The DOI matches its Crossref record; 26 of the 26 references it cites were found in a registry or an index.
Quality of life in patients with focal dystonia
Abstract
Objectives The aims of this study were to identify the clinical and demographic factors influencing health-related quality of life (HR-QoL) and to compare HR-QoL measures between various types of focal dystonia (cervical dystonia, blepharospasm, and writer's cramp).Methods We examined 157 consecutive patients with adult-onset primary focal dystonia, and HR-QoL was assessed by using the SF-36 questionnaire. Univariate and multivariate regression analyses were performed.Results Patients with writer's cramp scored better in all SF-36 domains, except role functioning physical (RP), while these differences were statistically significant for physical functioning (PF) (p=0.020), bodily pain (BP) (p=0.001), and general health (GH) (p=0.004). Patients with writer's cramp and blepharospasm scored significantly better for BP (p=0.001) than patients with cervical dystonia. We found that each of the eight dimensions of SF-36 proved to be significantly correlated to the Hamilton depression rating scale score in patients with torticollis and blepharospasm, while vitality (VT), social functioning (SF), and mental health (MH) scales showed statistically significant correlations in patients with hand dystonia. Similar relationships were observed between anxiety and SF-36 domains.Conclusion Depression and anxiety are the most important predictors of poorer HR-QoL in patients with all three types of focal dystonia.
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“Psychiatric difficulties have been shown to have an impact on both psychological and physical QoL, which in some cases is greater than the cervical dystonia motor severity [6, 37].”
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The non-motor syndrome of primary dystonia: clinical and pathophysiological implications
Stamelou, M., Edwards, M. J., Hallett, M., & Bhatia, K. P. (2012) · Brain · doi:10.1093/brain/awr224 · Cited by 299
The focal dystonias: Current views and challenges for future research
Jinnah, H. A., Berardelli, A., Comella, C., Defazio, G., DeLong, M. R., Factor, S. A., Galpern, W. R., Hallett, M., Ludlow, C. L., Perlmutter, J. S., et al. (2013) · Movement Disorders · doi:10.1002/mds.25567 · Cited by 210
Psychiatric disorders in adult‐onset focal dystonia: A case‐control study
Fabbrini, G., Berardelli, I., Moretti, G., Pasquini, M., Bloise, M. C., Colosimo, C., Biondi, M., & Berardelli, A. (2010) · Movement Disorders · doi:10.1002/mds.22983 · Cited by 193
Psychiatric comorbidities in dystonia: Emerging concepts
Zurowski, M., McDonald, W. M., Fox, S. H., & Marsh, L. (2013) · Movement Disorders · doi:10.1002/mds.25501 · Cited by 113
An international survey of patients with cervical dystonia
Comella, C., & Bhatia, K. P. (2015) · Journal of Neurology · doi:10.1007/s00415-014-7586-2 · Cited by 107
Metadata
- Authors
- Pekmezovic, T., Svetel, M., Ivanovic, N., Dragasevic, N., Petrovic, I., Tepavcevic, D. K., & Kostic, V. S.
- Affiliations
- Univerzitetski Klinički Centar Srbije (RS)
- Venue
- Clinical Neurology and Neurosurgery
- Publisher
- Elsevier BV
- Published
- 2009-02
- Volume
- 111
- Issue
- 2
- Pages
- 161-164
- ISSN
- 0303-8467 (ISSN-L)
- OpenAlex
- W2011528262
- Cited by
- 132
- References
- 25
- Citations by year
- 2026: 2 · 2025: 6 · 2024: 3 · 2023: 1 · 2022: 16 · 2021: 7 · 2020: 19 · 2019: 11 · 2018: 11 · 2017: 12 · 2016: 9 · 2015: 3 · 2014: 6 · 2013: 8 · 2012: 6
- FWCI
- 2.54
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Clinical Neurology and Neurosurgery (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Science and Engineering Research Board
- NIH Clinical Center
- Topics
- Health Sciences › Medicine › Clinical Neurology › Deep Brain Stimulation and Movement Disorders
- Health Sciences › Medicine › Clinical Neurology › Botulinum Toxin and Related Neurological Disorders
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Keywords
- focal dystonia, health-related quality of life, cervical dystonia, blepharospasm, writer's cramp, SF-36, depression, anxiety, bodily pain, physical function, hand dystonia, torticollis
- MeSH terms
- Adult, Aged, Blepharospasm, Depression, Female, Health Status, Humans, Male, Mental Health, Middle Aged, Pain, Psychiatric Status Rating Scales, Quality of Life, Surveys and Questionnaires, Regression Analysis, Severity of Illness Index, Social Adjustment, Torticollis, Dystonic Disorders
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