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Cited by 132Deep Brain Stimulation and Movement DisordersBotulinum Toxin and Related Neurological DisordersObsessive-Compulsive Spectrum Disorders

The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.

Quality of life in patients with focal dystonia

Pekmezovic, Tatjana, Svetel, Marina, Ivanovic, Natasa, Dragasevic, Natasa, Petrovic, Igor, Tepavcevic, Darija Kisic, Kostic, Vladimir S.·2009·Clinical Neurology and Neurosurgery
DOI 10.1016/j.clineuro.2008.09.023
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Abstract

Objectives The aims of this study were to identify the clinical and demographic factors influencing health-related quality of life (HR-QoL) and to compare HR-QoL measures between various types of focal dystonia (cervical dystonia, blepharospasm, and writer's cramp).Methods We examined 157 consecutive patients with adult-onset primary focal dystonia, and HR-QoL was assessed by using the SF-36 questionnaire. Univariate and multivariate regression analyses were performed.Results Patients with writer's cramp scored better in all SF-36 domains, except role functioning physical (RP), while these differences were statistically significant for physical functioning (PF) (p=0.020), bodily pain (BP) (p=0.001), and general health (GH) (p=0.004). Patients with writer's cramp and blepharospasm scored significantly better for BP (p=0.001) than patients with cervical dystonia. We found that each of the eight dimensions of SF-36 proved to be significantly correlated to the Hamilton depression rating scale score in patients with torticollis and blepharospasm, while vitality (VT), social functioning (SF), and mental health (MH) scales showed statistically significant correlations in patients with hand dystonia. Similar relationships were observed between anxiety and SF-36 domains.Conclusion Depression and anxiety are the most important predictors of poorer HR-QoL in patients with all three types of focal dystonia.

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Crossref · 10.1016/j.clineuro.2008.09.023

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Metadata

Authors
Pekmezovic, T., Svetel, M., Ivanovic, N., Dragasevic, N., Petrovic, I., Tepavcevic, D. K., & Kostic, V. S.
Affiliations
Univerzitetski Klinički Centar Srbije (RS)
ORCID
Venue
Clinical Neurology and Neurosurgery
Publisher
Elsevier BV
Published
2009-02
Volume
111
Issue
2
Pages
161-164
ISSN
0303-8467 (ISSN-L)
DOI
10.1016/j.clineuro.2008.09.023
OpenAlex
W2011528262
Cited by
132
References
25
Citations by year
2026: 2 · 2025: 6 · 2024: 3 · 2023: 1 · 2022: 16 · 2021: 7 · 2020: 19 · 2019: 11 · 2018: 11 · 2017: 12 · 2016: 9 · 2015: 3 · 2014: 6 · 2013: 8 · 2012: 6
FWCI
2.54
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Clinical Neurology and Neurosurgery (publishedVersion)
  • PubMed (publishedVersion)
Funders
  • Science and Engineering Research Board
  • NIH Clinical Center
Topics
  • Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
  • Health Sciences › Medicine › Clinical Neurology › Botulinum Toxin and Related Neurological Disorders
  • Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
Keywords
focal dystonia, health-related quality of life, cervical dystonia, blepharospasm, writer's cramp, SF-36, depression, anxiety, bodily pain, physical function, hand dystonia, torticollis
MeSH terms
Adult, Aged, Blepharospasm, Depression, Female, Health Status, Humans, Male, Mental Health, Middle Aged, Pain, Psychiatric Status Rating Scales, Quality of Life, Surveys and Questionnaires, Regression Analysis, Severity of Illness Index, Social Adjustment, Torticollis, Dystonic Disorders

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