see citing works

Microglial calcium signal acts as a rapid sensor of single neuron damage in vivo

Eichhoff, G., Brawek, B., & Garaschuk, O. (2010) · Biochimica et Biophysica Acta (BBA) - Molecular Cell Research · doi:10.1016/j.bbamcr.2010.10.018 · Cited by 148 · see citing works

NO mediates microglial response to acute spinal cord injury under ATP control in vivo

Dibaj, P., Nadrigny, F., Steffens, H., Scheller, A., Hirrlinger, J., Schomburg, E. D., Neusch, C., & Kirchhoff, F. (2010) · Glia · doi:10.1002/glia.20993 · Cited by 144 · see citing works

Imaging Activity in Neurons and Glia with a Polr2a-Based and Cre-Dependent GCaMP5G-IRES-tdTomato Reporter Mouse

Gee, J. M., Smith, N., Fernandez, F. R., Economo, M. N., Brunert, D., Rothermel, M., Morris, S. C., Talbot, A., Palumbos, S. D., Ichida, J. M., et al. (2014) · Neuron · doi:10.1016/j.neuron.2014.07.024 · Cited by 139 · see citing works

3DMorph Automatic Analysis of Microglial Morphology in Three Dimensions from Ex Vivo and In Vivo Imaging

York, E. M., LeDue, J. M., Bernier, L., & MacVicar, B. A. (2018) · eNeuro · doi:10.1523/eneuro.0266-18.2018 · Cited by 135 · see citing works

Microglia in Alzheimer’s disease: A multifaceted relationship

ElAli, A., & Rivest, S. (2016) · Brain, Behavior, and Immunity · doi:10.1016/j.bbi.2015.07.021 · Cited by 134 · see citing works

Epac mediates cyclic AMP-dependent axon growth, guidance and regeneration

Murray, A., & Shewan, D. A. (2008) · Molecular and Cellular Neuroscience · doi:10.1016/j.mcn.2008.05.006 · Cited by 127 · see citing works

Small Molecule AKAP-Protein Kinase A (PKA) Interaction Disruptors That Activate PKA Interfere with Compartmentalized cAMP Signaling in Cardiac Myocytes

Frank, C., Szaszák, M., Friedl, S., Drewianka, S., Lorenz, D., Gonçalves, A. C. D. C., Furkert, J., Vargas, C., Schmieder, P., Götz, F. M., et al. (2010) · Journal of Biological Chemistry · doi:10.1074/jbc.m110.160614 · Cited by 107 · see citing works

Involvement of β1 integrin in microglial chemotaxis and proliferation on fibronectin: Different regulations by ADP through PKA

Nasu‐Tada, K., Koizumi, S., & Inoue, K. (2005) · Glia · doi:10.1002/glia.20224 · Cited by 100 · see citing works

Microglial modulation of neuronal activity in the healthy brain

York, E. M., Bernier, L., & MacVicar, B. A. (2018) · Developmental Neurobiology · doi:10.1002/dneu.22571 · Cited by 98 · see citing works

Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease

Gyoneva, S., Shapiro, L. P., Lazo, C. R., Garnier‐Amblard, E. C., Smith, Y., Miller, G. W., & Traynelis, S. F. (2014) · Neurobiology of Disease · doi:10.1016/j.nbd.2014.03.004 · Cited by 97 · see citing works

Intracellular calcium dynamics in cortical microglia responding to focal laser injury in the PC::G5-tdT reporter mouse

Pozner, A., Xu, B., Palumbos, S. D., Gee, J. M., Tvrdík, P., & Capecchi, M. R. (2015) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2015.00012 · Cited by 94 · see citing works

Spatial regulation of the cAMP-dependent protein kinase during chemotactic cell migration

Howe, A. K., Baldor, L. C., & Hogan, B. P. (2005) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0507072102 · Cited by 89 · see citing works

Spreading Depression Sends Microglia on Lévy Flights

Grinberg, Y. Y., MILTON, J. G., & Kraig, R. P. (2011) · PLoS ONE · doi:10.1371/journal.pone.0019294 · Cited by 85 · see citing works

ATP and NO dually control migration of microglia to nerve lesions

Duan, Y., Sahley, C. L., & Muller, K. J. (2008) · Developmental Neurobiology · doi:10.1002/dneu.20689 · Cited by 67 · see citing works

Effects of the ecto-ATPase apyrase on microglial ramification and surveillance reflect cell depolarization, not ATP depletion

Madry, C., Arancibia‐Cárcamo, I. L., Kyrargyri, V., Chan, V. T. T., Hamilton, N. B., & Attwell, D. (2018) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1715354115 · Cited by 58 · see citing works

Early activation, motility, and homing of neonatal microglia to injured neurons does not require protein synthesis

Kurpius, D., Wilson, N., Fuller, L. C., Hoffman, A., & Dailey, M. E. (2006) · Glia · doi:10.1002/glia.20355 · Cited by 46 · see citing works

Phosphoinositide 3-kinase γ mediates microglial phagocytosis via lipid kinase-independent control of cAMP

Schmidt, C., Schneble, N., Müller, J., Bauer, R., Perino, A., Marone, R., Rybalkin, S. D., Wymann, M. P., Hirsch, E., & Wetzker, R. (2012) · Neuroscience · doi:10.1016/j.neuroscience.2012.12.036 · Cited by 41 · see citing works

Repeatable target localization for long-term in vivo imaging of mice with 2-photon microscopy

Hefendehl, J. K., Milford, D., Eicke, D., Wegenast‐Braun, B. M., Calhoun, M. E., Grathwohl, S. A., Jucker, M., & Liebig, C. (2011) · Journal of Neuroscience Methods · doi:10.1016/j.jneumeth.2011.10.029 · Cited by 30 · see citing works

Nitric oxide/cyclic GMP signaling regulates motility of a microglial cell line and primary microglia in vitro

Scheiblich, H., Roloff, F., Singh, V., Stangel, M., Stern, M. K., & Bicker, G. (2014) · Brain Research · doi:10.1016/j.brainres.2014.03.048 · Cited by 25 · see citing works

Fixation and Immunolabeling of Brain Slices: SNAPSHOT Method

Dissing‐Olesen, L., & MacVicar, B. A. (2015) · Current Protocols in Neuroscience · doi:10.1002/0471142301.ns0123s71 · Cited by 20 · see citing works

Three-Dimensional Nanostructure of an Intact Microglia Cell

Bolasco, G., Weinhard, L., Boissonnet, T., Neujahr, R., & Gross, C. T. (2018) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2018.00105 · Cited by 17 · see citing works

Negative feedback control of neuronal activity by microglia

Badimon, A., Strasburger, H. J., Ayata, P., Chen, X., Nair, A., Ikegami, A., Hwang, P., Chan, A. T., Graves, S. M., Uweru, J. O., et al. (2020) · Nature · doi:10.1038/s41586-020-2777-8 · Cited by 979 · see citing works

The Semantics of Microglia Activation: Neuroinflammation, Homeostasis, and Stress

Woodburn, S. C., Bollinger, J. L., & Wohleb, E. S. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02309-6 · Cited by 783 · see citing works

Microglia use TAM receptors to detect and engulf amyloid β plaques

Huang, Y., Happonen, K. E., Burrola, P. G., O’Connor, C., Hah, N., Huang, L., Nimmerjahn, A., & Lemke, G. (2021) · Nature Immunology · doi:10.1038/s41590-021-00913-5 · Cited by 483 · see citing works

Astrocytes and microglia: In sickness and in health

Vainchtein, I. D., & Molofsky, A. V. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.01.003 · Cited by 450 · see citing works

Microglia morphophysiological diversity and its implications for the CNS

Vidal-Itriago, A., Radford, R. A. W., Aramideh, J. A., Maurel, C., Scherer, N. M., Don, E. K., Lee, A., Chung, R. S., Graeber, M. B., & Morsch, M. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.997786 · Cited by 412 · see citing works

Neuronal network activity controls microglial process surveillance in awake mice via norepinephrine signaling

Liu, Y., Ying, Y., Li, Y., Eyo, U. B., Chen, T., Zheng, J., Umpierre, A. D., Zhu, J., Bosco, D. B., Dong, H., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0511-3 · Cited by 389 · see citing works

Noradrenergic signaling in the wakeful state inhibits microglial surveillance and synaptic plasticity in the mouse visual cortex

Stowell, R. D., Sipe, G. O., Dawes, R. P., Batchelor, H. N., Lordy, K. A., Whitelaw, B. S., Stoessel, M. B., Bidlack, J. M., Brown, E., Sur, M., et al. (2019) · Nature Neuroscience · doi:10.1038/s41593-019-0514-0 · Cited by 321 · see citing works

Lipid accumulation induced by APOE4 impairs microglial surveillance of neuronal-network activity

Victor, M. B., Leary, N., Luna, X., Meharena, H. S., Scannail, A. N., Bozzelli, P. L., Samaan, G., Murdock, M. H., von Maydell, D., Effenberger, A. H., et al. (2022) · Cell Stem Cell · doi:10.1016/j.stem.2022.07.005 · Cited by 316 · see citing works

Behaviorally consequential astrocytic regulation of neural circuits

Nagai, J., Yu, X., Papouin, T., Cheong, E., Freeman, M. R., Monk, K. R., Hastings, M. H., Haydon, P. G., Rowitch, D. H., Shaham, S., et al. (2020) · Neuron · doi:10.1016/j.neuron.2020.12.008 · Cited by 311 · see citing works

Microglial metabolic flexibility supports immune surveillance of the brain parenchyma

Bernier, L., York, E. M., Kamyabi, A., Choi, H. B., Weilinger, N. L., & MacVicar, B. A. (2020) · Nature Communications · doi:10.1038/s41467-020-15267-z · Cited by 302 · see citing works

Shaping Neuronal Fate: Functional Heterogeneity of Direct Microglia-Neuron Interactions

Cserép, C., Pósfai, B., & Dénes, Á. (2021) · Neuron · doi:10.1016/j.neuron.2020.11.007 · Cited by 256 · see citing works

How microglia sense and regulate neuronal activity

Umpierre, A. D., & Wu, L. (2021) · Glia · doi:10.1002/glia.23961 · Cited by 237 · see citing works

A new genetic strategy for targeting microglia in development and disease

McKinsey, G. L., Lizama, C. O., Keown-Lang, A. E., Niu, A., Santander, N., Larpthaveesarp, A., Chee, E., Gonzalez, F. F., & Arnold, T. D. (2020) · eLife · doi:10.7554/elife.54590 · Cited by 176 · see citing works

Human Microglia Show Unique Transcriptional Changes in Alzheimer's Disease

Prater, K. E., Green, K. J., Mamde, S., Sun, W., Cochoit, A., Smith, C. L., Chiou, K. L., Heath, L., Rose, S. E., Wiley, J., et al. (2023) · Nature Aging · doi:10.1038/s43587-023-00424-y · Cited by 164 · see citing works

Microglial Gi-dependent dynamics regulate brain network hyperexcitability

Merlini, M., Rafalski, V. A., Ma, K., Keun-young Kim, A., Bushong, E. A., Coronado, P. E. R., Yan, Z., Mendiola, A. S., Sözmen, E. G., Ryu, J. K., et al. (2020) · Nature Neuroscience · doi:10.1038/s41593-020-00756-7 · Cited by 146 · see citing works

Microglia at the blood brain barrier in health and disease

Mayer, M. G., & Fischer, T. (2024) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2024.1360195 · Cited by 128 · see citing works

Microglia-neuron interaction at nodes of Ranvier depends on neuronal activity through potassium release and contributes to remyelination

Ronzano, R., Roux, T., Thétiot, M., Aigrot, M., Richard, L., Lejeune, F., Mazuir, E., Vallat, J., Lubetzki, C., & Desmazières, A. (2021) · Nature Communications · doi:10.1038/s41467-021-25486-7 · Cited by 115 · see citing works

Tuning neural circuits and behaviors by microglia in the adult brain

Zhao, S., Umpierre, A. D., & Wu, L. (2024) · Trends in Neurosciences · doi:10.1016/j.tins.2023.12.003 · Cited by 116 · see citing works

Microglia regulate sleep through calcium-dependent modulation of norepinephrine transmission

Ma, C., Li, B., Silverman, D., Ding, X., Li, A., Xiao, C., Huang, G., Worden, K., Muroy, S. E., Chen, W., et al. (2024) · Nature Neuroscience · doi:10.1038/s41593-023-01548-5 · Cited by 122 · see citing works

Biomaterial-supported MSC transplantation enhances cell–cell communication for spinal cord injury

Lv, B., Zhang, X., Yuan, J., Chen, Y., Ding, H., Cao, X., & Huang, A. (2021) · Stem Cell Research & Therapy · doi:10.1186/s13287-020-02090-y · Cited by 114 · see citing works

The contribution of glial cells to Huntington's disease pathogenesis

Wilton, D. K., & Stevens, B. (2020) · Neurobiology of Disease · doi:10.1016/j.nbd.2020.104963 · Cited by 112 · see citing works

Plasticity of microglia

Augusto‐Oliveira, M., Arrifano, G. D. P., Delage, C. I., Tremblay, M., Lopez, M. E. C., & Verkhratsky, A. (2021) · Biological reviews/Biological reviews of the Cambridge Philosophical Society · doi:10.1111/brv.12797 · Cited by 107 · see citing works

Microglial Metabolic Reprogramming: Emerging Insights and Therapeutic Strategies in Neurodegenerative Diseases

Miao, J., Chen, L., Pan, X., Li, L.-Q., Zhao, B., & Lan, J. X. (2023) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-023-01376-y · Cited by 110 · see citing works

The Role of Microglia in Neuroinflammation of the Spinal Cord after Peripheral Nerve Injury

Pottorf, T. S., Rotterman, T. M., McCallum, W. M., Haley-Johnson, Z., & Álvarez, F. J. (2022) · Cells · doi:10.3390/cells11132083 · Cited by 93 · see citing works

Noteworthy perspectives on microglia in neuropsychiatric disorders

Zhu, H., Guan, A., Liu, J., Li, P., Zhang, Z., & Wang, S. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02901-y · Cited by 90 · see citing works

An injury-responsive Rac-to-Rho GTPase switch drives activation of muscle stem cells through rapid cytoskeletal remodeling

Kann, A. P., Hung, M., Wang, W., Nguyen, J., Gilbert, P. M., Wu, Z., & Krauss, R. S. (2022) · Cell stem cell · doi:10.1016/j.stem.2022.04.016 · Cited by 78 · see citing works

Central Nervous System Remyelination: Roles of Glia and Innate Immune Cells

Baaklini, C. S., Rawji, K. S., Duncan, G. J., Ho, M. F. S., & Plemel, J. R. (2019) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2019.00225 · Cited by 80 · see citing works

Necrotic reshaping of the glioma microenvironment drives disease progression

Markwell, S. M., Ross, J., Olson, C. L., & Brat, D. J. (2022) · Acta Neuropathologica · doi:10.1007/s00401-021-02401-4 · Cited by 77 · see citing works

Microglia dynamics in sleep/wake states and in response to sleep loss

Deurveilher, S., Golovin, T., Hall, S., & Semba, K. (2020) · Neurochemistry International · doi:10.1016/j.neuint.2020.104944 · Cited by 72 · see citing works

More than meets the eye: The role of microglia in healthy and diseased retina

Murenu, E., Gerhardt, M.-J., Biel, M., & Michalakis, S. (2022) · Frontiers in Immunology · doi:10.3389/fimmu.2022.1006897 · Cited by 73 · see citing works

P2Y13 receptors regulate microglial morphology, surveillance, and resting levels of interleukin 1β release

Kyrargyri, V., Madry, C., Rifat, A., Arancibia‐Cárcamo, I. L., Jones, S. P., Chan, V. T. T., Xu, Y., Robaye, B., & Attwell, D. (2019) · Glia · doi:10.1002/glia.23719 · Cited by 69 · see citing works

Loss of microglial MCT4 leads to defective synaptic pruning and anxiety-like behavior in mice

Monsorno, K., Ginggen, K., Ivanov, A., Buckinx, A., Lalive, A. L., Tchenio, A., Benson, S., Vendrell, M., D’Alessandro, A., Beule, D., et al. (2023) · Nature Communications · doi:10.1038/s41467-023-41502-4 · Cited by 71 · see citing works

Actin-mediated Microglial Chemotaxis via G-Protein Coupled Purinergic Receptor in Alzheimer’s Disease

Das, R. R., & Chinnathambi, S. (2020) · Neuroscience · doi:10.1016/j.neuroscience.2020.09.024 · Cited by 71 · see citing works

Physiology of Astroglial Excitability

Verkhratsky, A., Semyanov, A. V., & Zorec, R. (2020) · Function · doi:10.1093/function/zqaa016 · Cited by 66 · see citing works

Microglial transcriptome analysis in the rNLS8 mouse model of TDP-43 proteinopathy reveals discrete expression profiles associated with neurodegenerative progression and recovery

Hunter, M., Spiller, K. J., Dominique, M. A., Xu, H. W., Hunter, F. W., Fang, T., Canter, R. G., Roberts, C. J., Ransohoff, R. M., Trojanowski, J. Q., et al. (2021) · Acta Neuropathologica Communications · doi:10.1186/s40478-021-01239-x · Cited by 66 · see citing works

Microglial remodeling of actin network by Tau oligomers, via G protein‐coupled purinergic receptor, P2Y12R ‐driven chemotaxis

Das, R. R., & Chinnathambi, S. (2021) · Traffic · doi:10.1111/tra.12784 · Cited by 62 · see citing works

Control of Neuroinflammation through Radiation-Induced Microglial Changes

Boyd, A., Byrne, S., Middleton, R. J., Banati, R. B., & Liu, G. J. (2021) · Cells · doi:10.3390/cells10092381 · Cited by 62 · see citing works

Polarized microtubule remodeling transforms the morphology of reactive microglia and drives cytokine release

Adrian, M., Weber, M., Tsai, M., Glock, C., Kahn, O. I., Phu, L., Cheung, T. K., Meilandt, W. J., Rose, C. M., & Hoogenraad, C. C. (2023) · Nature Communications · doi:10.1038/s41467-023-41891-6 · Cited by 58 · see citing works

Current perspectives on microglia-neuron communication in the central nervous system: Direct and indirect modes of interaction

Hu, Y., & Tao, W. (2024) · Journal of Advanced Research · doi:10.1016/j.jare.2024.01.006 · Cited by 61 · see citing works

Deletion of <i>Abi3</i> gene locus exacerbates neuropathological features of Alzheimer’s disease in a mouse model of Aβ amyloidosis

Karahan, H., Smith, D. C., Kim, B., Dabin, L. C., Al-Amin, M. M., Wijeratne, H. R. S., Pennington, T., Viana di Prisco, G., McCord, B., Lin, P. B.-C., et al. (2021) · Science Advances · doi:10.1126/sciadv.abe3954 · Cited by 53 · see citing works

Microglia Activation and Inflammation During the Death of Mammalian Photoreceptors

Karlen, S. J., Miller, E. B., & Burns, M. E. (2020) · Annual Review of Vision Science · doi:10.1146/annurev-vision-121219-081730 · Cited by 57 · see citing works

TRPV4 channels mediate the mechanoresponse in retinal microglia

Redmon, S. N., Yarishkin, O. V., Lakk, M., Jo, A. O., Mustafić, E., Tvrdík, P., & Križaj, D. (2021) · Glia · doi:10.1002/glia.23979 · Cited by 54 · see citing works

Gamma frequency activation of inhibitory neurons in the acute phase after stroke attenuates vascular and behavioral dysfunction

Balbi, M., Xiao, D., Vega, M. J., Hu, H., Vanni, M. P., Bernier, L., LeDue, J. M., MacVicar, B. A., & Murphy, T. H. (2021) · Cell Reports · doi:10.1016/j.celrep.2021.108696 · Cited by 53 · see citing works

Super-resolution STED microscopy in live brain tissue

Calovi, S., Soria, F. N., & Tønnesen, J. (2021) · Neurobiology of Disease · doi:10.1016/j.nbd.2021.105420 · Cited by 52 · see citing works

Microglia Provide Structural Resolution to Injured Dendrites after Severe Seizures

Eyo, U. B., Haruwaka, K., Mo, M., Campos-Salazar, A. B., Wang, L., Speros, X. S., Sabu, S., Xu, P., & Wu, L. (2020) · Cell Reports · doi:10.1016/j.celrep.2021.109080 · Cited by 53 · see citing works

Microtubule organization and dynamics in oligodendrocytes, astrocytes, and microglia

Weigel, M. K., Wang, L., & Fu, M. (2020) · Developmental Neurobiology · doi:10.1002/dneu.22753 · Cited by 52 · see citing works

Instant FLIM enables 4D in vivo lifetime imaging of intact and injured zebrafish and mouse brains

Zhang, Y., Guldner, I. H., Nichols, E. L., Benirschke, D., Smith, C. J., Zhang, S., & Howard, S. S. (2021) · Optica · doi:10.1364/optica.426870 · Cited by 51 · see citing works

The Safeguarding Microglia: Central Role for P2Y12 Receptors

Lin, S.-S., Tang, Y., Illés, P., & Verkhratsky, A. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2020.627760 · Cited by 46 · see citing works

The role of P2Y12 in the kinetics of microglial self-renewal and maturation in the adult visual cortex in vivo

Mendes, M. S., Le, L., Atlas, J., Brehm, Z., Ladron-de-Guevara, A., Matei, E., Lamantia, C., McCall, M. N., & Majewska, A. K. (2021) · eLife · doi:10.7554/elife.61173 · Cited by 46 · see citing works

DynaMorph: self-supervised learning of morphodynamic states of live cells

Wu, Z., Chhun, B. B., Popova, G., Guo, S.-M., Kim, C. N., Yeh, L.-H., Nowakowski, T. J., Zou, J., & Mehta, S. B. (2022) · Molecular Biology of the Cell · doi:10.1091/mbc.e21-11-0561 · Cited by 42 · see citing works

Microglia Reactivity Entails Microtubule Remodeling From Acentrosomal to Centrosomal Arrays

Rosito, M., Sanchini, C., Gosti, G., Moreno, M., Panfilis, S. D., Giubettini, M., Debellis, D., Catalano, F., Peruzzi, G., Marotta, R., et al. (2022) · Cell Reports · doi:10.1016/j.celrep.2023.112104 · Cited by 43 · see citing works

Neuron–Glial Interactions in Health and Brain Cancer

Pan, Y., & Monje, M. (2022) · Advanced Biology · doi:10.1002/adbi.202200122 · Cited by 45 · see citing works

Microglia control small vessel calcification via TREM2

Zarb, Y., Sridhar, S., Nassiri, S., Utz, S. G., Schaffenrath, J., Maheshwari, U., Rushing, E. J., Nilsson, K. P. R., Delorenzi, M., Colonna, M., et al. (2021) · Science Advances · doi:10.1126/sciadv.abc4898 · Cited by 44 · see citing works

Homeostatic state of microglia in a rat model of chronic sleep restriction

Hall, S., Deurveilher, S., Robertson, G. S., & Semba, K. (2020) · SLEEP · doi:10.1093/sleep/zsaa108 · Cited by 40 · see citing works

Microglia Degrade Extracellular Tau Oligomers Deposits via Purinergic P2Y12-Driven Podosomes, Filopodia Formation and Induce Chemotaxis

Chinnathambi, S., & Das, R. R. (2021) · Cell & Bioscience · doi:10.1186/s13578-023-01028-0 · Cited by 45 · see citing works

The role of P2Y12 receptor inhibition in ischemic stroke on microglia, platelets and vascular smooth muscle cells

Li, F., Xu, D., Hou, K., Gou, X., & Li, Y. (2020) · Journal of Thrombosis and Thrombolysis · doi:10.1007/s11239-020-02098-4 · Cited by 40 · see citing works

Psychological Stress as a Risk Factor for Accelerated Cellular Aging and Cognitive Decline: The Involvement of Microglia-Neuron Crosstalk

Carrier, M., Šimončičová, E., St‐Pierre, M., McKee, C., & Tremblay, M. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.749737 · Cited by 37 · see citing works

Microglial heterogeneity in chronic pain

Sideris-Lampretsas, G., & Malcangio, M. (2021) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2021.06.005 · Cited by 37 · see citing works

Dynamics of Microglia Activation in the Ischemic Brain: Implications for Myelin Repair and Functional Recovery

Raffaele, S., & Fumagalli, M. (2022) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2022.950819 · Cited by 38 · see citing works

Modulating Neuroinflammation as a Prospective Therapeutic Target in Alzheimer’s Disease

Lee, E., & Chang, Y. (2025) · Cells · doi:10.3390/cells14030168 · Cited by 38 · see citing works

A role for the centrosome in regulating the rate of neuronal efferocytosis by microglia in vivo

Möller, K., Brambach, M., Villani, A., Gallo, E., Gilmour, D. T., & Peri, F. (2022) · eLife · doi:10.7554/elife.82094 · Cited by 34 · see citing works

Low-intensity pulsed ultrasound stimulation (LIPUS) modulates microglial activation following intracortical microelectrode implantation

Li, F., Gallego, J., Tirko, N. N., Greaser, J., Bashe, D., Patel, R., Shaker, E., Valkenburg, G. E. V., Alsubhi, A. S., Wellman, S. M., et al. (2024) · Nature Communications · doi:10.1038/s41467-024-49709-9 · Cited by 35 · see citing works

Mitigation of Carbon Nanotube Neurosensor Induced Transcriptomic and Morphological Changes in Mouse Microglia with Surface Passivation

Yang, D., Yang, S. J., Bonis-O’Donnell, J. T. D., Pinals, R. L., & Landry, M. P. (2020) · ACS Nano · doi:10.1021/acsnano.0c06154 · Cited by 35 · see citing works

Movers and shakers: Microglial dynamics and modulation of neural networks

Whitelaw, B. S., Stoessel, M. B., & Majewska, A. K. (2022) · Glia · doi:10.1002/glia.24323 · Cited by 33 · see citing works

Calcium Signaling in Neurons and Glial Cells: Role of Cav1 channels

Alves, V. S., Alves-Silva, H. S., Orts, D. J. B., Ribeiro-Silva, L., Arcisio-Miranda, M., & Oliveira, F. A. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.09.041 · Cited by 34 · see citing works

Microglial tissue surveillance: The never‐resting gardener in the developing and adult CNS

Petry, P., Oschwald, A., & Kierdorf, K. (2023) · European Journal of Immunology · doi:10.1002/eji.202250232 · Cited by 34 · see citing works

PDE inhibition in distinct cell types to reclaim the balance of synaptic plasticity

Rombaut, B., Kessels, S., Schepers, M., Tiane, A., Paes, D., Solomina, Y., Piccart, E., van den Hove, D., Brône, B., Prickaerts, J., et al. (2020) · Theranostics · doi:10.7150/thno.50701 · Cited by 32 · see citing works

Inhibition of microglial β-glucocerebrosidase hampers the microglia-mediated antioxidant and protective response in neurons

Brunialti, E., Villa, A. M., Mekhaeil, M., Mornata, F., Vegeto, E., Maggi, A. C., Monte, D. A. D., & Ciana, P. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02272-2 · Cited by 30 · see citing works

Modulation of Microglial Function by ATP-Gated P2X7 Receptors: Studies in Rat, Mice and Human

Tewari, M., Michalski, S. A., & Egan, T. M. (2024) · Cells · doi:10.3390/cells13020161 · Cited by 33 · see citing works

PACAP and VIP Modulate LPS-Induced Microglial Activation and Trigger Distinct Phenotypic Changes in Murine BV2 Microglial Cells

Karunia, J., Niaz, A., Mandwie, M., Broome, S. T., Keay, K. A., Waschek, J. A., Al‐Badri, G., & Castorina, A. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms222010947 · Cited by 28 · see citing works

Role of Glial Cells in Neuronal Function, Mood Disorders, and Drug Addiction

Tizabi, Y., Getachew, B., Hauser, S. R., Tsytsarev, V., Manhães, A. C., & da Silva, V. D. A. (2024) · Brain Sciences · doi:10.3390/brainsci14060558 · Cited by 27 · see citing works

Chimeric GPCRs mimic distinct signaling pathways and modulate microglia responses

Schulz, R., Korkut-Demirbaş, M., Venturino, A., Colombo, G., & Siegert, S. (2022) · Nature Communications · doi:10.1038/s41467-022-32390-1 · Cited by 27 · see citing works

A cytoskeleton symphony: Actin and microtubules in microglia dynamics and aging

Socodato, R., & Relvas, J. B. (2024) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2024.102586 · Cited by 28 · see citing works

Microglia modulate the structure and function of the hippocampus after early-life seizures

Andoh, M., Ikegaya, Y., & Koyama, R. (2020) · Journal of Pharmacological Sciences · doi:10.1016/j.jphs.2020.09.003 · Cited by 27 · see citing works

Microglial Morphology Across Distantly Related Species: Phylogenetic, Environmental and Age Influences on Microglia Reactivity and Surveillance States

Paulo, D. C., Bento‐Torres, J., Filho, C. S., de Oliveira, T. C. G., de Sousa, A. A., dos Reis, R. R., dos Santos, Z. A., de Lima, C. M., Augusto‐Oliveira, M., Said, N. M., et al. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.683026 · Cited by 26 · see citing works

Microglia in CNS infections: insights from Toxoplasma gondii and other pathogens

Cowan, M. N., Sethi, I., & Harris, T. H. (2022) · Trends in Parasitology · doi:10.1016/j.pt.2021.12.004 · Cited by 26 · see citing works

Spinal cord microglia in health and disease

Kolos, E. A., & Korzhevsky, D. (2020) · Acta Naturae · doi:10.32607/actanaturae.10934 · Cited by 23 · see citing works

A cAMP-Related Gene Network in Microglia Is Inversely Regulated by Morphine Tolerance and Withdrawal

Coffey, K. R., Lesiak, A. J., Marx, R. E., Vo, E. K., Garden, G. A., & Neumaier, J. F. (2021) · Biological Psychiatry Global Open Science · doi:10.1016/j.bpsgos.2021.07.011 · Cited by 25 · see citing works

Effects of norepinephrine on microglial neuroinflammation and neuropathic pain

Zou, H., Li, J., Zhou, J., Yi, X., & Cao, S. (2021) · Ibrain · doi:10.1002/ibra.12001 · Cited by 25 · see citing works

In vivo imaging of the phagocytic dynamics underlying efficient clearance of adult‐born hippocampal granule cells by ramified microglia

Kamei, R., & Okabe, S. (2023) · Glia · doi:10.1002/glia.24379 · Cited by 26 · see citing works

Sex and interferon gamma signaling regulate microglia migration in the adult mouse cortex in vivo

Boghozian, R., Sharma, S., Narayana, K., Cheema, M. S., & Brown, C. E. (2023) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2302892120 · Cited by 24 · see citing works

In vivo imaging in mouse spinal cord reveals that microglia prevent degeneration of injured axons

Wu, W., He, Y., Chen, Y., Fu, Y., He, S., Liu, K., & Qu, J. Y. (2024) · Nature Communications · doi:10.1038/s41467-024-53218-0 · Cited by 24 · see citing works

Dimethyl Fumarate Reduces Microglia Functional Response to Tissue Damage and Favors Brain Iron Homeostasis

Pagani, F., Testi, C., Grimaldi, A., Corsi, G., Cortese, B., Basilico, B., Baiocco, P., Panfilis, S. D., Ragozzino, D., & Angelantonio, S. D. (2019) · Neuroscience · doi:10.1016/j.neuroscience.2019.10.041 · Cited by 24 · see citing works

Assessing Microglial Dynamics by Live Imaging

Andoh, M., & Koyama, R. (2021) · Frontiers in Immunology · doi:10.3389/fimmu.2021.617564 · Cited by 23 · see citing works

Gut Microbiota as a Hidden Player in the Pathogenesis of Alzheimer’s Disease

Choi, H., Lee, D., & Mook‐Jung, I. (2022) · Journal of Alzheimer s Disease · doi:10.3233/jad-215235 · Cited by 23 · see citing works

Acute inhibition of transient receptor potential vanilloid‐type 4 cation channel halts cytoskeletal dynamism in microglia

Beeken, J., Mertens, M., Stas, N., Kessels, S., Aerts, L., Janssen, B., Mussen, F., Pinto, S., Vennekens, R., Rigo, J., et al. (2022) · Glia · doi:10.1002/glia.24243 · Cited by 24 · see citing works

Microglial Rac1 is essential for experience-dependent brain plasticity and cognitive performance

Socodato, R., Almeida, T. O., Portugal, C. C., Santos, E. C. D. S., Tedim-Moreira, J., Galvão-Ferreira, J., Canedo, T., Baptista, F. I., Magalhães, A., Ambrósio, A. F., et al. (2023) · Cell Reports · doi:10.1016/j.celrep.2023.113447 · Cited by 23 · see citing works

Axonal CB1 Receptors Mediate Inhibitory Bouton Formation via cAMP Increase and PKA

Liang, J., Kruijssen, D. L. H., Verschuuren, A. C. J., Voesenek, B. J. B., Benavides, F. F. W., González, M. S., Ruiter, M., & Wierenga, C. J. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0851-21.2021 · Cited by 20 · see citing works

Phosphoinositide-3-Kinase γ Is Not a Predominant Regulator of ATP-Dependent Directed Microglial Process Motility or Experience-Dependent Ocular Dominance Plasticity

Whitelaw, B. S., Matei, E. K., & Majewska, A. K. (2020) · eNeuro · doi:10.1523/eneuro.0311-20.2020 · Cited by 20 · see citing works

Pathways linking Alzheimer’s disease risk genes expressed highly in microglia

Hodges, A. K., Piers, T. M., Collier, D., Cousins, O., & Pocock, J. M. (2021) · Neuroimmunology and Neuroinflammation · doi:10.20517/2347-8659.2020.60 · Cited by 21 · see citing works

Muscle stem cells get a new look: Dynamic cellular projections as sensors of the stem cell niche

Krauss, R. S., & Kann, A. P. (2023) · BioEssays · doi:10.1002/bies.202200249 · Cited by 20 · see citing works

Microglia undergo molecular and functional adaptations to dark and light phases in male laboratory mice

Mattei, D., Ivanov, A., Hammer, J., Ugursu, B., Schalbetter, S. M., Richetto, J., Weber‐Stadlbauer, U., Mueller, F. S., Scarborough, J., Wolf, S. A., et al. (2024) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2024.07.007 · Cited by 20 · see citing works

Optical Control of G-Actin with a Photoswitchable Latrunculin

Vepřek, N. A., Cooper, M. H., Laprell, L., Yang, E. J.-N., Folkerts, S., Bao, R., Boczkowska, M., Palmer, N. J., Domínguez, R., Oertner, T. G., et al. (2024) · Journal of the American Chemical Society · doi:10.1021/jacs.3c10776 · Cited by 19 · see citing works

Primary cilia-mediated regulation of microglial secretion in Alzheimer’s disease

Yeo, S., Jang, J., Jung, H. J., Lee, H., & Choe, Y. (2023) · Frontiers in Molecular Biosciences · doi:10.3389/fmolb.2023.1250335 · Cited by 18 · see citing works

Nonneuronal contributions to synaptic function

Hodebourg, R., Scofield, M. D., Kalivas, P. W., & Kuhn, B. N. (2025) · Neuron · doi:10.1016/j.neuron.2025.04.004 · Cited by 17 · see citing works

The metabolic engine of cognition: microglia–neuron interactions in health, ageing and disease

Asimakidou, E., Pluchino, S., Silva, B. A., & Peruzzotti‐Jametti, L. (2025) · Nature Metabolism · doi:10.1038/s42255-025-01409-4 · Cited by 21 · see citing works

Simultaneous imaging of redox states in dystrophic neurites and microglia at Aβ plaques indicate lysosome accumulation not microglia correlate with increased oxidative stress

Wendt, S., Johnson, S., Weilinger, N. L., Groten, C. J., Sorrentino, S., Frew, J., Yang, L. L. H., Choi, H. B., Nygaard, H. B., & MacVicar, B. A. (2022) · Redox Biology · doi:10.1016/j.redox.2022.102448 · Cited by 16 · see citing works

Phenomic Microglia Diversity as a Druggable Target in the Hippocampus in Neurodegenerative Diseases

Lana, D., Magni, G., Landucci, E., Wenk, G. L., Pellegrini-Giampietro, D. E., & Giovannini, M. G. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms241813668 · Cited by 19 · see citing works

Sex chromosomes and sex hormones differently shape microglial properties during normal physiological conditions in the adult mouse hippocampus

Bobotis, B. C., Khakpour, M., Braniff, O., de Andrade, E. G., Gargus, M., Allen, M., Carrier, M., Baillargeon, J., Rangachari, M., & Tremblay, M.-È. (2025) · Journal of Neuroinflammation · doi:10.1186/s12974-025-03341-6 · Cited by 17 · see citing works

A focus on the normal-appearing white and gray matter within the multiple sclerosis brain: a link to smoldering progression

González, G. M., Hart, B. A. ‘., Bugiani, M., Plemel, J. R., Schenk, G. J., Kooij, G., & Luchicchi, A. (2025) · Acta Neuropathologica · doi:10.1007/s00401-025-02923-1 · Cited by 19 · see citing works

The relation between the head circumference and long-term outcome in intrauterine growth restriction infants

Wang, Q., Sun, H., Xiong, H., & Kang, W. (2008) · Early Human Development · doi:10.1016/j.earlhumdev.2008.09.109

Regulation of Cyclic AMP Synthesis in Microglial Cells and Possible Role of Cyclic AMP in Neuroprotection

Levi, G. (2000) · Research and perspectives in neurosciences · doi:10.1007/978-3-642-59643-8_11 · Cited by 3 · see citing works

The roles of microglia in response to pathological stimuli in the brain

Hines, D. J. (2009) · cIRcle (University of British Columbia) · doi:10.14288/1.0067256 · Cited by 1 · see citing works

Intracellular Ca2⁺ dynamics are required for microglial process motility during surveillance and in response to injury

Tiwari, S., Zeng, F., Zhou, Y., Chok, A., Brazhe, A., Semyanov, A. V., Zhu, K., Xiang, X., & Kettenmann, H. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-04013-9

Compound C induces the ramification of murine microglia in an AMPK-independent and small rhogtpase-dependent manner

Huang, C., Lu, X., Wang, J. L., Tong, L., Ling, Y., Jiang, B., Yang, R., & Zhang, W. (2016) · Neuroscience · doi:10.1016/j.neuroscience.2016.06.018 · Cited by 11 · see citing works