Cited by 173Regulation of Appetite and ObesityAdipokines, Inflammation, and Metabolic DiseasesCytokine Signaling Pathways and Interactions

The DOI matches its Crossref record; 48 of the 48 references it cites were found in a registry or an index.

Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

Open access

Bates, Sarah H., Kulkarni, Rohit N., Seifert, Matthew, Myers, Martin G.·2005·Cell Metabolism

DOI 10.1016/j.cmet.2005.02.001

Open this paper in CoChat — free account Open PDF

Abstract

Leptin activates the long form of the leptin receptor (LRb) to control feeding and neuroendocrine function and thus regulate adiposity. While adiposity influences insulin sensitivity, leptin also regulates glucose homeostasis independently of energy balance. Disruption of the LRb/STAT3 signal in s/s mice results in hyperphagia, neuroendocrine dysfunction, and obesity similar to LRb null db/db mice. Insulin resistance and glucose intolerance are improved in s/s compared to db/db animals, however, suggesting that LRb/STAT3-independent signals may contribute to the regulation of glucose homeostasis by leptin. Indeed, caloric restriction normalized glycemic control in s/s animals, but db/db mice of similar weight and adiposity remained hyperglycemic. These differences in glucose homeostasis were not attributable to differences in insulin production between s/s and db/db animals but rather to decreased insulin resistance in s/s mice. Thus, in addition to LRb/STAT3-mediated adiposity signals, non-LRb/STAT3 leptin signals mediate an important adiposity-independent role in promoting glycemic control.

Integrity signals

Registry

Crossref · 10.1016/j.cmet.2005.02.001

Cites

48 of 48 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

Positional cloning of the mouse obese gene and its human homologue
Zhang, Y., Proenca, R., Maffei, M., Barone, M., Leopold, L., & Friedman, J. M. (1994) · Nature · doi:10.1038/372425a0 · Cited by 13,419
Leptin and the regulation of body weight in mammals
Friedman, J. M., & Halaas, J. L. (1998) · Nature · doi:10.1038/27376 · Cited by 5,405
Weight-Reducing Effects of the Plasma Protein Encoded by the obese Gene
Halaas, J. L., Gajiwala, K. S., Maffei, M., Cohen, S. L., Chait, B. T., Rabinowitz, D., Lallone, R. L., Burley, S. K., & Friedman, J. M. (1995) · Science · doi:10.1126/science.7624777 · Cited by 4,451
Obesity as an independent risk factor for cardiovascular disease: a 26-year follow-up of participants in the Framingham Heart Study.
Hubert, H. B., Feinleib, M., McNamara, P. M., & Castelli, W. P. (1983) · Circulation · doi:10.1161/01.cir.67.5.968 · Cited by 4,241
The SREBP pathway: regulation of cholesterol metabolism by proteolysis of a membrane-bound transcription factor
Brown, M. S., & Goldstein, J. L. (1997) · Cell · doi:10.1016/s0092-8674(00)80213-5 · Cited by 3,834
Role of leptin in the neuroendocrine response to fasting
Ahima, R. S., Prabakaran, D., Mantzoros, C., Qu, D., Lowell, B., Maratos-Flier, E., & Flier, J. S. (1996) · Nature · doi:10.1038/382250a0 · Cited by 3,117
Trophic Action of Leptin on Hypothalamic Neurons That Regulate Feeding
Bouret, S. G., Draper, S. J., & Simerly, R. B. (2004) · Science · doi:10.1126/science.1095004 · Cited by 1,247
Leptin-Replacement Therapy for Lipodystrophy
Oral, E. A., Simha, V., Ruiz, E., Andewelt, A., Premkumar, A., Snell, P., Wagner, A. J., DePaoli, A. M., Reitman, M. L., Taylor, S. I., et al. (2002) · New England Journal of Medicine · doi:10.1056/nejmoa012437 · Cited by 1,247
Tissue-Specific Knockout of the Insulin Receptor in Pancreatic β Cells Creates an Insulin Secretory Defect Similar to that in Type 2 Diabetes
Kulkarni, R., Brüning, J. C., Winnay, J. N., Postic, C., Magnuson, M. A., & Kahn, C. R. (1999) · Cell · doi:10.1016/s0092-8674(00)80546-2 · Cited by 1,148
Self-citation
Leptin activation of Stat3 in the hypothalamus of wild-type and ob/ob mice but not db/db mice.
Vaisse, C., Halaas, J. L., Horvath, C. M., Darnell, J. E., Stoffel, M., & Friedman, J. M. (1996) · Nature Genetics · doi:10.1038/ng0996-95 · Cited by 1,086

Show all 47 references

Sorted by citations

Items 101–170 of 170

CNS Targets of Adipokines
Beall, C., Hanna, L., & Ellacott, K. L. J. (2017) · Comprehensive physiology · doi:10.1002/cphy.c160045 · Cited by 16
Roles of Gangliosides in Hypothalamic Control of Energy Balance: New Insights
Inamori, K., & Inokuchi, J. (2020) · International Journal of Molecular Sciences · doi:10.3390/ijms21155349 · Cited by 15
Role of Prolactin in the Metabolic Adaptations to Pregnancy and Lactation
Woodside, B. C., Augustine, R. A., Ladyman, S. R., Naef, L., & Grattan, D. R. (2008) · Elsevier eBooks · doi:10.1016/b978-0-12-374285-8.00016-0 · Cited by 16
Differences in metabolomic profiles of male db/db and s/s, leptin receptor mutant mice
Saadat, N., IglayReger, H. B., Myers, M. G., Bodary, P. F., & Gupta, S. V. (2012) · Physiological Genomics · doi:10.1152/physiolgenomics.00081.2011 · Cited by 15
Self-citation
Oncogenic role and therapeutic target of leptin signaling in colorectal cancer
Zhou, W., Tian, Y., Gong, H., Guo, S., & Luo, C. (2014) · Expert Opinion on Therapeutic Targets · doi:10.1517/14728222.2014.926889 · Cited by 15
An Overview of Rodent Models of Obesity and Type 2 Diabetes
Lutz, T. A. (2020) · Methods in molecular biology · doi:10.1007/978-1-0716-0385-7_2 · Cited by 14
Leptin receptor-induced STAT3-independent signaling pathways are protective against atherosclerosis in a murine model of obesity and hyperlipidemia
Luo, W., Bodary, P. F., Shen, Y., Wickenheiser, K. J., Öhman, M. K., Guo, C., Bahrou, K. L., Myers, M. G., & Eitzman, D. T. (2010) · Atherosclerosis · doi:10.1016/j.atherosclerosis.2010.10.009 · Cited by 14
Self-citation
Abdominal Obesity in Adult Nigerian Africans: Prevalence and Co-Occurrence with Cardio-Metabolic Risk Factors in a Resource Poor Setting of a Rural Hospital in Eastern Nigeria
Iloh, G. U. P. (2013) · American Journal of Health Research · doi:10.11648/j.ajhr.20130103.16 · Cited by 13
Photoperiod may regulate growth via leptin receptor A1 in the hypothalamus and saccus vasculosus of Atlantic salmon (Salmo salar)
Chi, L., Li, X., Liu, Q., & Liu, Y. (2019) · Animal Cells and Systems · doi:10.1080/19768354.2019.1595138 · Cited by 13
Endospanin 1 Determines the Balance of Leptin-Regulated Hypothalamic Functions
Roujeau, C., Jockers, R., & Dam, J. (2018) · Neuroendocrinology · doi:10.1159/000494557 · Cited by 12
A systematic review of preclinical studies exploring the role of insulin signalling in executive function and memory
Ottomana, A. M., Presta, M., O’Leary, A., Sullivan, M., Pisa, E., Laviola, G., Glennon, J. C., Zoratto, F., Slattery, D. A., & Macrı̀, S. (2023) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2023.105435 · Cited by 12
Experimental Animal Models: Tools to Investigate Antidiabetic Activity
Jain, A. K., Madhariya, R., Dixena, B., Ram, A., & Vyas, A. (2022) · Current Pharmaceutical Design · doi:10.2174/1381612829666221220115649 · Cited by 13
The Etiology of Hypertension in the Metabolic Syndrome Part Four: The Systemic Perspective – The Role of the Neuroendocrine and Immune Systems,and the Challenge of Integration
Publisher, B. S. P. B. S. (2006) · Current Vascular Pharmacology · doi:10.2174/157016106778521599 · Cited by 9
Leptin: 30 Years Later
Ahima, R. S., & Flier, J. S. (2025) · Annual Review of Physiology · doi:10.1146/annurev-physiol-042324-100259 · Cited by 10
Origen étnico y enfermedad cardiovascular
Rojas, J., Bermúdez, V., Leal, E., Aparicio, D., Peña, G., Acosta, L., Finol, F., Urdaneta, A., Colmenares, C., Almarza, J., et al. (2008) · Redalyc (Universidad Autónoma del Estado de México) · Cited by 9
Neurosteroids are reduced in diabetic neuropathy and may be associated with the development of neuropathic pain
Humble, S. R. (2016) · F1000Research · doi:10.12688/f1000research.9034.1 · Cited by 9
Podocytopathy in Obesity: Challenges of Living Large
Giannini, G., Kopp, J. B., & Rosenberg, A. Z. (2021) · Seminars in Nephrology · doi:10.1016/j.semnephrol.2021.06.003 · Cited by 8
Increased Hepatic Insulin Sensitivity in Mice Lacking Inhibitory Leptin Receptor Signals
Tom, R. Z., Sjögren, R. J. O., Vieira, E. C., Glund, S., Iglesias‐Gutiérrez, E., García-Rovés, P. M., Myers, M. G., & Björnholm, M. (2011) · Endocrinology · doi:10.1210/en.2010-0040 · Cited by 8
Self-citation
Immunotherapy against angiotensin II receptor ameliorated insulin resistance in a leptin receptor‐dependent manner
Zheng, J., Ding, J., Liao, M., Qiu, Z., Yuan, Q., Mai, W., Dai, Y., Zhang, H., Wu, H., Wang, Y., et al. (2020) · The FASEB Journal · doi:10.1096/fj.202000300r · Cited by 8
Trafic et signalisation du récepteur de la leptine
Dam, J. (2018) · Biologie Aujourd hui · doi:10.1051/jbio/2018020 · Cited by 7
Cellular and Molecular Players in the Interplay between Adipose Tissue and Breast Cancer
Reggiani, F., Falvo, P., & Bertolini, F. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22031359 · Cited by 7
The Etiology of Hypertension in the Metabolic Syndrome Part Two: The Gene-Environment Interaction
Publisher, B. S. P. B. S. (2006) · Current Vascular Pharmacology · doi:10.2174/157016106778521661 · Cited by 6
Effects of Curcumin on Neuroinflammation in Animal Models and in Patients with Alzheimer Disease
Farooqui, A. A. (2016) · Springer eBooks · doi:10.1007/978-3-319-15889-1_7 · Cited by 6
Leptin Receptor Signaling Regulates Protein Synthesis Pathways and Neuronal Differentiation in Pluripotent Stem Cells
Gupta, M. K., Vethe, H., Softic, S., Rao, T. N., Wagh, V., Shirakawa, J., Barsnes, H., Vaudel, M., Takatani, T., Kahraman, S., et al. (2020) · Stem Cell Reports · doi:10.1016/j.stemcr.2020.10.001 · Cited by 5
Self-citation
An Experimental Models (In-Vivo and In-Vitro) Used for the Study of Antidiabetic agents
Dash, S. L., Gupta, P., Dubey, A., Sahu, V. K., & Mishra, A. (2023) · Journal Of Advanced Zoology · doi:10.17762/jaz.v44i4.1461 · Cited by 5
Neuroendocrine Regulation of Food Intake
Watts, A. G. (2012) · Elsevier eBooks · doi:10.1016/b978-0-12-375097-6.10014-9 · Cited by 6
Effects of long-term exposure to aluminum in the hippocampus in the type 2 diabetes model rats
Nam, S. M., Yoo, D. Y., Kwon, H. J., Kim, J. W., Jung, H. Y., Kim, D. W., Seong, J. K., Hwang, I. K., & Yoon, Y. S. (2018) · Toxicology Research · doi:10.1039/c8tx00192h · Cited by 4
Review on In-vitro Techniques and In-vivo Animals Models for Screening Diabetes and Diabetic Complications
Shivam, S., Kumar, S., & Gupta, A. (2023) · Current Diabetes Reviews · doi:10.2174/1573399819666230413085341 · Cited by 3
Resequencing of Brazilian locally adapted cattle breeds revealed variants in candidate genes and transcription factors for meat fatty acid profile.
Vieira, J., Braga, L. G., Chud, T., Ferreira, P. H., Guimarães, S. E. F., Martins, M. F., Panetto, J. C. D. C., Machado, M. A., Silva, D. B. D. S., Bonafé, C. M., et al. (2024) · Journal of animal breeding and genetics = Zeitschrift fur Tierzuchtung und Zuchtungsbiologie · doi:10.1111/jbg.12869 · Cited by 3
Evidence for leptin receptor immunoreactivity in the gastrointestinal tract and gastric leptin regulation in the rainbow trout (Oncorhynchus mykiss)
Imperatore, R., Coccia, E., D’Angelo, L., Varricchio, E., de Girolamo, P., & Paolucci, M. (2018) · Annals of Anatomy - Anatomischer Anzeiger · doi:10.1016/j.aanat.2018.07.007 · Cited by 3
Effect of exogenous leptin on serum levels of lipids, glucose, renal and hepatic variables in both genders of obese and streptozotocin-induced diabetic rats.
Hayatdavoudi, P., Ghasemi, M., Zendehbad, B., Soukhtanloo, M., Golshan, A., & Hadjzadeh, M. (2015) · PubMed Central · Cited by 3
Conjugated Linoleic Acid and Weight Control
Kong, Z. (2007) · CRC Press eBooks · doi:10.1201/9781420005479.ch29 · Cited by 3
Leptin and the Regulation of Feeding
Myers, M. G. (2006) · Elsevier eBooks · doi:10.1016/b978-012369442-3/50138-0 · Cited by 2
Self-citation
Obesity and Cardiometabolic Defects in Heart Failure Pathology
Halade, G. V., & Kain, V. (2017) · Comprehensive physiology · doi:10.1002/j.2040-4603.2017.tb00788.x · Cited by 2
Leptin and Neuroendocrinology
Sahu, A. (2006) · Springer eBooks · doi:10.1007/978-0-387-31416-7_4 · Cited by 2
Biosensors used in diabetes management
Askari, V. R., Fadaei, M. S., Saberifar, M., Fadaei, M. R., Rahimi, V. B., Hasnain, M. S., & Nayak, A. K. (2025) · Elsevier eBooks · doi:10.1016/b978-0-443-21592-6.00007-0 · Cited by 1
Molecular Aspects of Obesity and Insulin Resistance in Metabolic Syndrome and Neurological Disorders
Farooqui, A. A. (2013) · Springer eBooks · doi:10.1007/978-1-4614-7318-3_5 · Cited by 1
The Relationship Between Elevations in Glucocorticoids and Diabetes Development in Rats on Skeletal Muscle Insulin Resistance and the Microvasculature
Dunford, E. C. (2016) · YorkSpace (York University) · Cited by 1
Leptin regulates glucose homeostasis via the canonical WNT pathwayPreprint
Kamstra, K., Rizwan, M. Z., Horsfield, J. A., Pretz, D., Shepherd, P. R., Grattan, D. R., & Tups, A. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.02.16.431518 · Cited by 1
The Role of ER Stress and the Unfolded Protein Response in Obesity Associated Type 2 Diabetes
Omikorede, O. (2012) · Leicester Research Archive (University of Leicester) · Cited by 1
Mapping the Neural Mechanisms by which Leptin Regulates Distinct Physiological Functions.
Louis, G. W. (2010) · Deep Blue (University of Michigan)
Multiple loci of intra- and extra-hypothalamic leptin receptor expression and action in the mouse
Leshan, R. L. (2009) · Deep Blue (University of Michigan)
Améliorer la sensibilité à la leptine vers un remède contre l’obésité
Dam, J., Vauthier, V., & Jockers, R. (2008) · Obésité · doi:10.1007/s11690-008-0151-3
Roles of Jak2 in Leptin Action: From Molecular Signaling to Physiology.
Robertson, S. (2011) · Deep Blue (University of Michigan)
Central and peripheral mechanisms regulating energy and glucose homeostasis
Tom, R. Z. (2013) · Figshare
A Multivariate Regression Model for Continuous Genetic Traits
Yuan, A., & Bonney, G. E. (2006) · Journal of the Royal Statistical Society Series C (Applied Statistics) · doi:10.1111/j.1467-9876.2006.00552.x
El mecanismo molecular de la regulación de la contracción muscular
Padrón, R. (2008) · Redalyc (Universidad Autónoma del Estado de México)
s/s, leptin receptor mutant mice Differences in metabolomic profiles of male db/db and
Gupta, V., Saadat, N., IglayReger, H. B., & Bodary, P. F. (2015)
Modulação do metabolismo muscular da glicose pela ação hipotalâmica da leptina
Roman, E. A. D. F. R. (2011) · doi:10.47749/t/unicamp.2011.829153
The Apparent Increase in Insulin Sensitivity of Leptin-Treated Rats Appears to be Due to a Decrease in Blood Glucose Concentrations in Response to Fasting
Gragg, M. (2007)
Control of Appetite/Satiety and Energy Balance
Elmquist, J. K., & Horton, J. D. (2015) · Wiley eBooks · doi:10.1002/9781118512074.ch28
Unraveling Novel Leptin-Dependent Signaling Pathways in the Basomedial Hypothalamus.
Villanueva, E. C. (2010) · Deep Blue (University of Michigan)
The effects of distinct fatty acids on central leptin sensitivity, hypothalamic inflammation, and central-regulated hepatic metabolism
Cheng, L. (2015) · Research Online (University of Wollongong)
The Interrelationship of Obesity, Pain, and Diet/Nutrition
Rodgers, H. M. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-805186-3.00012-6
Efeito da dieta hiperlipídica sobre a responsividade de neurônios kisspeptidérgicos à leptina
Venancio-Brochi, J. C. (2016) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2016.tde-06012016-164539
THE IMPACT OF OBESITY ON PROTEINS INVOLVED IN DRUG METABOLISM
Al-Agili, M. (2017) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r31n7z188
The Effect and Mechanism of Light on the Growth, Food Intake, and Gonad Development of Atlantic Salmon (Salmo salar) Reared in RAS
Liu, Y., Gao, X., & Chi, L. (2019) · Solid state lighting technology and application series · doi:10.1007/978-3-319-99211-2_15
Impact of Obesity on Metabolism of Some Selected Anesthetic Agents
Nebaihi, H. M. S. A. (2019) · ERA: Education and Research Archive (University of Alberta) · doi:10.7939/r3-bc3j-pc90
Obese Zucker Rats as a Reverse Translational Model of Human Left Ventricular Hypertrophy
Newman, M. S. (2020) · The Research Repository @ WVU (West Virginia University) · doi:10.33915/etd.7982
Insulin-induced endothelial cell proliferation and viability in stretched murine skin and cell culture
Shrader, C. D. (2007) · doi:10.33915/etd.2584
Identification of hypothalamic sites that control puberty onset and sexual maturation
Greenwald-Yarnell, M. L. (2013) · Deep Blue (University of Michigan)
THE ROLE OF LEPTIN AND ADIPONEKTIN IN FORMATION INSULIN RESISTANCE IN CHILDREN OF PUBERTIC AGE, WHO SUFFER FROM OBESITY
Shlyakhova, N. V. (2011) · PROBLEMS OF ENDOCRINE PATHOLOGY · doi:10.21856/j-pep.2011.4.08
Participação da via da STAT3 em neurônios POMC do hipotálamo na homeostase energética
Volpi, R. E. (2020) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/d.17.2020.tde-30092022-095827
Avaliação do papel do TGF-ß1 e da microglia na resposta inflamatória hipotalâmica induzida por ácidos graxos saturados
Mendes, N. F. (2021) · doi:10.47749/t/unicamp.2021.1236731
An overview of botanical approaches for managing obesity
Sindhwani, R., Singh, P. A., Hazra, S., & Kumari, S. (2024) · Pharmacological Research - Natural Products · doi:10.1016/j.prenap.2024.100115
CNS Targets of Adipokines
Beall, C., Hanna, L., & Ellacott, K. L. J. (2017) · Comprehensive physiology · doi:10.1002/j.2040-4603.2017.tb00781.x
Role of the Yeast Ste20 Protein Kinase Ortholog Map4k4 in Adipose Tissue Function: A Dissertation
Guntur, K. (2011) · The Journal of the American Medical Association (JAMA) Network (American Medical Association) · doi:10.13028/1m28-xp71
Tissu adipeux et résistance tumorale aux thérapies ciblées
Geneste, A. (2018) · theses.fr (ABES) · doi:10.70675/1521e85cz8c2fz4c73za577z0f6537a4e8de
Stevioside enhances skeletal muscle glucose uptake in high-fat diet-induced prediabetic mice via the JAK2/STAT3/IL6ra axis
Zhang, C., Kang, L., Peng, M., Li, K., Li, Z., Wang, R., Qu, H., & Li, G. (2026) · Food Production Processing and Nutrition · doi:10.1186/s43014-026-00438-0
The effects of obesity and surgically-induced weight loss on exercise ventilation: influence of central adiposity and serum leptin
Herrick, J. E. (2009) · VCU Scholars Compass (Virginia Commonwealth University) · doi:10.25772/08zr-f665

Authors: Bates, S. H., Kulkarni, R. N., Seifert, M., & Myers, M. G.
Affiliations: University of Michigan (US)
Joslin Diabetes Center (US)
Corresponding author: Myers, Martin G.
ORCID: Kulkarni, Rohit N.
Myers, Martin G.
Venue: Cell Metabolism
Publisher: Elsevier BV
Published: 2005-03
Volume: 1
Issue: 3
Pages: 169-178
ISSN: 1550-4131 (ISSN-L)
DOI: 10.1016/j.cmet.2005.02.001
OpenAlex: W2122551774
Cited by: 173
References: 47
Citations by year: 2026: 1 · 2025: 3 · 2024: 2 · 2023: 5 · 2022: 1 · 2021: 5 · 2020: 11 · 2019: 5 · 2018: 11 · 2017: 14 · 2016: 7 · 2015: 6 · 2014: 7 · 2013: 10 · 2012: 11
FWCI: 5.38
Type: journal article
Language: en
Open access: bronze
doi.org
Licence: www.elsevier.com/tdm/userlicense/1.0/ (tdm)
www.elsevier.com/open-access/userlicense/1.0/ (vor, 3060 d)
Locations: Cell Metabolism (publishedVersion)
PubMed (publishedVersion)
Funders: U.S. Public Health Service (56731)
National Institute of Diabetes and Digestive and Kidney Diseases (DK 57768, R01DK057768)
Topics: Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Regulation of Appetite and Obesity
Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Adipokines, Inflammation, and Metabolic Diseases
Life Sciences › Immunology and Microbiology › Immunology › Cytokine Signaling Pathways and Interactions
Keywords: leptin, leptin receptor, STAT3 signaling, glucose homeostasis, insulin resistance, impaired glucose tolerance, db/db mice, caloric restriction, hyperphagia, neuroendocrine dysfunction, obesity
MeSH terms: Animals, Body Composition, Body Weight, DNA-Binding Proteins, Glucose, Homeostasis, Hyperglycemia, Insulin Resistance, Male, Mice, Mutant Strains, Receptors, Cell Surface, Signal Transduction, Trans-Activators, Amino Acid Substitution, Caloric Restriction, STAT3 Transcription Factor, Mice, Receptors, Leptin

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

Roles for leptin receptor/STAT3-dependent and -independent signals in the regulation of glucose homeostasis

Abstract

Overview

Integrity signals

Verification

Claims the paper makes

Claims other papers make about this one

Citations

Cites

Cited by

Related

Metadata

Record

About these checks