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Cited by 59Phytochemicals and Antioxidant ActivitiesDiet, Metabolism, and DiseaseNutritional Studies and Diet

Variations on Cardiovascular Risk Factors in Metabolic Syndrome after Consume of a Citrus-Based Juice

Mulero, Juana, Bernabé, Juana, Cerdá, Begoña, García-Viguera, Cristina, Moreno, Diego A., Albaladejo, Ma Dolores, Avilés, Francisco, Parra, Soledad +2 more·2012·Clinical Nutrition
DOI 10.1016/j.clnu.2011.11.014
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Abstract

Background & aims Inflammation and oxidative stress plays a critical role in cardiovascular disease and metabolic syndrome often occurs with these two variables. The aim of the study is to estimate variations on cardiovascular risk factors in Metabolic Syndrome patients after consume of a citrus-based juice compared with control groups.Methods The study comprised 20 healthy subjects and 33 patients with Metabolic Syndrome. 18 patients consume daily 300 mL of a citrus-based juice during 6 month and 15 patients consume 300 mL of a placebo beverage. The control group consumes a citrus-based juice. Before, at fourth month and at sixth month after treatment the following parameters were determined: lipid profile, oxidized LDL, C-Reactive Protein and Homocysteine. The study was carried out in accordance with the Helsinki Declaration, and the Ethical Committee of the San Antonio Catholic University and approved the protocol (6 November 2006, register number: 1424).Results After six months of citrus-based juice consuming, there is significant differences at 95% confidence in oxidized LDL, C-Reactive Protein, and Homocysteine in Metabolic Syndrome patients who consume citrus-based juice. We have not found significant differences in other groups.Conclusions Consume of citrus-based juice improve lipid profile and inflammation markers in Metabolic Syndrome patients.

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Crossref · 10.1016/j.clnu.2011.11.014

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  • Hesperidin attenuates senescence-related oxidative damage in cardiomyocytes, both independently and in combination with other molecules, through induction of Nrf2 and GST expression.

    “Its properties impact positively on cardiomyocytes as it attenuates senescence-related oxidative damage, both independently and in combination with other molecules, through the induction of Nrf2 and of GST expression [247,296,297].”

    From The Role of Antioxidants in the Interplay between Oxidative Stress and Senescence (2022) · cites this paper as [297]

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Authors
Mulero, J., Bernabé, J., Cerdá, B., García-Viguera, C., Moreno, D. A., Albaladejo, M. D., Avilés, F., Parra, S., Abellán, J., & Zafrilla, P.
Affiliations
  • Universidad Católica de Murcia (ES)
  • Consejo Superior de Investigaciones Científicas (ES)
  • Hospital Universitario Virgen de la Arrixaca (ES)
Corresponding author
Mulero, Juana
ORCID
Venue
Clinical Nutrition
Publisher
Elsevier BV
Published
2012-06
Volume
31
Issue
3
Pages
372-377
ISSN
0261-5614 (ISSN-L)
DOI
10.1016/j.clnu.2011.11.014
OpenAlex
W2097615867
Cited by
59
References
30
Citations by year
2025: 1 · 2024: 3 · 2023: 2 · 2022: 5 · 2021: 6 · 2020: 5 · 2019: 7 · 2018: 3 · 2017: 7 · 2016: 8 · 2015: 2 · 2014: 5 · 2013: 3 · 2012: 2
FWCI
2.09
Type
journal article
Language
en
Open access
closed
Licence
www.elsevier.com/tdm/userlicense/1.0/ (tdm)
Locations
  • Clinical Nutrition (publishedVersion)
  • PubMed (publishedVersion)
Funders
Comisión Interministerial de Ciencia y Tecnología (CICYT)
Topics
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diet, Metabolism, and Disease
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
metabolic syndrome, citrus juice, cardiovascular risk factors, inflammation, oxidative stress, oxidized LDL, C-reactive protein, homocysteine, lipid profile, dietary intervention
MeSH terms
Aged, Antioxidants, Beverages, C-Reactive Protein, Cardiovascular Diseases, Citrus, Female, Fruit, Homocysteine, Humans, Lipoproteins, LDL, Male, Middle Aged, Plant Extracts, Risk Factors, Spain, Time Factors, Lipid Peroxidation, Metabolic Syndrome, Photinia

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