Ginkgolic Acid Inhibits Protein SUMOylation by Blocking Formation of the E1-SUMO Intermediate

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Exploring the Role that SUMOylation Plays in Regulating CDK2 Function in Cancer Cells

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Regulation of BMP-induced osteoblastic differentiation by Ubc9 knockdown-mediated inhibition of SUMO modification

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Transcriptional silencing of endogenous retroviruses by the novel lysine methyltransferase co-repressor hnRNP K

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Étude de la SUMOylation dans l’immunité innée et l’oncogenèse

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Ion Channel SUMOylation: a Novel Role for SUMO in Homeostatic Regulation of Multiple Ionic Conductances

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Efficient, Scalable Syntheses of Ginkgolic Acids

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Dietary and Metabolic Compounds Affecting Covalent Histone Modifications

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Characterization and Association of CFHR5 Gene Polymorphism with Fatty Acid Composition and Cholesterol in Sheep

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Chmp1A regulates pancreatic cancer cell growth via SIM-medicated SUMOylation and UIM-mediated ubiquitination, opposed through NLS-mediated signaling activitiesPreprint

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Understanding the role UFMylation plays in prostate cancer

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Ginkgolic acid regulates myogenic development by influencing the proliferation and differentiation of C2C12 myoblast cells

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Structure Activity Relationship Studies of Anacardic Acid Derivatives Targeting Sumo E1Preprint

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Synthetic inhibition of the SUMO pathway by targeting the SAE1 component via TAK-981 compound impairs tumor growth and chemosensitizers embryonal and alveolar rhabdomyosarcoma cell linesPreprint

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Ginkgolic acids (C15 and C17) induce autophagy and apoptosis in gastric carcinoma HGC cells by inducing ER stress

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Streptooctatin A induces autophagy and promotes α-synuclein clearance by directly binding to SUMO2 and inhibiting SUMOylation

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Blockage of SUMO E1 enzyme inhibits ocular lens fibrosis by mediating SMAD4 SUMOylation

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SUMO E1 covalent allosteric inhibitors upregulate polyamine synthesis via the MAT2A-AdoMetDC axis

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SUMOylation and NEDDylation in kidney diseases

Chen, Z., Li, D., Zhang, J., Wei, B.-Y., Zhao, H., Li, P., & Chen, D. (2025) · Experimental and Molecular Pathology · doi:10.1016/j.yexmp.2025.105010

Targeting the deSUMOylase Ulp2 in Candida glabrata for antifungal therapies: in silico identification of silymarin and honokiol as potential inhibitors

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Additional file 1 of ESM1 enhances fatty acid synthesis and vascular mimicry in ovarian cancer by utilizing the PKM2-dependent warburg effect within the hypoxic tumor microenvironment

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Additional file 3 of Identification of cell-biologic mechanisms of coronary artery spasm and its ex vivo diagnosis using peripheral blood-derived iPSCs

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Ginkgolic acid attenuates echinococcus granulosus infection-induced hepatic fibrosis by inhibiting Smad4 SUMOylation

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SUMOylation and anticancer drug resistance

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Congener-resolved hazard identification of ginkgolic acids as emerging natural contaminants

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Identification of new regulators for PML nuclear bodies

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ROS/SUMO relationship in the chemotherapeutic treatment of Acute Myeloid Leukemia

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BindingDB Entry 50043329: Identification of quinazolinyloxy biaryl urea as a new class of SUMO activating enzyme 1 inhibitors.

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BindingDB Entry 50014392: Discovery of TAK-981, a First-in-Class Inhibitor of SUMO-Activating Enzyme for the Treatment of Cancer.

BindingDB (2022) · UC San Diego · doi:10.7270/q2pk0kz8

BindingDB Entry 50042513: Exploring a new frontier in cancer treatment: targeting the ubiquitin and ubiquitin-like activating enzymes.

BindingDB (2013) · UC San Diego · doi:10.7270/q29p32zt

BindingDB Entry 50047019: Identification of new SUMO activating enzyme 1 inhibitors using virtual screening and scaffold hopping.

BindingDB (2017) · UC San Diego · doi:10.7270/q2cj8gbv

BindingDB Entry 50045683: Synthetic derivatives of the SUMO consensus sequence provide a basis for improved substrate recognition.

BindingDB (2016) · UC San Diego · doi:10.7270/q2j104vs

BindingDB Entry 50016052: Small-molecule inhibitors targeting small ubiquitin-like modifier pathway for the treatment of cancers and other diseases.

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Inhibition of protein SUMOylation by davidiin, an ellagitannin from Davidia involucrata

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Targeting SUMOylation with Anacardic Acid Derivatives: Novel Insights into EGF Pathway Dysregulation in Cancer Using an In Silico Approach

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Controlling protein SUMOylation

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