Lack of Follow-up of Pediatric Patients With Celiac Disease
Open accessAbstract
Celiac disease (CD) is often diagnosed in childhood, and the treatment is a lifelong gluten-free diet (GFD).1,2 It may take several years to gain competence in the skills required to follow a GFD successfully. Inadequately treated CD is associated with bone fractures, nutritional deficiencies, and lymphoma.3,4 Healthcare providers are key resources for patients with CD. Consultation with a dietitian with GFD expertise at diagnosis and annual disease-specific follow-up care are recommended.2,5 The primary objective of this study was to evaluate adherence to guidelines for dietitian consultation and follow-up for children with CD. A secondary objective was to identify factors associated with loss to follow-up.
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Full normalization of both TGA levels and histopathology may take over two years, particularly in those with severe small bowel lesions and high TGA levels at diagnosis.
“Full normalization of both TGA levels and histopathology may take over two years, particularly in those with severe small bowel lesions and high TGA levels at diagnosis (25-27).”
From ESPGHAN Position Paper on Management and Follow-up of Children and Adolescents With Celiac Disease. (2022) · cites this paper as [27]
The Results report a median TTG IgA normalization time of 17 months, with an interquartile range extending to 32 months, supporting that antibody normalization can take more than two years. The paper does not report time to histopathological normalization or show that severe small-bowel lesions or high antibody levels at diagnosis prolong normalization. (LLM, conf=0.87)
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- Authors
- Blansky, B. A., Hintze, Z. J., Alhassan, E., Leichtner, A. M., Weir, D. C., & Silvester, J. A.
- Affiliations
- Boston University (US)
- Boston Children's Hospital (US)
- West Virginia University (US)
- Corresponding author
- Silvester, Jocelyn A.
- Venue
- Clinical Gastroenterology and Hepatology
- Publisher
- Elsevier BV
- Published
- 2019-11
- Volume
- 17
- Issue
- 12
- Pages
- 2603-2604
- ISSN
- 1542-3565 (ISSN-L)
- PMC
- PMC6599537
- OpenAlex
- W2907463056
- Cited by
- 28
- References
- 7
- Citations by year
- 2026: 3 · 2025: 4 · 2024: 3 · 2023: 6 · 2022: 4 · 2021: 4 · 2020: 1 · 2019: 3
- FWCI
- 1.84
- Type
- journal article
- Language
- en
- Open access
- green
- www.ncbi.nlm.nih.gov
- Locations
- Clinical Gastroenterology and Hepatology (publishedVersion)
- PubMed (publishedVersion)
- PubMed Central (acceptedVersion)
- Funders
- NIH (T32 DK 07760)
- Topics
- Health Sciences › Medicine › Gastroenterology › Celiac Disease Research and Management
- Health Sciences › Medicine › Psychiatry and Mental health › Child Nutrition and Feeding Issues
- Health Sciences › Health Professions › Health Information Management › Dietetics, Nutrition, and Education
- Keywords
- celiac disease, pediatric patients, loss to follow-up, gluten-free diet, dietitian consultation, clinical practice guideline adherence, nutritional deficiency
- MeSH terms
- Adolescent, Age Factors, Celiac Disease, Child, Continuity of Patient Care, Female, Humans, Male, Medicaid, Referral and Consultation, Retrospective Studies, United States, Cohort Studies, Siblings, Lost to Follow-Up, Nutritionists
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