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Cited by 70Fermentation and Sensory AnalysisAnalytical chemistry methods developmentPhytochemicals and Antioxidant Activities

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Identification and quantification of 56 targeted phenols in wines, spirits, and vinegars by online solid-phase extraction – ultrahigh-performance liquid chromatography – quadrupole-orbitrap mass spectrometry

Barnaba, C., Dellacassa, E., Nicolini, G., Nardin, T., Malacarne, M., Larcher, R.·2015·Journal of Chromatography A
DOI 10.1016/j.chroma.2015.10.085
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Abstract

Phenolic compounds seriously affect the sensory and nutritional qualities of food products, both through the positive contribution of wood transfer in barrel-aged products and as off-flavours. A new targeted analytical approach combining on-line solid-phase extraction (SPE) clean-up to reduce matrix interference and rapid chromatographic detection performed with ultrahigh-performance liquid chromatography coupled with quadrupole/high-resolution mass spectrometry (Q-Orbitrap), was developed for the quantification of 56 simple phenols. Considering the advantages of using on-line SPE and a resolving power of 140,000, the proposed method was applied to define phenolic content in red (N=8) and white (8) wines, spirits (8), common (8) and balsamic (8) vinegars. The final method was linear from the limits of quantification (0.0001-0.001μgmL(-1)) up to 10μgmL(-1) with R(2) of at least 0.99. Recovery, used to define method accuracy, ranged from 80 to 120% for 89% of compounds. The method was suitable for analytical requirements in the tested matrices being able to analyse 46 phenols in red wines, 41 phenols in white wines and in spirits, 42 phenols in common vinegars and 44 phenols in balsamic vinegars.

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Metadata

Authors
Barnaba, C., Dellacassa, E., Nicolini, G., Nardin, T., Malacarne, M., & Larcher, R.
Affiliations
  • Fondazione Edmund Mach (IT)
  • Universidad de la República de Uruguay (UY)
Corresponding author
Larcher, R.
ORCID
Venue
Journal of Chromatography A
Publisher
Elsevier BV
Published
2015-12
Volume
1423
Pages
124-135
ISSN
0021-9673 (ISSN-L)
DOI
10.1016/j.chroma.2015.10.085
OpenAlex
W1909346774
Cited by
70
References
0
Citations by year
2026: 2 · 2025: 6 · 2024: 6 · 2023: 7 · 2022: 6 · 2021: 5 · 2020: 5 · 2019: 9 · 2018: 6 · 2017: 12 · 2016: 6
FWCI
9.91
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Journal of Chromatography A (publishedVersion)
  • PubMed (publishedVersion)
  • CINECA IRIS Institutional Research Information System (Fondazione Edmund Mach) (submittedVersion)
Topics
  • Life Sciences › Agricultural and Biological Sciences › Food Science › Fermentation and Sensory Analysis
  • Physical Sciences › Chemistry › Analytical Chemistry › Analytical chemistry methods development
  • Health Sciences › Medicine › Biochemistry (medical) › Phytochemicals and Antioxidant Activities
Keywords
phenolic compounds, simple phenols, wine, alcoholic beverages, vinegar, balsamic vinegar, red wine, white wine, on-line solid-phase extraction, targeted analysis, barrel aging, off-flavor
MeSH terms
Alcoholic Beverages, Chromatography, Liquid, Food Analysis, Phenols, Mass Spectrometry, Wine, Acetic Acid, Solid Phase Extraction

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