Pseudomonas aeruginosa Disrupts Caenorhabditis elegans Iron Homeostasis, Causing a Hypoxic Response and Death

MICROBIAL BIOFILMS

Costerton, J. W., Lewandowski, Z., Caldwell, D. E., Korber, D. R., & Lappin-Scott, H. M. (1995) · Annual Review of Microbiology · doi:10.1146/annurev.mi.49.100195.003431 · Cited by 4,718 · see citing works

C. elegans EGL-9 and mammalian homologs define a family of dioxygenases that regulate HIF by prolyl hydroxylation

Epstein, A. C. R., Gleadle, J. M., McNeill, L. A., Hewitson, K. S., O'Rourke, J., Mole, D. R., Mukherji, M., Metzen, E., Wilson, M. I., Dhanda, A., et al. (2001) · Cell · doi:10.1016/s0092-8674(01)00507-4 · Cited by 3,333 · see citing works

Maintenance of C. elegans

Stiernagle, T. (2006) · WormBook · doi:10.1895/wormbook.1.101.1 · Cited by 2,788 · see citing works

Microbial pathogenesis in cystic fibrosis: mucoid Pseudomonas aeruginosa and Burkholderia cepacia

Govan, J. R. W., & Deretic, V. P. (1996) · Microbiological Reviews · doi:10.1128/mr.60.3.539-574.1996 · Cited by 1,671 · see citing works

Common Virulence Factors for Bacterial Pathogenicity in Plants and Animals

Rahme, L. G., Stevens, E. J., Wolfort, S. F., Shao, J., Tompkins, R. G., & Ausubel, F. M. (1995) · Science · doi:10.1126/science.7604262 · Cited by 1,344 · see citing works

Establishment of infection: lessons from a versatile opportunist

Lyczak, J. B., Cannon, C. L., & Pier, G. B. (2000) · Microbes and Infection · doi:10.1016/s1286-4579(00)01259-4 · Cited by 1,343 · see citing works

Killing of Caenorhabditis elegans by Pseudomonas aeruginosa used to model mammalian bacterial pathogenesis

Tan, M., Mahajan‐Miklos, S., & Ausubel, F. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.2.715 · Cited by 1,008 · see citing works

Improved structure, function and compatibility for CellProfiler: modular high-throughput image analysis software

Kamentsky, L. D., Jones, T. R., Fraser, A. N., Bray, M., Logan, D. J., Madden, K. L., Ljosa, V., Rueden, C., Eliceiri, K. W., & Carpenter, A. E. (2011) · Bioinformatics · doi:10.1093/bioinformatics/btr095 · Cited by 1,002 · see citing works

An ordered, nonredundant library of Pseudomonas aeruginosa strain PA14 transposon insertion mutants

Liberati, N. T., Urbach, J. M., Miyata, S., Lee, D. G., Drenkard, E., Wu, G., Villanueva, J. M., Wei, T., & Ausubel, F. M. (2006) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0511100103 · Cited by 971 · see citing works

Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity

Fisher, J. F., Meroueh, S. O., & Mobashery, S. (2005) · Chemical Reviews · doi:10.1021/cr030102i · Cited by 914 · see citing works

Molecular Mechanisms of Bacterial Virulence Elucidated Using a Pseudomonas aeruginosa– Caenorhabditis elegans Pathogenesis Model

Mahajan‐Miklos, S., Tan, M., Rahme, L. G., & Ausubel, F. M. (1999) · Cell · doi:10.1016/s0092-8674(00)80958-7 · Cited by 821 · see citing works

Quorum sensing and environmental adaptation in Pseudomonas aeruginosa: a tale of regulatory networks and multifunctional signal molecules

Williams, P. M., & Cámara, M. (2009) · Current Opinion in Microbiology · doi:10.1016/j.mib.2009.01.005 · Cited by 797 · see citing works

The phenazine pyocyanin is a terminal signalling factor in the quorum sensing network of Pseudomonas aeruginosa

Dietrich, L. E. P., Price‐Whelan, A., Petersen, A., Whiteley, M., & Newman, D. K. (2006) · Molecular Microbiology · doi:10.1111/j.1365-2958.2006.05306.x · Cited by 718 · see citing works

Interdependence of hypoxic and innate immune responses

Nizet, V., & Johnson, R. S. (2009) · Nature Reviews Immunology · doi:10.1038/nri2607 · Cited by 708 · see citing works

P. aeruginosa quorum-sensing systems and virulence

Smith, R. S. (2003) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(03)00008-0 · Cited by 705 · see citing works

Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)

Peyssonnaux, C., Zinkernagel, A. S., Schuepbach, R. A., Rankin, E., Vaulont, S., Haase, V. H., Nizet, V., & Johnson, R. S. (2007) · Journal of Clinical Investigation · doi:10.1172/jci31370 · Cited by 639 · see citing works

Pseudomonas aeruginosa killing of Caenorhabditis elegans used to identify P. aeruginosa virulence factors

Tan, M., Rahme, L. G., Sternberg, J. A., Tompkins, R. G., & Ausubel, F. M. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.5.2408 · Cited by 618 · see citing works

Long-Lived C. elegans daf-2 Mutants Are Resistant to Bacterial Pathogens

Garsin, D. A., Villanueva, J. M., Begun, J., Kim, D. H., Sifri, C. D., Calderwood, S. B., Ruvkun, G., & Ausubel, F. M. (2003) · Science · doi:10.1126/science.1080147 · Cited by 610 · see citing works

Siderophore-mediated signaling regulates virulence factor production in <i>Pseudomonas</i> <i>aeruginosa</i>

Lamont, I. L., Beare, P. A., Ochsner, U., Vasil, A. I., & Vasil, M. L. (2002) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.092016999 · Cited by 584 · see citing works

Pyoverdin is essential for virulence of Pseudomonas aeruginosa

Meyer, J., Neely, A. N., Stintzi, A. P., Georges, C., & Holder, I. A. (1996) · Infection and Immunity · doi:10.1128/iai.64.2.518-523.1996 · Cited by 523 · see citing works

International Nosocomial Infection Control Consortium (INICC) report, data summary for 2003-2008, issued June 2009

Rosenthal, V., Maki, D. G., Jamulitrat, S., Medeiros, E. A., Todi, S. K., Yepes, D., Leblebicioğlu, H., Khader, I. A., Miranda-Novales, M. G., Berba, R. P., et al. (2010) · American Journal of Infection Control · doi:10.1016/j.ajic.2009.12.004 · Cited by 515 · see citing works

Genetics and molecular biology of siderophore-mediated iron transport in bacteria

Crosa, J. H. (1989) · Microbiological Reviews · doi:10.1128/mr.53.4.517-530.1989 · Cited by 403 · see citing works

Contribution of specific Pseudomonas aeruginosa virulence factors to pathogenesis of pneumonia in a neonatal mouse model of infection

Tang, H. B., DiMango, E., Bryan, R. A., Gambello, M. J., Iglewski, B. H., Goldberg, J. B., & Prince, A. S. (1996) · Infection and Immunity · doi:10.1128/iai.64.1.37-43.1996 · Cited by 401 · see citing works

Understanding the control of Pseudomonas aeruginosa alginate synthesis and the prospects for management of chronic infections in cystic fibrosis

Ramsey, D. M., & Wozniak, D. J. (2005) · Molecular Microbiology · doi:10.1111/j.1365-2958.2005.04552.x · Cited by 392 · see citing works

The response of Pseudomonas aeruginosa to iron: genetics, biochemistry and virulence

Vasil, M. L., & Ochsner, U. A. (1999) · Molecular Microbiology · doi:10.1046/j.1365-2958.1999.01586.x · Cited by 367 · see citing works

Nosocomial Infections Due to Multidrug‐Resistant Pseudomonas aeruginosa: Epidemiology and Treatment Options

Obritsch, M. D., Fish, D. N., MacLaren, R., & Jung, R. (2005) · Pharmacotherapy The Journal of Human Pharmacology and Drug Therapy · doi:10.1592/phco.2005.25.10.1353 · Cited by 342 · see citing works

Lethal paralysis of Caenorhabditis elegans by Pseudomonas aeruginosa

Darby, C., Cosma, C. L., Thomas, J. H., & Manoil, C. (1999) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.96.26.15202 · Cited by 314 · see citing works

The Caenorhabditis elegans hif-1 gene encodes a bHLH-PAS protein that is required for adaptation to hypoxia

Jiang, H., Guo, R. J., & Powell‐Coffman, J. A. (2001) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.141234698 · Cited by 303 · see citing works

Use of model plant hosts to identify Pseudomonas aeruginosa virulence factors

Rahme, L. G., Tan, M., Le, L. S., Wong, S. M. S., Tompkins, R. G., Calderwood, S. B., & Ausubel, F. M. (1997) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.94.24.13245 · Cited by 300 · see citing works

Multidrug Efflux Pumps: Expression Patterns and Contribution to Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

de Kievit, T. R., Parkins, M. D., Gillis, R. J., Srikumar, R., Ceri, H., Poole, K., Iglewski, B. H., & Storey, D. G. (2001) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.45.6.1761-1770.2001 · Cited by 296 · see citing works

Siderophore activity of pyoverdin for Pseudomonas aeruginosa

Cox, C. D., & Adams, P. (1985) · Infection and Immunity · doi:10.1128/iai.48.1.130-138.1985 · Cited by 272 · see citing works

Impact of Siderophore Production on Pseudomonas aeruginosa Infections in Immunosuppressed Mice

Takase, H., Nitanai, H., Hoshino, K., & Otani, T. (2000) · Infection and Immunity · doi:10.1128/iai.68.4.1834-1839.2000 · Cited by 270 · see citing works

Roles of the HIF-1 Hypoxia-inducible Factor during Hypoxia Response in Caenorhabditis elegans

Shen, C., Nettleton, D. S., Jiang, M., Kim, S. K., & Powell‐Coffman, J. A. (2005) · Journal of Biological Chemistry · doi:10.1074/jbc.m501894200 · Cited by 233 · see citing works

Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1

Zaborin, A., Romanowski, K. S. S., Gerdes, S., Holbrook, C., Lepine, F. L., Long, J., Poroyko, V. A., Diggle, S. P., Wilke, A., Righetti, K., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813199106 · Cited by 220 · see citing works

Iron uptake regulation in Pseudomonas aeruginosa

Cornélis, P., Matthijs, S., & Oeffelen, L. V. (2009) · BioMetals · doi:10.1007/s10534-008-9193-0 · Cited by 218 · see citing works

Host Translational Inhibition by Pseudomonas aeruginosa Exotoxin A Triggers an Immune Response in Caenorhabditis elegans

McEwan, D. L., Kirienko, N. V., & Ausubel, F. M. (2012) · Cell Host & Microbe · doi:10.1016/j.chom.2012.02.007 · Cited by 211 · see citing works

High-Throughput Screen for Novel Antimicrobials using a Whole Animal Infection Model

Moy, T. I., Conery, A. L., Larkins‐Ford, J., Wu, G., Mazitschek, R., Casadei, G., Lewis, K., Carpenter, A. E., & Ausubel, F. M. (2009) · ACS Chemical Biology · doi:10.1021/cb900084v · Cited by 208 · see citing works

Characterization of an Endoprotease (PrpL) Encoded by a PvdS-Regulated Gene inPseudomonas aeruginosa

Wilderman, P. J., Vasil, A. I., Johnson, Z., Wilson, M. J., Cunliffe, H. E., Lamont, I. L., & Vasil, M. L. (2001) · Infection and Immunity · doi:10.1128/iai.69.9.5385-5394.2001 · Cited by 205 · see citing works

Role of the ferric uptake regulator of Pseudomonas aeruginosa in the regulation of siderophores and exotoxin A expression: purification and activity on iron-regulated promoters

Ochsner, U. A., Vasil, A. I., & Vasil, M. L. (1995) · Journal of Bacteriology · doi:10.1128/jb.177.24.7194-7201.1995 · Cited by 198 · see citing works

Models of Caenorhabditis elegans Infection by Bacterial and Fungal Pathogens

Powell, J. R., & Ausubel, F. M. (2008) · Humana Press eBooks · doi:10.1007/978-1-59745-570-1_24 · Cited by 192 · see citing works

Genome-Wide Identification of Pseudomonas aeruginosa Virulence-Related Genes Using a Caenorhabditis elegans Infection Model

Feinbaum, R. L., Urbach, J. M., Liberati, N. T., Djonović, S., Adonizio, A. L., Carvunis, A., & Ausubel, F. M. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002813 · Cited by 188 · see citing works

Identification of Pseudomonas aeruginosa Phenazines that Kill Caenorhabditis elegans

Cezairliyan, B. O., Vinayavekhin, N., Lee, D. G., Yuen, G. J., Saghatelian, A., & Ausubel, F. M. (2013) · PLoS Pathogens · doi:10.1371/journal.ppat.1003101 · Cited by 177 · see citing works

Caenorhabditis elegans: a model genetic host to study Pseudomonas aeruginosa pathogenesis

Tan, M. (2000) · Current Opinion in Microbiology · doi:10.1016/s1369-5274(99)00047-8 · Cited by 170 · see citing works

Effects of siderophores on the growth of Pseudomonas aeruginosa in human serum and transferrin

Ankenbauer, R. G., Sriyosachati, S., & Cox, C. D. (1985) · Infection and Immunity · doi:10.1128/iai.49.1.132-140.1985 · Cited by 164 · see citing works

Transferrin and lactoferrin undergo proteolytic cleavage in the Pseudomonas aeruginosa-infected lungs of patients with cystic fibrosis

Britigan, B. E., Hayek, M. B., Doebbeling, B. N., & Fick, R. B. (1993) · Infection and Immunity · doi:10.1128/iai.61.12.5049-5055.1993 · Cited by 156 · see citing works

The effect of human serum transferrin and milk lactoferrin on hydroxyl radical formation from superoxide and hydrogen peroxide.

Baldwin, D. A., Jenny, E. R., & Aisen, P. (1984) · Journal of Biological Chemistry · doi:10.1016/s0021-9258(18)90707-6 · Cited by 145 · see citing works

Evolutionary perspectives on innate immunity from the study of Caenorhabditis elegans

Kim, D. H., & Ausubel, F. M. (2004) · Current Opinion in Immunology · doi:10.1016/j.coi.2004.11.007 · Cited by 145 · see citing works

The DAF‐2 insulin‐like signaling pathway independently regulates aging and immunity in C. elegans

Evans, E., Chen, W. C., & Tan, M. (2008) · Aging Cell · doi:10.1111/j.1474-9726.2008.00435.x · Cited by 143 · see citing works

Dihydroaeruginoic acid synthetase and pyochelin synthetase, products of the pchEF, are induced by extracellular pyochelin in Pseudornonas aeruginosa

Reimmann, C., Serino, L., Beyeler, M., & Haa�, D. (1998) · Microbiology · doi:10.1099/00221287-144-11-3135 · Cited by 127 · see citing works

Diffuse panbronchiolitis and cystic fibrosis: East meets West.

Høiby, N. (1994) · Thorax · doi:10.1136/thx.49.6.531 · Cited by 121 · see citing works

Metal trafficking via siderophores in Gram-negative bacteria: Specificities and characteristics of the pyoverdine pathway

Schalk, I. J. (2008) · Journal of Inorganic Biochemistry · doi:10.1016/j.jinorgbio.2007.11.017 · Cited by 119 · see citing works

Role of PvdQ in Pseudomonas aeruginosa virulence under iron-limiting conditions

Nadal‐Jimenez, P., Koch, G., Papaioannou, E., Wahjudi, M., Krzeslak, J., Coenye, T., Cool, R. H., & Quax, W. J. (2009) · Microbiology · doi:10.1099/mic.0.030973-0 · Cited by 109 · see citing works

The roles of mucD and alginate in the virulence of Pseudomonas aeruginosa in plants, nematodes and mice

Yorgey, P., Rahme, L. G., Tan, M., & Ausubel, F. M. (2001) · Molecular Microbiology · doi:10.1046/j.1365-2958.2001.02580.x · Cited by 106 · see citing works

Caenorhabditis elegans Semi-Automated Liquid Screen Reveals a Specialized Role for the Chemotaxis Gene cheB2 in Pseudomonas aeruginosa Virulence

Garvis, S., Munder, A., Ball, G., de Bentzmann, S., Wiehlmann, L., Ewbank, J. J., Tümmler, B., & Filloux, A. (2009) · PLoS Pathogens · doi:10.1371/journal.ppat.1000540 · Cited by 98 · see citing works

Analysis of the Pseudomonas aeruginosa Regulon Controlled by the Sensor Kinase KinB and Sigma Factor RpoN

Damron, F. H., Owings, J. P., Okkotsu, Y., Varga, J. J., Schurr, J. R., Goldberg, J. B., Schurr, M. J., & Yu, H. D. (2011) · Journal of Bacteriology · doi:10.1128/jb.06105-11 · Cited by 87 · see citing works

Pseudomonal Infections in Patients with COPD

Lieberman, D. B., & Lieberman, D. (2003) · American Journal of Respiratory Medicine · doi:10.1007/bf03256673 · Cited by 80 · see citing works

HIF-1 Regulates Iron Homeostasis in Caenorhabditis elegans by Activation and Inhibition of Genes Involved in Iron Uptake and Storage

Romney, S. J., Newman, B. S., Thacker, C. M., & Leibold, E. A. (2011) · PLoS Genetics · doi:10.1371/journal.pgen.1002394 · Cited by 74 · see citing works

Possible role of bacterial siderophores in inflammation. Iron bound to the Pseudomonas siderophore pyochelin can function as a hydroxyl radical catalyst.

Coffman, T. J., Cox, C. D., Edeker, B. L., & Britigan, B. E. (1990) · Journal of Clinical Investigation · doi:10.1172/jci114805 · Cited by 72 · see citing works

PERSISTENT HIF-1?? ACTIVATION IN GUT ISCHEMIA/REPERFUSION INJURY: POTENTIAL ROLE OF BACTERIA AND LIPOPOLYSACCHARIDE

Koury, J., Deitch, E. A., Homma, H., Abungu, B., Gangurde, P., Condon, M. R., Lu, Q., Xu, D.-Z., & Feinman, R. (2004) · Shock · doi:10.1097/01.shk.0000135256.67441.3f · Cited by 61 · see citing works

C. elegans SWAN-1 Binds to EGL-9 and Regulates HIF-1-Mediated Resistance to the Bacterial Pathogen Pseudomonas aeruginosa PAO1

Shao, Z., Zhang, Y., Qi, Y., Saldanha, J. N., & Powell‐Coffman, J. A. (2010) · PLoS Pathogens · doi:10.1371/journal.ppat.1001075 · Cited by 51 · see citing works

Pseudomonas aeruginosa Alkyl Quinolones Repress Hypoxia-Inducible Factor 1 (HIF-1) Signaling through HIF-1α Degradation

Legendre, C., Reen, F. J., Mooij, M. J., McGlacken, G. P., Adams, C., & O’Gara, F. (2012) · Infection and Immunity · doi:10.1128/iai.00554-12 · Cited by 49 · see citing works

Has nature already identified all useful antibacterial targets?

Bumann, D. (2008) · Current Opinion in Microbiology · doi:10.1016/j.mib.2008.08.002 · Cited by 46 · see citing works

The Sensor Kinase KinB Regulates Virulence in Acute Pseudomonas aeruginosa Infection

Chand, N. S., Lee, J. S.-W., Clatworthy, A. E., Golas, A. J., Smith, R. S., & Hung, D. T. (2011) · Journal of Bacteriology · doi:10.1128/jb.01546-10 · Cited by 46 · see citing works

Genome-Wide Analysis Reveals Novel Genes Essential for Heme Homeostasis in Caenorhabditis elegans

Severance, S., Rajagopal, A., Rao, A. U., Cerqueira, G., Mitreva, M., El-Sayed, N. M., Krause, M., & Hamza, I. (2010) · PLoS Genetics · doi:10.1371/journal.pgen.1001044 · Cited by 41 · see citing works

The Two-Component Sensor KinB Acts as a Phosphatase To Regulate Pseudomonas aeruginosa Virulence

Chand, N. S., Clatworthy, A. E., & Hung, D. T. (2012) · Journal of Bacteriology · doi:10.1128/jb.01168-12 · Cited by 33 · see citing works

Impaired expression of hypoxia-inducible factor-1α in cystic fibrosis airway epithelial cells – A role for HIF-1 in the pathophysiology of CF?

Legendre, C., Mooij, M. J., Adams, C., & O’Gara, F. (2011) · Journal of Cystic Fibrosis · doi:10.1016/j.jcf.2011.02.005 · Cited by 32 · see citing works

EGL-9 Controls C. elegans Host Defense Specificity through Prolyl Hydroxylation-Dependent and -Independent HIF-1 Pathways

Luhachack, L. G., Visvikis, O., Wollenberg, A. C., Lacy‐Hulbert, A., Stuart, L. M., & Irazoqui, J. E. (2012) · PLoS Pathogens · doi:10.1371/journal.ppat.1002798 · Cited by 31 · see citing works

Iron in infection and immunity

Cassat, J. E., & Skaar, E. P. (2013) · Cell Host &amp; Microbe · doi:10.1016/j.chom.2013.04.010 · Cited by 1,214 · see citing works

Siderophores in Iron Metabolism: From Mechanism to Therapy Potential

Wilson, B., Bogdan, A. R., Miyazawa, M., Hashimoto, K., & Tsuji, Y. (2016) · Trends in Molecular Medicine · doi:10.1016/j.molmed.2016.10.005 · Cited by 479 · see citing works

The Natural Biotic Environment of Caenorhabditis elegans

Hinrich Schulenburg, Y., & Félix, M. (2017) · Genetics · doi:10.1534/genetics.116.195511 · Cited by 439 · see citing works

Caenorhabditis elegans responses to bacteria from its natural habitats

Samuel, B. S., Rowedder, H., Braendle, C., Félix, M., & Ruvkun, G. (2016) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1607183113 · Cited by 411 · see citing works

Mitochondrial UPR-regulated innate immunity provides resistance to pathogen infection

Pellegrino, M. W., Nargund, A. M., Kirienko, N. V., Gillis, R., Fiorese, C. J., & Haynes, C. M. (2014) · Nature · doi:10.1038/nature13818 · Cited by 369 · see citing works

Molecular Mechanisms of Nematode-Nematophagous Microbe Interactions: Basis for Biological Control of Plant-Parasitic Nematodes

Li, J., Zou, C., Xu, J., Ji, X., Niu, X., Yang, J., Huang, X., & Zhang, K. (2015) · Annual Review of Phytopathology · doi:10.1146/annurev-phyto-080614-120336 · Cited by 299 · see citing works

Diverging roles of bacterial siderophores during infection

Holden, V. I., & Bachman, M. A. (2015) · Metallomics · doi:10.1039/c4mt00333k · Cited by 274 · see citing works

Control and dysregulation of redox signalling in the gastrointestinal tract

Campbell, E. L., & Colgan, S. P. (2018) · Nature Reviews Gastroenterology & Hepatology · doi:10.1038/s41575-018-0079-5 · Cited by 258 · see citing works

Iron-starvation-induced mitophagy mediates lifespan extension upon mitochondrial stress in C.elegans

Schiavi, A., Maglioni, S., Palikaras, K., Shaik, A., Strappazzon, F., Brinkmann, V., Torgovnick, A., Castelein, N., De Henau, S., Braeckman, B. P., et al. (2015) · Current Biology · doi:10.1016/j.cub.2015.05.059 · Cited by 209 · see citing works

Siderophores: Importance in bacterial pathogenesis and applications in medicine and industry

Khasheii, B., Mahmoodi, P., & Mohammadzadeh, A. (2021) · Microbiological Research · doi:10.1016/j.micres.2021.126790 · Cited by 210 · see citing works

Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1α Stabilization during Pneumonia

Holden, V. I., Breen, P., Houle, S., Dozois, C. M., & Bachman, M. A. (2016) · mBio · doi:10.1128/mbio.01397-16 · Cited by 204 · see citing works

Survival assays using Caenorhabditis elegans

Park, H. H., Jung, Y., & Lee, S. (2017) · Molecules and Cells · doi:10.14348/molcells.2017.0017 · Cited by 204 · see citing works

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa

Kirienko, N. V., Ausubel, F. M., & Ruvkun, G. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424954112 · Cited by 197 · see citing works

Microbial Siderophore Enterobactin Promotes Mitochondrial Iron Uptake and Development of the Host via Interaction with ATP Synthase

Qi, B., & Han, M. (2018) · Cell · doi:10.1016/j.cell.2018.07.032 · Cited by 164 · see citing works

Autophagy and innate immunity: Insights from invertebrate model organisms

Kuo, C., Hansen, M., & Troemel, E. R. (2017) · Autophagy · doi:10.1080/15548627.2017.1389824 · Cited by 160 · see citing works

Pyoverdine, a siderophore from Pseudomonas aeruginosa , translocates into C. elegans , removes iron, and activates a distinct host response

Kang, D., Kirienko, D. R., Webster, P. J., Fisher, A. L., & Kirienko, N. V. (2018) · Virulence · doi:10.1080/21505594.2018.1449508 · Cited by 159 · see citing works

Repurposing Salicylanilide Anthelmintic Drugs to Combat Drug Resistant Staphylococcus aureus

Rajamuthiah, R., Fuchs, B. B., Conery, A. L., Kim, W., Jayamani, E., Kwon, B., Ausubel, F. M., & Mylonakis, E. E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0124595 · Cited by 148 · see citing works

Interdependence between iron acquisition and biofilm formation in Pseudomonas aeruginosa

Kang, D., & Kirienko, N. V. (2018) · The Journal of Microbiology · doi:10.1007/s12275-018-8114-3 · Cited by 136 · see citing works

Interspecies competition triggers virulence and mutability in <i>Candida albicans</i> – <i>Pseudomonas aeruginosa</i> mixed biofilms

Trejo-Hernández, A., Andrade-Domínguez, A., Hernández, M., & Encarnación, S. (2014) · The ISME Journal · doi:10.1038/ismej.2014.53 · Cited by 135 · see citing works

Iron sequestration by transferrin 1 mediates nutritional immunity in <i>Drosophila melanogaster</i>

Iatsenko, I., Marra, A., Boquete, J.-P., Peña, J., & Lemaitre, B. (2020) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1914830117 · Cited by 133 · see citing works

Pseudomonas aeruginosa PA14 Pathogenesis in Caenorhabditis elegans

Kirienko, N. V., Cezairliyan, B. O., Ausubel, F. M., & Powell, J. R. (2014) · Methods in molecular biology · doi:10.1007/978-1-4939-0473-0_50 · Cited by 128 · see citing works

Metabolism and the UPR mt

Lin, Y., & Haynes, C. M. (2016) · Molecular Cell · doi:10.1016/j.molcel.2016.02.004 · Cited by 123 · see citing works

Caenorhabditis elegans: a model to understand host–microbe interactions

Kumar, A., Baruah, A., Tomioka, M., Iino, Y., Kalita, M. C., & Khan, M. R. (2019) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-019-03319-7 · Cited by 118 · see citing works

The Use of Plant Growth-Promoting Bacteria to Prevent Nematode Damage to Plants

Gamalero, E., & Glick, B. R. (2020) · Biology · doi:10.3390/biology9110381 · Cited by 117 · see citing works

Effect of Human Burn Wound Exudate on Pseudomonas aeruginosa Virulence

Gonzalez, M. R., Fleuchot, B., Lauciello, L., Jafari, P., Applegate, L. A., Raffoul, W., Que, Y.-A., & Perron, K. (2016) · mSphere · doi:10.1128/msphere.00111-15 · Cited by 109 · see citing works

Pyoverdine-Dependent Virulence of Pseudomonas aeruginosa Isolates From Cystic Fibrosis Patients

Kang, D., Revtovich, A. V., Chen, Q., Shah, K. N., Cannon, C. L., & Kirienko, N. V. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02048 · Cited by 104 · see citing works

Drug discovery: Insights from the invertebrate Caenorhabditis elegans

Giunti, S., Andersen, N., Rayes, D., & Rosa, M. J. D. (2021) · Pharmacology Research & Perspectives · doi:10.1002/prp2.721 · Cited by 102 · see citing works

Innate immunity in C. elegans

Martineau, C. N., Kirienko, N. V., & Pujol, N. (2021) · Current topics in developmental biology/Current Topics in Developmental Biology · doi:10.1016/bs.ctdb.2020.12.007 · Cited by 101 · see citing works

Microbial pathogenesis and host defense in the nematode C. elegans

Cohen, L. B., & Troemel, E. R. (2014) · Current Opinion in Microbiology · doi:10.1016/j.mib.2014.11.009 · Cited by 99 · see citing works

Nematodes: an overlooked tiny engineer of plant health

Li, G., Liu, T., Whalen, J. K., & Wei, Z. (2023) · Trends in Plant Science · doi:10.1016/j.tplants.2023.06.022 · Cited by 99 · see citing works

Whole Animal Automated Platform for Drug Discovery against Multi-Drug Resistant Staphylococcus aureus

Rajamuthiah, R., Fuchs, B. B., Jayamani, E., Kim, Y., Larkins‐Ford, J., Conery, A. L., Ausubel, F. M., & Mylonakis, E. E. (2014) · PLoS ONE · doi:10.1371/journal.pone.0089189 · Cited by 95 · see citing works

Interplay between mitochondria and diet mediates pathogen and stress resistance in Caenorhabditis elegans

Revtovich, A. V., Lee, R. Y., & Kirienko, N. V. (2019) · PLoS Genetics · doi:10.1371/journal.pgen.1008011 · Cited by 94 · see citing works

Biopesticides produced by plant-probiotic Pseudomonas chlororaphis isolates

Anderson, A. J., & Kim, Y. C. (2017) · Crop Protection · doi:10.1016/j.cropro.2017.11.009 · Cited by 90 · see citing works

Host-microbe interactions and the behavior of Caenorhabditis elegans

Kim, D. H., & Flavell, S. W. (2020) · Journal of Neurogenetics · doi:10.1080/01677063.2020.1802724 · Cited by 87 · see citing works

Discovery of potential anti-infectives against Staphylococcus aureus using a Caenorhabditis elegans infection model

Kong, C., Yehye, W. A., Rahman, N. A., Tan, M., & Nathan, S. (2014) · BMC Complementary and Alternative Medicine · doi:10.1186/1472-6882-14-4 · Cited by 84 · see citing works

A Novel Activation Mechanism of Avian Influenza Virus H9N2 by Furin

Tse, L. V., Hamilton, A. M., Friling, T., & Whittaker, G. R. (2013) · Journal of Virology · doi:10.1128/jvi.02648-13 · Cited by 84 · see citing works

Identification of an Antimicrobial Agent Effective against Methicillin-Resistant Staphylococcus aureus Persisters Using a Fluorescence-Based Screening Strategy

Kim, W., Conery, A. L., Rajamuthiah, R., Fuchs, B. B., Ausubel, F. M., & Mylonakis, E. E. (2015) · PLoS ONE · doi:10.1371/journal.pone.0127640 · Cited by 75 · see citing works

Insect-Derived Cecropins Display Activity against Acinetobacter baumannii in a Whole-Animal High-Throughput Caenorhabditis elegans Model

Jayamani, E., Rajamuthiah, R., Larkins‐Ford, J., Fuchs, B. B., Conery, A. L., Vilcinskas, A., Ausubel, F. M., & Mylonakis, E. E. (2015) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.04198-14 · Cited by 72 · see citing works

Rhizosphere pseudomonads as probiotics improving plant health

Kim, Y. C., & Anderson, A. J. (2018) · Molecular Plant Pathology · doi:10.1111/mpp.12693 · Cited by 72 · see citing works

Iron acquisition strategies in pseudomonads: mechanisms, ecology, and evolution

Kümmerli, R. (2022) · BioMetals · doi:10.1007/s10534-022-00480-8 · Cited by 65 · see citing works

Novel Pyoverdine Inhibitors Mitigate Pseudomonas aeruginosa Pathogenesis

Kirienko, D. R., Kang, D., & Kirienko, N. V. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.03317 · Cited by 67 · see citing works

Vanillin inhibits PqsR-mediated virulence in Pseudomonas aeruginosa

Mok, N., Chan, S. Y., Liu, S. Y., & Chua, S. L. (2020) · Food & Function · doi:10.1039/d0fo00046a · Cited by 66 · see citing works

High-Throughput Genetic Screen Reveals that Early Attachment and Biofilm Formation Are Necessary for Full Pyoverdine Production by Pseudomonas aeruginosa

Kang, D., & Kirienko, N. V. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.01707 · Cited by 62 · see citing works

A Dual-Specificity Inhibitor Targets Polyphosphate Kinase 1 and 2 Enzymes To Attenuate Virulence of Pseudomonas aeruginosa

Neville, N., Roberge, N. A., Ji, X. L., Stephen, P., Lu, J., & Jia, Z. (2021) · mBio · doi:10.1128/mbio.00592-21 · Cited by 59 · see citing works

Novel therapeutic strategies for treatingPseudomonas aeruginosainfection

Shao, X., Xie, Y., Zhang, Y., Liu, J., Ding, Y., Wu, M., Wang, X., & Deng, X. (2020) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2020.1803274 · Cited by 58 · see citing works

A High-Content, Phenotypic Screen Identifies Fluorouridine as an Inhibitor of Pyoverdine Biosynthesis and Pseudomonas aeruginosa Virulence

Kirienko, D. R., Revtovich, A. V., & Kirienko, N. V. (2016) · mSphere · doi:10.1128/msphere.00217-16 · Cited by 56 · see citing works

PqsA Promotes Pyoverdine Production via Biofilm Formation

Kang, D., Turner, K., & Kirienko, N. V. (2017) · Pathogens · doi:10.3390/pathogens7010003 · Cited by 56 · see citing works

Caenorhabditis elegans in high-throughput screens for anti-infective compounds

Peterson, N., & Pukkila-Worley, R. (2018) · Current Opinion in Immunology · doi:10.1016/j.coi.2018.06.003 · Cited by 53 · see citing works

Bacteria and bacterial products: Foe and friends to Caenorhabditis elegans

Khan, F., Jain, S., & Oloketuyi, S. F. (2018) · Microbiological Research · doi:10.1016/j.micres.2018.06.012 · Cited by 54 · see citing works

Choosing an Appropriate Infection Model to Study Quorum Sensing Inhibition in Pseudomonas Infections

Papaioannou, E., Utari, P. D., & Quax, W. J. (2013) · International Journal of Molecular Sciences · doi:10.3390/ijms140919309 · Cited by 52 · see citing works

Caenorhabditis elegans susceptibility to gut Enterococcus faecalis infection is associated with fat metabolism and epithelial junction integrity

Sim, S., & Hibberd, M. L. (2016) · BMC Microbiology · doi:10.1186/s12866-016-0624-8 · Cited by 45 · see citing works

Beyond Traditional Antimicrobials: A Caenorhabditis elegans Model for Discovery of Novel Anti-infectives

Kong, C., Eng, S.-A., Lim, M.-P., & Nathan, S. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01956 · Cited by 48 · see citing works

High‐Throughput Screening for Novel Anti‐Infectives Using a C. elegans Pathogenesis Model

Conery, A. L., Larkins‐Ford, J., Ausubel, F. M., & Kirienko, N. V. (2014) · Current Protocols in Chemical Biology · doi:10.1002/9780470559277.ch130160 · Cited by 47 · see citing works

A conserved mitochondrial surveillance pathway is required for defense against Pseudomonas aeruginosa

Tjahjono, E., & Kirienko, N. V. (2017) · PLoS Genetics · doi:10.1371/journal.pgen.1006876 · Cited by 46 · see citing works

Biofilm matrix disrupts nematode motility and predatory behavior

Chan, S. Y., Liu, S. Y., Seng, Z., & Chua, S. L. (2020) · The ISME Journal · doi:10.1038/s41396-020-00779-9 · Cited by 46 · see citing works

A pathogen branched-chain amino acid catabolic pathway subverts host survival by impairing energy metabolism and the mitochondrial UPR

Mahmud, S. A., Qureshi, M. A., Sapkota, M., & Pellegrino, M. W. (2020) · PLoS Pathogens · doi:10.1371/journal.ppat.1008918 · Cited by 46 · see citing works

Role of GATA transcription factor ELT-2 and p38 MAPK PMK-1 in recovery from acuteP. aeruginosainfection inC. elegans

Head, B. P., Olaitan, A. O., & Aballay, A. (2016) · Virulence · doi:10.1080/21505594.2016.1222334 · Cited by 45 · see citing works

Mitochondrial dysfunction, aging, and the mitochondrial unfolded protein response in Caenorhabditis elegans

Haynes, C. M., & Hekimi, S. (2022) · Genetics · doi:10.1093/genetics/iyac160 · Cited by 45 · see citing works

Design and Synthesis of 3-Hydroxy-pyridin-4(1 H )-ones–Ciprofloxacin Conjugates as Dual Antibacterial and Antibiofilm Agents against Pseudomonas aeruginosa

Wang, Y., Zhang, X., Zhong, X.-L., Huang, Y.-J., Lin, J., & Chen, W. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.2c02044 · Cited by 44 · see citing works

Do Bacterial “Virulence Factors” Always Increase Virulence? A Meta-Analysis of Pyoverdine Production in Pseudomonas aeruginosa As a Test Case

Granato, E. T., Harrison, F., Kümmerli, R., & Ross‐Gillespie, A. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.01952 · Cited by 43 · see citing works

An update on the use ofC. elegansfor preclinical drug discovery: screening and identifying anti-infective drugs

Kim, W., Hendricks, G. L., Lee, K., & Mylonakis, E. E. (2017) · Expert Opinion on Drug Discovery · doi:10.1080/17460441.2017.1319358 · Cited by 43 · see citing works

Evidence for Complex Interplay between Quorum Sensing and Antibiotic Resistance in Pseudomonas aeruginosa

Sikdar, R., & Elias, M. H. (2022) · Microbiology Spectrum · doi:10.1128/spectrum.01269-22 · Cited by 43 · see citing works

Global Proteomics Revealed Klebsiella pneumoniae Induced Autophagy and Oxidative Stress in Caenorhabditis elegans by Inhibiting PI3K/AKT/mTOR Pathway during Infection

Kamaladevi, A., & Balamurugan, K. (2017) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2017.00393 · Cited by 43 · see citing works

Protective Liquid Crystal Nanoparticles for Targeted Delivery of PslG: A Biofilm Dispersing Enzyme

Thorn, C. R., Raju, D., Lacdao, I., Gilbert, S., Sivarajah, P., Howell, P. L., Prestidge, C. A., & Thomas, N. (2021) · ACS Infectious Diseases · doi:10.1021/acsinfecdis.1c00014 · Cited by 43 · see citing works

6-Methylcoumarin attenuates quorum sensing and biofilm formation in Pseudomonas aeruginosa PAO1 and its applications on solid surface coatings with polyurethane

Bajire, S. K., Jain, S., Johnson, R. P., & Shastry, R. P. (2021) · Applied Microbiology and Biotechnology · doi:10.1007/s00253-021-11637-9 · Cited by 39 · see citing works

Novel Insights on Pyoverdine: From Biosynthesis to Biotechnological Application

Dell’Anno, F., Vitale, G. A., Buonocore, C., Vitale, L. A., Esposito, F. P., Coppola, D., Sala, G. D., Tedesco, P., & de Pascale, D. (2022) · International Journal of Molecular Sciences · doi:10.3390/ijms231911507 · Cited by 38 · see citing works

Comprehensive genetic analysis of adhesin proteins and their role in virulence ofCandida albicans

Rosiana, S., Zhang, L., Kim, G. H., Revtovich, A. V., Uthayakumar, D., Sukumaran, A., Geddes‐McAlister, J., Kirienko, N. V., & Shapiro, R. S. (2021) · Genetics · doi:10.1093/genetics/iyab003 · Cited by 36 · see citing works

Nematode-Trapping Fungi Produce Diverse Metabolites during Predator–Prey Interaction

Kuo, T.-H., Yang, C.-T., Chang, H.-Y., Hsueh, Y., & Hsu, C. (2020) · Metabolites · doi:10.3390/metabo10030117 · Cited by 37 · see citing works

In-vivo microscopy reveals the impact of Pseudomonas aeruginosa social interactions on host colonization

Rezzoagli, C., Granato, E. T., & Kümmerli, R. (2019) · The ISME Journal · doi:10.1038/s41396-019-0442-8 · Cited by 31 · see citing works

Bacterial Metabolites Produced Under Iron Limitation Kill Pinewood Nematode and Attract Caenorhabditis elegans

Proença, D. N., Heine, T., Senges, C. H. R., Bandow, J. E., Morais, P. V., & Tischler, D. (2019) · Frontiers in Microbiology · doi:10.3389/fmicb.2019.02166 · Cited by 34 · see citing works

Treatment with paeoniflorin increases lifespan of Pseudomonas aeruginosa infected Caenorhabditis elegans by inhibiting bacterial accumulation in intestinal lumen and biofilm formation

Wang, Y., Zhang, L., Yuan, X., & Wang, D. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1114219 · Cited by 33 · see citing works

An In Vitro Cell Culture Model for Pyoverdine-Mediated Virulence

Kang, D., & Kirienko, N. V. (2020) · Pathogens · doi:10.3390/pathogens10010009 · Cited by 33 · see citing works

3-Hydroxypyridin-4(1H)-one Derivatives as pqs Quorum Sensing Inhibitors Attenuate Virulence and Reduce Antibiotic Resistance in Pseudomonas aeruginosa

Miao, Z.-Y., Zhang, X., Yang, M.-H., Huang, Y.-J., Lin, J., & Chen, W. (2023) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.3c01328 · Cited by 32 · see citing works

A High-throughput, High-content, Liquid-based C. elegans Pathosystem

Anderson, Q. L., Revtovich, A. V., & Kirienko, N. V. (2018) · Journal of Visualized Experiments · doi:10.3791/58068 · Cited by 31 · see citing works

Hypoxia-inducible factor cell non-autonomously regulates C. elegans stress responses and behavior via a nuclear receptor

Pender, C. L., & Horvitz, H. R. (2018) · eLife · doi:10.7554/elife.36828 · Cited by 28 · see citing works

Novel Immune Modulators Enhance Caenorhabditis elegans Resistance to Multiple Pathogens

Hummell, N. A., Revtovich, A. V., & Kirienko, N. V. (2021) · mSphere · doi:10.1128/msphere.00950-20 · Cited by 29 · see citing works

Caenorhabditis elegans reveals novel Pseudomonas aeruginosa virulence mechanism

Utari, P. D., & Quax, W. J. (2013) · Trends in Microbiology · doi:10.1016/j.tim.2013.04.006 · Cited by 29 · see citing works

The Pathogenicity of Pseudomonas syringae MB03 against Caenorhabditis elegans and the Transcriptional Response of Nematicidal Genes upon Different Nutritional Conditions

Ali, M., Sun, Y., Xie, L., Yu, H., Bashir, A., & Li, L. (2016) · Frontiers in Microbiology · doi:10.3389/fmicb.2016.00805 · Cited by 28 · see citing works

Bacterial communities protect the alga Microchloropsis salina from grazing by the rotifer Brachionus plicatilis

Fisher, C. L., Ward, C. S., Lane, P. D., Kimbrel, J. A., Sale, K. L., Stuart, R. K., Mayali, X., & Lane, T. W. (2019) · Algal Research · doi:10.1016/j.algal.2019.101500 · Cited by 28 · see citing works

High-throughput small molecule screen identifies inhibitors of microsporidia invasion and proliferation in C. elegans

Murareanu, B. M., Antao, N. V., Zhao, W., Dubuffet, A., Alaoui, H. E., Knox, J. J., Ekiert, D. C., Bhabha, G., Roy, P. J., & Reinke, A. W. (2022) · Nature Communications · doi:10.1038/s41467-022-33400-y · Cited by 28 · see citing works

Pyoverdine Inhibitors and Gallium Nitrate Synergistically Affect Pseudomonas aeruginosa

Kang, D., Revtovich, A. V., Deyanov, A. E., & Kirienko, N. V. (2021) · mSphere · doi:10.1128/msphere.00401-21 · Cited by 27 · see citing works

Understanding the Potential and Risk of Bacterial Siderophores in Cancer

Pita-Grisanti, V., Chasser, K. M., Sobol, T., & Cruz‐Monserrate, Z. (2022) · Frontiers in Oncology · doi:10.3389/fonc.2022.867271 · Cited by 28 · see citing works

Lysosomal dysfunction by inactivation of V-ATPase drives innate immune response in C. elegans

Pu, X., & Qi, B. (2024) · Cell Reports · doi:10.1016/j.celrep.2024.114138 · Cited by 24 · see citing works

Mechanisms controlling bacterial infection in myeloid cells under hypoxic conditions

Hayek, I., Schatz, V., Bogdan, C., Jantsch, J., & Lührmann, A. (2020) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-020-03684-8 · Cited by 24 · see citing works

Shigella flexneri Infection in Caenorhabditis elegans: Cytopathological Examination and Identification of Host Responses

George, D. T., Behm, C. A., Hall, D. H., Mathesius, U., Rug, M., Nguyen, K. C. Q., & Verma, N. K. (2014) · PLoS ONE · doi:10.1371/journal.pone.0106085 · Cited by 25 · see citing works

The evolutionarily conserved ESRE stress response network is activated by ROS and mitochondrial damage

Tjahjono, E., McAnena, A. P., & Kirienko, N. V. (2020) · BMC Biology · doi:10.1186/s12915-020-00812-5 · Cited by 23 · see citing works

Iron Acquisition and Metabolism as a Promising Target for Antimicrobials (Bottlenecks and Opportunities): Where Do We Stand?

Stelitano, G., Cocorullo, M., Mori, M., Villa, S., Meneghetti, F., & Chiarelli, L. R. (2023) · International Journal of Molecular Sciences · doi:10.3390/ijms24076181 · Cited by 23 · see citing works

Effect of Anaerobiasis or Hypoxia on Pseudomonas aeruginosa Inhibition of Aspergillus fumigatus Biofilm

Anand, R., Clemons, K. V., & Stevens, D. A. (2017) · Archives of Microbiology · doi:10.1007/s00203-017-1362-5 · Cited by 23 · see citing works

A novel gene-diet interaction promotes organismal lifespan and host protection during infection via the mitochondrial UPR

Amin, M. R., Mahmud, S. A., Dowgielewicz, J., Sapkota, M., & Pellegrino, M. W. (2020) · PLoS Genetics · doi:10.1371/journal.pgen.1009234 · Cited by 22 · see citing works

High-Throughput Approaches for the Identification of Pseudomonas aeruginosa Antivirulents

Kang, D., Zhang, L., & Kirienko, N. V. (2021) · mBio · doi:10.1128/mbio.02240-20 · Cited by 21 · see citing works

Ubiquitin-related processes and innate immunity in C. elegans

Garcia-Sanchez, J. A., Ewbank, J. J., & Visvikis, O. (2021) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-021-03787-w · Cited by 21 · see citing works

Pathogenesis of plant-associated Pseudomonas aeruginosa in Caenorhabditis elegans model

Ambreetha, S., & Balachandar, D. (2022) · BMC Microbiology · doi:10.1186/s12866-022-02682-z · Cited by 20 · see citing works

Emerging strategies to target virulence in Pseudomonas aeruginosa respiratory infections

Hibbert, T. M., Whiteley, M., Renshaw, S. A., Neill, D. R., & Fothergill, J. L. (2023) · Critical Reviews in Microbiology · doi:10.1080/1040841x.2023.2285995 · Cited by 20 · see citing works

The Nif3-Family Protein YqfO03 from Pseudomonas syringae MB03 Has Multiple Nematicidal Activities against Caenorhabditis elegans and Meloidogyne incognita

Manan, A., Bazai, Z. A., Jin, F., Yu, H., & Li, L. (2018) · International Journal of Molecular Sciences · doi:10.3390/ijms19123915 · Cited by 20 · see citing works

Caenorhabditis elegans as an Infection Model for Pathogenic Mold and Dimorphic Fungi: Applications and Challenges

Ahamefule, C. S., Ezeuduji, B. C., Ogbonna, J. C., Moneke, A. N., Ike, A. C., Jin, C., Wang, B., & Fang, W. (2021) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2021.751947 · Cited by 19 · see citing works

Liquid crystal nanoparticle platform for increased efficacy of cationic antimicrobials against biofilm infections

Thorn, C. R., Kopecki, Z., Wignall, A. D., Kral, A., Prestidge, C. A., & Thomas, N. (2022) · Nanomedicine Nanotechnology Biology and Medicine · doi:10.1016/j.nano.2022.102536 · Cited by 19 · see citing works

To eat or not to eat mitochondria? How do host cells cope with mitophagy upon bacterial infection?

Verbeke, J., Bolle, X. D., & Arnould, T. (2023) · PLoS Pathogens · doi:10.1371/journal.ppat.1011471 · Cited by 19 · see citing works

Genetics of Immune Recognition and Response in Drosophila host defense

Ligoxygakis, P. (2013) · Advances in genetics · doi:10.1016/b978-0-12-407675-4.00002-x · Cited by 19 · see citing works

Feeding behaviour of Caenorhabditis elegans is an indicator of Pseudomonas aeruginosa PAO1 virulence

Lewenza, S., Charron‐Mazenod, L., Giroux, L., & Zamponi, A. (2014) · PeerJ · doi:10.7717/peerj.521 · Cited by 19 · see citing works

Association with pathogenic bacteria affects life‐history traits and population growth in Caenorhabditis elegans

Díaz, S. A., Mooring, E. Q., Rens, E. G., & Restif, O. (2015) · Ecology and Evolution · doi:10.1002/ece3.1461 · Cited by 18 · see citing works

Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa

Kirienko, N. V., Ausubel, F. M., & Ruvkun, G. (2015) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1424954112 · Cited by 197 · see citing works

Red death in Caenorhabditis elegans caused by Pseudomonas aeruginosa PAO1

Zaborin, A., Romanowski, K. S. S., Gerdes, S., Holbrook, C., Lepine, F. L., Long, J., Poroyko, V. A., Diggle, S. P., Wilke, A., Righetti, K., et al. (2009) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0813199106 · Cited by 220 · see citing works

Pyoverdine, a siderophore from Pseudomonas aeruginosa , translocates into C. elegans , removes iron, and activates a distinct host response

Kang, D., Kirienko, D. R., Webster, P. J., Fisher, A. L., & Kirienko, N. V. (2018) · Virulence · doi:10.1080/21505594.2018.1449508 · Cited by 159 · see citing works

Distinct Pathogenesis and Host Responses during Infection of C. elegans by P. aeruginosa and

Irazoqui, J. E., Troemel, E. R., Feinbaum, R. L., Luhachack, L. G., Cezairliyan, B. O., & Ausubel, F. M. (2013)

Molecular Mechanisms of Bacterial Virulence Elucidated Using a Pseudomonas aeruginosa– Caenorhabditis elegans Pathogenesis Model

Mahajan‐Miklos, S., Tan, M., Rahme, L. G., & Ausubel, F. M. (1999) · Cell · doi:10.1016/s0092-8674(00)80958-7 · Cited by 821 · see citing works